Small RNAs containing the pathogenic determinant of a chloroplast‐replicating viroid guide the degradation of a host mRNA as predicted by RNA silencing

Summary How viroids, tiny non‐protein‐coding RNAs (∼250–400 nt), incite disease is unclear. One hypothesis is that viroid‐derived small RNAs (vd‐sRNAs; 21–24 nt) resulting from the host defensive response, via RNA silencing, may target for cleavage cell mRNAs and trigger a signal cascade, eventually...

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Vydáno v:	The Plant journal : for cell and molecular biology Ročník 70; číslo 6; s. 991 - 1003
Hlavní autoři:	Navarro, Beatriz, Gisel, Andreas, Rodio, Maria Elena, Delgado, Sonia, Flores, Ricardo, Di Serio, Francesco
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Oxford, UK Blackwell Publishing Ltd 01.06.2012 Blackwell
Témata:	abnormal development albino Arabidopsis Base Sequence Biological and medical sciences cell cleavage Cell differentiation, maturation, development, hematopoiesis Cell physiology chloroplast development Chloroplasts Chloroplasts - virology Cloning complementary DNA Fruits Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation, Plant genes genetics Heat shock proteins heat‐shock protein 90 hosts leaves messenger RNA metabolism Molecular and cellular biology Molecular Sequence Data Mutagenesis, Insertional non‐coding RNAs Nucleic Acid Conformation Peach latent mosaic viroid peaches Plant Diseases Plant Diseases - genetics Plant Diseases - virology Plant pathology Plant physiology and development PLMVd prediction progeny proteins Prunus Prunus - genetics Prunus - virology Prunus persica rapid amplification of cDNA ends Ribonucleic acid RNA RNA Interference RNA silencing RNA Stability RNA, Messenger RNA, Messenger - genetics RNA, Messenger - metabolism RNA, Viral RNA, Viral - genetics Seedlings Sequence Analysis, RNA signal transduction transposons viroid pathogenesis viroids Viroids - genetics virology Pathogenesis viroid pathogenesis Host RNA silencing Virus Degradation Messenger RNA heat-shock protein 90 PLMVd Pathogenic Viroid non-coding RNAs Heat shock protein Non coding RNA Development Chloroplast chloroplast development
ISSN:	0960-7412, 1365-313X, 1365-313X
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