The Systems Biology Graphical Notation
A group of scientists in the systems biology community propose visual conventions for drawing biological diagrams. Circuit diagrams and Unified Modeling Language diagrams are just two examples of standard visual languages that help accelerate work by promoting regularity, removing ambiguity and enab...
Gespeichert in:
| Veröffentlicht in: | Nature biotechnology Jg. 27; H. 8; S. 735 - 741 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
New York
Nature Publishing Group US
01.08.2009
Nature Publishing Group |
| Schlagworte: | |
| ISSN: | 1087-0156, 1546-1696, 1546-1696 |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Abstract | A group of scientists in the systems biology community propose visual conventions for drawing biological diagrams.
Circuit diagrams and Unified Modeling Language diagrams are just two examples of standard visual languages that help accelerate work by promoting regularity, removing ambiguity and enabling software tool support for communication of complex information. Ironically, despite having one of the highest ratios of graphical to textual information, biology still lacks standard graphical notations. The recent deluge of biological knowledge makes addressing this deficit a pressing concern. Toward this goal, we present the Systems Biology Graphical Notation (SBGN), a visual language developed by a community of biochemists, modelers and computer scientists. SBGN consists of three complementary languages: process diagram, entity relationship diagram and activity flow diagram. Together they enable scientists to represent networks of biochemical interactions in a standard, unambiguous way. We believe that SBGN will foster efficient and accurate representation, visualization, storage, exchange and reuse of information on all kinds of biological knowledge, from gene regulation, to metabolism, to cellular signaling. |
|---|---|
| AbstractList | Circuit diagrams and Unified Modeling Language diagrams are just two examples of standard visual languages that help accelerate work by promoting regularity, removing ambiguity and enabling software tool support for communication of complex information. Ironically, despite having one of the highest ratios of graphical to textual information, biology still lacks standard graphical notations. The recent deluge of biological knowledge makes addressing this deficit a pressing concern. Toward this goal, we present the Systems Biology Graphical Notation (SBGN), a visual language developed by a community of biochemists, modelers and computer scientists. SBGN consists of three complementary languages: process diagram, entity relationship diagram and activity flow diagram. Together they enable scientists to represent networks of biochemical interactions in a standard, unambiguous way. We believe that SBGN will foster efficient and accurate representation, visualization, storage, exchange and reuse of information on all kinds of biological knowledge, from gene regulation, to metabolism, to cellular signaling. [PUBLICATION ABSTRACT] Circuit diagrams and Unified Modeling Language diagrams are just two examples of standard visual languages that help accelerate work by promoting regularity, removing ambiguity and enabling software tool support for communication of complex information. Ironically, despite having one of the highest ratios of graphical to textual information, biology still lacks standard graphical notations. The recent deluge of biological knowledge makes addressing this deficit a pressing concern. Toward this goal, we present the Systems Biology Graphical Notation (SBGN), a visual language developed by a community of biochemists, modelers and computer scientists. SBGN consists of three complementary languages: process diagram, entity relationship diagram and activity flow diagram. Together they enable scientists to represent networks of biochemical interactions in a standard, unambiguous way. We believe that SBGN will foster efficient and accurate representation, visualization, storage, exchange and reuse of information on all kinds of biological knowledge, from gene regulation, to metabolism, to cellular signaling. Circuit diagrams and Unified Modeling Language diagrams are just two examples of standard visual languages that help accelerate work by promoting regularity, removing ambiguity and enabling software tool support for communication of complex information. Ironically, despite having one of the highest ratios of graphical to textual information, biology still lacks standard graphical notations. The recent deluge of biological knowledge makes addressing this deficit a pressing concern. Toward this goal, we present the Systems Biology Graphical Notation (SBGN), a visual language developed by a community of biochemists, modelers and computer scientists. SBGN consists of three complementary languages: process diagram, entity relationship diagram and activity flow diagram. Together they enable scientists to represent networks of biochemical interactions in a standard, unambiguous way. We believe that SBGN will foster efficient and accurate representation, visualization, storage, exchange and reuse of information on all kinds of biological knowledge, from gene regulation, to metabolism, to cellular signaling.Circuit diagrams and Unified Modeling Language diagrams are just two examples of standard visual languages that help accelerate work by promoting regularity, removing ambiguity and enabling software tool support for communication of complex information. Ironically, despite having one of the highest ratios of graphical to textual information, biology still lacks standard graphical notations. The recent deluge of biological knowledge makes addressing this deficit a pressing concern. Toward this goal, we present the Systems Biology Graphical Notation (SBGN), a visual language developed by a community of biochemists, modelers and computer scientists. SBGN consists of three complementary languages: process diagram, entity relationship diagram and activity flow diagram. Together they enable scientists to represent networks of biochemical interactions in a standard, unambiguous way. We believe that SBGN will foster efficient and accurate representation, visualization, storage, exchange and reuse of information on all kinds of biological knowledge, from gene regulation, to metabolism, to cellular signaling. A group of scientists in the systems biology community propose visual conventions for drawing biological diagrams. Circuit diagrams and Unified Modeling Language diagrams are just two examples of standard visual languages that help accelerate work by promoting regularity, removing ambiguity and enabling software tool support for communication of complex information. Ironically, despite having one of the highest ratios of graphical to textual information, biology still lacks standard graphical notations. The recent deluge of biological knowledge makes addressing this deficit a pressing concern. Toward this goal, we present the Systems Biology Graphical Notation (SBGN), a visual language developed by a community of biochemists, modelers and computer scientists. SBGN consists of three complementary languages: process diagram, entity relationship diagram and activity flow diagram. Together they enable scientists to represent networks of biochemical interactions in a standard, unambiguous way. We believe that SBGN will foster efficient and accurate representation, visualization, storage, exchange and reuse of information on all kinds of biological knowledge, from gene regulation, to metabolism, to cellular signaling. |
| Audience | Academic |
