New insights into the interplay between long non‐coding RNAs and RNA‐binding proteins in cancer

With the development of proteomics and epigenetics, a large number of RNA‐binding proteins (RBPs) have been discovered in recent years, and the interaction between long non‐coding RNAs (lncRNAs) and RBPs has also received increasing attention. It is extremely important to conduct in‐depth research o...

Full description

Saved in:
Bibliographic Details
Published in:Cancer communications (London, England) Vol. 42; no. 2; pp. 117 - 140
Main Authors: Yao, Zi‐Ting, Yang, Yan‐Ming, Sun, Miao‐Miao, He, Yan, Liao, Long, Chen, Kui‐Sheng, Li, Bin
Format: Journal Article
Language:English
Published: United States John Wiley & Sons, Inc 01.02.2022
John Wiley and Sons Inc
Wiley
Subjects:
Binding sites
cancer
cancer epigenetics
Cell cycle
Cyclin-dependent kinases
Dehydrogenases
Epigenesis, Genetic
Epigenetics
Gene expression
Genomes
Growth factors
Humans
interaction network
Kinases
lncRNA‐RBP
long non‐coding RNA
Metastasis
MicroRNAs
Neoplasms - genetics
Neoplasms - metabolism
Prostate cancer
Proteins
Review
Reviews
RNA polymerase
RNA, Long Noncoding - genetics
RNA, Long Noncoding - metabolism
RNA-Binding Proteins - genetics
RNA-Binding Proteins - metabolism
RNA‐binding protein
Signal transduction
Stem cells
treatment strategy
RNA-binding protein
interaction network
treatment strategy
cancer
long non-coding RNA
cancer epigenetics
lncRNA-RBP
ISSN:2523-3548, 2523-3548
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Abstract With the development of proteomics and epigenetics, a large number of RNA‐binding proteins (RBPs) have been discovered in recent years, and the interaction between long non‐coding RNAs (lncRNAs) and RBPs has also received increasing attention. It is extremely important to conduct in‐depth research on the lncRNA‐RBP interaction network, especially in the context of its role in the occurrence and development of cancer. Increasing evidence has demonstrated that lncRNA‐RBP interactions play a vital role in cancer progression; therefore, targeting these interactions could provide new insights for cancer drug discovery. In this review, we discussed how lncRNAs can interact with RBPs to regulate their localization, modification, stability, and activity and discussed the effects of RBPs on the stability, transport, transcription, and localization of lncRNAs. Moreover, we explored the regulation and influence of these interactions on lncRNAs, RBPs, and downstream pathways that are related to cancer development, such as N6‐methyladenosine (m6A) modification of lncRNAs. In addition, we discussed how the lncRNA‐RBP interaction network regulates cancer cell phenotypes, such as proliferation, apoptosis, metastasis, drug resistance, immunity, tumor environment, and metabolism. Furthermore, we summarized the therapeutic strategies that target the lncRNA‐RBP interaction network. Although these treatments are still in the experimental stage and various theories and processes are still being studied, we believe that these strategies may provide new ideas for cancer treatment.
AbstractList With the development of proteomics and epigenetics, a large number of RNA-binding proteins (RBPs) have been discovered in recent years, and the interaction between long non-coding RNAs (lncRNAs) and RBPs has also received increasing attention. It is extremely important to conduct in-depth research on the lncRNA-RBP interaction network, especially in the context of its role in the occurrence and development of cancer. Increasing evidence has demonstrated that lncRNA-RBP interactions play a vital role in cancer progression; therefore, targeting these interactions could provide new insights for cancer drug discovery. In this review, we discussed how lncRNAs can interact with RBPs to regulate their localization, modification, stability, and activity and discussed the effects of RBPs on the stability, transport, transcription, and localization of lncRNAs. Moreover, we explored the regulation and influence of these interactions on lncRNAs, RBPs, and downstream pathways that are related to cancer development, such as N6-methyladenosine (m6A) modification of lncRNAs. In addition, we discussed how the lncRNA-RBP interaction network regulates cancer cell phenotypes, such as proliferation, apoptosis, metastasis, drug resistance, immunity, tumor environment, and metabolism. Furthermore, we summarized the therapeutic strategies that target the lncRNA-RBP interaction network. Although these treatments are still in the experimental stage and various theories and processes are still being studied, we believe that these strategies may provide new ideas for cancer treatment.
With the development of proteomics and epigenetics, a large number of RNA-binding proteins (RBPs) have been discovered in recent years, and the interaction between long non-coding RNAs (lncRNAs) and RBPs has also received increasing attention. It is extremely important to conduct in-depth research on the lncRNA-RBP interaction network, especially in the context of its role in the occurrence and development of cancer. Increasing evidence has demonstrated that lncRNA-RBP interactions play a vital role in cancer progression; therefore, targeting these interactions could provide new insights for cancer drug discovery. In this review, we discussed how lncRNAs can interact with RBPs to regulate their localization, modification, stability, and activity and discussed the effects of RBPs on the stability, transport, transcription, and localization of lncRNAs. Moreover, we explored the regulation and influence of these interactions on lncRNAs, RBPs, and downstream pathways that are related to cancer development, such as N6-methyladenosine (m6A) modification of lncRNAs. In addition, we discussed how the lncRNA-RBP interaction network regulates cancer cell phenotypes, such as proliferation, apoptosis, metastasis, drug resistance, immunity, tumor environment, and metabolism. Furthermore, we summarized the therapeutic strategies that target the lncRNA-RBP interaction network. Although these treatments are still in the experimental stage and various theories and processes are still being studied, we believe that these strategies may provide new ideas for cancer treatment.With the development of proteomics and epigenetics, a large number of RNA-binding proteins (RBPs) have been discovered in recent years, and the interaction between long non-coding RNAs (lncRNAs) and RBPs has also received increasing attention. It is extremely important to conduct in-depth research on the lncRNA-RBP interaction network, especially in the context of its role in the occurrence and development of cancer. Increasing evidence has demonstrated that lncRNA-RBP interactions play a vital role in cancer progression; therefore, targeting these interactions could provide new insights for cancer drug discovery. In this review, we discussed how lncRNAs can interact with RBPs to regulate their localization, modification, stability, and activity and discussed the effects of RBPs on the stability, transport, transcription, and localization of lncRNAs. Moreover, we explored the regulation and influence of these interactions on lncRNAs, RBPs, and downstream pathways that are related to cancer development, such as N6-methyladenosine (m6A) modification of lncRNAs. In addition, we discussed how the lncRNA-RBP interaction network regulates cancer cell phenotypes, such as proliferation, apoptosis, metastasis, drug resistance, immunity, tumor environment, and metabolism. Furthermore, we summarized the therapeutic strategies that target the lncRNA-RBP interaction network. Although these treatments are still in the experimental stage and various theories and processes are still being studied, we believe that these strategies may provide new ideas for cancer treatment.
Abstract With the development of proteomics and epigenetics, a large number of RNA‐binding proteins (RBPs) have been discovered in recent years, and the interaction between long non‐coding RNAs (lncRNAs) and RBPs has also received increasing attention. It is extremely important to conduct in‐depth research on the lncRNA‐RBP interaction network, especially in the context of its role in the occurrence and development of cancer. Increasing evidence has demonstrated that lncRNA‐RBP interactions play a vital role in cancer progression; therefore, targeting these interactions could provide new insights for cancer drug discovery. In this review, we discussed how lncRNAs can interact with RBPs to regulate their localization, modification, stability, and activity and discussed the effects of RBPs on the stability, transport, transcription, and localization of lncRNAs. Moreover, we explored the regulation and influence of these interactions on lncRNAs, RBPs, and downstream pathways that are related to cancer development, such as N6‐methyladenosine (m6A) modification of lncRNAs. In addition, we discussed how the lncRNA‐RBP interaction network regulates cancer cell phenotypes, such as proliferation, apoptosis, metastasis, drug resistance, immunity, tumor environment, and metabolism. Furthermore, we summarized the therapeutic strategies that target the lncRNA‐RBP interaction network. Although these treatments are still in the experimental stage and various theories and processes are still being studied, we believe that these strategies may provide new ideas for cancer treatment.
Author Yang, Yan‐Ming
He, Yan
Chen, Kui‐Sheng
Li, Bin
Yao, Zi‐Ting
Sun, Miao‐Miao
Liao, Long
AuthorAffiliation 2 Department of Pathology Henan Key Laboratory of Tumor Pathology the First Affiliated Hospital of Zhengzhou University Zhengzhou Henan 450001 P. R. China
3 Ministry of Education Key Laboratory of Tumor Molecular Biology and Guangdong Provincial Key Laboratory of Bioengineering Medicine National Engineering Research Center of Genetic Medicine Institute of Biomedicine College of Life Science and Technology Jinan University Guangzhou Guangdong 510632 P. R. China
4 Key Laboratory of Biological Targeting Diagnosis Therapy and Rehabilitation of Guangdong Higher Education Institutes the Fifth Affiliated Hospital of Guangzhou Medical University Guangzhou Guangdong 510700 P. R. China
1 Ministry of Education Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes Institute of Life and Health Engineering Jinan University Guangzhou Guangdong 510632 P. R. China
AuthorAffiliation_xml – name: 2 Department of Pathology Henan Key Laboratory of Tumor Pathology the First Affiliated Hospital of Zhengzhou University Zhengzhou Henan 450001 P. R. China
– name: 3 Ministry of Education Key Laboratory of Tumor Molecular Biology and Guangdong Provincial Key Laboratory of Bioengineering Medicine National Engineering Research Center of Genetic Medicine Institute of Biomedicine College of Life Science and Technology Jinan University Guangzhou Guangdong 510632 P. R. China
– name: 4 Key Laboratory of Biological Targeting Diagnosis Therapy and Rehabilitation of Guangdong Higher Education Institutes the Fifth Affiliated Hospital of Guangzhou Medical University Guangzhou Guangdong 510700 P. R. China
– name: 1 Ministry of Education Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes Institute of Life and Health Engineering Jinan University Guangzhou Guangdong 510632 P. R. China
Author_xml – sequence: 1
  givenname: Zi‐Ting
  surname: Yao
  fullname: Yao, Zi‐Ting
  organization: Jinan University
– sequence: 2
  givenname: Yan‐Ming
  surname: Yang
  fullname: Yang, Yan‐Ming
  organization: Jinan University
– sequence: 3
  givenname: Miao‐Miao
  surname: Sun
  fullname: Sun, Miao‐Miao
  organization: the First Affiliated Hospital of Zhengzhou University
– sequence: 4
  givenname: Yan
  surname: He
  fullname: He, Yan
  organization: the Fifth Affiliated Hospital of Guangzhou Medical University
– sequence: 5
  givenname: Long
  surname: Liao
  fullname: Liao, Long
  organization: the Fifth Affiliated Hospital of Guangzhou Medical University
– sequence: 6
  givenname: Kui‐Sheng
  surname: Chen
  fullname: Chen, Kui‐Sheng
  email: chenksh2002@163.com
  organization: the First Affiliated Hospital of Zhengzhou University
– sequence: 7
  givenname: Bin
  orcidid: 0000-0002-8979-610X
  surname: Li
  fullname: Li, Bin
  email: lib2128@163.com
  organization: the Fifth Affiliated Hospital of Guangzhou Medical University
