Intraoperative prediction of cardiac surgery-associated acute kidney injury using urinary biomarkers of cell cycle arrest

Tissue inhibitor of metalloproteinases 2 (TIMP-2) and insulin-like growth factor-binding protein 7 (IGFBP7) are postoperative urinary biomarkers of renal stress and acute kidney injury (AKI). We conducted this study to test the hypothesis that intraoperative concentrations of urinary [TIMP-2]·[IGFBP...

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Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery Jg. 157; H. 4; S. 1545
Hauptverfasser:	Cummings, Jared J, Shaw, Andrew D, Shi, Jing, Lopez, Marcos G, O'Neal, Jason B, Billings, 4th, Frederic T
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.04.2019
Schlagworte:	Acute Kidney Injury - diagnosis Acute Kidney Injury - etiology Acute Kidney Injury - urine Aged Biomarkers - urine Cardiac Surgical Procedures - adverse effects Cell Cycle Checkpoints Female Humans Insulin-Like Growth Factor Binding Proteins - urine Intraoperative Period Male Middle Aged Predictive Value of Tests Prospective Studies Randomized Controlled Trials as Topic Risk Assessment Risk Factors Time Factors Tissue Inhibitor of Metalloproteinase-2 - urine Treatment Outcome Up-Regulation Urinalysis cardiac surgery TIMP-2 IGFBP7 acute kidney injury biomarker NephroCheck, prediction
ISSN:	1097-685X, 1097-685X
Online-Zugang:	Weitere Angaben
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