Clinicopathological Studies on the Impact of Grape Seed Extract and L-Carnitine as Cardioprotective Agents Against Doxorubicin-Induced Toxicity in Rats

Doxorubicin (DOX) cancer therapy induces serious cardiotoxicity as a side effect. This study aimed to investigate the cardioprotective effects of grape seed extract (GSE) and L-Carnitine (L-CA) against DOX-induced cardiac toxicity in male rats. Six groups of male albino rats were used: G1 (control);...

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Bibliographic Details
Published in:	Life (Basel, Switzerland) Vol. 14; no. 12; p. 1656
Main Authors:	Aldayel, Tahany Saleh, Kilany, Omnia E., El-Hak, Heba Nageh Gad, Abdelrazek, Heba M. A., Abdallah, Osama, Omar, Donia E.
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 01.12.2024 MDPI
Subjects:	Abnormalities Antidiabetics Antioxidants Cancer Cancer therapies Cardiotoxicity Carnitine Cholesterol Doxorubicin Drug dosages Electrocardiogram Electrocardiography Enzymes Free radicals grape seed extract Grapes Health aspects Heart Hematology Inflammation L-Carnitine Laboratory animals Levocarnitine Lipid peroxidation Lipids Lipoproteins Males Medical research Oxidative stress Peroxidation Phytochemicals Plant extracts Polyphenols Seeds Toxicity Veterinary medicine China California Suez Canal L-Carnitine cardiotoxicity doxorubicin grape seed extract
ISSN:	2075-1729, 2075-1729
Online Access:	Get full text
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