Circulating IGFBP‐2: a novel biomarker for incident dementia

Objective To determine the association between plasma insulin‐like growth factor binding protein 2 (IGFBP‐2) and cognitive outcomes. Methods We measured plasma IGFBP‐2 levels in 1596 (53% women, mean age 68.7 [SD 5.7] years) dementia‐free Framingham Offspring cohort participants between 1998 and 200...

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Bibliographic Details
Published in:	Annals of clinical and translational neurology Vol. 6; no. 9; pp. 1659 - 1670
Main Authors:	McGrath, Emer R., Himali, Jayandra J., Levy, Daniel, Conner, Sarah C., DeCarli, Charles S., Pase, Matthew P., Courchesne, Paul, Satizabal, Claudia L., Vasan, Ramachandran S., Beiser, Alexa S., Seshadri, Sudha
Format:	Journal Article
Language:	English
Published:	United States John Wiley & Sons, Inc 01.09.2019 John Wiley and Sons Inc Wiley
Subjects:	Aged Alzheimer Disease - blood Alzheimer Disease - diagnosis Alzheimer Disease - epidemiology Alzheimer's disease Biomarkers Biomarkers - blood Cognitive ability Dementia Dementia - blood Dementia - diagnosis Dementia - epidemiology Female Growth factors Humans Incidence Insulin resistance Insulin-Like Growth Factor Binding Protein 3 - blood Male Metabolism Middle Aged NMR Nuclear magnetic resonance Probability Prospective Studies Proteins Risk
ISSN:	2328-9503, 2328-9503
Online Access:	Get full text
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