Stereotactic ablative radiation for pancreatic cancer on a 1.5 Telsa magnetic resonance-linac system
•Ablative radiation therapy (A-RT) is effective for locally advanced pancreas cancer.•30 patients received A-RT using diagnostic quality MR-adaptive treatment delivery.•Cumulative incidences of 1-year local and distant progression were 19.3% and 47.4%•Overall and progression-free survival 1-year fro...
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| Vydané v: | Physics and imaging in radiation oncology Ročník 24; s. 88 - 94 |
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| Hlavní autori: | , , , , , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
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Netherlands
Elsevier B.V
01.10.2022
Elsevier |
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| ISSN: | 2405-6316, 2405-6316 |
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| Abstract | •Ablative radiation therapy (A-RT) is effective for locally advanced pancreas cancer.•30 patients received A-RT using diagnostic quality MR-adaptive treatment delivery.•Cumulative incidences of 1-year local and distant progression were 19.3% and 47.4%•Overall and progression-free survival 1-year from A-RT was 80.0% and 39.7%•50 Gray in 5 fractions led to promising 1-year local control and survival.•Most local failures were marginal at the tumor-organ-at-risk (OAR) interface.•No grade 3 or higher toxicities were observed despite adjacent sensitive OARs.
Ablative radiation therapy (A-RT) appears to improve outcomes in locally advanced pancreatic cancer (LAPC) yet requires solutions for respiratory and digestive motion. We report outcomes of A-RT for pancreatic cancer using 1.5 T MR-adaptive treatment delivery.
Between March 2020 and July 2021, we treated 30 patients with pancreatic cancer with 50 Gy in 5 fractions (biologically effective dose [BED10] = 100 Gy10) using a novel compression belt workflow and remote planning on the Unity 1.5 T MR linac system. Cumulative incidence of progression was computed from A-RT initiation with death as a competing risk. Overall (OS) and progression-free survival (PFS) were calculated using Kaplan Meier methods.
Of 30 patients, most (73 %) were locally advanced, 4 (13 %) were metastatic, 2 (7 %) were medically inoperable, and 2 (7 %) were locally recurrent. Most (73 %) received FOLFIRINOX prior to A-RT. Median follow-up times from diagnosis and A-RT were 17.6 (IQR 15.8–23.1) and 11.5 months (IQR 9.7–16.1), respectively. Cumulative incidences at 1-year of local and distant progression were 19.3 % (95 %CI 6.7–36.8 %) and 47.4 % (95 %CI 26.7–65.6 %), respectively. Median OS from diagnosis and A-RT were not reached. One-year OS from diagnosis and A-RT were 96.4 % (95 %CI 77.2–99.5 %) and 80.0 % (95 %CI 57.3–91.4 %), respectively. Median and 1-year PFS were 10.1 months (95 %CI 4.4–14.4) and 39.7 % (95 %CI 20.3–58.5 %), respectively. No grade 3 + toxicities were observed.
A-RT using the 1.5 T Unity MR Linac resulted in promising LC and OS with no severe toxicity in patients with LAPC despite radiosensitive organs adjacent to the target volumes. Longer follow-up is needed to assess long-term outcomes. |
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| AbstractList | •
Ablative radiation therapy (A-RT) is effective for locally advanced pancreas cancer.
•
30 patients received A-RT using diagnostic quality MR-adaptive treatment delivery.
•
Cumulative incidences of 1-year local and distant progression were 19.3% and 47.4%
•
Overall and progression-free survival 1-year from A-RT was 80.0% and 39.7%
•
50 Gray in 5 fractions led to promising 1-year local control and survival.
•
Most local failures were marginal at the tumor-organ-at-risk (OAR) interface.
