Use of a high platelet-to-RBC ratio of 2:1 is more effective in correcting trauma-induced coagulopathy than a ratio of 1:1 in a rat multiple trauma transfusion model

Background Platelet dysfunction importantly contributes to trauma-induced coagulopathy (TIC). Our aim was to examine the impact of transfusing platelets (PLTs) in a 2:1 PLT-to-red blood cell (RBC) ratio versus the standard 1:1 ratio on transfusion requirements, correction of TIC, and organ damage in...

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Bibliographic Details
Published in:	Intensive care medicine experimental Vol. 7; no. Suppl 1; pp. 42 - 12
Main Authors:	Kleinveld, Derek J. B., Wirtz, Mathijs R., van den Brink, Daan P., Maas, M. Adrie W., Roelofs, Joris J. T. H., Goslings, J. Carel, Hollmann, Markus W., Juffermans, Nicole P.
Format:	Journal Article
Language:	English
Published:	Cham Springer International Publishing 25.07.2019 Springer Nature B.V SpringerOpen
Subjects:	Blood platelets Blood transfusions Coagulation Coagulopathy Critical Care Medicine Experimental Hemorrhage Histopathology Intensive Intensive care Medicine Medicine & Public Health Platelets Rodents Transfusion Trauma Transfusion Platelets Trauma Experimental Coagulopathy
ISSN:	2197-425X, 2197-425X
Online Access:	Get full text
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