| Author | Demir, Emek Ghosh, Samik Moodie, Stuart Bergman, Frank T Sander, Chris Matsuoka, Yukiko Wu, Guanming Funahashi, Akira Sahle, Sven Watterson, Steven Snoep, Jacky L Sorokin, Anatoly Schmidt, Esther Wegner, Katja Dogrusoz, Ugur Freeman, Tom C Kohn, Kurt Kitano, Hiroaki Villéger, Alice Kell, Douglas B Schreiber, Falk Aladjem, Mirit I Kolpakov, Fedor Sauro, Herbert Ghazal, Peter Luna, Augustin Courtot, Melanie Novère, Nicolas Le Goryanin, Igor Wimalaratne, Sarala M Jouraku, Akiya Li, Lu Calzone, Laurence Kim, Sohyoung Gauges, Ralph Kawaji, Hideya Boyd, Sarah E Hucka, Michael Mi, Huaiyu |
| Author_xml | – sequence: 1 givenname: Nicolas Le surname: Novère fullname: Novère, Nicolas Le email: lenov@ebi.ac.uk organization: EMBL European Bioinformatics Institute – sequence: 2 givenname: Michael surname: Hucka fullname: Hucka, Michael organization: Engineering and Applied Science, California Institute of Technology – sequence: 3 givenname: Huaiyu surname: Mi fullname: Mi, Huaiyu organization: SRI International – sequence: 4 givenname: Stuart surname: Moodie fullname: Moodie, Stuart organization: Centre for Systems Biology at Edinburgh, University of Edinburgh – sequence: 5 givenname: Falk surname: Schreiber fullname: Schreiber, Falk organization: Leibniz Institute of Plant Genetics and Crop Plant Research, Institute of Computer Science, University of Halle – sequence: 6 givenname: Anatoly surname: Sorokin fullname: Sorokin, Anatoly organization: School of Informatics, University of Edinburgh – sequence: 7 givenname: Emek surname: Demir fullname: Demir, Emek organization: Memorial Sloan Kettering Cancer Center - Computational Biology Center – sequence: 8 givenname: Katja surname: Wegner fullname: Wegner, Katja organization: Science and Technology Research Institute, University of Hertfordshire – sequence: 9 givenname: Mirit I surname: Aladjem fullname: Aladjem, Mirit I organization: National Cancer Institute – sequence: 10 givenname: Sarala M surname: Wimalaratne fullname: Wimalaratne, Sarala M organization: Auckland Bioengineering Institute, University of Auckland – sequence: 11 givenname: Frank T surname: Bergman fullname: Bergman, Frank T organization: Department of Bioengineering, University of Washington – sequence: 12 givenname: Ralph surname: Gauges fullname: Gauges, Ralph organization: BIOQUANT, University of Heidelberg – sequence: 13 givenname: Peter surname: Ghazal fullname: Ghazal, Peter organization: Centre for Systems Biology at Edinburgh, University of Edinburgh, Division of Pathway Medicine, University of Edinburgh Medical School – sequence: 14 givenname: Hideya surname: Kawaji fullname: Kawaji, Hideya organization: Riken OMICS Science Center – sequence: 15 givenname: Lu surname: Li fullname: Li, Lu organization: EMBL European Bioinformatics Institute – sequence: 16 givenname: Yukiko surname: Matsuoka fullname: Matsuoka, Yukiko organization: The Systems Biology Institute – sequence: 17 givenname: Alice surname: Villéger fullname: Villéger, Alice organization: School of Computer Science, University of Manchester, Manchester Interdisciplinary Biocentre – sequence: 18 givenname: Sarah E surname: Boyd fullname: Boyd, Sarah E organization: Clayton School of Information Technology, Faculty of Information Technology, Monash University – sequence: 19 givenname: Laurence surname: Calzone fullname: Calzone, Laurence organization: U900 INSERM, Paris Mines Tech, Institut Curie – sequence: 20 givenname: Melanie surname: Courtot fullname: Courtot, Melanie organization: Terry Fox Laboratory, British Columbia Cancer Research Center – sequence: 21 givenname: Ugur surname: Dogrusoz fullname: Dogrusoz, Ugur organization: Bilkent Center for Bioinformatics, Bilkent University – sequence: 22 givenname: Tom C surname: Freeman fullname: Freeman, Tom C organization: Division of Pathway Medicine, University of Edinburgh Medical School, The Roslin Institute, University of Edinburgh – sequence: 23 givenname: Akira surname: Funahashi fullname: Funahashi, Akira organization: Department of Biosciences and Informatics, Keio University, Hiyoshi – sequence: 24 givenname: Samik surname: Ghosh fullname: Ghosh, Samik organization: The Systems Biology Institute – sequence: 25 givenname: Akiya surname: Jouraku fullname: Jouraku, Akiya organization: Department of Biosciences and Informatics, Keio University, Hiyoshi – sequence: 26 givenname: Sohyoung surname: Kim fullname: Kim, Sohyoung organization: National Cancer Institute – sequence: 27 givenname: Fedor surname: Kolpakov fullname: Kolpakov, Fedor organization: Institute of Systems Biology, Design Technological Institute of Digital Techniques SB RAS – sequence: 28 givenname: Augustin surname: Luna fullname: Luna, Augustin organization: National Cancer Institute – sequence: 29 givenname: Sven surname: Sahle fullname: Sahle, Sven organization: BIOQUANT, University of Heidelberg – sequence: 30 givenname: Esther surname: Schmidt fullname: Schmidt, Esther organization: EMBL European Bioinformatics Institute – sequence: 31 givenname: Steven surname: Watterson fullname: Watterson, Steven organization: Centre for Systems Biology at Edinburgh, University of Edinburgh, Bilkent Center for Bioinformatics, Bilkent University – sequence: 32 givenname: Guanming surname: Wu fullname: Wu, Guanming organization: Ontario Institute for Cancer Research – sequence: 33 givenname: Igor surname: Goryanin fullname: Goryanin, Igor organization: Centre for Systems Biology at Edinburgh, University of Edinburgh – sequence: 34 givenname: Douglas B surname: Kell fullname: Kell, Douglas B organization: Manchester Interdisciplinary Biocentre, School of Chemistry, University of Manchester – sequence: 35 givenname: Chris surname: Sander fullname: Sander, Chris organization: Memorial Sloan Kettering Cancer Center - Computational Biology Center – sequence: 36 givenname: Herbert surname: Sauro fullname: Sauro, Herbert organization: Department of Bioengineering, University of Washington – sequence: 37 givenname: Jacky L surname: Snoep fullname: Snoep, Jacky L organization: Department of Biochemistry, Stellenbosch University – sequence: 38 givenname: Kurt surname: Kohn fullname: Kohn, Kurt organization: National Cancer Institute – sequence: 39 givenname: Hiroaki surname: Kitano fullname: Kitano, Hiroaki organization: The Systems Biology Institute, Sony Computer Science Laboratories, Okinawa Institute of Science and Technology |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/19668183$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNkm1rFDEUhYNU7IuCv0AWhargrHmZZDIfa9FaKBZs9WvIZO7Mpswk2yQD7r83y67WbUUkcBPCc244N-cQ7TnvAKHnBM8JZvK9a9KccC4foQPCS1EQUYu9fMayKjDhYh8dxniDMRalEE_QPqmFkESyA3R8vYDZ1SomGOPsg_WD71ezs6CXC2v0MPvik07Wu6focaeHCM-2-xH69unj9enn4uLy7Pz05KIwXOJUtBiqrmGUSNPWHNpONBra_GbNu9aURmgKpAQwVU1ESwXBgAUmWubaMEzYEXq96bsM_naCmNRoo4Fh0A78FFXFWC2qErNMHv-TpIRSzOkafHkPvPFTcNmFopQyXFW1zNCrDdTrAZR1nU9Bm3VHdUKx4KwUJc3U_C9UXi2M1uQv6Wy-3xG83RFkJsGP1OspRnV-9fX_2cvvu-y7P9hmitZBzCXafpHiRrKDv9iOYGpGaNUy2FGHlfoVgztjJvgYA3TK2M3HZ4N2UASrdc5Uzpla5ywL3twT_O75EN36ihlxPYS7-T9gfwKN9dnZ |
