Variability and reproducibility in deep learning for medical image segmentation

Medical image segmentation is an important tool for current clinical applications. It is the backbone of numerous clinical diagnosis methods, oncological treatments and computer-integrated surgeries. A new class of machine learning algorithm, deep learning algorithms, outperforms the results of clas...

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Bibliographic Details
Published in:Scientific reports Vol. 10; no. 1; p. 13724
Main Authors: Renard, Félix, Guedria, Soulaimane, Palma, Noel De, Vuillerme, Nicolas
Format: Journal Article
Language:English
Published: London Nature Publishing Group UK 13.08.2020
Nature Publishing Group
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ISSN:2045-2322, 2045-2322
Online Access:Get full text
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Summary:Medical image segmentation is an important tool for current clinical applications. It is the backbone of numerous clinical diagnosis methods, oncological treatments and computer-integrated surgeries. A new class of machine learning algorithm, deep learning algorithms, outperforms the results of classical segmentation in terms of accuracy. However, these techniques are complex and can have a high range of variability, calling the reproducibility of the results into question. In this article, through a literature review, we propose an original overview of the sources of variability to better understand the challenges and issues of reproducibility related to deep learning for medical image segmentation. Finally, we propose 3 main recommendations to address these potential issues: (1) an adequate description of the framework of deep learning, (2) a suitable analysis of the different sources of variability in the framework of deep learning, and (3) an efficient system for evaluating the segmentation results.
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PMCID: PMC7426407
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-69920-0