50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study
Comprehensive long-term data on atrial fibrillation trends in men and women are scant. We aimed to provide such data through analysis of the Framingham cohort over 50 years. We investigated trends in incidence, prevalence, and risk factors for atrial fibrillation and its association with stroke and...
Gespeichert in:
| Veröffentlicht in: | The Lancet (British edition) Jg. 386; H. 9989; S. 154 - 162 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
England
Elsevier Ltd
11.07.2015
Elsevier Limited |
| Schlagworte: | |
| ISSN: | 0140-6736, 1474-547X, 1474-547X |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Abstract | Comprehensive long-term data on atrial fibrillation trends in men and women are scant. We aimed to provide such data through analysis of the Framingham cohort over 50 years.
We investigated trends in incidence, prevalence, and risk factors for atrial fibrillation and its association with stroke and mortality after onset in 9511 participants enrolled in the Framingham Heart Study between 1958 and 2007. We analysed trends within 10 year groups (1958–67, 1968–77, 1978–87, 1988–97, and 1998–2007), stratified by sex.
During 50 years of observation (202 417 person-years), 1544 cases of new-onset atrial fibrillation occurred (of whom 723 [47%] were women). Between 1958–67 and 1998–2007, age-adjusted prevalence of atrial fibrillation quadrupled from 20·4 to 96·2 cases per 1000 person-years in men and from 13·7 to 49·4 cases per 1000 person-years in women; age-adjusted incidence increased from 3·7 to 13·4 new cases per 1000 person-years in men and from 2·5 to 8·6 new cases per 1000 person-years in women (ptrend<0·0001 for all comparisons). For atrial fibrillation diagnosed by electrocardiograph (ECG) during routine Framingham examinations, age-adjusted prevalence per 1000 person-years increased (12·6 in 1958–67 to 25·7 in 1998–2007 in men, ptrend=0·0007; 8·1 to 11·8 in women, ptrend=0·009). However, age-adjusted incidence of atrial fibrillation by Framingham Heart Study ECGs did not change significantly with time. Although the prevalence of most risk factors changed over time, their associated hazards for atrial fibrillation changed little. Multivariable-adjusted proportional hazards models revealed a 74% (95% CI 50–86%) decrease in stroke (hazards ratio [HR] 3·77, 95% CI 1·98–7·20 in 1958–1967 compared with 1998–2007; ptrend=0·0001) and a 25% (95% CI −3–46%) decrease in mortality (HR 1·34, 95% CI 0·97–1·86 in 1958–1967 compared with 1998–2007; ptrend=0·003) in 20 years following atrial fibrillation onset.
Trends of increased incidence and prevalence of atrial fibrillation in the community were probably partly due to enhanced surveillance. Measures are needed to enhance early detection of atrial fibrillation, through increased awareness coupled with targeted screening programmes and risk factor-specific prevention.
NIH, NHLBI, NINDS, Deutsche Forschungsgemeinschaft. |
|---|---|
| AbstractList | Comprehensive long-term data on atrial fibrillation trends in men and women are scant. We aimed to provide such data through analysis of the Framingham cohort over 50 years.
We investigated trends in incidence, prevalence, and risk factors for atrial fibrillation and its association with stroke and mortality after onset in 9511 participants enrolled in the Framingham Heart Study between 1958 and 2007. We analysed trends within 10 year groups (1958-67, 1968-77, 1978-87, 1988-97, and 1998-2007), stratified by sex.