BackLink https://www.ncbi.nlm.nih.gov/pubmed/35019235$$D View this record in MEDLINE/PubMed
BookMark eNp9ks1qGzEQgEVJaVI3lz5AWeilFJxqpdWudCkY059ASKHkLrTSrC2zllxpHeNbH6HP2CfprJ2GJJSeNJr95tNoNS_JSYgBCHld0ouSUvbBGssuSsZE9YycMcH4lItKnjyIT8l5zitKaamkqgR_QU65wA3j4ozYa9gVPmS_WA4ZgyEWwxLGANKmN_uihWEHEIo-hkWBZ__--ctG53Hz_XqWCxPcGGC29eGQ3qQ4ABrRUVgTLKRX5Hln-gznd-uE3Hz-dDP_Or369uVyPruaWiHLairrhsmmtkoIVTvZOeCKdU4qJtuGlg00tnHYtmt5ZVgDVvKOlZUCQTmVwCfk8qh10az0Jvm1SXsdjdeHREwLbdLgbQ-6VSAlE7IdXR2zuDbMAVUVBddCja6PR9dm267BWQhDMv0j6eMvwS_1It5q1DKhKhS8uxOk-GMLedBrny30vQkQt1mzGm9S1gxfYULePkFXcZsC_imkkMNGKUfqzcOO7lv5-5QIvD8CNsWcE3T3SEn1OCp6HBV9GBWE6RPY-sEMPo638f2_S8pjyc73sP-PXM9nc3as-QNH6dCq
CitedBy_id crossref_primary_10_3389_fonc_2022_867670
crossref_primary_10_1016_j_jpedsurg_2024_07_018
crossref_primary_10_1016_j_atherosclerosis_2023_01_008
crossref_primary_10_1016_j_omtn_2022_04_016
crossref_primary_10_1093_carcin_bgad097
crossref_primary_10_1002_cnr2_70115
crossref_primary_10_3390_biom13111674
crossref_primary_10_1038_s41420_023_01352_x
crossref_primary_10_3389_fimmu_2024_1469918
crossref_primary_10_1002_advs_202506718
crossref_primary_10_1016_j_ijbiomac_2024_139445
crossref_primary_10_1038_s41467_024_53493_x
crossref_primary_10_1016_j_critrevonc_2024_104271
crossref_primary_10_1002_jgm_3662
crossref_primary_10_1007_s12012_024_09922_w
crossref_primary_10_1007_s11883_024_01250_2
crossref_primary_10_1080_15376516_2023_2197489
crossref_primary_10_1038_s41598_025_07213_0
crossref_primary_10_1111_1759_7714_15037
crossref_primary_10_1016_j_prp_2024_155125
crossref_primary_10_1002_cbf_3953
crossref_primary_10_32604_or_2024_047626
crossref_primary_10_3390_cancers15245781
crossref_primary_10_1007_s12672_025_03189_5
crossref_primary_10_1016_j_prp_2023_154657
crossref_primary_10_1096_fj_202400236RR
crossref_primary_10_3892_ijo_2022_5453
crossref_primary_10_1093_toxres_tfae096
crossref_primary_10_1158_0008_5472_CAN_24_4784
crossref_primary_10_1002_jbt_23384
crossref_primary_10_1016_j_semcancer_2022_05_013
crossref_primary_10_1016_j_exer_2024_109870
crossref_primary_10_1016_j_jmb_2025_169357
crossref_primary_10_1002_cam4_7200
crossref_primary_10_1007_s10528_023_10597_1
crossref_primary_10_31083_j_fbl2910362
crossref_primary_10_1002_mc_23903
crossref_primary_10_1093_gigascience_giaf079
crossref_primary_10_1093_mr_roae015
crossref_primary_10_1002_cam4_70169
crossref_primary_10_2147_IJWH_S365943
crossref_primary_10_3390_ijms252111337
crossref_primary_10_1002_ctm2_70257
crossref_primary_10_7555_JBR_38_20240190
crossref_primary_10_1007_s12032_023_02263_8
crossref_primary_10_1016_j_cellsig_2023_110923
crossref_primary_10_1016_j_prp_2023_154887
crossref_primary_10_1016_j_prp_2024_155218
crossref_primary_10_1016_j_gene_2025_149606
crossref_primary_10_1016_j_abb_2025_110619
crossref_primary_10_1016_j_prp_2024_155294
crossref_primary_10_1128_jvi_01183_23
crossref_primary_10_1021_jacs_4c05205
crossref_primary_10_3390_genes14101856
crossref_primary_10_3389_fmolb_2024_1520498
crossref_primary_10_1007_s10142_024_01436_6
crossref_primary_10_1007_s11010_025_05250_x
crossref_primary_10_3389_fgene_2023_1176174
crossref_primary_10_3390_biomedicines12112520
crossref_primary_10_1007_s12013_024_01287_9
crossref_primary_10_1186_s40001_025_02888_7
crossref_primary_10_1007_s12013_024_01317_6
crossref_primary_10_1007_s12672_024_01679_6
crossref_primary_10_1007_s00210_025_04402_6
crossref_primary_10_1016_j_abb_2024_110175
crossref_primary_10_1007_s12672_025_02174_2
crossref_primary_10_3892_ijmm_2025_5605
crossref_primary_10_1016_j_jbc_2023_104658
crossref_primary_10_1016_j_jare_2024_08_030
crossref_primary_10_3892_ijo_2023_5562
crossref_primary_10_1016_j_ecoenv_2024_117064
crossref_primary_10_1186_s12935_024_03440_z
crossref_primary_10_1111_aji_13864
crossref_primary_10_1186_s13046_023_02827_6
crossref_primary_10_1097_HJH_0000000000004104
crossref_primary_10_1038_s41419_024_07020_x
crossref_primary_10_1158_1541_7786_MCR_23_0701
crossref_primary_10_1016_j_ccr_2024_215791
crossref_primary_10_1016_j_intimp_2024_112297
crossref_primary_10_3390_ijms241713617
crossref_primary_10_3390_biom15050627
crossref_primary_10_1016_j_gendis_2025_101788
crossref_primary_10_1016_j_yexcr_2025_114649
crossref_primary_10_3389_fphys_2022_953880
crossref_primary_10_1016_j_arr_2023_101958
crossref_primary_10_3389_fvets_2024_1356259
crossref_primary_10_3390_ncrna10020024
crossref_primary_10_1002_jper_11394
crossref_primary_10_1007_s12672_024_01133_7
crossref_primary_10_1515_revneuro_2023_0155
crossref_primary_10_3892_or_2024_8801
crossref_primary_10_2147_IJN_S499381
crossref_primary_10_1080_00365521_2025_2450024
crossref_primary_10_2174_1574893618666230707103956
crossref_primary_10_3390_ani12091059
crossref_primary_10_2147_JIR_S489682
crossref_primary_10_3389_fcell_2024_1442193
crossref_primary_10_1016_j_prp_2024_155619
crossref_primary_10_3389_fimmu_2025_1574507
crossref_primary_10_3389_fonc_2025_1578927
crossref_primary_10_1016_j_gene_2025_149216
crossref_primary_10_1096_fj_202500389R
crossref_primary_10_1002_mco2_141
crossref_primary_10_1007_s13402_025_01086_1
crossref_primary_10_1016_j_intimp_2024_111876
crossref_primary_10_1016_j_lfs_2023_122322
crossref_primary_10_3389_fonc_2023_1287808
crossref_primary_10_1111_jcmm_70296
crossref_primary_10_1111_jcmm_70453
crossref_primary_10_1186_s13148_022_01361_0
crossref_primary_10_1155_2023_4622584
crossref_primary_10_1002_adbi_202300642
crossref_primary_10_1016_j_biosystems_2023_105021
crossref_primary_10_1016_j_celrep_2024_114240
crossref_primary_10_1016_j_drup_2025_101245
crossref_primary_10_1016_j_compbiomed_2024_108198
crossref_primary_10_1007_s12035_024_04646_y
crossref_primary_10_3389_fonc_2025_1552773
crossref_primary_10_1007_s11103_023_01360_6
crossref_primary_10_1096_fj_202500351R
crossref_primary_10_1186_s12943_024_01962_8
crossref_primary_10_1016_j_canlet_2024_217004
crossref_primary_10_1186_s12935_023_02955_1
crossref_primary_10_3390_biom14091056
crossref_primary_10_1038_s41419_025_07456_9
crossref_primary_10_1007_s10238_024_01491_0
crossref_primary_10_3389_fonc_2024_1511240
crossref_primary_10_4103_NRR_NRR_D_23_01355
crossref_primary_10_1007_s12672_024_01051_8
crossref_primary_10_1186_s11658_025_00736_4
crossref_primary_10_1186_s12967_023_04373_3
crossref_primary_10_3390_cimb47060462
crossref_primary_10_1007_s10142_025_01617_x
crossref_primary_10_1038_s41419_023_06137_9
crossref_primary_10_3389_fonc_2024_1522491
crossref_primary_10_1016_j_prp_2024_155412
crossref_primary_10_1186_s13046_025_03368_w
crossref_primary_10_1186_s12885_025_14497_y
crossref_primary_10_1016_j_prp_2024_155778
crossref_primary_10_1002_advs_202411834
crossref_primary_10_1186_s12935_024_03408_z
crossref_primary_10_1016_j_urolonc_2023_10_012
crossref_primary_10_1002_advs_202305631
crossref_primary_10_5534_wjmh_250125
crossref_primary_10_1007_s12672_023_00764_6
crossref_primary_10_1007_s10620_023_08206_7
crossref_primary_10_1007_s11033_022_07707_4
crossref_primary_10_1016_j_heliyon_2023_e23161
crossref_primary_10_1016_j_cellsig_2023_110854
crossref_primary_10_3389_fphar_2024_1432490
crossref_primary_10_1016_j_tranon_2023_101661
crossref_primary_10_2147_PGPM_S422083
crossref_primary_10_1615_JEnvironPatholToxicolOncol_2024056566
crossref_primary_10_1038_s41467_025_62433_2
crossref_primary_10_1016_j_ijbiomac_2025_144260
crossref_primary_10_3892_mmr_2025_13667
crossref_primary_10_1007_s10238_025_01678_z
crossref_primary_10_3724_abbs_2025032
crossref_primary_10_1016_j_biopha_2023_114314
crossref_primary_10_1007_s10528_023_10590_8
crossref_primary_10_3892_ol_2025_15048
crossref_primary_10_1080_10985549_2024_2325527
crossref_primary_10_1016_j_canlet_2025_217532
crossref_primary_10_3390_bioengineering9110615
crossref_primary_10_1016_j_exer_2025_110492
crossref_primary_10_1016_j_molmet_2024_102011
crossref_primary_10_3389_fimmu_2025_1577261
crossref_primary_10_7717_peerj_19284
crossref_primary_10_1016_j_cca_2025_120242
crossref_primary_10_1186_s11658_024_00568_8
crossref_primary_10_1167_iovs_66_5_20
crossref_primary_10_1186_s12935_024_03499_8
crossref_primary_10_2147_BCTT_S454054
crossref_primary_10_1016_j_intimp_2023_110728
crossref_primary_10_1016_j_prp_2023_154709
Cites_doi 10.1093/nar/gky214
10.1038/cddis.2016.142
10.1371/journal.pcbi.1004049
10.1016/j.molcel.2011.08.018
10.1002/stem.2937
10.3390/ijms19102958
10.1038/nature12730
10.1038/s41418-019-0461-z
10.1002/cam4.948
10.1038/nature19342
10.1093/nar/gkt182
10.1016/S0002-9440(10)64779-7
10.1101/gr.132159.111
10.1038/s41419-021-03413-4
10.1038/s41389-019-0182-7
10.1016/j.cell.2013.01.011
10.1038/s41392-020-00275-8
10.1158/1535-7163.MCT-14-0492
10.7150/ijbs.28048
10.1016/S0960-894X(98)00366-7
10.1038/nrc865
10.1111/jcmm.15373
10.1038/nmeth.4066
10.1038/s41418-018-0084-9
10.3892/etm.2013.933
10.1016/j.celrep.2015.08.069
10.1002/hep.26537
10.1093/jnci/djz134
10.1158/1078-0432.CCR-15-1196
10.1016/j.bios.2017.11.028
10.1038/nrm3884
10.1101/cshperspect.a006676
10.1016/j.cell.2018.10.030
10.1016/j.addr.2018.08.005
10.1038/s41392-020-00323-3
10.1158/1078-0432.CCR-10-2268
10.1093/nar/gkz1176
10.1186/s11658-020-00221-0
10.1002/advs.202000925
10.1038/nbt.1633
10.1038/s41467-017-00902-z
10.1158/0008-5472.CAN-17-3454
10.1158/1078-0432.CCR-17-2967
10.1186/1471-2407-12-507
10.1016/j.soc.2007.08.004
10.1073/pnas.0904715106
10.1186/1756-9966-30-87
10.1016/j.molcel.2009.06.027
10.1126/science.aav0758
10.1038/sj.onc.1209846
10.1186/s12943-019-1063-6
10.1186/s12943-018-0860-7
10.1016/j.ymthe.2017.04.016
10.1016/j.molcel.2012.06.027
10.1016/j.omtn.2018.06.012
10.1016/j.ccell.2016.03.004
10.1016/j.molcel.2014.01.009
10.1038/s41590-018-0207-y
10.1371/journal.pone.0156274
10.1016/j.ccell.2015.02.004
10.1002/jcp.26568
10.1038/nm.3394
10.15252/embr.201847052
10.1038/s41419-020-2730-7
10.1016/0092-8674(92)90520-M
10.1038/s41418-020-0596-y
10.1038/cdd.2013.110
10.1021/bi0485732
10.1111/cas.13642
10.1016/j.molcel.2013.07.017
10.4149/neo_2014_075
10.1186/s12943-020-01206-5
10.1016/j.tplants.2017.03.009
10.1126/science.aad0467
10.1016/j.cell.2014.03.008
10.1158/0008-5472.CAN-17-1915
10.1038/s41556-019-0299-0
10.1186/s12943-020-01232-3
10.1007/s13402-019-00488-2
10.1016/j.bbagrm.2015.09.012
10.1038/s41392-020-0129-7
10.1242/dev.120.10.2933
10.1186/s12943-019-1047-6
10.1016/j.cell.2019.10.017
10.1002/cac2.12108
10.3389/fonc.2019.00739
10.1186/gb-2006-7-9-328
10.1172/JCI90327
10.1016/j.tcb.2017.10.001
10.1158/2159-8290.CD-15-0921
10.1016/j.ccell.2020.02.004
10.1038/onc.2015.340
10.1038/35077213
10.1186/s12943-020-1145-5
10.1186/s12943-019-1115-y
10.1186/s13045-019-0839-x
10.1101/gad.270959.115
10.1007/s10571-020-00898-z
10.1158/2326-6066.CIR-18-0108
10.1016/j.canlet.2016.07.015
10.1038/s41388-020-1158-y
10.1093/nass/48.1.7
10.1101/gad.17446611
10.1038/ncomms3939
10.1038/sj.onc.1206928
10.1038/cdd.2016.95
10.1158/0008-5472.CAN-19-0819
10.1002/cncr.28304
10.1093/bib/bbv031
10.1002/jcb.25987
10.1186/s12943-018-0884-z
10.1016/j.cell.2018.03.052
10.1038/ng.848
10.1038/nature17161
10.1186/1476-4598-13-92
10.1016/j.chembiol.2008.07.004
10.1038/onc.2015.18
10.1038/srep25776
10.1016/j.addr.2013.12.008
10.1016/0140-6736(93)91154-E
10.1158/0008-5472.CAN-16-0356
10.1002/hep.31280
10.1038/onc.2016.356
10.7150/ijms.27359
10.1038/s41586-020-1974-9
10.1158/0008-5472.CAN-18-2965
10.1080/01926230701320337
10.1016/j.molcel.2009.01.026
10.1016/j.cell.2018.03.064
10.1159/000443038
10.1091/mbc.e13-09-0558
10.1038/nrg3813
10.1158/1535-7163.MCT-14-0245
10.1038/nrm.2017.130
10.1016/j.celrep.2015.11.047
10.1186/s13046-018-0875-3
10.7150/thno.30372
10.1016/j.ccell.2016.03.010
10.1016/j.molcel.2013.08.011
10.1158/1078-0432.CCR-19-0747
10.1186/s12943-019-1014-2
10.1038/onc.2017.184
10.7150/thno.48698
10.1016/j.bbagrm.2014.08.012
10.1093/nar/gkw017
10.1038/s41467-019-09784-9
10.1016/j.cell.2010.06.040
10.18632/aging.103016
10.3389/fonc.2018.00327
10.1146/annurev-biochem-051410-092902
10.1002/hep.30102
10.1007/s13277-016-5125-8
10.1073/pnas.0807899106
10.1038/onc.2008.271
10.1016/j.chembiol.2016.05.021
10.1101/gad.276022.115
10.7150/thno.28992
10.1038/nrn849
10.1038/nbt.1560
10.1016/j.drup.2020.100683
10.1038/nsb1001-899
10.1038/nrm.2016.126
10.3389/fimmu.2014.00367
ContentType Journal Article
Copyright 2022 The Authors. published by John Wiley & Sons Australia, Ltd. on behalf of Sun Yat‐sen University Cancer Center
2022 The Authors. Cancer Communications published by John Wiley & Sons Australia, Ltd. on behalf of Sun Yat-sen University Cancer Center.
