Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody

Circulating influenza viruses evade neutralization in their human hosts by acquiring escape mutations at epitopes of prevalent antibodies. A goal for next-generation influenza vaccines is to reduce escape likelihood by selectively eliciting antibodies recognizing conserved surfaces on the viral hema...

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Vydané v:	Proceedings of the National Academy of Sciences - PNAS Ročník 115; číslo 1; s. 168
Hlavní autori:	Raymond, Donald D, Bajic, Goran, Ferdman, Jack, Suphaphiphat, Pirada, Settembre, Ethan C, Moody, M Anthony, Schmidt, Aaron G, Harrison, Stephen C
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 02.01.2018
Predmet:	B-cell memory influenza vaccine hemagglutinin affinity maturation
ISSN:	1091-6490, 1091-6490
On-line prístup:	Zistit podrobnosti o prístupe
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