During 50 years of observation (202,417 person-years), 1544 cases of new-onset atrial fibrillation occurred (of whom 723 [47%] were women). Between 1958-67 and 1998-2007, age-adjusted prevalence of atrial fibrillation quadrupled from 20·4 to 96·2 cases per 1000 person-years in men and from 13·7 to 49·4 cases per 1000 person-years in women; age-adjusted incidence increased from 3·7 to 13·4 new cases per 1000 person-years in men and from 2·5 to 8·6 new cases per 1000 person-years in women (ptrend<0·0001 for all comparisons). For atrial fibrillation diagnosed by electrocardiograph (ECG) during routine Framingham examinations, age-adjusted prevalence per 1000 person-years increased (12·6 in 1958-67 to 25·7 in 1998-2007 in men, ptrend=0·0007; 8·1 to 11·8 in women, ptrend=0·009). However, age-adjusted incidence of atrial fibrillation by Framingham Heart Study ECGs did not change significantly with time. Although the prevalence of most risk factors changed over time, their associated hazards for atrial fibrillation changed little. Multivariable-adjusted proportional hazards models revealed a 74% (95% CI 50-86%) decrease in stroke (hazards ratio [HR] 3·77, 95% CI 1·98-7·20 in 1958-1967 compared with 1998-2007; ptrend=0·0001) and a 25% (95% CI -3-46%) decrease in mortality (HR 1·34, 95% CI 0·97-1·86 in 1958-1967 compared with 1998-2007; ptrend=0·003) in 20 years following atrial fibrillation onset.
Trends of increased incidence and prevalence of atrial fibrillation in the community were probably partly due to enhanced surveillance. Measures are needed to enhance early detection of atrial fibrillation, through increased awareness coupled with targeted screening programmes and risk factor-specific prevention.
NIH, NHLBI, NINDS, Deutsche Forschungsgemeinschaft. Comprehensive long-term data on atrial fibrillation trends in men and women are scant. We aimed to provide such data through analysis of the Framingham cohort over 50 years. We investigated trends in incidence, prevalence, and risk factors for atrial fibrillation and its association with stroke and mortality after onset in 9511 participants enrolled in the Framingham Heart Study between 1958 and 2007. We analysed trends within 10 year groups (1958–67, 1968–77, 1978–87, 1988–97, and 1998–2007), stratified by sex. During 50 years of observation (202 417 person-years), 1544 cases of new-onset atrial fibrillation occurred (of whom 723 [47%] were women). Between 1958–67 and 1998–2007, age-adjusted prevalence of atrial fibrillation quadrupled from 20·4 to 96·2 cases per 1000 person-years in men and from 13·7 to 49·4 cases per 1000 person-years in women; age-adjusted incidence increased from 3·7 to 13·4 new cases per 1000 person-years in men and from 2·5 to 8·6 new cases per 1000 person-years in women (ptrend<0·0001 for all comparisons). For atrial fibrillation diagnosed by electrocardiograph (ECG) during routine Framingham examinations, age-adjusted prevalence per 1000 person-years increased (12·6 in 1958–67 to 25·7 in 1998–2007 in men, ptrend=0·0007; 8·1 to 11·8 in women, ptrend=0·009). However, age-adjusted incidence of atrial fibrillation by Framingham Heart Study ECGs did not change significantly with time. Although the prevalence of most risk factors changed over time, their associated hazards for atrial fibrillation changed little. Multivariable-adjusted proportional hazards models revealed a 74% (95% CI 50–86%) decrease in stroke (hazards ratio [HR] 3·77, 95% CI 1·98–7·20 in 1958–1967 compared with 1998–2007; ptrend=0·0001) and a 25% (95% CI −3–46%) decrease in mortality (HR 1·34, 95% CI 0·97–1·86 in 1958–1967 compared with 1998–2007; ptrend=0·003) in 20 years following atrial fibrillation onset. Trends of increased incidence and prevalence of atrial