CASSIS and SMIPS: promoter-based prediction of secondary metabolite gene clusters in eukaryotic genomes

Motivation: Secondary metabolites (SM) are structurally diverse natural products of high pharmaceutical importance. Genes involved in their biosynthesis are often organized in clusters, i.e., are co-localized and co-expressed. In silico cluster prediction in eukaryotic genomes remains problematic ma...

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Bibliographic Details

Published in:	Bioinformatics Vol. 32; no. 8; pp. 1138 - 1143
Main Authors:	Wolf, Thomas, Shelest, Vladimir, Nath, Neetika, Shelest, Ekaterina
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 15.04.2016
Subjects:	Anchors Bioinformatics Clusters Eukaryota Genes Genomes Islands Metabolites Multigene Family Original Papers Peptide Synthases - genetics Polyketide Synthases - genetics Searching Software
ISSN:	1367-4803, 1367-4811, 1460-2059
Online Access:	Get full text
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