Transforming insect population control with precision guided sterile males with demonstration in flies

The sterile insect technique (SIT) is an environmentally safe and proven technology to suppress wild populations. To further advance its utility, a novel CRISPR-based technology termed precision guided SIT (pgSIT) is described. PgSIT mechanistically relies on a dominant genetic technology that enabl...

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Bibliographic Details
Published in:	Nature communications Vol. 10; no. 1; pp. 84 - 12
Main Authors:	Kandul, Nikolay P., Liu, Junru, Sanchez C., Hector M., Wu, Sean L., Marshall, John M., Akbari, Omar S.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 08.01.2019 Nature Publishing Group Nature Portfolio
Subjects:	38/23 38/44 38/70 45/23 45/29 45/41 45/77 631/208/4041/3196 631/61/338/552 64/24 Animals Biotechnology CRISPR CRISPR-Cas Systems - genetics Disease control Drosophila - genetics Drosophila - physiology Efficiency Eggs Female Females Fertility Fruit flies Gene Editing - methods Genome, Insect - genetics Genomes Humanities and Social Sciences Infertility Insect control Insect Vectors - genetics Insect Vectors - physiology Insects Life Sciences Male Male sterility Males Mathematical analysis Mathematical models Models, Biological multidisciplinary Pest control Pest Control, Biological - methods Pests Population Population control Population Control - methods RNA, Guide, CRISPR-Cas Systems - genetics Science Science (multidisciplinary) Sexing Sexual Behavior, Animal Stability Sterilization Sterilized organisms Vectors Vectors (mathematics) X chromosomes
ISSN:	2041-1723, 2041-1723
Online Access:	Get full text
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