Ferroptosis: molecular mechanisms and health implications

Cell death can be executed through different subroutines. Since the description of ferroptosis as an iron-dependent form of non-apoptotic cell death in 2012, there has been mounting interest in the process and function of ferroptosis. Ferroptosis can occur through two major pathways, the extrinsic o...

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Bibliographic Details
Published in:	Cell research Vol. 31; no. 2; pp. 107 - 125
Main Authors:	Tang, Daolin, Chen, Xin, Kang, Rui, Kroemer, Guido
Format:	Journal Article
Language:	English
Published:	Singapore Springer Singapore 01.02.2021 Nature Publishing Group
Subjects:	38 631/337 631/80 Animals Antioxidants Antioxidants - metabolism Apoptosis Autophagy Biochemistry, Molecular Biology Biomedical and Life Sciences Cancer Cell Biology Cell death Cellular Biology Epigenesis, Genetic Epigenetics Ferroptosis Ferroptosis - genetics Ferroptosis - immunology Free radicals Humans Inflammation Iron - metabolism Life Sciences Lipid Peroxidation Lipids Molecular machines Molecular modelling Mortality Neoplasms - metabolism Neurodegeneration NF-E2-Related Factor 2 Oxidants Oxidation Oxidizing agents Phagocytosis Post-transcription Reactive Oxygen Species - metabolism Review Review Article Signal Transduction
ISSN:	1001-0602, 1748-7838, 1748-7838
Online Access:	Get full text
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