| CitedBy_id | crossref_primary_10_3390_cancers12040990 crossref_primary_10_1016_j_dche_2024_100210 crossref_primary_10_1038_clpt_2013_242 crossref_primary_10_1038_oncsis_2015_19 crossref_primary_10_3389_fmicb_2020_00028 crossref_primary_10_1371_journal_ppat_1003804 crossref_primary_10_3390_math10071176 crossref_primary_10_1517_17460440903548226 crossref_primary_10_1038_ncomms7319 crossref_primary_10_1093_nar_gkv1024 crossref_primary_10_1371_journal_pcbi_1013128 crossref_primary_10_1186_s12859_014_0369_z crossref_primary_10_1186_s12859_014_0420_0 crossref_primary_10_1186_s12859_021_04541_6 crossref_primary_10_3389_fphys_2021_746300 crossref_primary_10_1111_febs_17221 crossref_primary_10_1093_bib_bbaa390 crossref_primary_10_3390_jpm12020166 crossref_primary_10_1016_j_jsbmb_2016_04_015 crossref_primary_10_3389_fmolb_2021_754444 crossref_primary_10_1093_bib_bbac212 crossref_primary_10_3390_ijms252111782 crossref_primary_10_1038_ncomms6005 crossref_primary_10_1093_bib_bbaa152 crossref_primary_10_1093_bib_bbaa392 crossref_primary_10_1371_journal_pcbi_1005857 crossref_primary_10_1017_S0269888916000011 crossref_primary_10_1093_glycob_cwr036 crossref_primary_10_3390_app13106149 crossref_primary_10_1371_journal_pcbi_1005740 crossref_primary_10_1016_j_bej_2016_01_013 crossref_primary_10_1038_nbt_1567 crossref_primary_10_1038_nmeth_1436 crossref_primary_10_1038_nchembio_574 crossref_primary_10_1109_TCBB_2019_2938501 crossref_primary_10_1145_2633461 crossref_primary_10_1016_j_clim_2023_109839 crossref_primary_10_1371_journal_pone_0051000 crossref_primary_10_1038_nbt_2891 crossref_primary_10_1038_s41514_019_0039_5 crossref_primary_10_1104_pp_109_149237 crossref_primary_10_1186_s12859_015_0863_y crossref_primary_10_1002_cite_201200234 crossref_primary_10_1182_blood_2009_08_215798 crossref_primary_10_1186_1752_0509_4_65 crossref_primary_10_1016_j_biosystems_2023_105001 crossref_primary_10_1002_psp4_12225 crossref_primary_10_1016_j_toxlet_2022_07_459 crossref_primary_10_1186_1752_0509_4_63 crossref_primary_10_1109_TCBB_2018_2805686 crossref_primary_10_3390_bioengineering8080114 crossref_primary_10_1016_j_bbrc_2012_06_085 crossref_primary_10_1038_npjsba_2015_7 crossref_primary_10_1109_TVCG_2012_271 crossref_primary_10_1371_journal_pbio_1002310 crossref_primary_10_1007_s12253_018_0467_8 crossref_primary_10_1093_bib_bbp054 crossref_primary_10_1111_cgf_13072 crossref_primary_10_1371_journal_pone_0029406 crossref_primary_10_1186_s12859_021_04477_x crossref_primary_10_1093_nar_gkz440 crossref_primary_10_1016_j_biochi_2012_05_024 crossref_primary_10_3389_ftox_2025_1619651 crossref_primary_10_3390_biology9100314 crossref_primary_10_1186_1471_2105_13_S8_S3 crossref_primary_10_7554_eLife_04640 crossref_primary_10_1145_2668126 crossref_primary_10_1002_pro_4218 crossref_primary_10_3389_fphys_2015_00383 crossref_primary_10_1016_j_chembiol_2013_03_018 crossref_primary_10_1016_j_bcp_2013_03_021 crossref_primary_10_3390_ijms232012560 crossref_primary_10_1111_brv_12407 crossref_primary_10_1093_bib_bby099 crossref_primary_10_1093_bib_bbz067 crossref_primary_10_1016_j_molcel_2017_09_024 crossref_primary_10_7554_eLife_73031 crossref_primary_10_1016_j_copbio_2023_102922 crossref_primary_10_1038_nbt0909_864d crossref_primary_10_1002_psp4_12381 crossref_primary_10_1016_j_biochi_2019_04_024 crossref_primary_10_7554_eLife_68292 crossref_primary_10_3390_cancers12123600 crossref_primary_10_1371_journal_pcbi_1010086 crossref_primary_10_1186_s12859_016_1394_x crossref_primary_10_1002_bmb_21448 crossref_primary_10_1016_j_coisb_2021_100362 crossref_primary_10_1183_09031936_00078812 crossref_primary_10_1093_bib_bbab103 crossref_primary_10_1104_pp_113_224394 crossref_primary_10_1038_ncomms13254 crossref_primary_10_1186_1752_0509_6_130 crossref_primary_10_1016_j_future_2015_04_012 crossref_primary_10_1371_journal_pcbi_1012374 crossref_primary_10_1371_journal_pcbi_1004989 crossref_primary_10_1093_bioinformatics_btab432 crossref_primary_10_1187_cbe_20_04_0078 crossref_primary_10_1111_febs_15059 crossref_primary_10_1038_s41540_021_00182_w crossref_primary_10_1038_nbt_1666 crossref_primary_10_3389_fsysb_2025_1504077 crossref_primary_10_1186_s40708_023_00208_5 crossref_primary_10_1371_journal_pone_0156844 crossref_primary_10_1109_ACCESS_2021_3093524 crossref_primary_10_1371_journal_pone_0076143 crossref_primary_10_3389_fbioe_2019_00040 crossref_primary_10_3389_fendo_2016_00061 crossref_primary_10_1007_s12021_022_09584_5 crossref_primary_10_1002_cne_23348 crossref_primary_10_1155_2010_268925 crossref_primary_10_1016_j_biotechadv_2011_07_010 crossref_primary_10_1093_femsyr_foae011 crossref_primary_10_1038_msb_2011_77 crossref_primary_10_1016_j_yebeh_2013_08_029 crossref_primary_10_1109_TBME_2016_2560762 crossref_primary_10_1016_j_jbi_2025_104804 crossref_primary_10_1186_s12918_018_0579_5 crossref_primary_10_1186_1471_2105_14_250 crossref_primary_10_1093_nar_gkp1019 crossref_primary_10_1007_s43032_020_00187_6 crossref_primary_10_1093_nar_gkq499 crossref_primary_10_1186_1752_0509_6_52 crossref_primary_10_1016_j_fob_2015_03_002 crossref_primary_10_1093_nar_gkad1025 crossref_primary_10_3233_AO_160167 crossref_primary_10_1002_bdd_1875 crossref_primary_10_1186_1752_0509_7_58 crossref_primary_10_1109_TCBB_2019_2937033 crossref_primary_10_1016_j_freeradbiomed_2012_04_034 crossref_primary_10_1016_j_neuint_2012_11_015 crossref_primary_10_1109_TMSCS_2015_2478442 crossref_primary_10_1016_j_jtbi_2012_09_019 crossref_primary_10_1038_s41597_025_05147_w crossref_primary_10_15252_msb_20198955 crossref_primary_10_1016_j_tibtech_2012_08_003 crossref_primary_10_1371_journal_pone_0281401 crossref_primary_10_1145_3453681 crossref_primary_10_1261_rna_055749_115 crossref_primary_10_1007_s12035_013_8489_4 crossref_primary_10_1016_j_jbiotec_2014_03_029 crossref_primary_10_1093_bib_bbw090 crossref_primary_10_1155_2011_930940 crossref_primary_10_1002_psp4_12071 crossref_primary_10_1186_s12918_017_0431_3 crossref_primary_10_7554_eLife_34595 crossref_primary_10_1093_nar_gkx1132 crossref_primary_10_3390_metabo10020066 crossref_primary_10_1186_s12918_015_0187_6 crossref_primary_10_1038_s41540_024_00450_5 crossref_primary_10_15252_msb_202110387 crossref_primary_10_1093_nar_gks657 crossref_primary_10_1186_1752_0509_4_164 crossref_primary_10_1371_journal_pcbi_1004941 crossref_primary_10_1093_nar_gkq352 crossref_primary_10_1007_s00726_011_1035_7 crossref_primary_10_1186_1471_2105_12_167 crossref_primary_10_32604_biocell_2021_014756 crossref_primary_10_1186_s12859_021_04158_9 crossref_primary_10_1093_nar_gkad1041 crossref_primary_10_1371_journal_pone_0087397 crossref_primary_10_1177_1177625017691937 crossref_primary_10_1093_bib_bby025 crossref_primary_10_1093_bib_bby024 crossref_primary_10_1074_jbc_M110_113860 crossref_primary_10_1371_journal_pone_0014791 crossref_primary_10_1038_s41467_019_08903_w crossref_primary_10_1155_2013_320715 crossref_primary_10_3390_cancers13010035 crossref_primary_10_3389_fimmu_2023_1233680 crossref_primary_10_1186_s13040_021_00279_2 crossref_primary_10_1016_j_bpc_2015_06_010 crossref_primary_10_1186_1471_2164_13_S5_S3 crossref_primary_10_1038_srep42135 crossref_primary_10_12688_f1000research_13197_1 crossref_primary_10_1093_bib_bbx163 crossref_primary_10_1186_s12859_024_05782_x crossref_primary_10_1038_s41598_017_12538_6 crossref_primary_10_1186_1752_0509_6_11 crossref_primary_10_12688_f1000research_13197_2 crossref_primary_10_1111_j_1742_4658_2012_08665_x crossref_primary_10_1371_journal_pone_0263057 crossref_primary_10_3389_fimmu_2025_1601670 crossref_primary_10_1016_j_biosystems_2015_03_003 crossref_primary_10_3389_fbioe_2020_00942 crossref_primary_10_1038_s41540_025_00496_z crossref_primary_10_1002_bit_27943 crossref_primary_10_1038_nrg3885 crossref_primary_10_1371_journal_pcbi_1009227 crossref_primary_10_1038_msb_2012_12 crossref_primary_10_1038_msb_2010_73 crossref_primary_10_1088_1478_3975_12_4_045008 crossref_primary_10_1088_1478_3975_12_4_045007 crossref_primary_10_1371_journal_pcbi_1010205 crossref_primary_10_1038_s41467_019_12270_x crossref_primary_10_1523_JNEUROSCI_2866_14_2015 crossref_primary_10_1016_j_ymben_2014_03_007 crossref_primary_10_1186_1752_0509_7_18 crossref_primary_10_1091_mbc_e14_08_1333 crossref_primary_10_1088_2516_1091_ac2cdf crossref_primary_10_7554_eLife_24998 