2022. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright_xml – notice: 2022 The Authors. published by John Wiley & Sons Australia, Ltd. on behalf of Sun Yat‐sen University Cancer Center
– notice: 2022 The Authors. Cancer Communications published by John Wiley & Sons Australia, Ltd. on behalf of Sun Yat-sen University Cancer Center.
– notice: 2022. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
DBID 24P
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
3V.
7RV
7X7
7XB
88E
8FI
8FJ
8FK
ABUWG
AFKRA
AZQEC
BENPR
CCPQU
DWQXO
FYUFA
GHDGH
K9-
K9.
KB0
M0R
M0S
M1P
NAPCQ
PHGZM
PHGZT
PIMPY
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
PRINS
7X8
5PM
DOA
DOI 10.1002/cac2.12254
DatabaseName Wiley Online Library Open Access
CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
ProQuest Central (Corporate)
Nursing & Allied Health Database
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central Essentials - QC
ProQuest Central
ProQuest One Community College
ProQuest Central
Health Research Premium Collection
Health Research Premium Collection (Alumni)
Consumer Health Database
ProQuest Health & Medical Complete (Alumni)
Nursing & Allied Health Database (Alumni Edition)
Consumer Health Database
ProQuest Health & Medical Collection
Medical Database
Nursing & Allied Health Premium
ProQuest Central Premium
ProQuest One Academic (New)
Publicly Available Content Database
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic (retired)
ProQuest One Academic UKI Edition
ProQuest Central China
MEDLINE - Academic
PubMed Central (Full Participant titles)
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
Publicly Available Content Database
ProQuest One Academic Middle East (New)
ProQuest Central Essentials
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Family Health (Alumni Edition)
ProQuest Central China
ProQuest Central
ProQuest Health & Medical Research Collection
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
Health & Medical Research Collection
ProQuest Central (New)
ProQuest Medical Library (Alumni)
ProQuest Family Health
ProQuest One Academic Eastern Edition
ProQuest Nursing & Allied Health Source
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
ProQuest Hospital Collection (Alumni)
Nursing & Allied Health Premium
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
ProQuest Nursing & Allied Health Source (Alumni)
ProQuest One Academic
ProQuest One Academic (New)
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList MEDLINE

Publicly Available Content Database

CrossRef
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: 24P
  name: Wiley Online Library Open Access (WRLC)
  url: https://authorservices.wiley.com/open-science/open-access/browse-journals.html
  sourceTypes: Publisher
– sequence: 3
  dbid: NPM
  name: PubMed
  url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 4
  dbid: 7RV
  name: Nursing & Allied Health Database
  url: https://search.proquest.com/nahs
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
DocumentTitleAlternate YAO et al
EISSN 2523-3548
EndPage 140
ExternalDocumentID oai_doaj_org_article_b9e88258bdb34f2cbdb72de0940edbe6
PMC8822594
35019235
10_1002_cac2_12254
CAC212254
Genre reviewArticle
Research Support, Non-U.S. Gov't
Journal Article
Review
GroupedDBID 0R~
1OC
24P
7RV
7X7
88E
8FI
8FJ
ABUWG
ACCMX
ACRMQ
ACXQS
ADKYN
ADPDF
ADUKV
ADZMN
ADZOD
AFKRA
AHSBF
ALMA_UNASSIGNED_HOLDINGS
ALUQN
AMKLP
AVUZU
AZQEC
BENPR
BMC
C24
C6C
CCPQU
EBS
EJD
FYUFA
GROUPED_DOAJ
HMCUK
HYE
IAO
IHR
IHW
ITC
K9-
M0R
M1P
M~E
NAPCQ
OK1
OVD
OVEED
PIMPY
PSQYO
ROL
RPM
RSV
SOJ
TEORI
UKHRP
WIN
AAYXX
AENVI
AFFHD
CITATION
PHGZM
PHGZT
PJZUB
PPXIY
CGR
CUY
CVF
ECM
EIF
NPM
3V.
7XB
8FK
DWQXO
K9.
PKEHL
PQEST
PQQKQ
PQUKI
PRINS
7X8
PUEGO
5PM
ID FETCH-LOGICAL-c5814-8672876c95596d8fde392fd8928b7017e7c7d192db34a27ec83f2149e50308e3
IEDL.DBID 7RV
ISICitedReferencesCount 219
ISICitedReferencesURI http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000741406600001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN 2523-3548
IngestDate Tue Oct 14 18:57:51 EDT 2025
Tue Nov 04 01:37:16 EST 2025
Thu Oct 02 11:45:23 EDT 2025
Tue Oct 07 07:05:44 EDT 2025
Wed Feb 19 02:26:42 EST 2025
Sat Nov 29 03:50:10 EST 2025
Tue Nov 18 22:31:06 EST 2025
Wed Jan 22 16:27:24 EST 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 2
Keywords RNA-binding protein
interaction network
treatment strategy
cancer
long non-coding RNA
cancer epigenetics
lncRNA-RBP
Language English
License Attribution-NonCommercial-NoDerivs
2022 The Authors. Cancer Communications published by John Wiley & Sons Australia, Ltd. on behalf of Sun Yat-sen University Cancer Center.
This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c5814-8672876c95596d8fde392fd8928b7017e7c7d192db34a27ec83f2149e50308e3
Notes These authors contributed equally to this work.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
ORCID 0000-0002-8979-610X
OpenAccessLink https://www.proquest.com/docview/2626182503?pq-origsite=%requestingapplication%
PMID 35019235
PQID 2626182503
PQPubID 2040150
PageCount 24
ParticipantIDs doaj_primary_oai_doaj_org_article_b9e88258bdb34f2cbdb72de0940edbe6
pubmedcentral_primary_oai_pubmedcentral_nih_gov_8822594
proquest_miscellaneous_2619216292
proquest_journals_2626182503
pubmed_primary_35019235
crossref_primary_10_1002_cac2_12254
crossref_citationtrail_10_1002_cac2_12254
wiley_primary_10_1002_cac2_12254_CAC212254
PublicationCentury 2000
PublicationDate February 2022
PublicationDateYYYYMMDD 2022-02-01
PublicationDate_xml – month: 02
  year: 2022
  text: February 2022
PublicationDecade 2020
PublicationPlace United States
PublicationPlace_xml – name: United States
– name: Hoboken
PublicationTitle Cancer communications (London, England)
PublicationTitleAlternate Cancer Commun (Lond)
PublicationYear 2022
Publisher John Wiley & Sons, Inc
John Wiley and Sons Inc
Wiley
Publisher_xml – name: John Wiley & Sons, Inc
– name: John Wiley and Sons Inc
– name: Wiley
References 2010; 12
2013; 4
2019; 10
2019; 16
2016; 30
2014; 25
2019; 18
2020; 13
2020; 12
2020; 11
2016; 380
2013; 5
2012; 12
2016; 38
2016; 37
2021; 73
2016; 35
2020; 19
2018; 46
2018; 175
2014; 1839
2018; 6
2018; 8
2013; 58
2018; 173
2019; 20
2013; 119
2010; 28
2019; 21
2013; 51
2017; 77
2016; 1859
2008; 27
2019; 25
2020; 578
2014; 15
2014; 13
2012; 22
2001; 411
2018; 37
2016; 44
2019; 8
2004; 43
2018; 28
2019; 9
2018; 102
2019; 37
2020; 39
2002; 2
2020; 37
2002; 3
2018; 109
2016; 17
1993; 341
2018; 25
2014; 157
2018; 24
2007; 16
2016; 11
2018; 19
2016; 5
2016; 6
2018; 17
2016; 7
2018; 233
2020; 27
2019; 179
2020; 25
2020; 24
2016; 29
2012; 47
2018; 12
2003; 22
2018; 14
2016; 23
2009; 106
2016; 22
1998; 8
2015; 34
2017; 8
2021; 28
2013; 20
2016; 76
2010; 142
2011; 17
2014; 61
2007; 35
2019; 365
2014; 66
2017; 118
2013; 19
2020; 7
2020; 5
2014; 5
2017; 36
2020; 50
2018; 134
2020; 48
2016; 352
2013; 152
2011; 25
2020; 43
2018; 78
2021; 41
2017; 127
2007; 26
2014; 53
2015; 13
2012; 81
2015; 14
2015; 6
2000; 157
2017; 25
2017; 22
2019; 79
2015; 11
2017; 24
2020; 80
2013; 41
2006; 7
2011; 30
2008; 15
2004
1992; 71
2009; 27
2018; 68
2009; 33
2009; 35
2012; 2
2015; 27
2021; 12
2014; 505
2021; 11
2017; 14
2016; 537
1994; 120
2001; 8
2016; 531
2011; 43
2020; 112
e_1_2_9_75_1
e_1_2_9_98_1
e_1_2_9_52_1
e_1_2_9_79_1
e_1_2_9_94_1
e_1_2_9_10_1
e_1_2_9_56_1
e_1_2_9_33_1
e_1_2_9_90_1
e_1_2_9_71_1
e_1_2_9_103_1
e_1_2_9_126_1
e_1_2_9_149_1
e_1_2_9_107_1
e_1_2_9_122_1
e_1_2_9_145_1
e_1_2_9_14_1
Işın M (e_1_2_9_130_1) 2015; 6
e_1_2_9_141_1
e_1_2_9_37_1
e_1_2_9_164_1
e_1_2_9_18_1
e_1_2_9_160_1
e_1_2_9_41_1
e_1_2_9_64_1
e_1_2_9_87_1
e_1_2_9_22_1
e_1_2_9_45_1
e_1_2_9_68_1
e_1_2_9_83_1
e_1_2_9_6_1
e_1_2_9_119_1
e_1_2_9_60_1
e_1_2_9_2_1
e_1_2_9_138_1
e_1_2_9_111_1
e_1_2_9_134_1
e_1_2_9_115_1
e_1_2_9_157_1
e_1_2_9_26_1
e_1_2_9_49_1
e_1_2_9_153_1
e_1_2_9_30_1
e_1_2_9_53_1
e_1_2_9_99_1
e_1_2_9_72_1
e_1_2_9_11_1
e_1_2_9_34_1
e_1_2_9_57_1
e_1_2_9_95_1
e_1_2_9_76_1
e_1_2_9_91_1
e_1_2_9_102_1
e_1_2_9_148_1
e_1_2_9_129_1
e_1_2_9_144_1
e_1_2_9_167_1
e_1_2_9_106_1
e_1_2_9_125_1
e_1_2_9_15_1
e_1_2_9_38_1
e_1_2_9_140_1
e_1_2_9_163_1
e_1_2_9_121_1
e_1_2_9_19_1
e_1_2_9_42_1
e_1_2_9_88_1
e_1_2_9_61_1
e_1_2_9_46_1
e_1_2_9_84_1
e_1_2_9_23_1
e_1_2_9_65_1
e_1_2_9_80_1
e_1_2_9_5_1
e_1_2_9_114_1
e_1_2_9_137_1
e_1_2_9_118_1
e_1_2_9_133_1
e_1_2_9_156_1
e_1_2_9_9_1
e_1_2_9_152_1
e_1_2_9_27_1
e_1_2_9_69_1
e_1_2_9_110_1
e_1_2_9_31_1
e_1_2_9_50_1
e_1_2_9_73_1
e_1_2_9_35_1
e_1_2_9_77_1
e_1_2_9_96_1
e_1_2_9_12_1
e_1_2_9_54_1
e_1_2_9_92_1
e_1_2_9_109_1
e_1_2_9_101_1
e_1_2_9_128_1
e_1_2_9_166_1
e_1_2_9_105_1
e_1_2_9_124_1
e_1_2_9_147_1
e_1_2_9_39_1
e_1_2_9_162_1
e_1_2_9_120_1
e_1_2_9_16_1
e_1_2_9_58_1
e_1_2_9_143_1
e_1_2_9_20_1
e_1_2_9_62_1
e_1_2_9_89_1
e_1_2_9_24_1
e_1_2_9_43_1
e_1_2_9_66_1
e_1_2_9_85_1
e_1_2_9_8_1
e_1_2_9_81_1
e_1_2_9_4_1
e_1_2_9_113_1
e_1_2_9_159_1
Smaldone MC (e_1_2_9_168_1) 2010; 12
e_1_2_9_117_1
e_1_2_9_155_1
e_1_2_9_136_1
e_1_2_9_151_1
e_1_2_9_28_1
e_1_2_9_47_1
e_1_2_9_132_1
e_1_2_9_74_1
e_1_2_9_51_1
e_1_2_9_78_1
e_1_2_9_13_1
e_1_2_9_32_1
e_1_2_9_55_1
e_1_2_9_97_1
e_1_2_9_93_1
e_1_2_9_108_1
e_1_2_9_70_1
e_1_2_9_127_1
e_1_2_9_100_1
e_1_2_9_123_1
e_1_2_9_104_1
e_1_2_9_146_1
e_1_2_9_17_1
e_1_2_9_36_1
e_1_2_9_59_1
e_1_2_9_142_1
e_1_2_9_165_1
e_1_2_9_161_1
e_1_2_9_63_1
e_1_2_9_40_1
e_1_2_9_21_1
e_1_2_9_67_1
e_1_2_9_44_1
e_1_2_9_86_1
e_1_2_9_7_1
e_1_2_9_82_1
e_1_2_9_3_1
e_1_2_9_112_1
e_1_2_9_139_1
e_1_2_9_116_1
e_1_2_9_135_1
e_1_2_9_158_1
e_1_2_9_25_1
e_1_2_9_131_1
e_1_2_9_154_1
e_1_2_9_48_1
e_1_2_9_29_1
e_1_2_9_150_1
References_xml – volume: 14
  start-page: 1960
  issue: 14
  year: 2018
  end-page: 73
  article-title: Exosomal Metastasis‑Associated Lung Adenocarcinoma Transcript 1 Promotes Angiogenesis and Predicts Poor Prognosis in Epithelial Ovarian Cancer
  publication-title: Int J Biol Sci
– volume: 34
  start-page: 5648
  issue: 45
  year: 2015
  end-page: 61
  article-title: SP1‐induced upregulation of the long noncoding RNA TINCR regulates cell proliferation and apoptosis by affecting KLF2 mRNA stability in gastric cancer
  publication-title: Oncogene
– volume: 15
  start-page: 749
  issue: 11
  year: 2014
  end-page: 60
  article-title: The structure, function and evolution of proteins that bind DNA and RNA
  publication-title: Nat Rev Mol Cell Biol
– volume: 35
  start-page: 2746
  issue: 21
  year: 2016
  end-page: 55
  article-title: LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer
  publication-title: Oncogene
– volume: 30
  start-page: 34
  issue: 1
  year: 2016
  end-page: 51
  article-title: Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss
  publication-title: Genes & development
– volume: 5
  start-page: 1143
  issue: 4
  year: 2013
  end-page: 6
  article-title: A long non‐coding RNA, PTCSC3, as a tumor suppressor and a target of miRNAs in thyroid cancer cells
  publication-title: Exp Ther Med
– volume: 33
  start-page: 717
  issue: 6
  year: 2009
  end-page: 26
  article-title: An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles
  publication-title: Mol Cell
– volume: 341
  start-page: 1251
  issue: 8855
  year: 1993
  end-page: 4
  article-title: Apoptosis and disease
  publication-title: Lancet
– volume: 106
  start-page: 11667
  issue: 28
  year: 2009
  end-page: 72
  article-title: Many human large intergenic noncoding RNAs associate with chromatin‐modifying complexes and affect gene expression
  publication-title: Proc Natl Acad Sci U S A.