•
No grade 3 or higher toxicities were observed despite adjacent sensitive OARs. •Ablative radiation therapy (A-RT) is effective for locally advanced pancreas cancer.•30 patients received A-RT using diagnostic quality MR-adaptive treatment delivery.•Cumulative incidences of 1-year local and distant progression were 19.3% and 47.4%•Overall and progression-free survival 1-year from A-RT was 80.0% and 39.7%•50 Gray in 5 fractions led to promising 1-year local control and survival.•Most local failures were marginal at the tumor-organ-at-risk (OAR) interface.•No grade 3 or higher toxicities were observed despite adjacent sensitive OARs. Ablative radiation therapy (A-RT) appears to improve outcomes in locally advanced pancreatic cancer (LAPC) yet requires solutions for respiratory and digestive motion. We report outcomes of A-RT for pancreatic cancer using 1.5 T MR-adaptive treatment delivery. Between March 2020 and July 2021, we treated 30 patients with pancreatic cancer with 50 Gy in 5 fractions (biologically effective dose [BED10] = 100 Gy10) using a novel compression belt workflow and remote planning on the Unity 1.5 T MR linac system. Cumulative incidence of progression was computed from A-RT initiation with death as a competing risk. Overall (OS) and progression-free survival (PFS) were calculated using Kaplan Meier methods. Of 30 patients, most (73 %) were locally advanced, 4 (13 %) were metastatic, 2 (7 %) were medically inoperable, and 2 (7 %) were locally recurrent. Most (73 %) received FOLFIRINOX prior to A-RT. Median follow-up times from diagnosis and A-RT were 17.6 (IQR 15.8–23.1) and 11.5 months (IQR 9.7–16.1), respectively. Cumulative incidences at 1-year of local and distant progression were 19.3 % (95 %CI 6.7–36.8 %) and 47.4 % (95 %CI 26.7–65.6 %), respectively. Median OS from diagnosis and A-RT were not reached. One-year OS from diagnosis and A-RT were 96.4 % (95 %CI 77.2–99.5 %) and 80.0 % (95 %CI 57.3–91.4 %), respectively. Median and 1-year PFS were 10.1 months (95 %CI 4.4–14.4) and 39.7 % (95 %CI 20.3–58.5 %), respectively. No grade 3 + toxicities were observed. A-RT using the 1.5 T Unity MR Linac resulted in promising LC and OS with no severe toxicity in patients with LAPC despite radiosensitive organs adjacent to the target volumes. Longer follow-up is needed to assess long-term outcomes. Purpose: Ablative radiation therapy (A-RT) appears to improve outcomes in locally advanced pancreatic cancer (LAPC) yet requires solutions for respiratory and digestive motion. We report outcomes of A-RT for pancreatic cancer using 1.5 T MR-adaptive treatment delivery. Methods: Between March 2020 and July 2021, we treated 30 patients with pancreatic cancer with 50 Gy in 5 fractions (biologically effective dose [BED10] = 100 Gy10) using a novel compression belt workflow and remote planning on the Unity 1.5 T MR linac system. Cumulative incidence of progression was computed from A-RT initiation with death as a competing risk. Overall (OS) and progression-free survival (PFS) were calculated using Kaplan Meier methods. Results: Of 30 patients, most (73 %) were locally advanced, 4 (13 %) were metastatic, 2 (7 %) were medically inoperable, and 2 (7 %) were locally recurrent. Most (73 %) received FOLFIRINOX prior to A-RT. Median follow-up times from diagnosis and A-RT were 17.6 (IQR 15.8–23.1) and 11.5 months (IQR 9.7–16.1), respectively. Cumulative incidences at 1-year of local and distant progression were 19.3 % (95 %CI 6.7–36.8 %) and 47.4 % (95 %CI 26.7–65.6 %), respectively. Median OS from diagnosis and A-RT were not reached. One-year OS from diagnosis and A-RT were 96.4 % (95 %CI 77.2–99.5 %) and 80.0 % (95 %CI 57.3–91.4 %), respectively. Median and 1-year PFS were 10.1 months (95 %CI 4.4–14.4) and 39.7 % (95 %CI 20.3–58.5 %), respectively. No grade 3 + toxicities were observed. Conclusions: A-RT using the 1.5 T Unity MR Linac resulted in promising LC and OS with no severe toxicity in patients with LAPC despite radiosensitive organs adjacent to the target volumes. Longer follow-up is needed to assess long-term outcomes. Ablative radiation therapy (A-RT) appears to improve outcomes in locally advanced pancreatic cancer (LAPC) yet requires solutions for respiratory and digestive motion. We report outcomes of A-RT for pancreatic cancer using 1.5 T MR-adaptive treatment delivery.PurposeAblative radiation therapy (A-RT) appears to improve outcomes in locally advanced pancreatic cancer (LAPC) yet requires solutions for respiratory and digestive motion. We report outcomes of A-RT for pancreatic cancer using 1.5 T MR-adaptive treatment delivery.Between March 2020 and July 2021, we treated 30 patients with pancreatic