A novel variant marking HLA-DP expression levels predicts recovery from hepatitis B virus infection

Variants near the HLA-DP gene show the strongest genome-wide association with chronic hepatitis B virus (HBV) infection and HBV recovery/persistence in Asians. To test the effect of the HLA-DP region on outcomes to HBV infection, we sequenced the polymorphic HLA-DPB1 and DPA1 coding exons and the co...

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Veröffentlicht in:	Journal of virology Jg. 86; H. 12; S. 6979
Hauptverfasser:	Thomas, Rasmi, Thio, Chloe L, Apps, Richard, Qi, Ying, Gao, Xiaojiang, Marti, Darlene, Stein, Judy L, Soderberg, Kelly A, Moody, M Anthony, Goedert, James J, Kirk, Gregory D, Hoots, W Keith, Wolinsky, Steven, Carrington, Mary
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.06.2012
Schlagworte:	Cohort Studies Genetic Variation Genome-Wide Association Study Hepatitis B - genetics Hepatitis B virus - physiology HLA-DP alpha-Chains - genetics HLA-DP beta-Chains - genetics Humans Racial Groups - genetics
ISSN:	1098-5514, 1098-5514
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