Prospective Cohort of Fluvoxamine for Early Treatment of Coronavirus Disease 19

Abstract We report a real-world experience using fluvoxamine for coronavirus disease 19 (COVID-19) in a prospective cohort in the setting of a mass outbreak. Overall, 65 persons opted to receive fluvoxamine (50 mg twice daily) and 48 declined. Incidence of hospitalization was 0% (0 of 65) with fluvo...

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Vydáno v:Open forum infectious diseases Ročník 8; číslo 2; s. ofab050
Hlavní autoři: Seftel, David, Boulware, David R
Médium: Journal Article
Jazyk:angličtina
Vydáno: US Oxford University Press 01.02.2021
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ISSN:2328-8957, 2328-8957
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Abstract Abstract We report a real-world experience using fluvoxamine for coronavirus disease 19 (COVID-19) in a prospective cohort in the setting of a mass outbreak. Overall, 65 persons opted to receive fluvoxamine (50 mg twice daily) and 48 declined. Incidence of hospitalization was 0% (0 of 65) with fluvoxamine and 12.5% (6 of 48) with observation alone. At 14 days, residual symptoms persisted in 0% (0 of 65) with fluvoxamine and 60% (29 of 48) with observation. We report a real-world experience using fluvoxamine for early COVID-19. Incidence of hospitalization was 0% (0/65) with fluvoxamine and 12.5% (6/48) with observation alone. At 14 days, residual symptoms persisted in 0% (0/65) with fluvoxamine and 60% (29/48) with observation.
AbstractList We report a real-world experience using fluvoxamine for coronavirus disease 19 (COVID-19) in a prospective cohort in the setting of a mass outbreak. Overall, 65 persons opted to receive fluvoxamine (50 mg twice daily) and 48 declined. Incidence of hospitalization was 0% (0 of 65) with fluvoxamine and 12.5% (6 of 48) with observation alone. At 14 days, residual symptoms persisted in 0% (0 of 65) with fluvoxamine and 60% (29 of 48) with observation.
We report a real-world experience using fluvoxamine for coronavirus disease 19 (COVID-19) in a prospective cohort in the setting of a mass outbreak. Overall, 65 persons opted to receive fluvoxamine (50 mg twice daily) and 48 declined. Incidence of hospitalization was 0% (0 of 65) with fluvoxamine and 12.5% (6 of 48) with observation alone. At 14 days, residual symptoms persisted in 0% (0 of 65) with fluvoxamine and 60% (29 of 48) with observation. We report a real-world experience using fluvoxamine for early COVID-19. Incidence of hospitalization was 0% (0/65) with fluvoxamine and 12.5% (6/48) with observation alone. At 14 days, residual symptoms persisted in 0% (0/65) with fluvoxamine and 60% (29/48) with observation.
Abstract We report a real-world experience using fluvoxamine for coronavirus disease 19 (COVID-19) in a prospective cohort in the setting of a mass outbreak. Overall, 65 persons opted to receive fluvoxamine (50 mg twice daily) and 48 declined. Incidence of hospitalization was 0% (0 of 65) with fluvoxamine and 12.5% (6 of 48) with observation alone. At 14 days, residual symptoms persisted in 0% (0 of 65) with fluvoxamine and 60% (29 of 48) with observation. We report a real-world experience using fluvoxamine for early COVID-19. Incidence of hospitalization was 0% (0/65) with fluvoxamine and 12.5% (6/48) with observation alone. At 14 days, residual symptoms persisted in 0% (0/65) with fluvoxamine and 60% (29/48) with observation.
We report a real-world experience using fluvoxamine for coronavirus disease 19 (COVID-19) in a prospective cohort in the setting of a mass outbreak. Overall, 65 persons opted to receive fluvoxamine (50 mg twice daily) and 48 declined. Incidence of hospitalization was 0% (0 of 65) with fluvoxamine and 12.5% (6 of 48) with observation alone. At 14 days, residual symptoms persisted in 0% (0 of 65) with fluvoxamine and 60% (29 of 48) with observation.We report a real-world experience using fluvoxamine for coronavirus disease 19 (COVID-19) in a prospective cohort in the setting of a mass outbreak. Overall, 65 persons opted to receive fluvoxamine (50 mg twice daily) and 48 declined. Incidence of hospitalization was 0% (0 of 65) with fluvoxamine and 12.5% (6 of 48) with observation alone. At 14 days, residual symptoms persisted in 0% (0 of 65) with fluvoxamine and 60% (29 of 48) with observation.
Author Seftel, David
Boulware, David R
AuthorAffiliation 1 Golden Gate Fields Medical Clinic , Berkeley, California, USA
3 University of Minnesota Medical School , Minneapolis, Minnesota, USA
2 Enable Biosciences Inc , South San Francisco, California, USA
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– name: 3 University of Minnesota Medical School , Minneapolis, Minnesota, USA
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/33623808$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1001/jama.2020.22760
10.1126/scitranslmed.aau5266
10.1161/CIRCULATIONAHA.120.051718
ContentType Journal Article
Copyright The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. 2021
The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America.
The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
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Keywords COVID-19
cohort
coronavirus
fluvoxamine
SARS-COV-2
Language English
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References Rosen (2021021717275727400_CIT0002) 2019; 11
Franklin (2021021717275727400_CIT0003) 2020
Lenze (2021021717275727400_CIT0001) 2020; 324
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  year: 2020
  ident: 2021021717275727400_CIT0001
  article-title: Fluvoxamine vs placebo and clinical deterioration in outpatients with symptomatic covid-19: a randomized clinical trial
  publication-title: JAMA
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– volume: 11
  start-page: eaau5266
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  publication-title: Circulation
  doi: 10.1161/CIRCULATIONAHA.120.051718
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Snippet Abstract We report a real-world experience using fluvoxamine for coronavirus disease 19 (COVID-19) in a prospective cohort in the setting of a mass outbreak....
We report a real-world experience using fluvoxamine for coronavirus disease 19 (COVID-19) in a prospective cohort in the setting of a mass outbreak. Overall,...
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Title Prospective Cohort of Fluvoxamine for Early Treatment of Coronavirus Disease 19
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