fibrillation in the community were probably partly due to enhanced surveillance. Measures are needed to enhance early detection of atrial fibrillation, through increased awareness coupled with targeted screening programmes and risk factor-specific prevention. NIH, NHLBI, NINDS, Deutsche Forschungsgemeinschaft. Comprehensive long-term data on atrial fibrillation trends in men and women are scant. We aimed to provide such data through analysis of the Framingham cohort over 50 years. Methods We investigated trends in incidence, prevalence, and risk factors for atrial fibrillation and its association with stroke and mortality after onset in 9511 participants enrolled in the Framingham Heart Study between 1958 and 2007. We analysed trends within 10 year groups (1958-67, 1968-77, 1978-87, 1988-97, and 1998-2007), stratified by sex. Findings During 50 years of observation (202 417 person-years), 1544 cases of new-onset atrial fibrillation occurred (of whom 723 [47%] were women). Between 1958-67 and 1998-2007, age-adjusted prevalence of atrial fibrillation quadrupled from 20·4 to 96·2 cases per 1000 person-years in men and from 13·7 to 49·4 cases per 1000 person-years in women; age-adjusted incidence increased from 3·7 to 13·4 new cases per 1000 person-years in men and from 2·5 to 8·6 new cases per 1000 person-years in women (ptrend<0·0001 for all comparisons). For atrial fibrillation diagnosed by electrocardiograph (ECG) during routine Framingham examinations, age-adjusted prevalence per 1000 person-years increased (12·6 in 1958-67 to 25·7 in 1998-2007 in men, ptrend=0·0007; 8·1 to 11·8 in women, ptrend=0·009). However, age-adjusted incidence of atrial fibrillation by Framingham Heart Study ECGs did not change significantly with time. Although the prevalence of most risk factors changed over time, their associated hazards for atrial fibrillation changed little. Multivariable-adjusted proportional hazards models revealed a 74% (95% CI 50-86%) decrease in stroke (hazards ratio [HR] 3·77, 95% CI 1·98-7·20 in 1958-1967 compared with 1998-2007; ptrend=0·0001) and a 25% (95% CI -3-46%) decrease in mortality (HR 1·34, 95% CI 0·97-1·86 in 1958-1967 compared with 1998-2007; ptrend=0·003) in 20 years following atrial fibrillation onset. Interpretation Trends of increased incidence and prevalence of atrial fibrillation in the community were probably partly due to enhanced surveillance. Measures are needed to enhance early detection of atrial fibrillation, through increased awareness coupled with targeted screening programmes and risk factor-specific prevention. Funding NIH, NHLBI, NINDS, Deutsche Forschungsgemeinschaft. Summary Background Comprehensive long-term data on atrial fibrillation trends in men and women are scant. We aimed to provide such data through analysis of the Framingham cohort over 50 years. Methods We investigated trends in incidence, prevalence, and risk factors for atrial fibrillation and its association with stroke and mortality after onset in 9511 participants enrolled in the Framingham Heart Study between 1958 and 2007. We analysed trends within 10 year groups (1958–67, 1968–77, 1978–87, 1988–97, and 1998–2007), stratified by sex. Findings During 50 years of observation (202 417 person-years), 1544 cases of new-onset atrial fibrillation occurred (of whom 723 [47%] were women). Between 1958–67 and 1998–2007, age-adjusted prevalence of atrial fibrillation quadrupled from 20·4 to 96·2 cases per 1000 person-years in men and from 13·7 to 49·4 cases per 1000 person-years in women; age-adjusted incidence increased from 3·7 to 13·4 new cases per 1000 person-years in men and from 2·5 to 8·6 new cases per 1000 person-years in women (ptrend <0·0001 for all comparisons). For atrial fibrillation