cancer with 50 Gy in 5 fractions (biologically effective dose [BED10] = 100 Gy10) using a novel compression belt workflow and remote planning on the Unity 1.5 T MR linac system. Cumulative incidence of progression was computed from A-RT initiation with death as a competing risk. Overall (OS) and progression-free survival (PFS) were calculated using Kaplan Meier methods.MethodsBetween March 2020 and July 2021, we treated 30 patients with pancreatic cancer with 50 Gy in 5 fractions (biologically effective dose [BED10] = 100 Gy10) using a novel compression belt workflow and remote planning on the Unity 1.5 T MR linac system. Cumulative incidence of progression was computed from A-RT initiation with death as a competing risk. Overall (OS) and progression-free survival (PFS) were calculated using Kaplan Meier methods.Of 30 patients, most (73 %) were locally advanced, 4 (13 %) were metastatic, 2 (7 %) were medically inoperable, and 2 (7 %) were locally recurrent. Most (73 %) received FOLFIRINOX prior to A-RT. Median follow-up times from diagnosis and A-RT were 17.6 (IQR 15.8-23.1) and 11.5 months (IQR 9.7-16.1), respectively. Cumulative incidences at 1-year of local and distant progression were 19.3 % (95 %CI 6.7-36.8 %) and 47.4 % (95 %CI 26.7-65.6 %), respectively. Median OS from diagnosis and A-RT were not reached. One-year OS from diagnosis and A-RT were 96.4 % (95 %CI 77.2-99.5 %) and 80.0 % (95 %CI 57.3-91.4 %), respectively. Median and 1-year PFS were 10.1 months (95 %CI 4.4-14.4) and 39.7 % (95 %CI 20.3-58.5 %), respectively. No grade 3 + toxicities were observed.ResultsOf 30 patients, most (73 %) were locally advanced, 4 (13 %) were metastatic, 2 (7 %) were medically inoperable, and 2 (7 %) were locally recurrent. Most (73 %) received FOLFIRINOX prior to A-RT. Median follow-up times from diagnosis and A-RT were 17.6 (IQR 15.8-23.1) and 11.5 months (IQR 9.7-16.1), respectively. Cumulative incidences at 1-year of local and distant progression were 19.3 % (95 %CI 6.7-36.8 %) and 47.4 % (95 %CI 26.7-65.6 %), respectively. Median OS from diagnosis and A-RT were not reached. One-year OS from diagnosis and A-RT were 96.4 % (95 %CI 77.2-99.5 %) and 80.0 % (95 %CI 57.3-91.4 %), respectively. Median and 1-year PFS were 10.1 months (95 %CI 4.4-14.4) and 39.7 % (95 %CI 20.3-58.5 %), respectively. No grade 3 + toxicities were observed.A-RT using the 1.5 T Unity MR Linac resulted in promising LC and OS with no severe toxicity in patients with LAPC despite radiosensitive organs adjacent to the target volumes. Longer follow-up is needed to assess long-term outcomes.ConclusionsA-RT using the 1.5 T Unity MR Linac resulted in promising LC and OS with no severe toxicity in patients with LAPC despite radiosensitive organs adjacent to the target volumes. Longer follow-up is needed to assess long-term outcomes. Ablative radiation therapy (A-RT) appears to improve outcomes in locally advanced pancreatic cancer (LAPC) yet requires solutions for respiratory and digestive motion. We report outcomes of A-RT for pancreatic cancer using 1.5 T MR-adaptive treatment delivery. Between March 2020 and July 2021, we treated 30 patients with pancreatic cancer with 50 Gy in 5 fractions (biologically effective dose [BED10] = 100 Gy10) using a novel compression belt workflow and remote planning on the Unity 1.5 T MR linac system. Cumulative incidence of progression was computed from A-RT initiation with death as a competing risk. Overall (OS) and progression-free survival (PFS) were calculated using Kaplan Meier methods. Of 30 patients, most (73 %) were locally advanced, 4 (13 %) were metastatic, 2 (7 %) were medically inoperable, and 2 (7 %) were locally recurrent. Most (73 %) received FOLFIRINOX prior to A-RT. Median follow-up times from diagnosis and A-RT were 17.6 (IQR 15.8-23.1) and 11.5 months (IQR 9.7-16.1), respectively. Cumulative incidences at 1-year of local and distant progression were 19.3 % (95 %CI 6.7-36.8 %) and 47.4 % (95 %CI 26.7-65.6 %), respectively. Median OS from diagnosis and A-RT were not reached. One-year OS from diagnosis and A-RT were 96.4 % (95 %CI 77.2-99.5 %) and 80.0 % (95 %CI 57.3-91.4 %), respectively. Median and 1-year PFS were 10.1 months (95 %CI 4.4-14.4) and 39.7 % (95 %CI 20.3-58.5 %), respectively. No grade 3 + toxicities were observed. A-RT using the 1.5 T Unity MR Linac resulted in promising LC and OS with no severe toxicity in patients with LAPC despite radiosensitive organs adjacent to the target volumes. Longer follow-up is needed to assess long-term outcomes. |
| Author | Tringale, Kathryn R. Tyagi, Neelam Wu, Abraham Marsha Reyngold Varghese, Anna M. Yu, Kenneth Khalil, Danny N. O'Reilly, Eileen M. Park, Wungki Romesser, Paul B. Godoy Scripes, Paola Crane, Christopher H. |