crossref_primary_10_3389_fimmu_2019_01425 crossref_primary_10_1093_bib_bbv081 crossref_primary_10_1016_j_drudis_2010_10_001 crossref_primary_10_1016_j_jmb_2019_06_008 crossref_primary_10_1093_jxb_ery435 crossref_primary_10_1186_1752_0509_6_33 crossref_primary_10_1186_1752_0509_4_92 crossref_primary_10_1186_s12918_018_0553_2 crossref_primary_10_1186_s12918_016_0264_5 crossref_primary_10_1093_genetics_iyad152 crossref_primary_10_1186_s12918_015_0151_5 crossref_primary_10_1186_1752_0509_5_165 crossref_primary_10_1016_j_ejps_2019_05_017 crossref_primary_10_26508_lsa_201800029 crossref_primary_10_3389_fimmu_2014_00172 crossref_primary_10_5301_tj_5000673 crossref_primary_10_3390_ijms22147590 crossref_primary_10_1016_j_jaci_2017_12_992 crossref_primary_10_1515_jib_2025_0007 crossref_primary_10_1158_0008_5472_CAN_09_3234 crossref_primary_10_1093_nar_gkr1004 crossref_primary_10_1016_j_csbj_2014_11_006 crossref_primary_10_1039_C4TX00058G crossref_primary_10_3389_fimmu_2023_1257321 crossref_primary_10_1038_s44320_023_00007_4 crossref_primary_10_1038_nprot_2017_144 crossref_primary_10_1177_1473871611413565 crossref_primary_10_3390_ijms221910353 crossref_primary_10_1371_journal_pone_0128985 crossref_primary_10_1016_j_bpc_2018_11_003 crossref_primary_10_3390_metabo5020232 crossref_primary_10_1371_journal_pcbi_1010408 crossref_primary_10_1186_s12918_015_0174_y crossref_primary_10_1186_1754_1611_3_15 crossref_primary_10_1371_journal_pone_0051822 crossref_primary_10_1002_pmic_201300230 crossref_primary_10_1093_bioinformatics_btp495 crossref_primary_10_2217_fmb_10_8 crossref_primary_10_3389_fphys_2019_00288 crossref_primary_10_1016_j_csbj_2024_10_045 crossref_primary_10_1016_j_drudis_2013_12_011 crossref_primary_10_1177_14738716211028136 crossref_primary_10_1186_s13742_015_0102_5 crossref_primary_10_1038_s41598_021_01618_3 crossref_primary_10_1093_nar_gkac373 crossref_primary_10_1186_s12918_016_0285_0 crossref_primary_10_1186_s13293_021_00367_2 crossref_primary_10_3389_fcell_2023_1201673 crossref_primary_10_3389_fimmu_2021_639491 crossref_primary_10_1186_s12859_020_3415_z crossref_primary_10_1016_j_csbj_2025_09_008 crossref_primary_10_1093_synbio_ysab022 crossref_primary_10_15252_msb_202211036 crossref_primary_10_1186_s12859_016_1000_2 crossref_primary_10_1038_s41597_020_0477_8 crossref_primary_10_1038_s41598_020_67564_8 crossref_primary_10_1109_TBME_2016_2555481 crossref_primary_10_1016_j_mrgentox_2011_12_016 crossref_primary_10_3389_fbioe_2014_00061 crossref_primary_10_1155_2013_703849 crossref_primary_10_1039_C4CS00351A crossref_primary_10_1093_nar_gkv450 crossref_primary_10_1371_journal_pcbi_1005396 crossref_primary_10_1038_npjsba_2016_32 crossref_primary_10_1177_1933719119831769 crossref_primary_10_1111_bph_70129 crossref_primary_10_3389_fimmu_2023_1282859 crossref_primary_10_1371_journal_pone_0265735 crossref_primary_10_1186_s12864_015_2108_x crossref_primary_10_3390_biom12091278 crossref_primary_10_3389_fphys_2018_00646 crossref_primary_10_1093_nar_gkz946 crossref_primary_10_1371_journal_pcbi_1007799 crossref_primary_10_1111_cgf_13610 crossref_primary_10_1016_j_procs_2012_01_047 crossref_primary_10_1093_nar_gkq1018 crossref_primary_10_1051_mmnp_201510314 crossref_primary_10_1016_j_steroids_2015_02_022 crossref_primary_10_1371_journal_pone_0115533 crossref_primary_10_1016_j_jbiotec_2015_12_023 crossref_primary_10_1104_pp_109_150821 crossref_primary_10_1515_disp_2017_0014 crossref_primary_10_3390_jpm11080785 crossref_primary_10_1007_s43393_021_00059_3 crossref_primary_10_1186_1752_0509_7_97 crossref_primary_10_1186_1471_2229_13_72 crossref_primary_10_1186_1752_0509_8_70 crossref_primary_10_1371_journal_pcbi_1004085 crossref_primary_10_15252_msb_20177651 crossref_primary_10_1111_bph_14037 crossref_primary_10_1016_j_bbagen_2018_07_008 crossref_primary_10_1186_1471_2229_12_245 crossref_primary_10_1093_bib_bbt058 crossref_primary_10_1186_1752_0509_8_54 crossref_primary_10_3390_ijms24087296 crossref_primary_10_3109_0954898X_2012_722743 crossref_primary_10_1186_1471_2105_10_371 crossref_primary_10_1371_journal_pone_0197238 crossref_primary_10_1093_nar_gkq1039 crossref_primary_10_1089_nsm_2020_0004 crossref_primary_10_3389_fmicb_2018_00296 crossref_primary_10_1007_s00521_021_05711_6 crossref_primary_10_1371_journal_pcbi_1010623 crossref_primary_10_1080_1547691X_2024_2345154 crossref_primary_10_1371_journal_pone_0187568 crossref_primary_10_1002_art_38297 crossref_primary_10_1016_j_csbj_2023_08_015 crossref_primary_10_1111_cgf_14575 crossref_primary_10_20965_jrm_2010_p0669 crossref_primary_10_1016_j_cels_2020_06_012 crossref_primary_10_1111_febs_13267 crossref_primary_10_1371_journal_pcbi_1006680 crossref_primary_10_1371_journal_pcbi_1003299 crossref_primary_10_1371_journal_pcbi_1006685 crossref_primary_10_1146_annurev_phyto_073009_114411 crossref_primary_10_1098_rsob_150042 crossref_primary_10_1186_s12918_015_0181_z crossref_primary_10_1093_bib_bbs070 crossref_primary_10_1109_TBDATA_2021_3050680 crossref_primary_10_3390_pharmaceutics17070935 crossref_primary_10_1186_1752_0509_7_135 crossref_primary_10_1177_0271678X17693024 crossref_primary_10_3390_molecules22010105 crossref_primary_10_1371_journal_pcbi_1004246 crossref_primary_10_1002_psp4_12972 crossref_primary_10_1016_j_biosystems_2010_12_001 crossref_primary_10_1093_nar_gkz861 crossref_primary_10_1093_bib_bbs064 crossref_primary_10_1007_s12038_023_00370_2 crossref_primary_10_1038_s41540_019_0114_3 crossref_primary_10_1007_s00438_014_0843_3 crossref_primary_10_1038_s41598_018_26006_2 crossref_primary_10_1039_C5IB00029G crossref_primary_10_1186_s12859_019_2779_4 crossref_primary_10_1186_1752_0509_7_100 crossref_primary_10_1093_nar_gks1118 crossref_primary_10_1038_s41588_019_0500_1 crossref_primary_10_1016_j_csbj_2022_10_003 crossref_primary_10_1016_j_ymben_2012_03_001 crossref_primary_10_1186_s12859_018_2314_z crossref_primary_10_1038_nmeth_f_301 crossref_primary_10_1186_1471_2105_14_17 crossref_primary_10_1016_j_ejps_2011_10_026 crossref_primary_10_1109_TVCG_2017_2747545 crossref_primary_10_1002_bies_201100172 crossref_primary_10_1016_j_coisb_2021_06_001 crossref_primary_10_1007_s00354_019_00066_y crossref_primary_10_1186_1752_0509_7_116 crossref_primary_10_1186_1752_0509_7_115 crossref_primary_10_3390_cells10082007 crossref_primary_10_1007_s10539_012_9311_9 crossref_primary_10_1016_j_jmb_2019_01_044 crossref_primary_10_1002_pmic_201100066 crossref_primary_10_1016_j_algal_2019_101510 crossref_primary_10_1186_s12918_015_0213_8 crossref_primary_10_1016_j_isci_2023_107917 crossref_primary_10_1038_npjsba_2016_20 crossref_primary_10_1016_j_bioelechem_2020_107636 crossref_primary_10_1038_s41598_023_40008_9 crossref_primary_10_1038_s41540_018_0059_y crossref_primary_10_1002_wsbm_1245 crossref_primary_10_1186_s12859_016_1443_5 crossref_primary_10_1093_bib_bbae561 crossref_primary_10_1016_j_jvlc_2015_10_013 crossref_primary_10_1186_ar3438 crossref_primary_10_3390_pr6080115 crossref_primary_10_1016_j_shpsc_2013_03_017 crossref_primary_10_1186_1752_0509_6_6 crossref_primary_10_3390_computation11060107 crossref_primary_10_1371_journal_pone_0066811 crossref_primary_10_1016_j_immuno_2025_100060 crossref_primary_10_1093_nar_gkr1208 crossref_primary_10_1089_big_2015_0057 crossref_primary_10_1089_omi_2013_0007 crossref_primary_10_1093_bib_bbab049 crossref_primary_10_12688_f1000research_9379_1 crossref_primary_10_1371_journal_pbio_1000472 crossref_primary_10_1371_journal_pbio_1002530 crossref_primary_10_1182_blood_2011_11_390666 crossref_primary_10_3390_cancers4041180 crossref_primary_10_1038_nprot_2012_002 crossref_primary_10_1109_TBME_2016_2591960 crossref_primary_10_3390_metabo5040659 crossref_primary_10_1038_nrg3096 