– volume: 53
  start-page: 393
  issue: 3
  year: 2014
  end-page: 406
  article-title: Long noncoding RNA NEAT1‐dependent SFPQ relocation from promoter region to paraspeckle mediates IL8 expression upon immune stimuli
  publication-title: Mol Cell
– volume: 43
  start-page: 904
  issue: 6
  year: 2011
  end-page: 14
  article-title: Molecular mechanisms of long noncoding RNAs
  publication-title: Molecular cell
– volume: 12
  start-page: 684
  year: 2018
  end-page: 97
  article-title: A Novel lncRNA, LINC00460, Affects Cell Proliferation and Apoptosis by Regulating KLF2 and CUL4A Expression in Colorectal Cancer
  publication-title: Mol Ther Nucleic Acids
– volume: 41
  start-page: 1271
  issue: 6
  year: 2021
  end-page: 84
  article-title: LncRNA MIR155HG Promotes Temozolomide Resistance by Activating the Wnt/β‐Catenin Pathway Via Binding to PTBP1 in Glioma
  publication-title: Cell Mol Neurobiol
– volume: 8
  start-page: 73
  issue: 12
  year: 2019
  article-title: LncRNA MACC1‐AS1 sponges multiple miRNAs and RNA‐binding protein PTBP1
  publication-title: Oncogenesis
– volume: 46
  start-page: 5809
  issue: 11
  year: 2018
  end-page: 21
  article-title: Long noncoding RNA OCC‐1 suppresses cell growth through destabilizing HuR protein in colorectal cancer
  publication-title: Nucleic Acids Res
– volume: 175
  start-page: 1872
  issue: 7
  year: 2018
  end-page: 86
  article-title: Acetylation of cytidine in mRNA promotes translation efficiency
  publication-title: Cell
– volume: 18
  start-page: 187
  issue: 1
  year: 2019
  article-title: LINC02273 drives breast cancer metastasis by epigenetically increasing AGR2 transcription
  publication-title: Mol Cancer
– volume: 23
  start-page: 1077
  issue: 9
  year: 2016
  end-page: 90
  article-title: The Emerging Role of RNA as a Therapeutic Target for Small Molecules
  publication-title: Cell Chem Biol
– volume: 2
  start-page: 563
  issue: 8
  year: 2002
  end-page: 72
  article-title: Dissemination and growth of cancer cells in metastatic sites
  publication-title: Nat Rev Cancer
– volume: 112
  start-page: 356
  issue: 4
  year: 2020
  end-page: 68
  article-title: The Role of APAL/ST8SIA6‐AS1 lncRNA in PLK1 Activation and Mitotic Catastrophe of Tumor Cells
  publication-title: J Natl Cancer Inst
– volume: 13
  start-page: 2395
  issue: 11
  year: 2015
  end-page: 402
  article-title: Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis
  publication-title: Cell Rep
– volume: 19
  start-page: 2958
  issue: 10
  year: 2018
  article-title: Regulation of Macrophage Activation and Polarization by HCC‐Derived Exosomal lncRNA TUC339
  publication-title: Int J Mol Sci
– volume: 22
  start-page: 1775
  issue: 9
  year: 2012
  end-page: 89
  article-title: The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression
  publication-title: Genome Res
– volume: 41
  start-page: 109
  issue: 2
  year: 2021
  end-page: 20
  article-title: LncRNA‐mediated posttranslational modifications and reprogramming of energy metabolism in cancer
  publication-title: Cancer Commun (Lond)
– volume: 9
  start-page: 739
  year: 2019
  article-title: Long Non‐coding RNAs as Communicators and Mediators Between the Tumor Microenvironment and Cancer Cells
  publication-title: Front Oncol
– volume: 5
  start-page: 271
  issue: 1
  year: 2020
  article-title: Identification of miR‐515‐3p and its targets, vimentin and MMP3, as a key regulatory mechanism in esophageal cancer metastasis: functional and clinical significance
  publication-title: Signal Transduct Target Ther
– volume: 1859
  start-page: 192
  issue: 1
  year: 2016
  end-page: 9
  article-title: MALAT1 long non‐coding RNA in cancer
  publication-title: Biochim Biophys Acta
– volume: 15
  start-page: 829
  issue: 12
  year: 2014
  end-page: 45
  article-title: A census of human RNA‐binding proteins
  publication-title: Nat Rev Genet
– volume: 17
  start-page: 110
  issue: 1
  year: 2018
  article-title: The long non‐coding RNA CYTOR drives colorectal cancer progression by interacting with NCL and Sam68
  publication-title: Mol Cancer
– volume: 102
  start-page: 179
  year: 2018
  end-page: 88
  article-title: Nucleic acid aptamer‐based methods for diagnosis of infections
  publication-title: Biosens Bioelectron
– volume: 66
  start-page: 110
  year: 2014
  end-page: 6
  article-title: Lopez‐Berestein G. Liposomal siRNA nanocarriers for cancer therapy
  publication-title: Adv Drug Deliv Rev
– volume: 43
  start-page: 195
  issue: 2
  year: 2020
  end-page: 209
  article-title: Esophageal carcinoma: Towards targeted therapies
  publication-title: Cell Oncol (Dordr)
– volume: 25
  start-page: 6868
  issue: 22
  year: 2019
  end-page: 81
  article-title: Long Noncoding RNA SChLAP1 Forms a Growth‐Promoting Complex with HNRNPL in Human Glioblastoma through Stabilization of ACTN4 and Activation of NF‐κB Signaling
  publication-title: Clin Cancer Res
– volume: 11
  issue: 2
  year: 2015
  article-title: The roles of post‐translational modifications in the context of protein interaction networks
  publication-title: PLoS Comput Biol
– volume: 6
  year: 2016
  article-title: Evaluation of prostate cancer antigen 3 for detecting prostate cancer: a systematic review and meta‐analysis
  publication-title: Sci Rep
– volume: 36
  start-page: 5661
  issue: 41
  year: 2017
  end-page: 7
  article-title: LncRNA‐mediated regulation of cell signaling in cancer
  publication-title: Oncogene
– volume: 157
  start-page: 1415
  year: 2000
  end-page: 30
  article-title: Mechanisms of apoptosis
  publication-title: Am J Pathol
– volume: 17
  start-page: 3100
  issue: 10
  year: 2011
  end-page: 11
  article-title: B7‐h4 expression in human melanoma: its association with patients' survival and antitumor immune response
  publication-title: Clin Cancer Res
– volume: 8
  start-page: 2219
  issue: 16
  year: 1998
  end-page: 22
  article-title: The first analogues of LNA (locked nucleic acids): phosphorothioate‐LNA and 2′‐thio‐LNA
  publication-title: Bioorganic & Medicinal Chemistry Letters
– volume: 37
  start-page: 202
  issue: 1
  year: 2018
  article-title: SP1‐induced lncRNA AGAP2‐AS1 expression promotes chemoresistance of breast cancer by epigenetic regulation of MyD88
  publication-title: J Exp Clin Cancer Res
– volume: 77
  start-page: 6704
  issue: 23
  year: 2017
  end-page: 16
  article-title: Mesenchymal Stem Cells Promote Hepatocarcinogenesis via lncRNA‐MUF Interaction with ANXA2 and miR‐34a
  publication-title: Cancer Res
– volume: 28
  start-page: 503
  issue: 5
  year: 2010
  end-page: 10
  article-title: Ab initio reconstruction of cell type‐specific transcriptomes in mouse reveals the conserved multi‐exonic structure of lincRNAs
  publication-title: Nat Biotechnol
– volume: 12
  start-page: 6191
  issue: 7
  year: 2020
  end-page: 205
  article-title: Long non‐coding RNA TPT1‐AS1 promotes angiogenesis and metastasis of colorectal cancer through TPT1‐AS1/NF90/VEGFA signaling pathway
  publication-title: Aging (Albany NY)
– volume: 27
  start-page: 5904
  issue: 45
  year: 2008
  end-page: 12
  article-title: The tumor microenvironment and its role in promoting tumor growth
  publication-title: Oncogene
– volume: 22
  start-page: 1243
  issue: 5
  year: 2016
  end-page: 55
  article-title: Competitive Binding Between Id1 and E2F1 to Cdc20 Regulates E2F1 Degradation and Thymidylate Synthase Expression to Promote Esophageal Cancer Chemoresistance
  publication-title: Clin Cancer Res
– volume: 25
  start-page: 1980
  issue: 11
  year: 2018
  end-page: 95
  article-title: LncRNA CASC9 promotes esophageal squamous cell carcinoma metastasis through upregulating LAMC2 expression by interacting with the CREB‐binding protein
  publication-title: Cell Death Differ
– start-page: 7
  issue: 48
  year: 2004
  end-page: 8
  article-title: Synthesis and properties of a novel bridged nucleic acid analogue bearing a P3'→N5' phosphoroamidate linkage, 5'‐amino‐3', 5'‐BNA
  publication-title: Nucleic Acids Symp Ser (Oxf)
– volume: 27
  start-page: 370
  issue: 3
  year: 2015
  end-page: 81
  article-title: A cytoplasmic NF‐κB interacting long noncoding RNA blocks IκB phosphorylation and suppresses breast cancer metastasis
  publication-title: Cancer Cell
– volume: 13
  start-page: 1
  issue: 1
  year: 2020
  end-page: 20
  article-title: M6A‐mediated upregulation of LINC00958 increases lipogenesis and acts as a nanotherapeutic target in hepatocellular carcinoma
  publication-title: Journal of hematology & oncology
– volume: 16
  start-page: 51
  issue: 1
  year: 2019
  end-page: 9
  article-title: LncRNA SNHG6 promotes proliferation, invasion and migration in colorectal cancer cells by activating TGF‐β/Smad signaling pathway via targeting UPF1 and inducing EMT via regulation of ZEB1
  publication-title: Int J Med Sci
– volume: 6
  start-page: 1352
  issue: 11
  year: 2018
  end-page: 63
  article-title: Lnc‐C/EBPβ Negatively Regulates the Suppressive Function of Myeloid‐Derived Suppressor Cells
  publication-title: Cancer Immunol Res
– volume: 81
  start-page: 145
  year: 2012
  end-page: 66
  article-title: Genome regulation by long noncoding RNAs
  publication-title: Annu Rev Biochem
– volume: 25
  start-page: 1915
  issue: 18
  year: 2011
  end-page: 27
  article-title: Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
  publication-title: Genes Dev
– volume: 352
  start-page: 91
  issue: 6281
  year: 2016
  end-page: 5
  article-title: A long noncoding RNA associated with susceptibility to celiac disease
  publication-title: Science
– volume: 12
  start-page: 138
  issue: 2
  year: 2021
  article-title: LncRNA SNHG1 and RNA binding protein hnRNPL form a complex and coregulate CDH1 to boost the growth and metastasis of prostate cancer
  publication-title: Cell Death Dis
– volume: 9
  start-page: 1599
  issue: 6
  year: 2019
  end-page: 613
  article-title: Identification of miR‐29c and its Target FBXO31 as a Key Regulatory Mechanism in Esophageal Cancer Chemoresistance: Functional Validation and Clinical Significance
  publication-title: Theranostics
– volume: 5
  start-page: 3555
  issue: 12
  year: 2016
  end-page: 63
  article-title: Upregulation of LncRNA‐HIT promotes migration and invasion of non‐small cell lung cancer cells by association with ZEB1
  publication-title: Cancer Med
– volume: 15
  start-page: 644
  issue: 7
  year: 2008
  end-page: 5
  article-title: Bivalent aptamers deliver the punch
  publication-title: Chem Biol
– volume: 173
  start-page: 649
  issue: 3
  year: 2018
  end-page: 64
  article-title: An Integrated Genome‐wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance
  publication-title: Cell
– volume: 16
  start-page: 755
  issue: 4
  year: 2007
  end-page: 74
  article-title: Tumor microenvironment and immune escape
  publication-title: Surg Oncol Clin N Am
– volume: 14
  start-page: 268
  issue: 1
  year: 2015
  end-page: 77
  article-title: Long noncoding RNA ANRIL promotes non‐small cell lung cancer cell proliferation and inhibits apoptosis by silencing KLF2 and P21 expression
  publication-title: Mol Cancer Ther
– volume: 120
  start-page: 2933
  issue: 10
  year: 1994
  end-page: 43
  article-title: Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes
  publication-title: Development
– volume: 7
  issue: 16
  year: 2020
