Non-pharmacological interventions for methamphetamine use disorder: a systematic review

•Non pharmacological interventions are effective in treating METH use disorder.•Contingency management and cognitive behavioural therapy yield better outcomes.•Heterogeneity noted across the studies in terms of methodology and interpretation.•The methodology should be standardised to allow compariso...

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Published in:Drug and alcohol dependence Vol. 212; p. 108060
Main Authors: AshaRani, PV, Hombali, Aditi, Seow, Esmond, Ong, Wei Jie, Tan, Jit Hui, Subramaniam, Mythily
Format: Journal Article
Language:English
Published: Ireland Elsevier B.V 01.07.2020
Elsevier Science Ltd
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ISSN:0376-8716, 1879-0046, 1879-0046
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Abstract •Non pharmacological interventions are effective in treating METH use disorder.•Contingency management and cognitive behavioural therapy yield better outcomes.•Heterogeneity noted across the studies in terms of methodology and interpretation.•The methodology should be standardised to allow comparison across the studies. Methamphetamine (METH) use is on the rise globally, with the number of treatment seekers increasing exponentially across the globe. Evidence-based therapies are needed to meet rising treatment needs. This systematic review intends to appraise the existing evidence to identify effective non-pharmaceutical approaches for the treatment of METH use disorder. Five electronic bibliographic databases-Ovid (Medline), Embase, Cumulative Index of Nursing and Allied Health Literature (CINAHL), Web of Science and PsycINFO- were searched to identify relevant studies that were published between January 1995 to February 2020. Studies were selected and assessed by two independent reviewers. A systematic review of data from both randomised control trials (RCT) and non-RCTs was conducted to appraise the evidence. A total of 44 studies were included in the review. Behavioural interventions, i.e. cognitive behavioural therapy (CBT), contingency management (CM), exercise, residential rehabilitation based therapies, repetitive transcranial magnetic stimulation (rTMS), and matrix model demonstrated treatment efficacy in promoting abstinence, reducing methamphetamine use or craving in the participants. While CM interventions showed the strongest evidence favouring the outcomes assessed, tailored CBT alone or with CM was also effective in the target population. Behavioural interventions should be considered as the first line of treatment for methamphetamine use disorder. Future studies should address the longevity of the effects, and limitations due to smaller sample sizes and high dropout rates to enable better assessment of evidence.
AbstractList Methamphetamine (METH) use is on the rise globally, with the number of treatment seekers increasing exponentially across the globe. Evidence-based therapies are needed to meet rising treatment needs. This systematic review intends to appraise the existing evidence to identify effective non-pharmaceutical approaches for the treatment of METH use disorder. Five electronic bibliographic databases-Ovid (Medline), Embase, Cumulative Index of Nursing and Allied Health Literature (CINAHL), Web of Science and PsycINFO- were searched to identify relevant studies that were published between January 1995 to February 2020. Studies were selected and assessed by two independent reviewers. A systematic review of data from both randomised control trials (RCT) and non-RCTs was conducted to appraise the evidence. A total of 44 studies were included in the review. Behavioural interventions, i.e. cognitive behavioural therapy (CBT), contingency management (CM), exercise, residential rehabilitation based therapies, repetitive transcranial magnetic stimulation (rTMS), and matrix model demonstrated treatment efficacy in promoting abstinence, reducing methamphetamine use or craving in the participants. While CM interventions showed the strongest evidence favouring the outcomes assessed, tailored CBT alone or with CM was also effective in the target population. Behavioural interventions should be considered as the first line of treatment for methamphetamine use disorder. Future studies should address the longevity of the effects, and limitations due to smaller sample sizes and high dropout rates to enable better assessment of evidence.
