Overview of hepatitis B viral replication and genetic variability

Chronic infection with hepatitis B virus (HBV) greatly increases the risk for liver cirrhosis and hepatocellular carcinoma (HCC). HBV isolates worldwide can be divided into ten genotypes. Moreover, the immune clearance phase selects for mutations in different parts of the viral genome. The outcome o...

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Bibliographic Details

Published in:	Journal of hepatology Vol. 64; no. 1; pp. S4 - S16
Main Authors:	Tong, Shuping, Revill, Peter
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.04.2016
Subjects:	DNA, Viral - genetics Gastroenterology and Hepatology Genome, Viral HBV Hepatitis B - virology Hepatitis B virus - genetics Humans Mutation Promoter Regions, Genetic Replication Variability Replication HBV Variability
ISSN:	0168-8278, 1600-0641, 1600-0641
Online Access:	Get full text
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