  article-title: Direct Targeting of CREB1 with Imperatorin Inhibits TGFβ2‐ERK Signaling to Suppress Esophageal Cancer Metastasis
  publication-title: Adv Sci (Weinh)
– volume: 531
  start-page: 518
  issue: 7595
  year: 2016
  end-page: 22
  article-title: Melanoma addiction to the long non‐coding RNA SAMMSON
  publication-title: Nature
– volume: 8
  start-page: 327
  year: 2018
  article-title: The Network of Non‐coding RNAs in Cancer Drug Resistance
  publication-title: Front Oncol
– volume: 127
  start-page: 1873
  issue: 5
  year: 2017
  end-page: 88
  article-title: Hepatocyte nuclear factor 1α suppresses steatosis‐associated liver cancer by inhibiting PPARγ transcription
  publication-title: J Clin Invest
– volume: 17
  start-page: 756
  issue: 12
  year: 2016
  end-page: 70
  article-title: Long non‐coding RNAs: spatial amplifiers that control nuclear structure and gene expression
  publication-title: Nat Rev Mol Cell Biol
– volume: 19
  start-page: 85
  issue: 1
  year: 2020
  article-title: LncRNA BCRT1 promotes breast cancer progression by targeting miR‐1303/PTBP3 axis
  publication-title: Mol Cancer
– volume: 12
  start-page: 607
  issue: 5
  year: 2010
  end-page: 16
  article-title: BC‐819, a plasmid comprising the H19 gene regulatory sequences and diphtheria toxin A, for the potential targeted therapy of cancers
  publication-title: Curr Opin Mol Ther
– volume: 119
  start-page: 3914
  issue: 22
  year: 2013
  end-page: 28
  article-title: Integration of cancer genomics with treatment selection: from the genome to predictive biomarkers
  publication-title: Cancer
– volume: 152
  start-page: 467
  issue: 3
  year: 2013
  end-page: 78
  article-title: Induction of Siglec‐G by RNA viruses inhibits the innate immune response by promoting RIG‐I degradation
  publication-title: Cell
– volume: 51
  start-page: 539
  issue: 4
  year: 2013
  end-page: 51
  article-title: The complexity of human ribosome biogenesis revealed by systematic nucleolar screening of Pre‐rRNA processing factors
  publication-title: Molecular cell
– volume: 8
  start-page: 783
  issue: 1
  year: 2017
  article-title: Energy stress‐induced lncRNA FILNC1 represses c‐Myc‐mediated energy metabolism and inhibits renal tumor development
  publication-title: Nat Commun
– volume: 29
  start-page: 452
  issue: 4
  year: 2016
  end-page: 63
  article-title: Long Noncoding RNAs in Cancer Pathways
  publication-title: Cancer Cell
– volume: 17
  start-page: 130
  issue: 1
  year: 2018
  article-title: The c‐Myc‐regulated lncRNA NEAT1 and paraspeckles modulate imatinib‐induced apoptosis in CML cells
  publication-title: Mol Cancer
– volume: 43
  start-page: 904
  issue: 6
  year: 2011
  end-page: 14
  article-title: Molecular mechanisms of long noncoding RNAs
  publication-title: Mol Cell
– volume: 47
  start-page: 648
  issue: 4
  year: 2012
  end-page: 55
  article-title: LincRNA‐p21 suppresses target mRNA translation
  publication-title: Mol Cell
– volume: 79
  start-page: 1285
  issue: 7
  year: 2019
  end-page: 92
  article-title: The Critical Role of RNA m6A Methylation in Cancer
  publication-title: Cancer Res
– volume: 19
  start-page: 115
  issue: 1
  year: 2020
  article-title: A novel LncRNA transcript, RBAT1, accelerates tumorigenesis through interacting with HNRNPL and cis‐activating E2F3
  publication-title: Mol Cancer
– volume: 19
  start-page: 1423
  issue: 11
  year: 2013
  end-page: 37
  article-title: Microenvironmental regulation of tumor progression and metastasis
  publication-title: Nat Med
– volume: 5
  start-page: 41
  issue: 1
  year: 2020
  article-title: Breast cancer‐derived exosomes transmit lncRNA SNHG16 to induce CD73+γδ1 Treg cells
  publication-title: Signal Transduct Target Ther
– volume: 26
  start-page: 851
  issue: 6
  year: 2007
  end-page: 8
  article-title: A large noncoding RNA is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas
  publication-title: Oncogene
– volume: 37
  start-page: 11623
  issue: 9
  year: 2016
  end-page: 31
  article-title: Role of long non‐coding RNA in tumor drug resistance
  publication-title: Tumour Biol
– volume: 61
  start-page: 379
  issue: 4
  year: 2014
  end-page: 91
  article-title: HOTAIR: a cancer‐related long non‐coding RNA
  publication-title: Neoplasma
– volume: 27
  start-page: 839
  issue: 9
  year: 2009
  end-page: 49
  article-title: Systemic administration of optimized aptamer‐siRNA chimeras promotes regression of PSMA‐expressing tumors
  publication-title: Nat Biotechnol
– volume: 380
  start-page: 476
  issue: 2
  year: 2016
  end-page: 84
  article-title: Long non‐coding RNA LINC01133 inhibits epithelial‐mesenchymal transition and metastasis in colorectal cancer by interacting with SRSF6
  publication-title: Cancer Lett
– volume: 109
  start-page: 2093
  issue: 7
  year: 2018
  end-page: 100
  article-title: Emerging roles of long non‐coding RNA in cancer
  publication-title: Cancer Sci
– volume: 29
  start-page: 653
  issue: 5
  year: 2016
  end-page: 68
  article-title: Exosome‐Transmitted lncARSR Promotes Sunitinib Resistance in Renal Cancer by Acting as a Competing Endogenous RNA
  publication-title: Cancer Cell
– volume: 35
  start-page: 467
  issue: 4
  year: 2009
  end-page: 78
  article-title: Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: functional role of a nuclear noncoding RNA
  publication-title: Mol Cell
– volume: 106
  start-page: 2525
  issue: 8
  year: 2009
  end-page: 30
  article-title: MENepsilon/beta noncoding RNAs are essential for structural integrity of nuclear paraspeckles
  publication-title: Proc Natl Acad Sci U S A.
– volume: 8
  start-page: 899
  issue: 10
  year: 2001
  end-page: 907
  article-title: Crystal structures of the catalytic domain of human protein kinase associated with apoptosis and tumor suppression
  publication-title: Nat Struct Biol
– volume: 11
  issue: 5
  year: 2016
  article-title: The lncRNA PVT1 Contributes to the Cervical Cancer Phenotype and Associates with Poor Patient Prognosis
  publication-title: PLoS One
– volume: 30
  start-page: 87
  issue: 1
  year: 2011
  article-title: Apoptosis in cancer: from pathogenesis to treatment
  publication-title: J Exp Clin Cancer Res
– volume: 157
  start-page: 77
  issue: 1
  year: 2014
  end-page: 94
  article-title: The noncoding RNA revolution‐trashing old rules to forge new ones
  publication-title: Cell
– volume: 18
  start-page: 1
  issue: 1
  year: 2019
  end-page: 16
  article-title: m6A‐induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1
  publication-title: Molecular cancer
– volume: 17
  start-page: 106
  issue: 1
  year: 2016
  end-page: 16
  article-title: Revealing protein‐lncRNA interaction
  publication-title: Brief Bioinform
– volume: 20
  issue: 8
  year: 2019
  article-title: The novel lncRNA CALIC upregulates AXL to promote colon cancer metastasis
  publication-title: EMBO Rep
– volume: 173
  start-page: 906
  issue: 4
  year: 2018
  end-page: 19
  article-title: Self‐Recognition of an Inducible Host lncRNA by RIG‐I Feedback Restricts Innate Immune Response
  publication-title: Cell
– volume: 51
  start-page: 349
  issue: 3
  year: 2013
  end-page: 59
  article-title: The long noncoding RNA RMST interacts with SOX2 to regulate neurogenesis
  publication-title: Mol Cell
– volume: 22
  start-page: 512
  issue: 6
  year: 2017
  end-page: 26
  article-title: RNA‐Binding Proteins Revisited ‐ The Emerging Arabidopsis mRNA Interactome
  publication-title: Trends Plant Sci
– volume: 24
  start-page: 7479
  issue: 13
  year: 2020
  end-page: 89
  article-title: Long non‐coding RNA SNGH7 Is activated by SP1 and exerts oncogenic properties by interacting with EZH2 in ovarian cancer
  publication-title: J Cell Mol Med
– volume: 76
  start-page: 6299
  issue: 21
  year: 2016
  end-page: 310
  article-title: LncRNA HOXA11‐AS Promotes Proliferation and Invasion of Gastric Cancer by Scaffolding the Chromatin Modification Factors PRC2, LSD1, and DNMT1
  publication-title: Cancer Res
– volume: 12
  start-page: 507
  year: 2012
  article-title: PCA3 noncoding RNA is involved in the control of prostate‐cancer cell survival and modulates androgen receptor signaling
  publication-title: BMC Cancer
– volume: 37
  start-page: 270
  issue: 3
  year: 2020
  end-page: 88
  article-title: m6A Modification in Coding and Non‐coding RNAs: Roles and Therapeutic Implications in Cancer
  publication-title: Cancer Cell
– volume: 6
  start-page: 784
  issue: 7
  year: 2016
  end-page: 801
  article-title: LncRNA GClnc1 Promotes Gastric Carcinogenesis and May Act as a Modular Scaffold of WDR5 and KAT2A Complexes to Specify the Histone Modification Pattern
  publication-title: Cancer Discov
– volume: 25
  start-page: 169
  issue: 1
  year: 2014
  end-page: 83
  article-title: NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies
  publication-title: Mol Biol Cell
– volume: 365
  issue: 6454
  year: 2019
  article-title: Nuclear hnRNPA2B1 initiates and amplifies the innate immune response to DNA viruses
  publication-title: Science
– volume: 48
  start-page: 2621
  issue: 5
  year: 2020
  end-page: 42
  article-title: The SINEB1 element in the long non‐coding RNA Malat1 is necessary for TDP‐43 proteostasis
  publication-title: Nucleic Acids Res
– volume: 25
  start-page: 1959
  issue: 8
  year: 2017
  end-page: 73
  article-title: lncRNA HOXD‐AS1 Regulates Proliferation and Chemo‐Resistance of Castration‐Resistant Prostate Cancer via Recruiting WDR5
  publication-title: Mol Ther
– volume: 28
  start-page: 219
  issue: 1
  year: 2021
  end-page: 32
  article-title: LINC00941 promotes CRC metastasis through preventing SMAD4 protein degradation and activating the TGF‐β/SMAD2/3 signaling pathway
  publication-title: Cell Death Differ
– volume: 30
  start-page: 1224
  issue: 10
  year: 2016
  end-page: 39
  article-title: HuR and GRSF1 modulate the nuclear export and mitochondrial localization of the lncRNA RMRP
  publication-title: Genes Dev
– volume: 3
  start-page: 453
  issue: 6
  year: 2002
  article-title: The stressed hippocampus, synaptic plasticity and lost memories
  publication-title: Nature Reviews Neuroscience
– volume: 37
  start-page: 270
  issue: 2
  year: 2019
  end-page: 83
  article-title: LncRNA‐OG Promotes the Osteogenic Differentiation of Bone Marrow‐Derived Mesenchymal Stem Cells Under the Regulation of hnRNPK
  publication-title: Stem Cells.
– volume: 537
  start-page: 369
  issue: 7620
  year: 2016
  end-page: 73
  article-title: m(6)A RNA methylation promotes XIST‐mediated transcriptional repression
  publication-title: Nature
– volume: 25
  start-page: 29
  year: 2020
  article-title: LncRNA DRAIC inhibits proliferation and metastasis of gastric cancer cells through interfering with NFRKB deubiquitination mediated by UCHL5
  publication-title: Cell Mol Biol Lett
– volume: 78
  start-page: 3484
  issue: 13
  year: 2018
  end-page: 96
  article-title: A G3BP1‐Interacting lncRNA Promotes Ferroptosis and Apoptosis in Cancer via Nuclear Sequestration of p53
  publication-title: Cancer Res
– volume: 9
  start-page: 796
  issue: 3
  year: 2019
  end-page: 810
  article-title: LINC01554‐Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway
  publication-title: Theranostics
– volume: 537
  start-page: 369
  issue: 7620
  year: 2016
  end-page: 73
  article-title: m(6)A RNA methylation promotes XIST‐mediated transcriptional repression
  publication-title: Nature.