Methamphetamine (METH) use is on the rise globally, with the number of treatment seekers increasing exponentially across the globe. Evidence-based therapies are needed to meet rising treatment needs. This systematic review intends to appraise the existing evidence to identify effective non-pharmaceutical approaches for the treatment of METH use disorder.BACKGROUNDMethamphetamine (METH) use is on the rise globally, with the number of treatment seekers increasing exponentially across the globe. Evidence-based therapies are needed to meet rising treatment needs. This systematic review intends to appraise the existing evidence to identify effective non-pharmaceutical approaches for the treatment of METH use disorder.Five electronic bibliographic databases-Ovid (Medline), Embase, Cumulative Index of Nursing and Allied Health Literature (CINAHL), Web of Science and PsycINFO- were searched to identify relevant studies that were published between January 1995 to February 2020. Studies were selected and assessed by two independent reviewers. A systematic review of data from both randomised control trials (RCT) and non-RCTs was conducted to appraise the evidence.METHODSFive electronic bibliographic databases-Ovid (Medline), Embase, Cumulative Index of Nursing and Allied Health Literature (CINAHL), Web of Science and PsycINFO- were searched to identify relevant studies that were published between January 1995 to February 2020. Studies were selected and assessed by two independent reviewers. A systematic review of data from both randomised control trials (RCT) and non-RCTs was conducted to appraise the evidence.A total of 44 studies were included in the review. Behavioural interventions, i.e. cognitive behavioural therapy (CBT), contingency management (CM), exercise, residential rehabilitation based therapies, repetitive transcranial magnetic stimulation (rTMS), and matrix model demonstrated treatment efficacy in promoting abstinence, reducing methamphetamine use or craving in the participants. While CM interventions showed the strongest evidence favouring the outcomes assessed, tailored CBT alone or with CM was also effective in the target population.RESULTSA total of 44 studies were included in the review. Behavioural interventions, i.e. cognitive behavioural therapy (CBT), contingency management (CM), exercise, residential rehabilitation based therapies, repetitive transcranial magnetic stimulation (rTMS), and matrix model demonstrated treatment efficacy in promoting abstinence, reducing methamphetamine use or craving in the participants. While CM interventions showed the strongest evidence favouring the outcomes assessed, tailored CBT alone or with CM was also effective in the target population.Behavioural interventions should be considered as the first line of treatment for methamphetamine use disorder. Future studies should address the longevity of the effects, and limitations due to smaller sample sizes and high dropout rates to enable better assessment of evidence.CONCLUSIONSBehavioural interventions should be considered as the first line of treatment for methamphetamine use disorder. Future studies should address the longevity of the effects, and limitations due to smaller sample sizes and high dropout rates to enable better assessment of evidence.
Background: Methamphetamine (METH) use is on the rise globally, with the number of treatment seekers increasing exponentially across the globe. Evidence-based therapies are needed to meet rising treatment needs. This systematic review intends to appraise the existing evidence to identify effective non-pharmaceutical approaches for the treatment of METH use disorder. Methods: Five electronic bibliographic databases-Ovid (Medline), Embase, Cumulative Index of Nursing and Allied Health Literature (CINAHL), Web of Science and PsycINFO- were searched to identify relevant studies that were published between January 1995 to February 2020. Studies were selected and assessed by two independent reviewers. A systematic review of data from both randomised control trials (RCT) and non-RCTs was conducted to appraise the evidence. Results: A total of 44 studies were included in the review. Behavioural interventions, i.e. cognitive behavioural therapy (CBT), contingency management (CM), exercise, residential rehabilitation based therapies, repetitive transcranial magnetic stimulation (rTMS), and matrix model demonstrated treatment efficacy in promoting abstinence, reducing methamphetamine use or craving in the participants. While CM interventions showed the strongest evidence favouring the outcomes assessed, tailored CBT alone or with CM was also effective in the target population. Conclusions: Behavioural interventions should be considered as the first line of treatment for methamphetamine use disorder. Future studies should address the longevity of the effects, and limitations due to smaller sample sizes and high dropout rates to enable better assessment of evidence.