| Author_xml | – sequence: 1 givenname: Kathryn R. surname: Tringale fullname: Tringale, Kathryn R. email: tringalk@mskcc.org organization: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, United States – sequence: 2 givenname: Neelam surname: Tyagi fullname: Tyagi, Neelam organization: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, United States – sequence: 3 surname: Marsha Reyngold fullname: Marsha Reyngold organization: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, United States – sequence: 4 givenname: Paul B. surname: Romesser fullname: Romesser, Paul B. organization: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, United States – sequence: 5 givenname: Abraham surname: Wu fullname: Wu, Abraham organization: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, United States – sequence: 6 givenname: Eileen M. surname: O'Reilly fullname: O'Reilly, Eileen M. organization: Department of Medicine, Memorial Sloan Kettering Cancer Center, United States – sequence: 7 givenname: Anna M. surname: Varghese fullname: Varghese, Anna M. organization: Department of Medicine, Memorial Sloan Kettering Cancer Center, United States – sequence: 8 givenname: Paola surname: Godoy Scripes fullname: Godoy Scripes, Paola organization: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, United States – sequence: 9 givenname: Danny N. surname: Khalil fullname: Khalil, Danny N. organization: Department of Medicine, Memorial Sloan Kettering Cancer Center, United States – sequence: 10 givenname: Wungki surname: Park fullname: Park, Wungki organization: Department of Medicine, Memorial Sloan Kettering Cancer Center, United States – sequence: 11 givenname: Kenneth surname: Yu fullname: Yu, Kenneth organization: Department of Medicine, Memorial Sloan Kettering Cancer Center, United States – sequence: 12 givenname: Christopher H. surname: Crane fullname: Crane, Christopher H. email: cranec1@mskcc.org organization: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, United States |
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| Cites_doi | 10.1016/j.ijrobp.2015.12.003 10.1016/j.prro.2020.09.005 10.1016/j.ijrobp.2021.02.008 10.1016/j.radonc.2017.07.028 10.1016/0360-3016(95)00060-C 10.1186/s13014-019-1309-x 10.1016/S1470-2045(16)00172-8 10.1016/j.radonc.2017.11.032 10.1016/j.radonc.2020.11.006 10.1016/j.tipsro.2020.06.001 10.1016/j.radonc.2004.12.022 10.1001/jamaoncol.2021.0057 10.1200/JCO.2010.33.8038 10.1200/JCO.2011.34.8904 10.1002/cam4.2100 10.1186/s13014-019-1275-3 10.1001/jamanetworkopen.2021.4708 10.1056/NEJMoa1809775 10.1016/j.radonc.2018.11.019 10.1200/JCO.2008.17.7188 10.1016/j.ijrobp.2008.01.051 10.1038/s41571-018-0112-1 10.1245/s10434-014-4225-1 10.1093/annonc/mdn281 10.1001/jama.2016.4324 10.1002/cncr.29161 |
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| References | Cox, Tetz, Pajak (b0135) 1995; 31 Krishnan, Chadha, Suh, Al (b0140) 2016; 94 Rudra, Jiang, Rosenberg, Olsen, Roach, Wan (b0115) 2019; 8 Chuong, Bryant, Mittauer, Hall, Kotecha, Alvarez (b0120) 2021; 11 Hoyer, Roed, Sengelov, Traberg, Al (b0055) 2005; 76 Henke, Kashani, Robinson, Curcuru, DeWees, Bradley (b0100) 2018; 126 Iacobuzio-Donahue, Fu, Yachida, Al (b0040) 2009; 27 Reyngold, Parikh, Crane (b0080) 2019; 14 Tyagi, Liang, Burleson, Subashi, Scripes, Tringale (b0130) 2021; 19 Reyngold, O’Reilly, Varghese, Fiascorano, Al (b0075) 2021; 7 Conroy, Hammel, Hebbar, Abeldghani, Wei, Al (b0020) 2018; 379 Boldrini, Cusumano, Cellini, Azario, Mattiucci, Al (b0090) 2019; 14 Bohoudi, Bruynzeel, Senan, Cuijpers, SLotmanm, Lagerwaard (b0105) 2017; 125 Hassanzadeh, Rudra, Bommireddy, Hawkins, Wang-Gillam, Fields (b0125) 2021; 6 Courtney, Paravati, Atwood, Raja, Zimmerman (b0145) 2021; 110 Schellenberg, Goodman, Lee, Chang, Al (b0065) 2008; 72 Bruynzeel, Lagerwaard (b0095) 2019; 18 Suker, Beumer, Sadot, Marthy, Faris, Mellon (b0015) 2016; 17 Teriaca, Loi, Suker, Eskens, van Eijck, Nuyttens (b0150) 2021; 155 Strobel, Neoptolemos, Jager, Buchler (b0025) 2019; 16 Hammel, Huguet, Laethem, Goldstein, Al (b0070) 2016; 315 Loehrer, Feng, Cardenes, Wagner, Brell, Al (b0050) 2011; 29 Siegel, Miller, Fuchs, Jemal (b0005) 2021; 71 Herman, Chang, Goodman, Dholakia, Roman, Al (b0060) 2015; 121 Bohoudi, Bruynzeel, Meijerink, Senan, Slotman, Palacios (b0110) 2019; 132 Chauffert, Mornex, Bonnetain, Rougier, Mariette, Bouche (b0045) 2008; 19 Placidi, Romano, Chiloiro, Cusumano, Boldrini, Cellini (b0085) 2020; 15 Rahib, Wehner, Matrisian, Nead (b0010) 2021; 4 Blazer, Wu, Goldberg, Phillips, Al (b0030) 2015; 22 Crane, Varadhachary, Yordy, Staerkel, Javle, Al (b0035) 