Gestational Diseases — A Workshop Report

Between 11% and 20% of all clinically recognised pregnancies are lost before the 20th week of gestation, with huge financial and personal implications. Immune mechanisms have been proposed to play a role in unexplained recurrent miscarriage. Considerable attention has focused on endometrial leucocyt...

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Vydáno v:	Placenta (Eastbourne) Ročník 29; s. 92 - 94
Hlavní autoři:	Lash, G.E., Quenby, S., Burton, G.J., Nakashima, A., Kamat, B.R., Ray, J., Bulmer, J.N.
Médium:	Journal Article Konferenční příspěvek
Jazyk:	angličtina
Vydáno:	Oxford Elsevier Ltd 01.03.2008 Elsevier
Témata:	Abortion, Spontaneous - immunology Abortion, Spontaneous - metabolism Abortion, Spontaneous - pathology Biological and medical sciences Education Embryology: invertebrates and vertebrates. Teratology Female Fundamental and applied biological sciences. Psychology Humans Hydatidiform mole Hydatidiform Mole - immunology Hydatidiform Mole - metabolism Hydatidiform Mole - pathology Internal Medicine Miscarriage Obstetrics and Gynecology Oxidative Stress Pregnancy Proliferation Uterine natural killer cells Uterus - immunology Uterus - metabolism Uterus - pathology Oxidative stress Proliferation Hydatidiform mole Miscarriage Uterine natural killer cells Pregnancy Vertebrata Mammalia
ISSN:	0143-4004, 1532-3102
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Popis
Shrnutí:	Between 11% and 20% of all clinically recognised pregnancies are lost before the 20th week of gestation, with huge financial and personal implications. Immune mechanisms have been proposed to play a role in unexplained recurrent miscarriage. Considerable attention has focused on endometrial leucocyte populations in recurrent miscarriage, although the underlying pathogenesis remains largely unexplained. The mechanisms underlying sporadic miscarriage are even less well understood, although aneuploidy is the commonest attributable cause of early (≤12 completed weeks gestation) sporadic miscarriage. Hydatidiform mole is a rare cause of early pregnancy loss with marked geographical variation in incidence. Both complete and partial hydatidiform mole are associated with excessive trophoblast proliferation and hence provide an opportunity to study trophoblast growth regulation.
Bibliografie:	SourceType-Scholarly Journals-1 ObjectType-News-1 ObjectType-Feature-4 ObjectType-Conference-2 content type line 23 ObjectType-Article-3
ISSN:	0143-4004 1532-3102
DOI:	10.1016/j.placenta.2007.10.004