Development and validation of a genetic probability for venous thromboembolism

Factor V Leiden (FVL) and prothrombin gene mutations (PGMs), as well as recently developed polygenic scores (PGSs), have been consistently associated with venous thromboembolism (VTE) risk in European ancestry populations. This study aimed to develop an optimized risk-assessment tool combining mutat...

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Vydáno v:	Research and practice in thrombosis and haemostasis Ročník 9; číslo 4; s. 102876
Hlavní autoři:	Shi, Zhuqing, Mulford, Ashley J., Tran, Huy, Filipczak, Michal, Gao, Song, Xie, Stevie, Lobel, Jason, Wei, Jun, Rifkin, Andrew S., Ashworth, Annabelle, Zheng, Siqun Lilly, Wiske, Clay, Duggan, David, Helfand, Brian T., Qamar, Arman, Sanders, Alan R., Tafur, Alfonso J., Xu, Jianfeng
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Elsevier Inc 01.05.2025 Elsevier
Témata:	factor V Leiden (FVL) Hematology Original polygenic score (PGS) prothrombin gene mutations (PGM) reclassification venous thromboembolism (VTE) factor V Leiden (FVL) prothrombin gene mutations (PGM) polygenic score (PGS) venous thromboembolism (VTE) reclassification
ISSN:	2475-0379, 2475-0379
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