2011; 29 Paulson, Ahunbay, Chen, Mickevicius, Chen, Al (b0155) 2020; 23 Reyngold (10.1016/j.phro.2022.10.003_b0080) 2019; 14 Bohoudi (10.1016/j.phro.2022.10.003_b0105) 2017; 125 Blazer (10.1016/j.phro.2022.10.003_b0030) 2015; 22 Hassanzadeh (10.1016/j.phro.2022.10.003_b0125) 2021; 6 Henke (10.1016/j.phro.2022.10.003_b0100) 2018; 126 Loehrer (10.1016/j.phro.2022.10.003_b0050) 2011; 29 Conroy (10.1016/j.phro.2022.10.003_b0020) 2018; 379 Paulson (10.1016/j.phro.2022.10.003_b0155) 2020; 23 Tyagi (10.1016/j.phro.2022.10.003_b0130) 2021; 19 Iacobuzio-Donahue (10.1016/j.phro.2022.10.003_b0040) 2009; 27 Herman (10.1016/j.phro.2022.10.003_b0060) 2015; 121 Rudra (10.1016/j.phro.2022.10.003_b0115) 2019; 8 Crane (10.1016/j.phro.2022.10.003_b0035) 2011; 29 Teriaca (10.1016/j.phro.2022.10.003_b0150) 2021; 155 Courtney (10.1016/j.phro.2022.10.003_b0145) 2021; 110 Schellenberg (10.1016/j.phro.2022.10.003_b0065) 2008; 72 Chauffert (10.1016/j.phro.2022.10.003_b0045) 2008; 19 Hoyer (10.1016/j.phro.2022.10.003_b0055) 2005; 76 Rahib (10.1016/j.phro.2022.10.003_b0010) 2021; 4 Boldrini (10.1016/j.phro.2022.10.003_b0090) 2019; 14 Krishnan (10.1016/j.phro.2022.10.003_b0140) 2016; 94 Hammel (10.1016/j.phro.2022.10.003_b0070) 2016; 315 Siegel (10.1016/j.phro.2022.10.003_b0005) 2021; 71 Strobel (10.1016/j.phro.2022.10.003_b0025) 2019; 16 Reyngold (10.1016/j.phro.2022.10.003_b0075) 2021; 7 Bohoudi (10.1016/j.phro.2022.10.003_b0110) 2019; 132 Bruynzeel (10.1016/j.phro.2022.10.003_b0095) 2019; 18 Placidi (10.1016/j.phro.2022.10.003_b0085) 2020; 15 Cox (10.1016/j.phro.2022.10.003_b0135) 1995; 31 Suker (10.1016/j.phro.2022.10.003_b0015) 2016; 17 Chuong (10.1016/j.phro.2022.10.003_b0120) 2021; 11 |
| References_xml | – volume: 23 start-page: 72 year: 2020 end-page: 79 ident: b0155 article-title: 4D-MRI driven MR-guided online adaptive radiotherapy for abdominal stereotactic body radiation therapy on a high field MR-Linac: Implementation and initial clinical experience publication-title: Clin Transl Radiat Oncol – volume: 315 start-page: 1844 year: 2016 end-page: 1853 ident: b0070 article-title: Effect of Chemoradiotherapy vs Chemotherapy on Survival in Patients With Locally Advanced Pancreatic Cancer Controlled After 4 Months of Gemcitabine With or Without Erlotinib: The LAP07 Randomized Clinical Trial publication-title: JAMA – volume: 15 start-page: 15 year: 2020 end-page: 21 ident: b0085 article-title: On-line adaptive MR guided radiotherapy for locally advanced pancreatic cancer: Clinical and dosimetric considerations publication-title: Tech Innov Patient Support Radiat Oncol – volume: 17 start-page: 801 year: 2016 end-page: 810 ident: b0015 article-title: FOLFIRINOX for locally advanced pancreatic cancer: a systematic review and patient-level meta-analysis publication-title: Lancet Oncol – volume: 14 start-page: 95 year: 2019 ident: b0080 article-title: Ablative radiation therapy for locally advanced pancreatic cancer: techniques and results publication-title: Radiat Oncol – volume: 125 start-page: 439 year: 2017 end-page: 444 ident: b0105 article-title: Fast and robust online adaptive planning in stereotactic MR-guided adaptive radiation therapy (SMART) for pancreatic cancer publication-title: Radiother Oncol – volume: 29 start-page: 3037 year: 2011 end-page: 3043 ident: b0035 article-title: Phase II trial of cetuximab, gemcitabine, and oxaliplatin followed by chemoradiation with cetuximab for locally advanced (T4) pancreatic adenocarcinoma: correlation of Smad4(Dpc4) immunostaining with pattern of disease progression publication-title: J Clin Oncol – volume: 8 start-page: 2123 year: 2019 end-page: 2132 ident: b0115 article-title: Using adaptive magnetic resonance image-guided radiation therapy for treatment of inoperable pancreatic cancer publication-title: Cancer Med – volume: 19 start-page: 53 year: 2021 end-page: 59 ident: b0130 article-title: Feasibility of ablative stereotactic body radiation therapy of pancreas cancer patients on a 1.5 Tesla magnetic resonance-linac system using abdominal compression. Phys Imaging publication-title: Radiat Oncol – volume: 71 start-page: 7 year: 2021 end-page: 33 ident: b0005 article-title: Cancer statistics, 2021 publication-title: CA Cancer J Clin – volume: 22 start-page: 1153 year: 2015 end-page: 1159 ident: b0030 article-title: Neoadjuvant modified (m) FOLFIRINOX for locally advanced unresectable (LAPC) and borderline resectable (BRPC) adenocarcinoma of the pancreas publication-title: Ann Surg Oncol – volume: 6 year: 2021 ident: b0125 article-title: Ablative five-fraction stereotactic body radiation thearpy for inoperable pancreatic cancer using online MR-guided adaptation publication-title: Adv Radiat Oncol – volume: 110 start-page: 1003 year: 2021 end-page: 1012 ident: b0145 article-title: Phase I Trial of Stereotactic Body Radiation Therapy Dose Escalation in Pancreatic Cancer publication-title: Int J Radiat Oncol – volume: 29 start-page: 4105 year: 2011 end-page: 4112 ident: b0050 article-title: Gemcitabine alone versus gemcitabine plus radiotherapy in patients with locally advanced pancreatic cancer: an Eastern Cooperative Oncology Group trial publication-title: J Clin Oncol – volume: 379 start-page: 2395 year: 2018 end-page: 2406 ident: b0020 article-title: FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer publication-title: N Engl J Med – volume: 121 start-page: 1128 year: 2015 end-page: 1137 ident: b0060 article-title: Phase 2 multi-institutional trial evaluating gemcitabine and stereotactic body radiotherapy for patients with locally advanced unresectable pancreatic adenocarcinoma publication-title: Cancer – volume: 7 start-page: 735 year: 2021 end-page: 738 ident: b0075 article-title: Association of Ablative Radiation Therapy With Survival Among Patients With Inoperable Pancreatic Cancer publication-title: JAMA Oncol – volume: 72 start-page: 678 year: 2008 end-page: 686 ident: b0065 article-title: Gemcitabine chemotherapy and single-fraction stereotactic body radiotherapy for locally advanced pancreatic cancer publication-title: Int J Radiat Oncol Biol Phys – volume: 14 year: 2019 ident: b0090 article-title: Online adaptive magnetic resonance guided radiotherapy for pancreatic cancer: state of the art, pearls, and pitfalls publication-title: Radiat Oncol – volume: 27 start-page: 1806 year: 2009 end-page: 1813 ident: b0040 article-title: DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer publication-title: J Clin Oncol – volume: 94 start-page: 755 year: 2016 end-page: 765 ident: b0140 article-title: Focal radiation therapy dose escalation improves overall survival in locally advanced pancreatic cancer patients receiving induction chemotherapy and consolidative chemoradiation publication-title: Int J Radiat Oncol Biol Phys – volume: 31 start-page: 1341 year: 1995 end-page: 1346 ident: b0135 article-title: Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC) publication-title: Int J Radiat Oncol – volume: 4 start-page: e214708 year: 2021 ident: b0010 article-title: Estimated Projection of US Cancer Incidence and Death to 2040 publication-title: JAMA Netw Open – volume: 132 start-page: 16 year: 2019 end-page: 22 ident: b0110 article-title: Identification of patients with locally advanced pancreatic cancer benefitting from plan adaptation in MR-guided radiation therapy publication-title: Radiother Oncol – volume: 19 start-page: 1592 year: 2008 end-page: 1599 ident: b0045 article-title: Phase III trial comparing intensive induction chemoradiotherapy (60 Gy, infusional 5-FU and intermittent cisplatin) followed by maintenance gemcitabine with gemcitabine alone for locally advanced unresectable pancreatic cancer. Definitive results of the 2 publication-title: Ann Oncol – volume: 76 start-page: 48 year: 2005 end-page: 53 ident: b0055 article-title: Phase-II study on stereotactic radiotherapy of locally advanced pancreatic carcinoma publication-title: Radiother Oncol – volume: 18 start-page: 128 year: 2019 end-page: 130 ident: b0095 article-title: The role of biological dose-escalation for pancreatic cance publication-title: Clin Transl Radiat Oncol – volume: 126 start-page: 519 year: 2018 end-page: 526 ident: b0100 article-title: Phase I trial of stereotactic MR-guided online adaptive radiation therapy (SMART) for the treatment of oligometastatic or unresectable primary malignancies of the abdomen publication-title: Radiother Oncol – volume: 11 start-page: 134 year: 2021 end-page: 147 ident: b0120 article-title: Ablative 5-fraction stereotactic magnetic resonance-guided radiation therapy with on-table adaptive replanning and elective nodal irradiation for inoperable pancreas cancer publication-title: Pract Radiat Oncol – volume: 155 start-page: 232 year: 2021 end-page: 236 ident: b0150 article-title: A phase II study of stereotactic radiotherapy after FOLFIRINOX for locally advanced pancreatic cancer (LAPC-1 trial): Long-term outcome publication-title: Radiother Oncol – volume: 16 start-page: 11 year: 2019 end-page: 26 ident: b0025 article-title: Optimizing the outcomes of pancreatic cancer surgery publication-title: Nat Rev Clin Oncol – volume: 94 start-page: 755 year: 2016 ident: 10.1016/j.phro.2022.10.003_b0140 article-title: Focal radiation therapy dose escalation improves overall survival in locally advanced pancreatic cancer patients receiving induction chemotherapy and