crossref_primary_10_1371_journal_pone_0160834 crossref_primary_10_1093_nar_gkq973 crossref_primary_10_1088_1478_3975_9_4_045003 crossref_primary_10_1186_s12918_015_0212_9 crossref_primary_10_1038_s41467_017_00268_2 crossref_primary_10_1016_j_copbio_2010_09_014 crossref_primary_10_1111_febs_14022 crossref_primary_10_3389_fpls_2016_01936 crossref_primary_10_3389_fbioe_2015_00019 crossref_primary_10_1007_s11538_018_0498_z crossref_primary_10_1186_s12859_023_05329_6 crossref_primary_10_1371_journal_pone_0146759 crossref_primary_10_1073_pnas_1809609115 crossref_primary_10_1093_nar_gkv399 crossref_primary_10_1186_s12859_019_2863_9 crossref_primary_10_1016_j_conb_2023_102808 crossref_primary_10_1186_1471_2105_13_85 crossref_primary_10_1038_msb_2010_108 crossref_primary_10_1111_j_1742_4658_2012_08582_x crossref_primary_10_1007_s11432_020_3219_6 crossref_primary_10_1016_j_imbio_2013_07_002 crossref_primary_10_1038_npjsba_2015_18 crossref_primary_10_1007_s00204_010_0577_x crossref_primary_10_1177_1473871617714520 crossref_primary_10_1016_j_biosystems_2014_05_004 crossref_primary_10_7554_eLife_63661 crossref_primary_10_7554_eLife_41412 crossref_primary_10_1038_s41746_024_01396_y crossref_primary_10_1042_BST20160347 crossref_primary_10_1371_journal_pone_0015165 |
| Cites_doi | 10.1006/dbio.2002.0619 10.1111/j.1551-6708.1987.tb00863.x 10.1093/bioinformatics/btg015 10.1016/S1478-5382(03)02370-9 10.1016/S1535-6108(02)00133-2 10.1093/bioinformatics/18.7.996 10.1515/jib-2006-36 10.1057/palgrave.ivs.9500102 10.1186/1752-0509-2-36 10.1038/sj.onc.1201608 10.1016/j.bbagrm.2008.07.014 10.1091/mbc.10.8.2703 10.1109/JPROC.2008.925458 10.1016/S0962-8924(00)01817-1 10.1046/j.1432-1327.2000.01197.x 10.1091/mbc.e05-09-0824 10.1089/153623103322637670 10.1093/bioinformatics/btg416 10.1007/3-540-44590-0_32 10.1016/S1478-5382(03)02380-1 10.1038/nbt1111 10.1186/gb-2001-2-4-research0012 |
| ContentType | Journal Article |
| Copyright | Springer Nature America, Inc. 2009 COPYRIGHT 2009 Nature Publishing Group Copyright Nature Publishing Group Aug 2009 |
| Copyright_xml | – notice: Springer Nature America, Inc. 2009 – notice: COPYRIGHT 2009 Nature Publishing Group – notice: Copyright Nature Publishing Group Aug 2009 |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM N95 IOV ISR 3V. 7QO 7QP 7QR 7T7 7TK 7TM 7X7 7XB 88A 88E 88I 8AO 8FD 8FE 8FG 8FH 8FI 8FJ 8FK 8G5 ABJCF ABUWG AEUYN AFKRA AZQEC BBNVY BENPR BGLVJ BHPHI C1K CCPQU DWQXO FR3 FYUFA GHDGH GNUQQ GUQSH HCIFZ K9. L6V LK8 M0S M1P M2O M2P M7P M7S MBDVC P64 PHGZM PHGZT PJZUB PKEHL PPXIY PQEST PQGLB PQQKQ PQUKI PTHSS Q9U RC3 7X8 |
| DOI | 10.1038/nbt.1558 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Gale Business: Insights Gale In Context: Opposing Viewpoints Gale In Context: Science ProQuest Central (Corporate) Biotechnology Research Abstracts Calcium & Calcified Tissue Abstracts Chemoreception Abstracts Industrial and Applied Microbiology Abstracts (Microbiology A) Neurosciences Abstracts Nucleic Acids Abstracts Health & Medical Collection ProQuest Central (purchase pre-March 2016) Biology Database (Alumni Edition) Medical Database (Alumni Edition) Science Database (Alumni Edition) ProQuest Pharma Collection Technology Research Database ProQuest SciTech Collection ProQuest Technology Collection ProQuest Natural Science Collection ProQuest Hospital Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) Research Library (Alumni) ProQuest Materials Science & Engineering ProQuest Central (Alumni) ProQuest One Sustainability ProQuest Central UK/Ireland ProQuest Central Essentials Biological Science Collection ProQuest Central Technology Collection Natural Science Collection Environmental Sciences and Pollution Management ProQuest One ProQuest Central Engineering Research Database Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student ProQuest Research Library SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) ProQuest Engineering Collection Biological Sciences ProQuest Health & Medical Collection Medical Database Research Library Science Database Biological Science Database Engineering Database Research Library (Corporate) Biotechnology and BioEngineering Abstracts ProQuest Central Premium ProQuest One Academic (New) ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Applied & Life Sciences ProQuest One Academic (retired) ProQuest One Academic UKI Edition Engineering Collection ProQuest Central Basic Genetics Abstracts MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Research Library Prep ProQuest Central Student ProQuest Central Essentials Nucleic Acids Abstracts SciTech Premium Collection Environmental Sciences and Pollution Management ProQuest One Applied & Life Sciences ProQuest One Sustainability Health Research Premium Collection Natural Science Collection Health & Medical Research Collection Biological Science Collection Chemoreception Abstracts Industrial and Applied Microbiology Abstracts (Microbiology A) ProQuest Central (New) ProQuest Medical Library (Alumni) Engineering Collection Engineering Database ProQuest Science Journals (Alumni Edition) ProQuest Biological Science Collection ProQuest One Academic Eastern Edition ProQuest Hospital Collection ProQuest Technology Collection Health Research Premium Collection (Alumni) Biological Science Database Neurosciences Abstracts ProQuest Hospital Collection (Alumni) Biotechnology and BioEngineering Abstracts ProQuest Health & Medical Complete ProQuest One Academic UKI Edition Engineering Research Database ProQuest One Academic Calcium & Calcified Tissue Abstracts ProQuest One Academic (New) Technology Collection Technology Research Database ProQuest One Academic Middle East (New) ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing Research Library (Alumni Edition) ProQuest Natural Science Collection ProQuest Pharma Collection ProQuest Biology Journals (Alumni Edition) ProQuest Central ProQuest Health & Medical Research Collection Genetics Abstracts ProQuest Engineering Collection Biotechnology Research Abstracts Health and Medicine Complete (Alumni Edition) ProQuest Central Korea ProQuest Research Library ProQuest Central Basic ProQuest Science Journals ProQuest SciTech Collection ProQuest Medical Library Materials Science & Engineering Collection ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | Research Library Prep Engineering Research Database MEDLINE MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: BENPR name: ProQuest Central (subscription) url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Engineering Agriculture Biology Chemistry |
| EISSN | 1546-1696 |
| EndPage | 741 |
| ExternalDocumentID | 1825817581 A206534642 19668183 10_1038_nbt_1558 |
| Genre | Historical Article Research Support, N.I.H., Intramural Research Support, Non-U.S. Gov't Journal Article Research Support, N.I.H., Extramural |
| GrantInformation_xml | – fundername: Intramural NIH HHS – fundername: NIGMS NIH HHS grantid: 1R01GM081070-01 – fundername: Biotechnology and Biological Sciences Research Council grantid: BB/F010516/1 – fundername: Chief Scientist Office grantid: ETM/202 – fundername: Biotechnology and Biological Sciences Research Council grantid: BB/D019621/1 – fundername: Biotechnology and Biological Sciences Research Council grantid: BBS/E/D/05191131 – fundername: Biotechnology and Biological Sciences Research Council grantid: BB/E016065/1 |
