How a well-adapting immune system remembers

An adaptive agent predicting the future state of an environment must weigh trust in new observations against prior experiences. In this light, we propose a view of the adaptive immune system as a dynamic Bayesian machinery that updates its memory repertoire by balancing evidence from new pathogen en...

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Bibliographic Details

Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 116; no. 18; p. 8815
Main Authors:	Mayer, Andreas, Balasubramanian, Vijay, Walczak, Aleksandra M, Mora, Thierry
Format:	Journal Article
Language:	English
Published:	United States 30.04.2019
Subjects:	Adaptation, Physiological - immunology Adaptive Immunity - physiology Animals Host-Pathogen Interactions Immunologic Memory - physiology Lymphocytes - physiology Models, Biological immune repertoire Bayesian prediction immune memory biophysics stochastic dynamics
ISSN:	1091-6490, 1091-6490
Online Access:	Get more information
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