– volume: 14
  start-page: 45
  issue: 1
  year: 2017
  end-page: 8
  article-title: A statistical test for conserved RNA structure shows lack of evidence for structure in lncRNAs
  publication-title: Nature methods
– volume: 11
  start-page: 1828
  issue: 4
  year: 2021
  end-page: 44
  article-title: Anti‐allergic drug azelastine suppresses colon tumorigenesis by directly targeting ARF1 to inhibit IQGAP1‐ERK‐Drp1‐mediated mitochondrial fission
  publication-title: Theranostics
– volume: 7
  issue: 5
  year: 2016
  article-title: Long intergenic non‐coding RNA APOC1P1‐3 inhibits apoptosis by decreasing α‐tubulin acetylation in breast cancer
  publication-title: Cell Death Dis
– volume: 80
  start-page: 2273
  issue: 11
  year: 2020
  end-page: 85
  article-title: Long Noncoding RNA MRPL23‐AS1 Promotes Adenoid Cystic Carcinoma Lung Metastasis
  publication-title: Cancer Res
– volume: 24
  start-page: 4808
  issue: 19
  year: 2018
  end-page: 19
  article-title: LncRNA‐FEZF1‐AS1 Promotes Tumor Proliferation and Metastasis in Colorectal Cancer by Regulating PKM2 Signaling
  publication-title: Clin Cancer Res
– volume: 28
  start-page: 113
  issue: 2
  year: 2018
  end-page: 27
  article-title: Reading m6A in the Transcriptome: m6A‐Binding Proteins
  publication-title: Trends Cell Biol
– volume: 50
  year: 2020
  article-title: Long non‐coding RNAs as a determinant of cancer drug resistance: Towards the overcoming of chemoresistance via modulation of lncRNAs
  publication-title: Drug Resist Updat
– volume: 2
  issue: 12
  year: 2012
  article-title: The role of the tumor microenvironment in regulating angiogenesis
  publication-title: Cold Spring Harb Perspect Med
– volume: 20
  start-page: 1558
  issue: 11
  year: 2013
  end-page: 68
  article-title: Negative regulation of lncRNA GAS5 by miR‐21
  publication-title: Cell Death Differ
– volume: 41
  start-page: 4976
  issue: 9
  year: 2013
  end-page: 87
  article-title: LncRNA loc285194 is a p53‐regulated tumor suppressor
  publication-title: Nucleic Acids Res
– volume: 7
  start-page: 328
  issue: 9
  year: 2006
  article-title: Regulatory RNAs and the demise of ‘junk’ DNA
  publication-title: Genome Biol
– volume: 22
  start-page: 8031
  issue: 39
  year: 2003
  end-page: 41
  article-title: MALAT‐1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early‐stage non‐small cell lung cancer
  publication-title: Oncogene
– volume: 411
  start-page: 342
  issue: 6835
  year: 2001
  end-page: 8
  article-title: Proliferation, cell cycle and apoptosis in cancer
  publication-title: Nature
– volume: 11
  start-page: 524
  issue: 7
  year: 2020
  article-title: Echinatin suppresses esophageal cancer tumor growth and invasion through inducing AKT/mTOR‐dependent autophagy and apoptosis
  publication-title: Cell Death Dis
– volume: 35
  start-page: 495
  issue: 4
  year: 2007
  end-page: 516
  article-title: Apoptosis: a review of programmed cell death
  publication-title: Toxicologic pathology
– volume: 118
  start-page: 3341
  issue: 10
  year: 2017
  end-page: 8
  article-title: LncRNA MALAT‐1 Elevates HMGB1 to Promote Autophagy Resulting in Inhibition of Tumor Cell Apoptosis in Multiple Myeloma
  publication-title: J Cell Biochem
– volume: 18
  start-page: 135
  issue: 1
  year: 2019
  article-title: LncRNA SATB2‐AS1 inhibits tumor metastasis and affects the tumor immune cell microenvironment in colorectal cancer by regulating SATB2
  publication-title: Mol Cancer
– volume: 13
  start-page: 3086
  issue: 12
  year: 2014
  end-page: 97
  article-title: Pseudogene PTENP1 functions as a competing endogenous RNA to suppress clear‐cell renal cell carcinoma progression
  publication-title: Mol Cancer Ther
– volume: 1839
  start-page: 1097
  issue: 11
  year: 2014
  end-page: 109
  article-title: LncRNA: a link between RNA and cancer
  publication-title: Biochim Biophys Acta
– volume: 39
  start-page: 2408
  issue: 11
  year: 2020
  end-page: 23
  article-title: Nur77‐activated lncRNA WFDC21P attenuates hepatocarcinogenesis via modulating glycolysis
  publication-title: Oncogene
– volume: 233
  start-page: 6518
  issue: 9
  year: 2018
  end-page: 23
  article-title: Long noncoding RNAs in cancer‐immunity cycle
  publication-title: J Cell Physiol
– volume: 36
  start-page: 1965
  issue: 14
  year: 2017
  end-page: 77
  article-title: Long noncoding RNA‐SRLR elicits intrinsic sorafenib resistance via evoking IL‐6/STAT3 axis in renal cell carcinoma
  publication-title: Oncogene
– volume: 21
  start-page: 498
  issue: 4
  year: 2019
  end-page: 510
  article-title: Extracellular vesicle‐packaged HIF‐1α‐stabilizing lncRNA from tumour‐associated macrophages regulates aerobic glycolysis of breast cancer cells
  publication-title: Nature cell biology
– volume: 27
  start-page: 1782
  issue: 6
  year: 2020
  end-page: 94
  article-title: IGF2BP2 regulates DANCR by serving as an N6‐methyladenosine reader
  publication-title: Cell Death & Differentiation
– volume: 19
  start-page: 26
  issue: 1
  year: 2020
  article-title: Exosome‐mediated lncRNA AFAP1‐AS1 promotes trastuzumab resistance through binding with AUF1 and activating ERBB2 translation
  publication-title: Mol Cancer
– volume: 24
  start-page: 59
  issue: 1
  year: 2017
  end-page: 71
  article-title: The degradation of EZH2 mediated by lncRNA ANCR attenuated the invasion and metastasis of breast cancer
  publication-title: Cell Death Differ
– volume: 13
  start-page: 209
  issue: 1
  year: 2015
  end-page: 21
  article-title: LncRNA HOTAIR Enhances the Androgen‐Receptor‐Mediated Transcriptional Program and Drives Castration‐Resistant Prostate Cancer
  publication-title: Cell Rep
– volume: 5
  start-page: 367
  year: 2014
  article-title: Toll‐Like Receptors and Cancer: MYD88 Mutation and Inflammation
  publication-title: Front Immunol
– volume: 19
  start-page: 1112
  issue: 10
  year: 2018
  end-page: 25
  article-title: NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation‐induced cell death
  publication-title: Nat Immunol
– volume: 73
  start-page: 644
  issue: 2
  year: 2021
  end-page: 60
  article-title: PPARγ Coactivator‐1α Suppresses Metastasis of Hepatocellular Carcinoma by Inhibiting Warburg Effect by PPARγ‐Dependent WNT/β‐Catenin/Pyruvate Dehydrogenase Kinase Isozyme 1 Axis
  publication-title: Hepatology
– volume: 10
  start-page: 2571
  issue: 1
  year: 2019
  article-title: LncRNA‐p21 alters the antiandrogen enzalutamide‐induced prostate cancer neuroendocrine differentiation via modulating the EZH2/STAT3 signaling
  publication-title: Nat Commun
– volume: 43
  start-page: 621
  issue: 7
  year: 2011
  end-page: 9
  article-title: Extensive and coordinated transcription of noncoding RNAs within cell‐cycle promoters
  publication-title: Nat Genet
– volume: 58
  start-page: 1703
  issue: 5
  year: 2013
  end-page: 12
  article-title: Posttranscriptional destabilization of the liver‐specific long noncoding RNA HULC by the IGF2 mRNA‐binding protein 1 (IGF2BP1)
  publication-title: Hepatology
– volume: 68
  start-page: 1817
  issue: 5
  year: 2018
  end-page: 32
  article-title: The Long Noncoding RNA Cancer Susceptibility 9 and RNA Binding Protein Heterogeneous Nuclear Ribonucleoprotein L Form a Complex and Coregulate Genes Linked to AKT Signaling
  publication-title: Hepatology
– volume: 505
  start-page: 117
  issue: 7481
  year: 2014
  end-page: 20
  article-title: N6‐methyladenosine‐dependent regulation of messenger RNA stability
  publication-title: Nature
– volume: 5
  start-page: 229
  issue: 1
  year: 2020
  article-title: Advances in targeted therapy for esophageal cancer
  publication-title: Signal Transduct Target Ther
– volume: 578
  start-page: 455
  issue: 7795
  year: 2020
  end-page: 60
  article-title: SPEN integrates transcriptional and epigenetic control of X‐inactivation
  publication-title: Nature
– volume: 179
  start-page: 1033
  issue: 5
  year: 2019
  end-page: 55
  article-title: The Role of Non‐coding RNAs in Oncology
  publication-title: Cell
– volume: 6
  start-page: 168
  year: 2015
  article-title: Exosomal lncRNA‐p21 levels may help to distinguish prostate cancer from benign disease
  publication-title: Front Genet
– volume: 43
  start-page: 13233
  issue: 42
  year: 2004
  end-page: 41
  article-title: LNA (locked nucleic acid): high‐affinity targeting of complementary RNA and DNA
  publication-title: Biochemistry
– volume: 38
  start-page: 836
  issue: 2
  year: 2016
  end-page: 46
  article-title: Upregulation of Long Non‐Coding RNA PlncRNA‐1 Promotes Metastasis and Induces Epithelial‐Mesenchymal Transition in Hepatocellular Carcinoma
  publication-title: Cell Physiol Biochem
– volume: 44
  start-page: 2378
  issue: 5
  year: 2016
  end-page: 92
  article-title: LncRNA OIP5‐AS1/cyrano sponges RNA‐binding protein HuR
  publication-title: Nucleic Acids Res
– volume: 13
  start-page: 92
  year: 2014
  article-title: Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR‐331‐3p in gastric cancer
  publication-title: Mol Cancer
– volume: 134
  start-page: 65
  year: 2018
  end-page: 78
  article-title: Aptamer‐based targeted therapy
  publication-title: Adv Drug Deliv Rev
– volume: 4
  start-page: 2939
  year: 2013
  article-title: Scaffold function of long non‐coding RNA HOTAIR in protein ubiquitination
  publication-title: Nat Commun
– volume: 71
  start-page: 527
  issue: 3
  year: 1992
  end-page: 42
  article-title: The human XIST gene: analysis of a 17 kb inactive X‐specific RNA that contains conserved repeats and is highly localized within the nucleus
  publication-title: Cell
– volume: 18
  start-page: 130
  issue: 1
  year: 2019
  article-title: Current perspectives on the immunosuppressive tumor microenvironment in hepatocellular carcinoma: challenges and opportunities
  publication-title: Mol Cancer
– volume: 19
  start-page: 327
  issue: 5
  year: 2018
  end-page: 41
  article-title: A brave new world of RNA‐binding proteins
  publication-title: Nat Rev Mol Cell Biol
– volume: 142
  start-page: 409