| GroupedDBID | --- -~X .55 .GJ 0R~ 123 29M 2FS 2XV 36B 39C 4.4 4R4 53G 5M7 5RE 5S5 70F 7X7 88E 88I 8AO 8CJ 8FE 8FG 8FH 8FI 8FJ 8G5 8R4 8R5 A8Z AAHBH AAIKC AAMNW AARCD ABDBF ABDPE ABEFU ABFSG ABJCF ABJNI ABLJU ABOCM ABUWG ACBTR ACBWK ACGFO ACGFS ACGOD ACIWK ACMJI ACPRK ACSTC ACUHS ADBBV ADFRT AENEX AEUYN AEZWR AFANA AFBBN AFFHD AFFNX AFHIU AFKRA AFRAH AFSHS AGAYW AGSTI AHBCP AHMBA AHOSX AHSBF AHWEU AIBTJ AIXLP ALFFA ALMA_UNASSIGNED_HOLDINGS ALPWD AMTXH ARMCB ASPBG ATHPR AVWKF AXYYD AZFZN AZQEC BAAKF BBNVY BENPR BGLVJ BHPHI BKKNO BKOMP BPHCQ BVXVI C0K CCPQU D1J DB5 DU5 DWQXO EAD EAP EAS EBC EBS EE. EJD EMB EMK EMOBN ESTFP ESX EXGXG F5P FA8 FEDTE FQGFK FSGXE FYUFA GNUQQ GUQSH GX1 HCIFZ HMCUK HVGLF HZ~ IAG IAO IEA IEP IH2 IHR INH INR IOV ISR ITC KOO L6V LGEZI LK8 LOTEE M1P M2O M2P M7P M7S ML0 MVM N95 NADUK NEJ NFIDA NNMJJ NXXTH O9- ODYON P2P PHGZM PHGZT PJZUB PPXIY PQGLB PQQKQ PROAC PSQYO PTHSS Q2X QF4 QM4 QN7 QO4 RNS RNT RNTTT RVV RXW SHXYY SIXXV SJN SNYQT SOJ SV3 TAE TAOOD TBHMF TDRGL TN5 TSG TUS U5U UKHRP X7M XOL Y6R YZZ ZGI ZXP ~KM AAYXX CITATION 5BI AAYOK AAYZH ABAWZ ACMFV ALIPV CGR CUY CVF ECM EIF NPM PMFND 3V. 7QO 7QP 7QR 7T7 7TK 7TM 7XB 88A 8FD 8FK C1K FR3 K9. MBDVC P64 PKEHL PQEST PQUKI Q9U RC3 7X8 PUEGO |
| ID | FETCH-LOGICAL-c580t-d0e7fb3218cd95edf6baed46695fdc4c6a2e14eec7916d2610e0601a8060b3013 |
| IEDL.DBID | M7P |
| ISICitedReferencesCount | 626 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000268774500023&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1087-0156 1546-1696 |
| IngestDate | Thu Oct 02 14:55:31 EDT 2025 Tue Oct 07 09:20:59 EDT 2025 Tue Oct 07 05:10:04 EDT 2025 Sat Nov 29 13:51:23 EST 2025 Mon Nov 24 15:42:51 EST 2025 Mon Nov 24 14:57:03 EST 2025 Mon Nov 24 14:57:00 EST 2025 Sat Nov 29 09:18:07 EST 2025 Fri May 30 10:59:24 EDT 2025 Sat Nov 29 06:43:19 EST 2025 Tue Nov 18 22:40:02 EST 2025 Mon Nov 10 01:23:35 EST 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 8 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c580t-d0e7fb3218cd95edf6baed46695fdc4c6a2e14eec7916d2610e0601a8060b3013 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| OpenAccessLink | https://www.nature.com/articles/nbt.1558.pdf |
| PMID | 19668183 |
| PQID | 222307798 |
| PQPubID | 47191 |
| PageCount | 7 |
| ParticipantIDs | proquest_miscellaneous_733967403 proquest_miscellaneous_21220523 proquest_journals_222307798 gale_infotracmisc_A206534642 gale_infotracacademiconefile_A206534642 gale_incontextgauss_ISR_A206534642 gale_incontextgauss_IOV_A206534642 gale_businessinsightsgauss_A206534642 pubmed_primary_19668183 crossref_citationtrail_10_1038_nbt_1558 crossref_primary_10_1038_nbt_1558 springer_journals_10_1038_nbt_1558 |
| PublicationCentury | 2000 |
| PublicationDate | 2009-08-01 |
| PublicationDateYYYYMMDD | 2009-08-01 |
| PublicationDate_xml | – month: 08 year: 2009 text: 2009-08-01 day: 01 |
| PublicationDecade | 2000 |
| PublicationPlace | New York |
| PublicationPlace_xml | – name: New York – name: United States |
| PublicationSubtitle | The Science and Business of Biotechnology |
| PublicationTitle | Nature biotechnology |
| PublicationTitleAbbrev | Nat Biotechnol |
| PublicationTitleAlternate | Nat Biotechnol |
| PublicationYear | 2009 |
| Publisher | Nature Publishing Group US Nature Publishing Group |
| Publisher_xml | – name: Nature Publishing Group US – name: Nature Publishing Group |
| References | Britton, Jones, Kutar, Loomes, Robinson (CR25) 2000 Raza (CR23) 2008; 2 Hucka (CR24) 2003; 19 Michal (CR5) 1984 Demir (CR10) 2002; 18 Sel'kov, Goryanin, Kaimatchnikov, Shevelev, Yunus (CR6) 1989; 129 CR16 Larkin, Simon (CR1) 1987; 11 CR33 CR32 Demir (CR20) 2004; 20 Moodie, Sorokin, Goryanin, Ghazal (CR22) 2006; 3 CR30 Sauro (CR11) 2003; 7 Riechelmann (CR31) 2004; 3 Goto (CR8) 1997; PSB97 Funahashi, Morohashi, Kitano, Tanimura (CR12) 2003; 1 Funahashi (CR28) 2008; 96 Kohn (CR18) 1999; 10 Kohn, Aladjem, Weinstein, Pommier (CR19) 2006; 17 Saraiya, North, Duca (CR27) 2005; 4 Lazebnik (CR2) 2002; 2 Karp, Paley (CR7) 1994; 2 Longabaugh, Davidson, Bolouri (CR17) 2009; 1789 Kitano, Funahashi, Matsuoka, Oda (CR21) 2005; 23 Pirson (CR15) 2000; 10 Kohn (CR13) 1998; 16 Gortner (CR3) 1949 Dagley, Nicholson (CR4) 1970 Narayanan, Hübscher (CR26) 1998 Kholodenko (CR34) 2000; 267 Kitano (CR14) 2003; 1 Brown (CR9) 2002; 246 Le Novère, Courtot, Laibe (CR29) 2007 M Hucka (BFnbt1558_CR24) 2003; 19 H Riechelmann (BFnbt1558_CR31) 2004; 3 E Demir (BFnbt1558_CR20) 2004; 20 RA Gortner (BFnbt1558_CR3) 1949 WJR Longabaugh (BFnbt1558_CR17) 2009; 1789 EE Sel'kov (BFnbt1558_CR6) 1989; 129 N Le Novère (BFnbt1558_CR29) 2007 G Michal (BFnbt1558_CR5) 1984 Y Lazebnik (BFnbt1558_CR2) 2002; 2 NH Narayanan (BFnbt1558_CR26) 1998 KW Kohn (BFnbt1558_CR18) 1999; 10 P Saraiya (BFnbt1558_CR27) 2005; 4 B Kholodenko (BFnbt1558_CR34) 2000; 267 CT Brown (BFnbt1558_CR9) 2002; 246 KW Kohn (BFnbt1558_CR13) 1998; 16 H Kitano (BFnbt1558_CR21) 2005; 23 PD Karp (BFnbt1558_CR7) 1994; 2 A Funahashi (BFnbt1558_CR12) 2003; 1 C Britton (BFnbt1558_CR25) 2000 BFnbt1558_CR16 S Goto (BFnbt1558_CR8) 1997; PSB97 I Pirson (BFnbt1558_CR15) 2000; 10 A Funahashi (BFnbt1558_CR28) 2008; 96 SL Moodie (BFnbt1558_CR22) 2006; 3 S Dagley (BFnbt1558_CR4) 1970 KW Kohn (BFnbt1558_CR19) 2006; 17 E Demir (BFnbt1558_CR10) 2002; 18 BFnbt1558_CR32 H Kitano (BFnbt1558_CR14) 2003; 1 BFnbt1558_CR33 JH Larkin (BFnbt1558_CR1) 1987; 11 S Raza (BFnbt1558_CR23) 2008; 2 BFnbt1558_CR30 HM Sauro (BFnbt1558_CR11) 2003; 7 Nat Biotechnol. 2009 Sep;27(9):864 |
| References_xml | – volume: 246 start-page: 86 year: 2002 end-page: 102 ident: CR9 article-title: New computational approaches for analysis of cis-regulatory networks publication-title: Dev. Biol. doi: 10.1006/dbio.2002.0619 – ident: CR16 – ident: CR30 – volume: 11 start-page: 65 year: 1987 end-page: 100 ident: CR1 article-title: Why a diagram is (sometimes) worth ten thousands words publication-title: Cogn. Sci. doi: 10.1111/j.1551-6708.1987.tb00863.x – volume: 19 start-page: 524 year: 2003 end-page: 531 ident: CR24 article-title: The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models publication-title: Bioinformatics doi: 10.1093/bioinformatics/btg015 – ident: CR33 – volume: 1 start-page: 159 year: 2003 end-page: 162 ident: CR12 article-title: CellDesigner: a process diagram editor for gene-regulatory and biochemical networks publication-title: BIOSILICO doi: 10.1016/S1478-5382(03)02370-9 – volume: 2 start-page: 179 year: 2002 end-page: 182 ident: CR2 article-title: Can a biologist fix a radio?—Or,what I learned while studying apoptosis publication-title: Cancer Cell doi: 10.1016/S1535-6108(02)00133-2 – volume: 18 start-page: 996 year: 2002 end-page: 1003 ident: CR10 article-title: PATIKA: an integrated visual environment for collaborative construction and analysis of cellular pathways publication-title: Bioinformatics doi: 10.1093/bioinformatics/18.7.996 – year: 1970 ident: CR4 publication-title: An Introduction to Metabolic Pathways – volume: PSB97 start-page: 175 year: 1997 end-page: 186 ident: CR8 article-title: Organizing and computing metabolic pathway data in terms of binary relations publication-title: Pac. Symp. Biocomput. – volume: 3 start-page: 36 year: 2006 end-page: 46 ident: CR22 article-title: A graphical notation to describe the logical interactions of biological pathways publication-title: J. Integr. Bioinform. doi: 10.1515/jib-2006-36 – volume: 4 start-page: 191 year: 2005 end-page: 205 ident: CR27 article-title: Visualizing biological pathways: requirements analysis, systems evaluation and research agenda publication-title: Inform. Visual doi: 10.1057/palgrave.ivs.9500102 – volume: 2 start-page: 36 year: 2008 ident: CR23 article-title: A logic-based diagram of signalling pathways central to macrophage activation publication-title: BMC Syst. Biol. doi: 10.1186/1752-0509-2-36 – volume: 3 start-page: Doc02 year: 2004 ident: CR31 article-title: Cellular and molecular mechanisms in environmental and occupational inhalation toxicology publication-title: GMS Cur. Topics. Otorhinolaryngol.