Modulation of intrinsic inhibitory checkpoints using nano‐carriers to unleash NK cell activity

Natural killer (NK) cells provide a powerful weapon mediating immune defense against viral infections, tumor growth, and metastatic spread. NK cells demonstrate great potential for cancer immunotherapy; they can rapidly and directly kill cancer cells in the absence of MHC‐dependent antigen presentat...

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Bibliographic Details
Published in:	EMBO molecular medicine Vol. 14; no. 1; pp. e14073 - n/a
Main Authors:	Biber, Guy, Sabag, Batel, Raiff, Anat, Ben‐Shmuel, Aviad, Puthenveetil, Abhishek, Benichou, Jennifer I C, Jubany, Tammir, Levy, Moria, Killner, Shiran, Barda‐Saad, Mira
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 11.01.2022 EMBO Press John Wiley and Sons Inc Springer Nature
Subjects:	Antigen presentation Antigens Cancer Cancer immunotherapy Cbl Cytokines Cytotoxicity Efficiency EMBO03 EMBO19 Genes Humans Immune response Immune system Immunotherapy Killer Cells, Natural Ligands Liposomes Lymphocytes Major histocompatibility complex Metastases Nanoparticles Natural killer cells Neoplasms - pathology NK cells SHP‐1 Signal transduction siRNA Solid tumors Tumor Microenvironment Tumors NK cells nanoparticles SHP‐1 Cbl immunotherapy SHP-1
ISSN:	1757-4676, 1757-4684, 1757-4684
Online Access:	Get full text
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