GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current

The CB(1) cannabinoid receptor mediates many of the psychoactive effects of Delta(9)THC, the principal active component of cannabis. However, ample evidence suggests that additional non-CB(1)/CB(2) receptors may contribute to the behavioral, vascular, and immunological actions of Delta(9)THC and end...

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Vydané v:	Proceedings of the National Academy of Sciences - PNAS Ročník 105; číslo 7; s. 2699
Hlavní autori:	Lauckner, Jane E, Jensen, Jill B, Chen, Huei-Ying, Lu, Hui-Chen, Hille, Bertil, Mackie, Ken
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 19.02.2008
Predmet:	Actins - metabolism Calcium - metabolism Cannabinoid Receptor Antagonists Cell Line Cytoskeleton - metabolism Electrophysiology Enzyme Activation GTP-Binding Protein alpha Subunits, G12-G13 - metabolism GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism Humans Inositol 1,4,5-Trisphosphate Receptors - metabolism MAP Kinase Signaling System Mitogen-Activated Protein Kinase 1 - metabolism Mitogen-Activated Protein Kinase 3 - metabolism Patch-Clamp Techniques Phosphoinositide Phospholipase C - metabolism Piperidines - pharmacology Potassium - metabolism Pyrazoles - pharmacology Receptors, Cannabinoid - genetics Receptors, Cannabinoid - metabolism rhoA GTP-Binding Protein - metabolism
ISSN:	1091-6490, 1091-6490
On-line prístup:	Zistit podrobnosti o prístupe
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