Analytic framework for peptidomics applied to large-scale neuropeptide identification

Large-scale mass spectrometry-based peptidomics for drug discovery is relatively unexplored because of challenges in peptide degradation and identification following tissue extraction. Here we present a streamlined analytical pipeline for large-scale peptidomics. We developed an optimized sample pre...

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Bibliographic Details
Published in:Nature communications Vol. 7; no. 1; pp. 11436 - 10
Main Authors: Secher, Anna, Kelstrup, Christian D., Conde-Frieboes, Kilian W., Pyke, Charles, Raun, Kirsten, Wulff, Birgitte S., Olsen, Jesper V.
Format: Journal Article
Language:English
Published: London Nature Publishing Group UK 04.05.2016
Nature Publishing Group
Nature Portfolio
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ISSN:2041-1723, 2041-1723
Online Access:Get full text
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