Folate-vitamin B-12 interaction in relation to cognitive impairment, anemia, and biochemical indicators of vitamin B-12 deficiency

Previous reports on pernicious anemia treatment suggested that high folic acid intake adversely influences the natural history of vitamin B-12 deficiency, which affects many elderly individuals. However, experimental investigation of this hypothesis is unethical, and the few existing observational d...

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Bibliographic Details
Published in:	The American journal of clinical nutrition Vol. 89; no. 2; p. 702S
Main Authors:	Selhub, Jacob, Morris, Martha Savaria, Jacques, Paul F, Rosenberg, Irwin H
Format:	Journal Article
Language:	English
Published:	United States 01.02.2009
Subjects:	5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase - metabolism Aging - blood Anemia, Pernicious - blood Anemia, Pernicious - diagnosis Anemia, Pernicious - epidemiology Cognition Disorders - blood Cognition Disorders - diagnosis Cognition Disorders - epidemiology Drug Interactions Female Folic Acid - administration & dosage Folic Acid - blood Homocysteine - blood Humans Male Methylmalonic Acid - blood Methylmalonyl-CoA Mutase - metabolism Middle Aged Nutrition Surveys Nutritional Status Odds Ratio Prevalence Vitamin B 12 - administration & dosage Vitamin B 12 - blood Vitamin B 12 Deficiency - blood Vitamin B 12 Deficiency - diagnosis Vitamin B 12 Deficiency - epidemiology
ISSN:	1938-3207, 1938-3207
Online Access:	Get more information
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