  issue: 3
  year: 2010
  end-page: 19
  article-title: A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response
  publication-title: Cell
– ident: e_1_2_9_78_1
  doi: 10.1093/nar/gky214
– ident: e_1_2_9_91_1
  doi: 10.1038/cddis.2016.142
– ident: e_1_2_9_35_1
  doi: 10.1371/journal.pcbi.1004049
– ident: e_1_2_9_157_1
  doi: 10.1016/j.molcel.2011.08.018
– ident: e_1_2_9_48_1
  doi: 10.1002/stem.2937
– ident: e_1_2_9_136_1
  doi: 10.3390/ijms19102958
– ident: e_1_2_9_65_1
  doi: 10.1038/nature12730
– ident: e_1_2_9_60_1
  doi: 10.1038/s41418-019-0461-z
– ident: e_1_2_9_103_1
  doi: 10.1002/cam4.948
– ident: e_1_2_9_68_1
  doi: 10.1038/nature19342
– ident: e_1_2_9_70_1
  doi: 10.1093/nar/gkt182
– ident: e_1_2_9_88_1
  doi: 10.1016/S0002-9440(10)64779-7
– ident: e_1_2_9_5_1
  doi: 10.1101/gr.132159.111
– ident: e_1_2_9_52_1
  doi: 10.1038/s41419-021-03413-4
– ident: e_1_2_9_63_1
  doi: 10.1038/s41389-019-0182-7
– volume: 12
  start-page: 607
  issue: 5
  year: 2010
  ident: e_1_2_9_168_1
  article-title: BC‐819, a plasmid comprising the H19 gene regulatory sequences and diphtheria toxin A, for the potential targeted therapy of cancers
  publication-title: Curr Opin Mol Ther
– ident: e_1_2_9_122_1
  doi: 10.1016/j.cell.2013.01.011
– ident: e_1_2_9_98_1
  doi: 10.1038/s41392-020-00275-8
– ident: e_1_2_9_84_1
  doi: 10.1158/1535-7163.MCT-14-0492
– ident: e_1_2_9_144_1
  doi: 10.7150/ijbs.28048
– ident: e_1_2_9_149_1
  doi: 10.1016/S0960-894X(98)00366-7
– ident: e_1_2_9_96_1
  doi: 10.1038/nrc865
– ident: e_1_2_9_101_1
  doi: 10.1111/jcmm.15373
– ident: e_1_2_9_155_1
  doi: 10.1038/nmeth.4066
– ident: e_1_2_9_61_1
  doi: 10.1038/s41418-018-0084-9
– ident: e_1_2_9_142_1
  doi: 10.3892/etm.2013.933
– ident: e_1_2_9_32_1
  doi: 10.1016/j.celrep.2015.08.069
– ident: e_1_2_9_62_1
  doi: 10.1002/hep.26537
– ident: e_1_2_9_33_1
  doi: 10.1093/jnci/djz134
– ident: e_1_2_9_111_1
  doi: 10.1158/1078-0432.CCR-15-1196
– ident: e_1_2_9_161_1
  doi: 10.1016/j.bios.2017.11.028
– ident: e_1_2_9_15_1
  doi: 10.1038/nrm3884
– ident: e_1_2_9_126_1
  doi: 10.1101/cshperspect.a006676
– ident: e_1_2_9_56_1
  doi: 10.1016/j.cell.2018.10.030
– ident: e_1_2_9_160_1
  doi: 10.1016/j.addr.2018.08.005
– ident: e_1_2_9_145_1
  doi: 10.1038/s41392-020-00323-3
– ident: e_1_2_9_51_1
  doi: 10.1158/1078-0432.CCR-10-2268
– ident: e_1_2_9_72_1
  doi: 10.1093/nar/gkz1176
– ident: e_1_2_9_74_1
  doi: 10.1186/s11658-020-00221-0
– ident: e_1_2_9_67_1
  doi: 10.1002/advs.202000925
– ident: e_1_2_9_3_1
  doi: 10.1038/nbt.1633
– ident: e_1_2_9_138_1
  doi: 10.1038/s41467-017-00902-z
– ident: e_1_2_9_93_1
  doi: 10.1158/0008-5472.CAN-17-3454
– ident: e_1_2_9_82_1
  doi: 10.1158/1078-0432.CCR-17-2967
– ident: e_1_2_9_166_1
  doi: 10.1186/1471-2407-12-507
– ident: e_1_2_9_124_1
  doi: 10.1016/j.soc.2007.08.004
– ident: e_1_2_9_26_1
  doi: 10.1073/pnas.0904715106
– ident: e_1_2_9_85_1
  doi: 10.1186/1756-9966-30-87
– ident: e_1_2_9_23_1
  doi: 10.1016/j.molcel.2009.06.027
– ident: e_1_2_9_50_1
  doi: 10.1126/science.aav0758
– ident: e_1_2_9_39_1
  doi: 10.1038/sj.onc.1209846
– ident: e_1_2_9_123_1
  doi: 10.1186/s12943-019-1063-6
– ident: e_1_2_9_83_1
  doi: 10.1186/s12943-018-0860-7
– ident: e_1_2_9_115_1
  doi: 10.1016/j.ymthe.2017.04.016
– ident: e_1_2_9_64_1
  doi: 10.1016/j.molcel.2012.06.027
– ident: e_1_2_9_66_1
  doi: 10.1016/j.omtn.2018.06.012
– ident: e_1_2_9_153_1
  doi: 10.1016/j.ccell.2016.03.004
– ident: e_1_2_9_25_1
  doi: 10.1016/j.molcel.2014.01.009
– ident: e_1_2_9_120_1
  doi: 10.1038/s41590-018-0207-y
– ident: e_1_2_9_152_1
  doi: 10.1371/journal.pone.0156274
– ident: e_1_2_9_41_1
  doi: 10.1016/j.ccell.2015.02.004
– ident: e_1_2_9_109_1
  doi: 10.1002/jcp.26568
– ident: e_1_2_9_127_1
  doi: 10.1038/nm.3394
– ident: e_1_2_9_100_1
  doi: 10.15252/embr.201847052
– ident: e_1_2_9_86_1
  doi: 10.1038/s41419-020-2730-7
– ident: e_1_2_9_8_1
  doi: 10.1016/0092-8674(92)90520-M
– ident: e_1_2_9_133_1
  doi: 10.1038/s41418-020-0596-y
– ident: e_1_2_9_141_1
  doi: 10.1038/cdd.2013.110
– ident: e_1_2_9_147_1
  doi: 10.1021/bi0485732
– ident: e_1_2_9_21_1
  doi: 10.1111/cas.13642
– ident: e_1_2_9_29_1
  doi: 10.1016/j.molcel.2013.07.017
– ident: e_1_2_9_158_1
  doi: 10.4149/neo_2014_075
– ident: e_1_2_9_131_1
  doi: 10.1186/s12943-020-01206-5
– ident: e_1_2_9_12_1
  doi: 10.1016/j.tplants.2017.03.009
– ident: e_1_2_9_49_1
  doi: 10.1126/science.aad0467
– ident: e_1_2_9_16_1
  doi: 10.1016/j.cell.2014.03.008
– ident: e_1_2_9_34_1
  doi: 10.1158/0008-5472.CAN-17-1915
– ident: e_1_2_9_55_1
  doi: 10.1038/s41556-019-0299-0
– ident: e_1_2_9_79_1
  doi: 10.1186/s12943-020-01232-3
– ident: e_1_2_9_146_1
  doi: 10.1007/s13402-019-00488-2
– ident: e_1_2_9_38_1
  doi: 10.1016/j.bbagrm.2015.09.012
– ident: e_1_2_9_129_1
  doi: 10.1038/s41392-020-0129-7
– ident: e_1_2_9_9_1
  doi: 10.1242/dev.120.10.2933
– ident: e_1_2_9_118_1
  doi: 10.1186/s12943-019-1047-6
– ident: e_1_2_9_6_1
  doi: 10.1016/j.cell.2019.10.017
– ident: e_1_2_9_11_1
  doi: 10.1002/cac2.12108
– ident: e_1_2_9_128_1
  doi: 10.3389/fonc.2019.00739
– ident: e_1_2_9_2_1
  doi: 10.1186/gb-2006-7-9-328
– ident: e_1_2_9_134_1
  doi: 10.1172/JCI90327
– ident: e_1_2_9_45_1
  doi: 10.1016/j.tcb.2017.10.001
– ident: e_1_2_9_27_1
  doi: 10.1158/2159-8290.CD-15-0921
– ident: e_1_2_9_44_1
  doi: 10.1016/j.ccell.2020.02.004
– ident: e_1_2_9_30_1
  doi: 10.1038/onc.2015.340
– ident: e_1_2_9_77_1
  doi: 10.1038/35077213
– ident: e_1_2_9_112_1
  doi: 10.1186/s12943-020-1145-5
– ident: e_1_2_9_99_1
  doi: 10.1186/s12943-019-1115-y
– ident: e_1_2_9_57_1
  doi: 10.1186/s13045-019-0839-x
– ident: e_1_2_9_59_1
  doi: 10.1038/nature19342
– ident: e_1_2_9_154_1
  doi: 10.1101/gad.270959.115
– ident: e_1_2_9_113_1
  doi: 10.1007/s10571-020-00898-z
– ident: e_1_2_9_119_1
  doi: 10.1158/2326-6066.CIR-18-0108
– ident: e_1_2_9_104_1
  doi: 10.1016/j.canlet.2016.07.015
– volume: 6
  start-page: 168
  year: 2015
  ident: e_1_2_9_130_1
  article-title: Exosomal lncRNA‐p21 levels may help to distinguish prostate cancer from benign disease
  publication-title: Front Genet
– ident: e_1_2_9_137_1
  doi: 10.1038/s41388-020-1158-y
– ident: e_1_2_9_150_1
  doi: 10.1093/nass/48.1.7
– ident: e_1_2_9_4_1
  doi: 10.1101/gad.17446611
– ident: e_1_2_9_43_1
  doi: 10.1038/ncomms3939
– ident: e_1_2_9_37_1
  doi: 10.1038/sj.onc.1206928
– ident: e_1_2_9_18_1
  doi: 10.1016/j.molcel.2011.08.018
– ident: e_1_2_9_42_1
  doi: 10.1038/cdd.2016.95
– ident: e_1_2_9_132_1
  doi: 10.1158/0008-5472.CAN-19-0819
– ident: e_1_2_9_143_1
  doi: 10.1002/cncr.28304
– ident: e_1_2_9_17_1
  doi: 10.1093/bib/bbv031
– ident: e_1_2_9_92_1
  doi: 10.1002/jcb.25987
– ident: e_1_2_9_95_1
  doi: 10.1186/s12943-018-0884-z
– ident: e_1_2_9_105_1
  doi: 10.1016/j.cell.2018.03.052
– ident: e_1_2_9_19_1
  doi: 10.1038/ng.848
– ident: e_1_2_9_151_1
  doi: 10.1038/nature17161
– ident: e_1_2_9_31_1
  doi: 10.1186/1476-4598-13-92
– ident: e_1_2_9_159_1
  doi: 10.1016/j.chembiol.2008.07.004
– ident: e_1_2_9_90_1
  doi: 10.1038/onc.2015.18
– ident: e_1_2_9_165_1
  doi: 10.1038/srep25776
– ident: e_1_2_9_163_1
  doi: 10.1016/j.addr.2013.12.008
– ident: e_1_2_9_89_1
  doi: 10.1016/0140-6736(93)91154-E
– ident: e_1_2_9_81_1
  doi: 10.1158/0008-5472.CAN-16-0356
– ident: e_1_2_9_135_1
  doi: 10.1002/hep.31280
– ident: e_1_2_9_114_1
  doi: 10.1038/onc.2016.356
– ident: e_1_2_9_73_1
  doi: 10.7150/ijms.27359
– ident: e_1_2_9_54_1
  doi: 10.1038/s41586-020-1974-9
– ident: e_1_2_9_46_1
  doi: 10.1158/0008-5472.CAN-18-2965
– ident: e_1_2_9_87_1
  doi: 10.1080/01926230701320337
– ident: e_1_2_9_24_1
  doi: 10.1016/j.molcel.2009.01.026
– ident: e_1_2_9_121_1
  doi: 10.1016/j.cell.2018.03.064
– ident: e_1_2_9_167_1
  doi: 10.1159/000443038
– ident: e_1_2_9_94_1
  doi: 10.1091/mbc.e13-09-0558
– ident: e_1_2_9_47_1
  doi: 10.1038/nrg3813
– ident: e_1_2_9_140_1
  doi: 10.1158/1535-7163.MCT-14-0245
– ident: e_1_2_9_13_1
  doi: 10.1038/nrm.2017.130
– ident: e_1_2_9_164_1
  doi: 10.1016/j.celrep.2015.11.047
– ident: e_1_2_9_117_1
  doi: 10.1186/s13046-018-0875-3
– ident: e_1_2_9_110_1
  doi: 10.7150/thno.30372
– ident: e_1_2_9_20_1
  doi: 10.1016/j.ccell.2016.03.010
– ident: e_1_2_9_53_1
  doi: 10.1016/j.molcel.2013.08.011
– ident: e_1_2_9_36_1
  doi: 10.1158/1078-0432.CCR-19-0747
– ident: e_1_2_9_58_1
  doi: 10.1186/s12943-019-1014-2
– ident: e_1_2_9_14_1
  doi: 10.1038/onc.2017.184
– ident: e_1_2_9_76_1
  doi: 10.7150/thno.48698
– ident: e_1_2_9_10_1
  doi: 10.1016/j.bbagrm.2014.08.012
– ident: e_1_2_9_28_1
  doi: 10.1093/nar/gkw017
– ident: e_1_2_9_40_1
  doi: 10.1038/s41467-019-09784-9
– ident: e_1_2_9_69_1
  doi: 10.1016/j.cell.2010.06.040
– ident: e_1_2_9_102_1
  doi: 10.18632/aging.103016
– ident: e_1_2_9_106_1
  doi: 10.3389/fonc.2018.00327
– ident: e_1_2_9_7_1
  doi: 10.1146/annurev-biochem-051410-092902
– ident: e_1_2_9_80_1
  doi: 10.1002/hep.30102
– ident: e_1_2_9_107_1
  doi: 10.1007/s13277-016-5125-8
– ident: e_1_2_9_22_1
  doi: 10.1073/pnas.0807899106
– ident: e_1_2_9_125_1
  doi: 10.1038/onc.2008.271
– ident: e_1_2_9_156_1
  doi: 10.1016/j.chembiol.2016.05.021
– ident: e_1_2_9_71_1
  doi: 10.1101/gad.276022.115
– ident: e_1_2_9_139_1
  doi: 10.7150/thno.28992
– ident: e_1_2_9_97_1
  doi: 10.1038/nrn849
– ident: e_1_2_9_162_1
  doi: 10.1038/nbt.1560
– ident: e_1_2_9_108_1
  doi: 10.1016/j.drup.2020.100683
– ident: e_1_2_9_148_1
  doi: 10.1038/nsb1001-899
– ident: e_1_2_9_75_1
  doi: 10.1038/nrm.2016.126
– ident: e_1_2_9_116_1
  doi: 10.3389/fimmu.2014.00367
SSID ssj0001989453
Score 2.5901532
SecondaryResourceType review_article
Snippet With the development of proteomics and epigenetics, a large number of RNA‐binding proteins (RBPs) have been discovered in recent years, and the interaction...
With the development of proteomics and epigenetics, a large number of RNA-binding proteins (RBPs) have been discovered in recent years, and the interaction...
Abstract With the development of proteomics and epigenetics, a large number of RNA‐binding proteins (RBPs) have been discovered in recent years, and the...