diagnosed by electrocardiograph (ECG) during routine Framingham examinations, age-adjusted prevalence per 1000 person-years increased (12·6 in 1958–67 to 25·7 in 1998–2007 in men, ptrend =0·0007; 8·1 to 11·8 in women, ptrend =0·009). However, age-adjusted incidence of atrial fibrillation by Framingham Heart Study ECGs did not change significantly with time. Although the prevalence of most risk factors changed over time, their associated hazards for atrial fibrillation changed little. Multivariable-adjusted proportional hazards models revealed a 74% (95% CI 50–86%) decrease in stroke (hazards ratio [HR] 3·77, 95% CI 1·98–7·20 in 1958–1967 compared with 1998–2007; ptrend =0·0001) and a 25% (95% CI −3–46%) decrease in mortality (HR 1·34, 95% CI 0·97–1·86 in 1958–1967 compared with 1998–2007; ptrend =0·003) in 20 years following atrial fibrillation onset. Interpretation Trends of increased incidence and prevalence of atrial fibrillation in the community were probably partly due to enhanced surveillance. Measures are needed to enhance early detection of atrial fibrillation, through increased awareness coupled with targeted screening programmes and risk factor-specific prevention. Funding NIH, NHLBI, NINDS, Deutsche Forschungsgemeinschaft. Comprehensive long-term data on atrial fibrillation trends in men and women are scant. We aimed to provide such data through analysis of the Framingham cohort over 50 years.BACKGROUNDComprehensive long-term data on atrial fibrillation trends in men and women are scant. We aimed to provide such data through analysis of the Framingham cohort over 50 years.We investigated trends in incidence, prevalence, and risk factors for atrial fibrillation and its association with stroke and mortality after onset in 9511 participants enrolled in the Framingham Heart Study between 1958 and 2007. We analysed trends within 10 year groups (1958-67, 1968-77, 1978-87, 1988-97, and 1998-2007), stratified by sex.METHODSWe investigated trends in incidence, prevalence, and risk factors for atrial fibrillation and its association with stroke and mortality after onset in 9511 participants enrolled in the Framingham Heart Study between 1958 and 2007. We analysed trends within 10 year groups (1958-67, 1968-77, 1978-87, 1988-97, and 1998-2007), stratified by sex.During 50 years of observation (202,417 person-years), 1544 cases of new-onset atrial fibrillation occurred (of whom 723 [47%] were women). Between 1958-67 and 1998-2007, age-adjusted prevalence of atrial fibrillation quadrupled from 20·4 to 96·2 cases per 1000 person-years in men and from 13·7 to 49·4 cases per 1000 person-years in women; age-adjusted incidence increased from 3·7 to 13·4 new cases per 1000 person-years in men and from 2·5 to 8·6 new cases per 1000 person-years in women (ptrend<0·0001 for all comparisons). For atrial fibrillation diagnosed by electrocardiograph (ECG) during routine Framingham examinations, age-adjusted prevalence per 1000 person-years increased (12·6 in 1958-67 to 25·7 in 1998-2007 in men, ptrend=0·0007; 8·1 to 11·8 in women, ptrend=0·009). However, age-adjusted incidence of atrial fibrillation by Framingham Heart Study ECGs did not change significantly with time. Although the prevalence of most risk factors changed over time, their associated hazards for atrial fibrillation changed little. Multivariable-adjusted proportional hazards models revealed a 74% (95% CI 50-86%) decrease in stroke (hazards ratio [HR] 3·77, 95% CI 1·98-7·20 in 1958-1967 compared with 1998-2007; ptrend=0·0001) and a 25% (95% CI -3-46%) decrease in mortality (HR 1·34, 95% CI 0·97-1·86 in 1958-1967 compared with 1998-2007; ptrend=0·003) in 20 years following atrial fibrillation onset.FINDINGSDuring 50 years of observation (202,417 