Improvement of Silicon Nanotweezers Sensitivity for Mechanical Characterization of Biomolecules Using Closed-Loop Control

In this paper, we show that closed-loop control can be advantageously used for the characterization of mechanical properties of biomolecules using silicon nanotweezers (SNT). SNT have already been used in open-loop mode for the characterization of mechanical properties of DNA molecules. Up to now, s...

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Bibliographic Details
Published in:	IEEE/ASME Transactions on Mechatronics Vol. 20; no. 3; pp. 1418 - 1427
Main Authors:	Lafitte, Nicolas, Haddab, Yassine, Le Gorrec, Yann, Guillou, Herve, Kumemura, Momoko, Jalabert, Laurent, Collard, Dominique, Fujita, Hiroyuki
Format:	Journal Article
Language:	English
Published:	IEEE 01.06.2015 Institute of Electrical and Electronics Engineers (IEEE) Institute of Electrical and Electronics Engineers
Subjects:	[INFO.INFO-DS]Computer Science [cs]/Data Structures and Algorithms [cs.DS] [PHYS]Physics [physics] [SPI.AUTO]Engineering Sciences [physics]/Automatic Automatic Biosensor Charge carrier processes Computer Science Data Structures and Algorithms DNA Electrodes Engineering Sciences MEMS tweezers Observers parameter detection Resonant frequency Sensitivity sensitivity improvement State feedback MEMS tweezers sensitivity improvement state feedback parameter detection Biosensor
ISSN:	1083-4435, 1941-014X
Online Access:	Get full text
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