Roles of extracellular vesicles in the aging microenvironment and age‐related diseases

Cellular senescence is a persistently hypoproliferative state with diverse stressors in a specific aging microenvironment. Senescent cells have a double‐edged sword effect: they can be physiologically beneficial for tissue repair, organ growth, and body homeostasis, and they can be pathologically ha...

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Veröffentlicht in:	Journal of extracellular vesicles Jg. 10; H. 12; S. e12154 - n/a
Hauptverfasser:	Yin, Yujia, Chen, Huihui, Wang, Yizhi, Zhang, Ludi, Wang, Xipeng
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States John Wiley & Sons, Inc 01.10.2021 John Wiley and Sons Inc Wiley
Schlagworte:	age‐related diseases Aging Aging - genetics aging microenvironment antiaging therapy Autophagy Biosynthesis Cell cycle Cell death Cell interactions Cellular Senescence Cyclin-dependent kinases DNA damage Extracellular vesicles Extracellular Vesicles - metabolism Gene expression Homeostasis Humans Kinases Metabolism Metabolites Microenvironments Mitochondria Mutation Paracrine signalling Phosphorylation Proteins Review Senescence Signal Transduction age-related diseases aging microenvironment cellular senescence extracellular vesicles antiaging therapy
ISSN:	2001-3078, 2001-3078
Online-Zugang:	Volltext
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