Dysfunction of Protein Quality Control in Parkinsonism–Dementia Complex of Guam

Guam parkinsonism-dementia complex (G-PDC) is an enigmatic neurodegenerative disease that is endemic to the Pacific island of Guam. G-PDC patients are clinically characterized by progressive cognitive impairment and parkinsonism. Neuropathologically, G-PDC is characterized by abundant neurofibrillar...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Frontiers in neurology Jg. 9; S. 173
Hauptverfasser:	Verheijen, Bert M., Oyanagi, Kiyomitsu, van Leeuwen, Fred W.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland Frontiers Media S.A 20.03.2018
Schlagworte:	Guam parkinsonism–dementia complex mutant ubiquitin neurofibrillary tangles Neuroscience protein aggregation protein quality control tau mutant ubiquitin Guam parkinsonism–dementia complex protein aggregation neurofibrillary tangles protein quality control tau 43-kDa TAR DNA-binding protein neuropathology
ISSN:	1664-2295, 1664-2295
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!