Distinct Actions of Insulin-Like Growth Factors (IGFs) on Placental Development and Fetal Growth: Lessons from Mice and Guinea Pigs

Placental insufficiency is thought to be a key factor in many cases of intrauterine growth restriction which complicates about 6% of pregnancies in western countries. Understanding the molecular control of placental and fetal growth is essential to identifying diagnostic and therapeutic targets to i...

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Vydané v:	Placenta (Eastbourne) Ročník 29; s. 42 - 47
Hlavní autori:	Roberts, C.T., Owens, J.A., Sferruzzi-Perri, A.N.
Médium:	Journal Article Konferenčný príspevok..
Jazyk:	English
Vydavateľské údaje:	Oxford Elsevier Ltd 01.03.2008 Elsevier
Predmet:	Animals Biological and medical sciences Embryology: invertebrates and vertebrates. Teratology Female Fetal Development - physiology Fetal growth Fundamental and applied biological sciences. Psychology Guinea Pigs Humans IGF-I IGF-II IGF2R Insulin-Like Growth Factor I - physiology Insulin-Like Growth Factor II - physiology Internal Medicine Mice Obstetrics and Gynecology Placenta - physiology Placental transport Pregnancy Receptor, IGF Type 1 - physiology Receptor, IGF Type 2 - physiology Trophoblast invasion Fetal growth Placental transport IGF-I Trophoblast invasion IGF2R IGF-II Vertebrata Fetal development Insulin like growth factor Guinea pig Mammalia Placenta Mouse Fetal membrane Growth Animal Rodentia
ISSN:	0143-4004, 1532-3102
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