consolidative chemoradiation publication-title: Int J Radiat Oncol Biol Phys doi: 10.1016/j.ijrobp.2015.12.003 – volume: 11 start-page: 134 year: 2021 ident: 10.1016/j.phro.2022.10.003_b0120 article-title: Ablative 5-fraction stereotactic magnetic resonance-guided radiation therapy with on-table adaptive replanning and elective nodal irradiation for inoperable pancreas cancer publication-title: Pract Radiat Oncol doi: 10.1016/j.prro.2020.09.005 – volume: 110 start-page: 1003 year: 2021 ident: 10.1016/j.phro.2022.10.003_b0145 article-title: Phase I Trial of Stereotactic Body Radiation Therapy Dose Escalation in Pancreatic Cancer publication-title: Int J Radiat Oncol doi: 10.1016/j.ijrobp.2021.02.008 – volume: 125 start-page: 439 year: 2017 ident: 10.1016/j.phro.2022.10.003_b0105 article-title: Fast and robust online adaptive planning in stereotactic MR-guided adaptive radiation therapy (SMART) for pancreatic cancer publication-title: Radiother Oncol doi: 10.1016/j.radonc.2017.07.028 – volume: 31 start-page: 1341 year: 1995 ident: 10.1016/j.phro.2022.10.003_b0135 article-title: Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC) publication-title: Int J Radiat Oncol doi: 10.1016/0360-3016(95)00060-C – volume: 14 start-page: 95 year: 2019 ident: 10.1016/j.phro.2022.10.003_b0080 article-title: Ablative radiation therapy for locally advanced pancreatic cancer: techniques and results publication-title: Radiat Oncol doi: 10.1186/s13014-019-1309-x – volume: 17 start-page: 801 year: 2016 ident: 10.1016/j.phro.2022.10.003_b0015 article-title: FOLFIRINOX for locally advanced pancreatic cancer: a systematic review and patient-level meta-analysis publication-title: Lancet Oncol doi: 10.1016/S1470-2045(16)00172-8 – volume: 126 start-page: 519 year: 2018 ident: 10.1016/j.phro.2022.10.003_b0100 article-title: Phase I trial of stereotactic MR-guided online adaptive radiation therapy (SMART) for the treatment of oligometastatic or unresectable primary malignancies of the abdomen publication-title: Radiother Oncol doi: 10.1016/j.radonc.2017.11.032 – volume: 71 start-page: 7 year: 2021 ident: 10.1016/j.phro.2022.10.003_b0005 article-title: Cancer statistics, 2021 publication-title: CA Cancer J Clin – volume: 155 start-page: 232 year: 2021 ident: 10.1016/j.phro.2022.10.003_b0150 article-title: A phase II study of stereotactic radiotherapy after FOLFIRINOX for locally advanced pancreatic cancer (LAPC-1 trial): Long-term outcome publication-title: Radiother Oncol doi: 10.1016/j.radonc.2020.11.006 – volume: 6 year: 2021 ident: 10.1016/j.phro.2022.10.003_b0125 article-title: Ablative five-fraction stereotactic body radiation thearpy for inoperable pancreatic cancer using online MR-guided adaptation publication-title: Adv Radiat Oncol – volume: 19 start-page: 53 year: 2021 ident: 10.1016/j.phro.2022.10.003_b0130 article-title: Feasibility of ablative stereotactic body radiation therapy of pancreas cancer patients on a 1.5 Tesla magnetic resonance-linac system using abdominal compression. Phys Imaging publication-title: Radiat Oncol – volume: 15 start-page: 15 year: 2020 ident: 10.1016/j.phro.2022.10.003_b0085 article-title: On-line adaptive MR guided radiotherapy for locally advanced pancreatic cancer: Clinical and dosimetric considerations publication-title: Tech Innov Patient Support Radiat Oncol doi: 10.1016/j.tipsro.2020.06.001 – volume: 76 start-page: 48 year: 2005 ident: 10.1016/j.phro.2022.10.003_b0055 article-title: Phase-II study on stereotactic radiotherapy of locally advanced pancreatic carcinoma publication-title: Radiother Oncol doi: 10.1016/j.radonc.2004.12.022 – volume: 7 start-page: 735 year: 2021 ident: 10.1016/j.phro.2022.10.003_b0075 article-title: Association of Ablative Radiation Therapy With Survival Among Patients With Inoperable Pancreatic Cancer publication-title: JAMA Oncol doi: 10.1001/jamaoncol.2021.0057 – volume: 29 start-page: 3037 year: 2011 ident: 10.1016/j.phro.2022.10.003_b0035 article-title: Phase II trial of cetuximab, gemcitabine, and oxaliplatin followed by chemoradiation with cetuximab for locally advanced (T4) pancreatic adenocarcinoma: correlation of Smad4(Dpc4) immunostaining with pattern of disease progression publication-title: J Clin Oncol doi: 10.1200/JCO.2010.33.8038 – volume: 23 start-page: 72 year: 2020 ident: 10.1016/j.phro.2022.10.003_b0155 article-title: 4D-MRI driven MR-guided online adaptive radiotherapy for abdominal stereotactic body radiation therapy on a high field MR-Linac: Implementation and initial clinical experience publication-title: Clin Transl Radiat Oncol – volume: 29 start-page: 4105 year: 2011 ident: 10.1016/j.phro.2022.10.003_b0050 article-title: Gemcitabine alone