—Head Neck Surg. – volume: 16 start-page: 1065 year: 1998 end-page: 1075 ident: CR13 article-title: Functional capabilities of molecular network components controlling the mammalian G1/S cell cycle phase transition publication-title: Oncogene doi: 10.1038/sj.onc.1201608 – volume: 1789 start-page: 363 year: 2009 end-page: 374 ident: CR17 article-title: Visualization, documentation, analysis, and communication of large-scale gene regulatory networks publication-title: Biochim. Biophys. Acta doi: 10.1016/j.bbagrm.2008.07.014 – year: 1984 ident: CR5 publication-title: Biochemical Pathways (wall chart) – volume: 10 start-page: 2703 year: 1999 end-page: 2734 ident: CR18 article-title: Molecular interaction map of the mammalian cell cycle control and DNA repair systems publication-title: Mol. Biol. Cell doi: 10.1091/mbc.10.8.2703 – volume: 96 start-page: 1254 year: 2008 end-page: 1265 ident: CR28 article-title: CellDesigner 3.5: a versatile modeling tool for biochemical networks publication-title: Proc. IEEE doi: 10.1109/JPROC.2008.925458 – volume: 129 start-page: 155 year: 1989 end-page: 164 ident: CR6 article-title: Factographic data bank on enzymes and metabolic pathways publication-title: Studia Biophysica – volume: 10 start-page: 404 year: 2000 end-page: 408 ident: CR15 article-title: The visual display of regulatory information and networks publication-title: Trends Cell Biol. doi: 10.1016/S0962-8924(00)01817-1 – year: 2007 ident: CR29 article-title: Adding semantics in kinetics models of biochemical pathways publication-title: Proc. 2 Intl. Symp. Exp. Stand. Cond. Enzyme Characterizations – volume: 267 start-page: 1583 year: 2000 end-page: 1588 ident: CR34 article-title: Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades publication-title: Eur. J. Biochem. doi: 10.1046/j.1432-1327.2000.01197.x – start-page: 85 year: 1998 end-page: 127 ident: CR26 article-title: Visual language theory: towards a human-computer interaction perspective publication-title: Visual Language Theory – volume: 17 start-page: 1 year: 2006 end-page: 13 ident: CR19 article-title: Molecular interaction maps of bioregulatory networks: a general rubric for systems biology publication-title: Mol. Biol. Cell doi: 10.1091/mbc.e05-09-0824 – volume: 2 start-page: 203 year: 1994 end-page: 211 ident: CR7 article-title: Representations of metabolic knowledge: pathways publication-title: Proc. Int. Conf. Intell. Syst. Mol. Biol. – ident: CR32 – volume: 7 start-page: 355 year: 2003 end-page: 372 ident: CR11 article-title: Next generation simulation tools: the Systems Biology Workbench and BioSPICE integration publication-title: OMICS doi: 10.1089/153623103322637670 – year: 1949 ident: CR3 publication-title: Outlines of Biochemistry – volume: 20 start-page: 349 year: 2004 end-page: 356 ident: CR20 article-title: An ontology for collaborative construction and analysis of cellular pathways publication-title: Bioinformatics doi: 10.1093/bioinformatics/btg416 – start-page: 376 year: 2000 end-page: 391 ident: CR25 article-title: Evaluating the intelligibility of diagrammatic languages used in the specification of software publication-title: Theory and Application of Diagrams: Diagrams 2000 doi: 10.1007/3-540-44590-0_32 – volume: 1 start-page: 169 year: 2003 end-page: 176 ident: CR14 article-title: A graphical notation for biochemical networks publication-title: BIOSILICO doi: 10.1016/S1478-5382(03)02380-1 – volume: 23 start-page: 961 year: 2005 end-page: 966 ident: CR21 article-title: Using process diagrams for the graphical representation of biological networks publication-title: Nat. Biotechnol. doi: 10.1038/nbt1111 – ident: BFnbt1558_CR16 doi: 10.1186/gb-2001-2-4-research0012 – volume: 10 start-page: 404 year: 2000 ident: BFnbt1558_CR15 publication-title: Trends Cell Biol. doi: 10.1016/S0962-8924(00)01817-1 – volume: 20 start-page: 349 year: 2004 ident: BFnbt1558_CR20 publication-title: Bioinformatics doi: 10.1093/bioinformatics/btg416 – ident: BFnbt1558_CR30 – volume: 1789 start-page: 363 year: 2009 ident: BFnbt1558_CR17 publication-title: Biochim. Biophys. Acta doi: 10.1016/j.bbagrm.2008.07.014 – volume-title: Proc. 2nd Intl. Symp. Exp. Stand. Cond. Enzyme Characterizations year: 2007 ident: BFnbt1558_CR29 – volume: 16 start-page: 1065 year: 1998 ident: BFnbt1558_CR13 publication-title: Oncogene doi: 10.1038/sj.onc.1201608 – volume-title: An Introduction to Metabolic Pathways year: 1970 ident: BFnbt1558_CR4 – volume: 1 start-page: 169 year: 2003 ident: BFnbt1558_CR14 publication-title: BIOSILICO doi: 10.1016/S1478-5382(03)02380-1 – start-page: 85 volume-title: Visual Language Theory year: 1998 ident: BFnbt1558_CR26 – volume: 96 start-page: 1254 year: 2008 ident: BFnbt1558_CR28 publication-title: Proc. IEEE doi: 10.1109/JPROC.2008.925458 – volume-title: Biochemical Pathways (wall chart) year: 1984 ident: BFnbt1558_CR5 – volume: 10 start-page: 2703 year: 1999 ident: BFnbt1558_CR18 publication-title: Mol. Biol. Cell doi: 10.1091/mbc.10.8.2703 – ident: BFnbt1558_CR32 – volume: PSB97 start-page: 175 year: 1997 ident: BFnbt1558_CR8 publication-title: Pac. Symp. Biocomput. – volume: 19 start-page: 524 year: 2003 ident: BFnbt1558_CR24 publication-title: Bioinformatics doi: 10.1093/bioinformatics/btg015 – volume: 3 start-page: Doc02 year: 2004 ident: BFnbt1558_CR31 publication-title: GMS Cur. Topics. Otorhinolaryngol.—Head Neck Surg. – volume: 129 start-page: 155 year: 1989 ident: BFnbt1558_CR6 publication-title: Studia Biophysica – volume: 11 start-page: 65 year: 1987 ident: BFnbt1558_CR1 publication-title: Cogn. Sci. doi: 10.1111/j.1551-6708.1987.tb00863.x – volume: 7 start-page: 355 year: 2003 ident: BFnbt1558_CR11 publication-title: OMICS doi: 10.1089/153623103322637670 – volume: 2 start-page: 36 year: 2008 ident: BFnbt1558_CR23 publication-title: BMC Syst. Biol. doi: 10.1186/1752-0509-2-36 – volume: 18 start-page: 996 year: 2002 ident: BFnbt1558_CR10 publication-title: Bioinformatics doi: 10.1093/bioinformatics/18.7.996 – volume-title: Outlines of Biochemistry year: 1949 ident: BFnbt1558_CR3 – start-page: 376 volume-title: Theory and Application of Diagrams: Diagrams 2000 year: 2000 ident: BFnbt1558_CR25 doi: 10.1007/3-540-44590-0_32 – volume: 2 start-page: 203 year: 1994 ident: BFnbt1558_CR7 publication-title: Proc. Int. Conf. Intell. Syst. Mol. Biol. – ident: BFnbt1558_CR33 – volume: 3 start-page: 36 year: 2006 ident: BFnbt1558_CR22 publication-title: J. Integr. Bioinform. doi: 10.1515/jib-2006-36 – volume: 4 start-page: 191 year: 2005 ident: BFnbt1558_CR27 publication-title: Inform. Visual doi: 10.1057/palgrave.ivs.9500102 – volume: 1 start-page: 159 year: 2003 ident: BFnbt1558_CR12 publication-title: BIOSILICO doi: 10.1016/S1478-5382(03)02370-9 – volume: 17 start-page: 1 year: 2006 ident: BFnbt1558_CR19 publication-title: Mol. Biol. Cell doi: 10.1091/mbc.e05-09-0824 – volume: 23 start-page: 961 year: 2005 ident: BFnbt1558_CR21 publication-title: Nat. Biotechnol. doi: 10.1038/nbt1111 – volume: 246 start-page: 86 year: 2002 ident: BFnbt1558_CR9 publication-title: Dev. Biol. doi: 10.1006/dbio.2002.0619 – volume: 2 start-page: 179 year: 2002 ident: BFnbt1558_CR2 publication-title: Cancer Cell doi: 10.1016/S1535-6108(02)00133-2 – volume: 267 start-page: 1583 year: 2000 ident: BFnbt1558_CR34 publication-title: Eur. J. Biochem. doi: 10.1046/j.1432-1327.2000.01197.x – reference: - Nat Biotechnol. 2009 Sep;27(9):864 |
| SSID | ssj0006466 |
| Score | 2.5317106 |
| SecondaryResourceType | review_article |
| Snippet | A group of scientists in the systems biology community propose visual conventions for drawing biological diagrams.
