tcR: an R package for T cell receptor repertoire advanced data analysis

Background The Immunoglobulins (IG) and the T cell receptors (TR) play the key role in antigen recognition during the adaptive immune response. Recent progress in next-generation sequencing technologies has provided an opportunity for the deep T cell receptor repertoire profiling. However, a special...

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Veröffentlicht in:	BMC bioinformatics Jg. 16; H. 1; S. 175
Hauptverfasser:	Nazarov, Vadim I., Pogorelyy, Mikhail V., Komech, Ekaterina A., Zvyagin, Ivan V., Bolotin, Dmitry A., Shugay, Mikhail, Chudakov, Dmitry M., Lebedev, Yury B., Mamedov, Ilgar Z.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BioMed Central 28.05.2015 BioMed Central Ltd
Schlagworte:	Algorithms Analysis Bioinformatics Biomedical and Life Sciences Computational Biology/Bioinformatics Computer Appl. in Life Sciences High-Throughput Nucleotide Sequencing - methods Humans Immune response Immunoglobulins - genetics Life Sciences Microarrays Physiological aspects Programming Languages Receptors, Antigen, T-Cell - genetics Receptors, Antigen, T-Cell - immunology Sequence analysis (Applications) Sequence Analysis, DNA - methods Software T cells TR diversity Adaptive immunity T cell receptor TR repertoire analysis
ISSN:	1471-2105, 1471-2105
Online-Zugang:	Volltext
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