versus gemcitabine plus radiotherapy in patients with locally advanced pancreatic cancer: an Eastern Cooperative Oncology Group trial publication-title: J Clin Oncol doi: 10.1200/JCO.2011.34.8904 – volume: 8 start-page: 2123 year: 2019 ident: 10.1016/j.phro.2022.10.003_b0115 article-title: Using adaptive magnetic resonance image-guided radiation therapy for treatment of inoperable pancreatic cancer publication-title: Cancer Med doi: 10.1002/cam4.2100 – volume: 14 year: 2019 ident: 10.1016/j.phro.2022.10.003_b0090 article-title: Online adaptive magnetic resonance guided radiotherapy for pancreatic cancer: state of the art, pearls, and pitfalls publication-title: Radiat Oncol doi: 10.1186/s13014-019-1275-3 – volume: 4 start-page: e214708 year: 2021 ident: 10.1016/j.phro.2022.10.003_b0010 article-title: Estimated Projection of US Cancer Incidence and Death to 2040 publication-title: JAMA Netw Open doi: 10.1001/jamanetworkopen.2021.4708 – volume: 379 start-page: 2395 year: 2018 ident: 10.1016/j.phro.2022.10.003_b0020 article-title: FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer publication-title: N Engl J Med doi: 10.1056/NEJMoa1809775 – volume: 132 start-page: 16 year: 2019 ident: 10.1016/j.phro.2022.10.003_b0110 article-title: Identification of patients with locally advanced pancreatic cancer benefitting from plan adaptation in MR-guided radiation therapy publication-title: Radiother Oncol doi: 10.1016/j.radonc.2018.11.019 – volume: 27 start-page: 1806 year: 2009 ident: 10.1016/j.phro.2022.10.003_b0040 article-title: DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer publication-title: J Clin Oncol doi: 10.1200/JCO.2008.17.7188 – volume: 72 start-page: 678 year: 2008 ident: 10.1016/j.phro.2022.10.003_b0065 article-title: Gemcitabine chemotherapy and single-fraction stereotactic body radiotherapy for locally advanced pancreatic cancer publication-title: Int J Radiat Oncol Biol Phys doi: 10.1016/j.ijrobp.2008.01.051 – volume: 18 start-page: 128 year: 2019 ident: 10.1016/j.phro.2022.10.003_b0095 article-title: The role of biological dose-escalation for pancreatic cance publication-title: Clin Transl Radiat Oncol – volume: 16 start-page: 11 year: 2019 ident: 10.1016/j.phro.2022.10.003_b0025 article-title: Optimizing the outcomes of pancreatic cancer surgery publication-title: Nat Rev Clin Oncol doi: 10.1038/s41571-018-0112-1 – volume: 22 start-page: 1153 year: 2015 ident: 10.1016/j.phro.2022.10.003_b0030 article-title: Neoadjuvant modified (m) FOLFIRINOX for locally advanced unresectable (LAPC) and borderline resectable (BRPC) adenocarcinoma of the pancreas publication-title: Ann Surg Oncol doi: 10.1245/s10434-014-4225-1 – volume: 19 start-page: 1592 year: 2008 ident: 10.1016/j.phro.2022.10.003_b0045 article-title: Phase III trial comparing intensive induction chemoradiotherapy (60 Gy, infusional 5-FU and intermittent cisplatin) followed by maintenance gemcitabine with gemcitabine alone for locally advanced unresectable pancreatic cancer. Definitive results of the 2 publication-title: Ann Oncol doi: 10.1093/annonc/mdn281 – volume: 315 start-page: 1844 year: 2016 ident: 10.1016/j.phro.2022.10.003_b0070 article-title: Effect of Chemoradiotherapy vs Chemotherapy on Survival in Patients With Locally Advanced Pancreatic Cancer Controlled After 4 Months of Gemcitabine With or Without Erlotinib: The LAP07 Randomized Clinical Trial publication-title: JAMA doi: 10.1001/jama.2016.4324 – volume: 121 start-page: 1128 year: 2015 ident: 10.1016/j.phro.2022.10.003_b0060 article-title: Phase 2 multi-institutional trial evaluating gemcitabine and stereotactic body radiotherapy for patients with locally advanced unresectable pancreatic adenocarcinoma publication-title: Cancer doi: 10.1002/cncr.29161 |
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| Snippet | •Ablative radiation therapy (A-RT) is effective for locally advanced pancreas cancer.•30 patients received A-RT using diagnostic quality MR-adaptive treatment... Ablative radiation therapy (A-RT) appears to improve outcomes in locally advanced pancreatic cancer (LAPC) yet requires solutions for respiratory and digestive... • Ablative radiation therapy (A-RT) is effective for locally advanced pancreas cancer. • 30 patients received A-RT using diagnostic quality MR-adaptive... Purpose: Ablative radiation therapy (A-RT) appears to improve outcomes in locally advanced pancreatic cancer (LAPC) yet requires solutions for respiratory and... |
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| Title | Stereotactic ablative radiation for pancreatic cancer on a 1.5 Telsa magnetic resonance-linac system |
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