Plasma proteomic signature of the risk of developing mobility disability: A 9‐year follow‐up

Introduction Mobility disability is a powerful indicator of poor health in older adults. The biological and pathophysiological mechanism underlying the development of mobility disability remains unknown. This study conducted a data‐driven discovery phase investigation to identify plasma proteins tha...

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Bibliographic Details
Published in:	Aging cell Vol. 19; no. 4; pp. e13132 - n/a
Main Authors:	Osawa, Yusuke, Semba, Richard D., Fantoni, Giovanna, Candia, Julián, Biancotto, Angélique, Tanaka, Toshiko, Bandinelli, Stefania, Ferrucci, Luigi
Format:	Journal Article
Language:	English
Published:	England John Wiley & Sons, Inc 01.04.2020 John Wiley and Sons Inc
Subjects:	1-Phosphatidylinositol 3-kinase Aged Aged, 80 and over Aging AKT protein Biomarkers - blood Blood proteins Cathepsin S Cathepsins - blood Cytokines Disabled Persons - psychology Female Follow-Up Studies Growth Differentiation Factor 15 - blood growth/differentiation factor 15 Humans Middle Aged Mobility mobility disability Older people Original Phagosomes Plasma Plasma levels Plasma proteins Proteins Proteomics Risk Factors Senescence Thrombospondin Thrombospondins - blood thrombospondin‐2 Walking - psychology growth/differentiation factor 15 proteomics cathepsin S thrombospondin-2 mobility disability
ISSN:	1474-9718, 1474-9726, 1474-9726
Online Access:	Get full text
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