Mortality in adults with multidrug-resistant tuberculosis and HIV by antiretroviral therapy and tuberculosis drug use: an individual patient data meta-analysis

HIV-infection is associated with increased mortality during multidrug-resistant tuberculosis treatment, but the extent to which the use of antiretroviral therapy (ART) and anti-tuberculosis medications modify this risk are unclear. Our objective was to evaluate how use of these treatments altered mo...

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Bibliographic Details
Published in:	The Lancet (British edition) Vol. 396; no. 10248; pp. 402 - 411
Main Authors:	Bisson, Gregory P, Bastos, Mayara, Campbell, Jonathon R, Bang, Didi, Brust, James C, Isaakidis, Petros, Lange, Christoph, Menzies, Dick, Migliori, Giovanni B, Pape, Jean W, Palmero, Domingo, Baghaei, Parvaneh, Tabarsi, Payam, Viiklepp, Piret, Vilbrun, Stalz, Walsh, Jonathan, Marks, Suzanne M
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 08.08.2020 Elsevier B.V Elsevier Limited
Subjects:	Adult Adults Analysis Anti-HIV Agents - therapeutic use Antibiotics Antiretroviral agents Antiretroviral drugs Antiretroviral therapy Antitubercular agents Antitubercular Agents - therapeutic use Antiviral agents Bacilli Data analysis Datasets Death Disease control Drug resistance Drug resistance in microorganisms Drugs Female Health aspects Health risks Health services Highly active antiretroviral therapy HIV HIV (Viruses) HIV Infections - complications HIV Infections - drug therapy HIV Infections - mortality Human immunodeficiency virus Humans Infectious diseases Levofloxacin Linezolid Male Matching Meta-analysis Mortality Mortality risk Moxifloxacin Multidrug resistance Multidrug resistant organisms Regression analysis Respiration Risk Factors Sexually transmitted diseases STD Systematic review Therapy Thorax Tuberculosis Tuberculosis, Multidrug-Resistant - complications Tuberculosis, Multidrug-Resistant - drug therapy Tuberculosis, Multidrug-Resistant - mortality
ISSN:	0140-6736, 1474-547X, 1474-547X
Online Access:	Get full text
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