SourceID doaj
pubmedcentral
proquest
pubmed
crossref
wiley
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 117
SubjectTerms Binding sites
cancer
cancer epigenetics
Cell cycle
Cyclin-dependent kinases
Dehydrogenases
Epigenesis, Genetic
Epigenetics
Gene expression
Genomes
Growth factors
Humans
interaction network
Kinases
lncRNA‐RBP
long non‐coding RNA
Metastasis
MicroRNAs
Neoplasms - genetics
Neoplasms - metabolism
Prostate cancer
Proteins
Review
Reviews
RNA polymerase
RNA, Long Noncoding - genetics
RNA, Long Noncoding - metabolism
RNA-Binding Proteins - genetics
RNA-Binding Proteins - metabolism
RNA‐binding protein
Signal transduction
Stem cells
treatment strategy
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals
  dbid: DOA
  link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3NbtQwEB6hqgcuCFR-AgUZwQWk0NRxEue4rKg4rRDqoTcrHk9gpVW22myReusj8Iw8CTNOGu2KCi6cYtmONR6P42_i8WeAt6HNqDEZpj4rs9RoytPGEqZZXhiPdbAtDpdNVIuFvbiov-xc9SUxYQM98KC4E18Tg8DC-uBz02rkZ6UDCe0bBU-RbJtRz44zFf-uCK94kU98pPoEG9QfTtl6zd4KFIn670KXfwZJ7oLXuPqcPYQHI2xUs0HcR3CPuiNA_kKpZdeLf91zYrtWDOckQZvLVXOtxiAstVp33xT7-b9ufuJaFiv1dTHrVdMFSXCuX8bDLSqyNnCL3IZCsYfNYzg_-3Q-_5yOlyakWNhTk9qyYieoRGGWK1nVgRgBtcHW2vqKpx9VWAWGdaLORleENm81u0lUCHMN5U_ggOWhZ6CKJhDlLZXGBuOFWL5knZvaeH6t0JjAu1s9OhwJxeVei5UbqJC1E527qPME3kx1LwcajTtrfZThmGoI9XXMYINwo0G4fxlEAse3g-nG-dg7zX4be1LcxwReT8U8k2R7pOlofSV1hBuu1LVO4Okw9pMksv3KULhIoNqzij1R90u65ffI1s3CsovJfXsf7ecv3Xfz2VzH1PP_oYgXcF_LWY0YYn4MB9vNFb2EQ_yxXfabV3G-_AZgwh3E
  priority: 102
  providerName: Directory of Open Access Journals
– databaseName: Wiley Online Library Open Access
  dbid: 24P
  link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpZ3NbtQwEIBHpXDgwo_4CxRkBBeQQrOOkzgSl2VFxWlVoR56s2J7UlZaJVWyReLGI_CMPAkzTjbLigoJcYqVTBJPPBPPJPZngNe-TrBSiYttkiexkpjGlUYXJ2mmrCu9rt2w2ESxXOrz8_L0AN5v58IMfIjpgxt7Rnhfs4NXtj_eQUNd5eS7GZmjugE3Z7NU88INUp3uvrAwWzxgKCVlWzHdXE98Unm8O32vRwrg_uuizT8HTf4ezIbe6OTu_-lxD-6MUaiYD2ZzHw6weQCOXnhi1fScrvdU2LSCokMuYHe5rr6JcUyXWLfNhWja5uf3H67lvk98Xs57UTWeC7TXrsJcGREgEHRFuoZwbF7dQzg7-Xi2-BSPazDELtMzFeu8oJwqdwyqy6nlPFJAVXtdSm0L8mYsXOEpSvQ2VZUs0Om0lpR1YcYgHEwfwSHVB5-AyCqPmNaYK-2VZU59rhJUpbJ0WiZdBG-2zWDcyCfnZTLWZiArS8NPyoQnFcGrSfZyoHJcK_WBW3OSYJJ22NF2F2Z0TGNLpCQj05Y1qKWjbSE9MlYQvcU8gqOtLZjRvXsjKQ2kxIx0jODldJgck_-2VA22VyzDqLlcljKCx4PpTDXhv7kUWWcRFHtGtVfV_SPN6kuAf1NlKWMl3d4Go_qL-mYxX8hQevovws_gtuQpHmFk-hEcbrorfA633NfNqu9eBBf7Bf-0KZc
  priority: 102
  providerName: Wiley-Blackwell
Title New insights into the interplay between long non‐coding RNAs and RNA‐binding proteins in cancer
URI https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fcac2.12254
https://www.ncbi.nlm.nih.gov/pubmed/35019235
https://www.proquest.com/docview/2626182503
https://www.proquest.com/docview/2619216292
https://pubmed.ncbi.nlm.nih.gov/PMC8822594
https://doaj.org/article/b9e88258bdb34f2cbdb72de0940edbe6
Volume 42
WOSCitedRecordID wos000741406600001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVAON
  databaseName: DOAJ Directory of Open Access Journals
  customDbUrl:
  eissn: 2523-3548
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0001989453
  issn: 2523-3548
  databaseCode: DOA
  dateStart: 20180101
  isFulltext: true
  titleUrlDefault: https://www.doaj.org/
  providerName: Directory of Open Access Journals
– providerCode: PRVHPJ
  databaseName: ROAD: Directory of Open Access Scholarly Resources
  customDbUrl:
  eissn: 2523-3548
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0001989453
  issn: 2523-3548
  databaseCode: M~E
  dateStart: 20180101
  isFulltext: true
  titleUrlDefault: https://road.issn.org
  providerName: ISSN International Centre
– providerCode: PRVPQU
  databaseName: Health & Medical Collection
  customDbUrl:
  eissn: 2523-3548
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0001989453
  issn: 2523-3548
  databaseCode: 7X7
  dateStart: 20150101
  isFulltext: true
  titleUrlDefault: https://search.proquest.com/healthcomplete
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: Nursing & Allied Health Database
  customDbUrl:
  eissn: 2523-3548
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0001989453
  issn: 2523-3548
  databaseCode: 7RV
  dateStart: 20150101
  isFulltext: true
  titleUrlDefault: https://search.proquest.com/nahs
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: ProQuest Central
  customDbUrl:
  eissn: 2523-3548
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0001989453
  issn: 2523-3548
  databaseCode: BENPR
  dateStart: 20150101
  isFulltext: true
  titleUrlDefault: https://www.proquest.com/central
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: ProQuest Consumer Health Database
  customDbUrl:
  eissn: 2523-3548
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0001989453
  issn: 2523-3548
  databaseCode: M0R
  dateStart: 20150101
  isFulltext: true
  titleUrlDefault: https://search.proquest.com/familyhealth
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: Publicly Available Content Database
  customDbUrl:
  eissn: 2523-3548
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0001989453
  issn: 2523-3548
  databaseCode: PIMPY
  dateStart: 20150101
  isFulltext: true
  titleUrlDefault: http://search.proquest.com/publiccontent
  providerName: ProQuest
– providerCode: PRVWIB
  databaseName: Wiley Online Library Free Content
  customDbUrl:
  eissn: 2523-3548
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0001989453
  issn: 2523-3548
  databaseCode: WIN
  dateStart: 19970101
  isFulltext: true
  titleUrlDefault: https://onlinelibrary.wiley.com
  providerName: Wiley-Blackwell
– providerCode: PRVWIB
  databaseName: Wiley Online Library Open Access (WRLC)
  customDbUrl:
  eissn: 2523-3548
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0001989453
  issn: 2523-3548
  databaseCode: 24P
  dateStart: 19970101
  isFulltext: true
  titleUrlDefault: https://authorservices.wiley.com/open-science/open-access/browse-journals.html
  providerName: Wiley-Blackwell
link http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3NbtQwELZolwMXfsRfoKyM4AJSaNZxEueEtqtW9NAoWlWwnKLEnrQrrZIl2SJx4xF4Rp6EGSebsqLqhYszSRxrrJmxZ2znG8bemtKDXHraLbzQc6UA380VaNfzA1no2KhSd8kmoiRRi0Wc9gtubX-scjsm2oHa1JrWyA8Fet7oCwee_3H9zaWsUbS72qfQ2GOjCc3dqM_R_PP1Gguhiwf-gEoqDnWuxYcJ6rDcmYcsXP9NPua_RyX_dmHtHHTy4H-5f8ju994nn3bq8ojdgeox0zjQ8WXVUpjeIrGpOXqFRECzXuU_eH-Wi6_q6oJXdfX75y9d05zH58m05XlliMCnxdL-I8Mt-AO2iG1wTWrVPGHnJ8fns09un3vB1YGaSFeFEcZSoSaAuhAlZgAdqdKoWKgiQiuGSEcGvUNT-DIXEWjllwKjLQgIAAf8p2wf-YHnjAe5AfBLCKUysiB8-lB6IGNZ4GeB0A57txVEpntcckqPsco6RGWRkdAyKzSHvRnqrjs0jhtrHZE8hxqEoG0f1M1F1htkVsSAwUWgCupBKTReI2GA4ATBFBA67GAryaw36za7FqPDXg-v0SBplyWvoL6iOgQxF4pYOOxZpzwDJ7SLix514LBoR612WN19Uy0vLeg3MouRKvbtvVXAW7qfzaYzYakXt_fhJbsn6GcOewb9gO1vmit4xe7q75tl24zZnpDp2BoUlYvIlmrMRkfHSTof29ULLM88pEfp6Vn6Fe--nCZ_APgTMyY
linkProvider ProQuest
linkToHtml http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V3NbtQwELZKQYILP-IvUMAIOIAUmjpOnBwQWhaqVi0rhPawNyuxJ2WlVbIkW1BvPAIvwkvxJMw4P2VF1VsPnGIljjWTzIxn7PE3jD23RQCZDIyfB3HgSwGhnyVg_CCMZG5SmxSmLTahJpNkNks_bbBf_VkYSqvsbaIz1LYytEa-LdDzRl84CsK3y68-VY2i3dW-hEYrFgdw8h1DtubN_nv8vy-E2P0wHe_5XVUB30TJjvSTWGGUEBuCXouRFgvoIhQ2SUWSK5RPUEZZ9HtsHspMKDBJWAiMIyAiaBcIcdhL7DKacUUZZGqmTpd0CMw8CgcQVLFtMiNe76DKyLVpz1UHOMul_Tcz82-P2U15uzf-s491k13vfGs-apXhFtuA8jYzaMb5vGxoEaLBxqri6PNSA-rlIjvhXaYaX1TlES-r8vePn6aiGZ1_nowanpWWGng3n7sTQNxBW-CIOAY3pDT1HTa9CLbusk2kB-4zHmUWICwglomVOaHvxzIAmcocX4uE8djL_r9r06GuU_GPhW7xooUmGdFORjz2bOi7bLFGzuz1jsRn6EH44O5GVR_pztzoPAUMnaIkJw4KYfCqhAUCSwSbQ-yxrV5wdGe0Gn0qNR57OjxGc0N7SFkJ1TH1IQC9WKTCY_daWR0ooT1qjBcij6k1KV4jdf1JOf_iIM2RWIzDkbdXTt7PYV-PR2PhWg_O5-EJu7o3_XioD_cnBw_ZNUHHVly2_RbbXNXH8IhdMd9W86Z-7LSYM33BivAH9Y-DGw
linkToPdf http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpZ1fi9QwEMCDniK--Af_VU-N6ItCvW6aNunjurooyrLIPdxbaJLpubC0S7sn-OZH8DP6SZxJe10XD0F8aminbaaZaWba5BfGXvgqgVImLrZJnsRSQBqXGlycpJm0rvC6cv1iE2qx0CcnxXIYm0NzYXo-xPjBjTwjvK_JwWHjq6MdNdSVTryeoD3Ky-yKzNSEjFrI5e4TC8HFA4dSYLoV4931CCgVR7vT97qkQO6_KNz8c9Tk79Fs6I7mN_9TkVvsxhCH8mlvOLfZJajvMIevPL6qO0rYOyxsG47xIRWg3azLb3wY1cXXTX3K66b--f2Ha6j3458X046XtacC7rWrMFuGBwwEXhGvwR0ZWHuXHc_fHc_ex8MqDLHL9ETGOleYVeWOUHU5tp0HDKkqrwuhrUJ_BuWUxzjR21SWQoHTaSUw74KMUDiQ3mMHWB94wHhWeoC0glxqLy2R6nOZgCykxdMy4SL28rwdjBsI5bRQxtr0bGVh6EmZ8KQi9nyU3fRcjgul3lBzjhLE0g47mvbUDK5pbAGYZmTakgaVcLhVwgOBBcFbyCN2eG4MZnDwzghMBDE1Qx0j9mw8jK5J_1vKGpozkiHYXC4KEbH7ve2MNaH_uRhbZxFTe1a1V9X9I_XqS8B_Y2UxZ0XdXgWr-ov6ZjadiVB6-C_CT9m15du5-fRh8fERuy5ovkcYpn7IDrbtGTxmV93X7aprnwR3-wUYIS0G
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=New+insights+into+the+interplay+between+long+non%E2%80%90coding+RNAs+and+RNA%E2%80%90binding+proteins+in+cancer&rft.jtitle=Cancer+communications+%28London%2C+England%29&rft.au=Yao%2C+Zi%E2%80%90Ting&rft.au=Yang%2C+Yan%E2%80%90Ming&rft.au=Sun%2C+Miao%E2%80%90Miao&rft.au=He%2C+Yan&rft.date=2022-02-01&rft.pub=John+Wiley+and+Sons+Inc&rft.eissn=2523-3548&rft.volume=42&rft.issue=2&rft.spage=117&rft.epage=140&rft_id=info:doi/10.1002%2Fcac2.12254&rft_id=info%3Apmid%2F35019235&rft.externalDocID=PMC8822594
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2523-3548&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2523-3548&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2523-3548&client=summon