•Non pharmacological interventions are effective in treating METH use disorder.•Contingency management and cognitive behavioural therapy yield better outcomes.•Heterogeneity noted across the studies in terms of methodology and interpretation.•The methodology should be standardised to allow comparison across the studies. Methamphetamine (METH) use is on the rise globally, with the number of treatment seekers increasing exponentially across the globe. Evidence-based therapies are needed to meet rising treatment needs. This systematic review intends to appraise the existing evidence to identify effective non-pharmaceutical approaches for the treatment of METH use disorder. Five electronic bibliographic databases-Ovid (Medline), Embase, Cumulative Index of Nursing and Allied Health Literature (CINAHL), Web of Science and PsycINFO- were searched to identify relevant studies that were published between January 1995 to February 2020. Studies were selected and assessed by two independent reviewers. A systematic review of data from both randomised control trials (RCT) and non-RCTs was conducted to appraise the evidence. A total of 44 studies were included in the review. Behavioural interventions, i.e. cognitive behavioural therapy (CBT), contingency management (CM), exercise, residential rehabilitation based therapies, repetitive transcranial magnetic stimulation (rTMS), and matrix model demonstrated treatment efficacy in promoting abstinence, reducing methamphetamine use or craving in the participants. While CM interventions showed the strongest evidence favouring the outcomes assessed, tailored CBT alone or with CM was also effective in the target population. Behavioural interventions should be considered as the first line of treatment for methamphetamine use disorder. Future studies should address the longevity of the effects, and limitations due to smaller sample sizes and high dropout rates to enable better assessment of evidence.
ArticleNumber 108060
Author Seow, Esmond
Tan, Jit Hui
Hombali, Aditi
Subramaniam, Mythily
AshaRani, PV
Ong, Wei Jie
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  givenname: Mythily
  surname: Subramaniam
  fullname: Subramaniam, Mythily
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Keywords abstinence
Non-pharmacological interventions
Methamphetamine use disorder
Methamphetamine
Language English
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– name: Lausanne
PublicationTitle Drug and alcohol dependence
PublicationTitleAlternate Drug Alcohol Depend
PublicationYear 2020
Publisher Elsevier B.V
Elsevier Science Ltd
Publisher_xml – name: Elsevier B.V
– name: Elsevier Science Ltd
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Snippet •Non pharmacological interventions are effective in treating METH use disorder.•Contingency management and cognitive behavioural therapy yield better...
Methamphetamine (METH) use is on the rise globally, with the number of treatment seekers increasing exponentially across the globe. Evidence-based therapies...
Background: Methamphetamine (METH) use is on the rise globally, with the number of treatment seekers increasing exponentially across the globe. Evidence-based...
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StartPage 108060
SubjectTerms abstinence
Amphetamine-Related Disorders - psychology
Amphetamine-Related Disorders - therapy
Amphetamines
Appraisal
Behavior
Behavior Therapy - methods
Cognitive ability
Cognitive aspects
Cognitive behavioral therapy
Cognitive Behavioral Therapy - methods
Cognitive-behavioral factors
Contingency
Contingency learning
Craving
Disorders
Dropping out
Efficacy
Evaluation
Exercise - physiology
Exercise - psychology
Health services utilization
Help seeking behavior
Humans
Intervention
Magnetic fields
Methamphetamine
Methamphetamine - adverse effects
Methamphetamine use disorder
Non-pharmacological intervention
Non-pharmacological interventions
Nursing
Randomized Controlled Trials as Topic - methods
Rehabilitation
Residential care
Systematic review
Therapy
Transcranial magnetic stimulation
Treatment needs
Treatment Outcome
Title Non-pharmacological interventions for methamphetamine use disorder: a systematic review
URI https://www.clinicalkey.com/#!/content/1-s2.0-S0376871620302258
https://dx.doi.org/10.1016/j.drugalcdep.2020.108060
https://www.ncbi.nlm.nih.gov/pubmed/32445927
https://www.proquest.com/docview/2434256880
https://www.proquest.com/docview/2406307655
Volume 212
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