person-years), 1544 cases of new-onset atrial fibrillation occurred (of whom 723 [47%] were women). Between 1958-67 and 1998-2007, age-adjusted prevalence of atrial fibrillation quadrupled from 20·4 to 96·2 cases per 1000 person-years in men and from 13·7 to 49·4 cases per 1000 person-years in women; age-adjusted incidence increased from 3·7 to 13·4 new cases per 1000 person-years in men and from 2·5 to 8·6 new cases per 1000 person-years in women (ptrend<0·0001 for all comparisons). For atrial fibrillation diagnosed by electrocardiograph (ECG) during routine Framingham examinations, age-adjusted prevalence per 1000 person-years increased (12·6 in 1958-67 to 25·7 in 1998-2007 in men, ptrend=0·0007; 8·1 to 11·8 in women, ptrend=0·009). However, age-adjusted incidence of atrial fibrillation by Framingham Heart Study ECGs did not change significantly with time. Although the prevalence of most risk factors changed over time, their associated hazards for atrial fibrillation changed little. Multivariable-adjusted proportional hazards models revealed a 74% (95% CI 50-86%) decrease in stroke (hazards ratio [HR] 3·77, 95% CI 1·98-7·20 in 1958-1967 compared with 1998-2007; ptrend=0·0001) and a 25% (95% CI -3-46%) decrease in mortality (HR 1·34, 95% CI 0·97-1·86 in 1958-1967 compared with 1998-2007; ptrend=0·003) in 20 years following atrial fibrillation onset.Trends of increased incidence and prevalence of atrial fibrillation in the community were probably partly due to enhanced surveillance. Measures are needed to enhance early detection of atrial fibrillation, through increased awareness coupled with targeted screening programmes and risk factor-specific prevention.INTERPRETATIONTrends of increased incidence and prevalence of atrial fibrillation in the community were probably partly due to enhanced surveillance. Measures are needed to enhance early detection of atrial fibrillation, through increased awareness coupled with targeted screening programmes and risk factor-specific prevention.NIH, NHLBI, NINDS, Deutsche Forschungsgemeinschaft.FUNDINGNIH, NHLBI, NINDS, Deutsche Forschungsgemeinschaft. |
| Author | Schnabel, Renate B Vasan, Ramachandran S Wolf, Philip A Benjamin, Emelia J Ellinor, Patrick T Seshadri, Sudha Magnani, Jared W Beiser, Alexa S Yin, Xiaoyan Larson, Martin G McManus, David D Levy, Daniel Lubitz, Steven A Newton-Cheh, Christopher Gona, Philimon |
| Author_xml | – sequence: 1 givenname: Renate B surname: Schnabel fullname: Schnabel, Renate B email: r.schnabel@uke.de organization: National Heart, Lung, and Blood Institute's Framingham Study, Framingham, MA, USA – sequence: 2 givenname: Xiaoyan surname: Yin fullname: Yin, Xiaoyan organization: National Heart, Lung, and Blood Institute's Framingham Study, Framingham, MA, USA – sequence: 3 givenname: Philimon surname: Gona fullname: Gona, Philimon organization: National Heart, Lung, and Blood Institute's Framingham Study, Framingham, MA, USA – sequence: 4 givenname: Martin G surname: Larson fullname: Larson, Martin G organization: National Heart, Lung, and Blood Institute's Framingham Study, Framingham, MA, USA – sequence: 5 givenname: Alexa S surname: Beiser fullname: Beiser, Alexa S organization: National Heart, Lung, and Blood Institute's Framingham Study, Framingham, MA, USA – sequence: 6 givenname: David D surname: McManus fullname: McManus, David D organization: Cardiology Division, Department of Medicine, University of Massachusetts Medical School, Boston, MA, USA – sequence: 7 givenname: Christopher surname: Newton-Cheh fullname: Newton-Cheh, Christopher organization: National Heart, Lung, and Blood Institute's Framingham Study, Framingham, MA, USA – sequence: 8 givenname: Steven A surname: Lubitz fullname: Lubitz, Steven A