A multi-omics study of circulating phospholipid markers of blood pressure

High-throughput techniques allow us to measure a wide-range of phospholipids which can provide insight into the mechanisms of hypertension. We aimed to conduct an in-depth multi-omics study of various phospholipids with systolic blood pressure (SBP) and diastolic blood pressure (DBP). The associatio...

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Veröffentlicht in:	Scientific reports Jg. 12; H. 1; S. 574 - 13
Hauptverfasser:	Liu, Jun, de Vries, Paul S., Del Greco M., Fabiola, Johansson, Åsa, Schraut, Katharina E., Hayward, Caroline, van Dijk, Ko Willems, Franco, Oscar. H., Hicks, Andrew A., Vitart, Veronique, Rudan, Igor, Campbell, Harry, Polašek, Ozren, Pramstaller, Peter P., Wilson, James F., Gyllensten, Ulf, van Duijn, Cornelia M., Dehghan, Abbas, Demirkan, Ayşe
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 12.01.2022 Nature Publishing Group Nature Portfolio
Schlagworte:	631/114/2401 631/92/320 631/92/608 692/308/174 692/4019/592/75/243 692/499 Adult Aged Biomarkers - blood Blood Pressure Body mass index Cardiometabolic Risk Factors Cohort Studies Computational Biology Diabetes Diabetes mellitus (non-insulin dependent) Diastole Female Heart rate Humanities and Social Sciences Humans Hypertension Hypertension - blood Insulin Insulin resistance Ionization Leptin Lipoproteins Male Mass spectrometry Mass spectroscopy Mendelian Randomization Analysis Metabolites Middle Aged multidisciplinary Phosphatidylethanolamine Phospholipids Phospholipids - blood Regression analysis Science Science (multidisciplinary) Systole Triglycerides HERITABILITY TRAIT METABOLITES CHOLINE ADIPONECTIN QUANTIFICATION SPHINGOMYELIN GENOME-WIDE ASSOCIATIONHIGH-THROUGHPUT HYPERTENSION SPHOSPHATIDYL
ISSN:	2045-2322, 2045-2322
Online-Zugang:	Volltext
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