CDH17 Is a More Sensitive Marker for Gastric Adenocarcinoma Than CK20 and CDX2

Context.— CDH17, which is expressed in the intestinal epithelium, is a novel oncogene involved in tumor invasion and metastasis. A panel consisting of cytokeratin (CK) 7, CD20, and CDX2 antibodies is typically used to diagnose gastrointestinal adenocarcinomas. However, studies have shown that CDH17...

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Veröffentlicht in:	Archives of pathology & laboratory medicine (1976) Jg. 141; H. 1; S. 144 - 150
Hauptverfasser:	Altree-Tacha, David, Tyrrell, Jillian, Haas, Thomas
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States College of American Pathologists 01.01.2017
Schlagworte:	Adenocarcinoma Adenocarcinoma - diagnosis Adenocarcinoma - metabolism Biomarkers, Tumor - analysis Cadherins - analysis Care and treatment CDX2 Transcription Factor - analysis Diagnosis Fixatives Formaldehyde Genetic aspects Health aspects Humans Immunohistochemistry - methods Immunohistochemistry - statistics & numerical data Innovations Keratin-20 - analysis Membrane proteins Molecular diagnostic techniques Paraffin Embedding Sensitivity and Specificity Stomach cancer Stomach Neoplasms - diagnosis Stomach Neoplasms - metabolism Tissue Array Analysis - methods Tissue Array Analysis - statistics & numerical data Tissue Fixation
ISSN:	0003-9985, 1543-2165, 1543-2165
Online-Zugang:	Volltext
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