Circuit diagrams and Unified Modeling... Circuit diagrams and Unified Modeling Language diagrams are just two examples of standard visual languages that help accelerate work by promoting regularity,... |
| SourceID | proquest gale pubmed crossref springer |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 735 |
| SubjectTerms | Agriculture Biochemistry Bioinformatics Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biomedical research Biomedicine Biotechnology Chemistry Computer Graphics - history History, 20th Century Information management Internet Life Sciences Notation perspective Scientists Software Symbols Systems biology Systems Biology - history Visual programming (Computer science) Visual programming languages (Computer science) |
| Title | The Systems Biology Graphical Notation |
| URI | https://link.springer.com/article/10.1038/nbt.1558 https://www.ncbi.nlm.nih.gov/pubmed/19668183 https://www.proquest.com/docview/222307798 https://www.proquest.com/docview/21220523 https://www.proquest.com/docview/733967403 |
| Volume | 27 |
| WOSCitedRecordID | wos000268774500023&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVPQU databaseName: Biological Science Database customDbUrl: eissn: 1546-1696 dateEnd: 20181231 omitProxy: false ssIdentifier: ssj0006466 issn: 1087-0156 databaseCode: M7P dateStart: 19970101 isFulltext: true titleUrlDefault: http://search.proquest.com/biologicalscijournals providerName: ProQuest – providerCode: PRVPQU databaseName: Engineering Database (ProQuest) customDbUrl: eissn: 1546-1696 dateEnd: 20181231 omitProxy: false ssIdentifier: ssj0006466 issn: 1087-0156 databaseCode: M7S dateStart: 19970101 isFulltext: true titleUrlDefault: http://search.proquest.com providerName: ProQuest – providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 1546-1696 dateEnd: 20181231 omitProxy: false ssIdentifier: ssj0006466 issn: 1087-0156 databaseCode: 7X7 dateStart: 19970101 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central (subscription) customDbUrl: eissn: 1546-1696 dateEnd: 20181231 omitProxy: false ssIdentifier: ssj0006466 issn: 1087-0156 databaseCode: BENPR dateStart: 19970101 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Research Library customDbUrl: eissn: 1546-1696 dateEnd: 20181231 omitProxy: false ssIdentifier: ssj0006466 issn: 1087-0156 databaseCode: M2O dateStart: 19970101 isFulltext: true titleUrlDefault: https://search.proquest.com/pqrl providerName: ProQuest – providerCode: PRVPQU databaseName: Science Database (subscription) customDbUrl: eissn: 1546-1696 dateEnd: 20181231 omitProxy: false ssIdentifier: ssj0006466 issn: 1087-0156 databaseCode: M2P dateStart: 19970101 isFulltext: true titleUrlDefault: https://search.proquest.com/sciencejournals providerName: ProQuest |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3db9MwED-xDRA88FG-wkYJE7CnsHw4tvOEBtoAiXXVNlDfosR2EBJKxtIi8d9z5zjdUgFC4uWk1r-qju98F-cuvwN4LotIYxTmAYYeHrCC4Z6jIseqUiKLtOKssJr-KCYTOZtlU1eb07qyyt4nWketG0XPyHcpjoVCZPL12feAmkZRctV10FiDDSJJSGzl3nTpiHmXqoxCSdWVKe-5ZxO5W5fzVxhJ5SAarfrkS0FpJUtqg8_B7f-c9h245e46_b3OTO7CFVOP4FrXh_LnCG5eYiUcwfVDl2-_By_RinxHau47uP-OOK5Jt_6k6RL59-HTwf7p2_eB66wQqFSG80CHRlRlguFd6Sw1uuJlYTQuV5ZWWjHFi9hEzBjSF9d4yAoN8bYUEmWJLiF5AOt1U5tH4OMJMilVGquqSFmUiTJlugwToWOG32fcg51-hXPlaMep-8W33Ka_E5mjLnLShQfPlsizjmrjN5gXpKTcdehE0dIzjPZLsWjbfC8mpl2GRyoPti2OGC5qKqHpAB-OPv8D6OR4ANpxoKrBeavCvbaAV0_MWQPk1gCJ-1QNhjd7C8mdn2jzpXl48HQ5Sj-k0rfaNAuERPQudJx44P8BIZIk44KFCHnYGezF-uFpFm_JcGS7t-CLP19d3Md_neEm3OgyaVT8uAXr8_OFeQJX1Y_51_Z8DGtiJqyUY9h4sz-ZHuOnw_jIyunY7kwrT34Byag5BA |
| linkProvider | ProQuest |
| linkToHtml | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Lb9QwEB6V8j7wWF6hhYaK0lNoHo7jHBCqgNJVt0tVCuotJLaDkFBSml1QfxT_kZnY2TYrQFx64JJD_GXX8bw8mfEMwFORBwqtMPfQ9HCP5QxljpIcy1ImaaAkZ3lL6VEyHovDw3RvAX52Z2EorbLTia2iVrWkb-QbZMf8JEnFy6NvHjWNouBq10HDcMWOPvmBHlvzYvgaybsWhltvDl5te7apgCdj4U885eukLCK0bFKlsVYlL3KtGOdpXCrJJM9DHTCtaapcoX_haypZkgu8FigNEf7uBbiIu4hQtJmCezPFz01oNPAFZXPGvKt1G4mNqpg8R8stetZv3gacMYJzUdnW2G3d_M-W6RbcsLtqd9OIwW1Y0NUALps-mycDuH6m6uIAruzafII78AylxLVF210Ld99SDW_iXXdcm0SFu_DhXGZ_DxarutIPwEUPOSpkHMoyj1mQJkXMVOFHiQoZ3k-5A-sdRTNpy6pTd4-vWRvej0SGtM-I9g48mSGPTCmR32DWiCky24EULw19o2k-59OmyTZDqiTM0GV0YLXFUQWPilKEDGD47uM_gN7v90DrFlTWOG-Z22MZ-PZUGayHXO4hUQ_J3vBSx5GZ1YNNNmNHB1Zmo_QgpfZVup4iJKCz3mHkgPsHRBJFKU-Yj5D7RkBO1w-9ddxy4shqJzGnfz6_uA__OsMVuLp9sDvKRsPxzhJcM1FDSvRchsXJ8VQ_gkvy--RLc_y4lXoXPp23_PwCwG6QUQ |
| linkToPdf | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Lb9NAEB6VFqpy4JFCMS3UVJSeTPxY79qHClWUQNQSogJVb8beXSMkZJc6AfWn8e-YsddpHQHi0gMXH7JfkvXuPDye2W8Ankapp9ALcwddD3dYylDnqMgxz6WIPSU5S-udPhSjUXRyEo8X4Gd7FobKKlubWBtqVUp6R94nP-YKEUf93FRFjPcHL06_OdRAihKtbTeNRkIO9PkPjN6q3eE-bvW27w9efXj5xjENBhwZRu7EUa4WeRagl5MqDrXKeZZqxTiPw1xJJnnqa49pTdPmCmMNVxN9SRrhNUPNCPB3r8GSIM7yumpwPHMCvEmTem5ElZ0hb3lvg6hfZJPn6MWjjiec9weXHOJchrZ2fIPb__GS3YFb5mnb3mvU4y4s6KIHN5r-m-c9uHmJjbEHy29NncEqPEPtsQ2Zu23g9mvi9iaZtkdlU8BwDz5eyezvw2JRFvoB2Bg5B5kMfZmnIfNikYVMZW4glM_w85hbsNPubiIN3Tp1_fia1Gn_IEpQDhKSAwuezJCnDcXIbzDbJCCJ6UyKl4re3VSf02lVJXs-MQwzDCUt2KpxxOxR0I43gOG7438AvT_qgHYMKC9x3jI1xzXw7okxrIPc6CDRPsnO8HornYmxj1UyE00LNmej9EUq-St0OUWIR2fA_cAC-w8IEQQxF8xFyFqjLBfrh1E8PoriyFarPRd_Pr-4D_86w01YRrVJDoejg3VYaZKJVP-5AYuTs6l-BNfl98mX6uxxbQBs-HTV6vMLW-6ZDg |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+Systems+Biology+Graphical+Notation&rft.jtitle=Nature+biotechnology&rft.au=Nov%C3%A8re%2C+Nicolas+Le&rft.au=Hucka%2C+Michael&rft.au=Mi%2C+Huaiyu&rft.au=Moodie%2C+Stuart&rft.date=2009-08-01&rft.issn=1087-0156&rft.eissn=1546-1696&rft.volume=27&rft.issue=8&rft.spage=735&rft.epage=741&rft_id=info:doi/10.1038%2Fnbt.1558&rft.externalDBID=n%2Fa&rft.externalDocID=10_1038_nbt_1558 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1087-0156&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1087-0156&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1087-0156&client=summon |