organization: Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA – sequence: 9 givenname: Jared W surname: Magnani fullname: Magnani, Jared W organization: Cardiology Section, School of Medicine, Boston University, Boston, MA, USA – sequence: 10 givenname: Patrick T surname: Ellinor fullname: Ellinor, Patrick T organization: Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA – sequence: 11 givenname: Sudha surname: Seshadri fullname: Seshadri, Sudha organization: National Heart, Lung, and Blood Institute's Framingham Study, Framingham, MA, USA – sequence: 12 givenname: Philip A surname: Wolf fullname: Wolf, Philip A organization: National Heart, Lung, and Blood Institute's Framingham Study, Framingham, MA, USA – sequence: 13 givenname: Ramachandran S surname: Vasan fullname: Vasan, Ramachandran S organization: National Heart, Lung, and Blood Institute's Framingham Study, Framingham, MA, USA – sequence: 14 givenname: Emelia J surname: Benjamin fullname: Benjamin, Emelia J organization: National Heart, Lung, and Blood Institute's Framingham Study, Framingham, MA, USA – sequence: 15 givenname: Daniel surname: Levy fullname: Levy, Daniel organization: National Heart, Lung, and Blood Institute's Framingham Study, Framingham, MA, USA |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/25960110$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNkV9r1TAYh4NM3Nn0IygBbzZYNWmT_lGcyHBOGHixXXgX3iapJ1ubHJN00C_g5zY9nRMOyLxKAs_vSfL-DtCedVYj9JKSN5TQ8u0VoYxkZVWUR5Qdl7SqWFY_QSvK0oaz6vseWj0g--gghBtCCCsJf4b2c96UhFKyQr84wZMGj6PXVgVsLIboDfS4M603fQ_ROIs3Xt9Br63UJwmRRi1bb8It7kBG58MJBqvw4HyE3sRpNsW1xuceBmN_rGHAF-meiK_iqKZ3GLB06wTjMJ-fo6cd9EG_uF8P0fX55-uzi-zy25evZ58uM8mrPGY58JxJKAqZUy4L3rSQ15zRTnWNKroaipYVKqENV11NmoqwppDQdNC0OuUO0dGi3Xj3c9QhisEEqdMvrXZjELRsapJXnPOEvt5Bb9zobXrcTPG8IJw2iXp1T43toJXYeDOAn8SfASeAL4D0LgSvuweEEjEXKbZFirklQZnYFinqlHu_k5MmbruIHkz_aPrjktZplndGexGkmStTxmsZhXLmUcPpjkH2xhoJ_a2edPg7CxFyQRbJ7KBsa5gFH_4t-I8H_Aa4Yt8k |
| CODEN | LANCAO |
| CitedBy_id | crossref_primary_10_1002_adfm_201600008 crossref_primary_10_1007_s00380_017_1019_y crossref_primary_10_1161_CIRCEP_118_006350 crossref_primary_10_3390_cells11172629 crossref_primary_10_4274_nkmj_galenos_2022_31932 crossref_primary_10_1007_s12325_024_02895_w crossref_primary_10_1016_j_rce_2019_04_001 crossref_primary_10_3390_antiox11050932 crossref_primary_10_3390_jcm13082318 crossref_primary_10_1038_s41569_022_00820_8 crossref_primary_10_3892_mmr_2018_9695 crossref_primary_10_1016_j_cmpb_2019_05_005 crossref_primary_10_1016_j_jemermed_2024_06_010 crossref_primary_10_1016_j_hroo_2025_02_002 crossref_primary_10_1186_s12872_022_02773_9 crossref_primary_10_1186_s12933_023_01767_x crossref_primary_10_1111_pace_14201 crossref_primary_10_1016_j_jjcc_2025_03_002 crossref_primary_10_1055_s_0041_1731772 crossref_primary_10_1007_s40261_016_0487_7 crossref_primary_10_3389_fnut_2024_1369594 crossref_primary_10_1002_prp2_1012 crossref_primary_10_1016_j_jacasi_2025_05_006 crossref_primary_10_3389_fphys_2018_01251 crossref_primary_10_1093_eurheartj_ehy528 crossref_primary_10_1016_j_ijcard_2021_11_008 crossref_primary_10_1016_j_jfma_2024_01_012 crossref_primary_10_1161_JAHA_117_007584 crossref_primary_10_1016_j_hfc_2020_06_005 crossref_primary_10_1093_jamiaopen_ooad003 crossref_primary_10_1080_13543784_2024_2388583 crossref_primary_10_3389_fnins_2025_1525027 crossref_primary_10_1016_j_jacc_2018_05_048 crossref_primary_10_1111_jce_70063 crossref_primary_10_3390_jcm10112321 crossref_primary_10_1016_j_jacc_2018_04_013 crossref_primary_10_35336_VA_1428 crossref_primary_10_1097_FJC_0000000000000697 crossref_primary_10_1016_j_thromres_2020_08_021 crossref_primary_10_1038_nrcardio_2017_107 crossref_primary_10_2147_VHRM_S534357 crossref_primary_10_1016_j_atherosclerosis_2018_02_004 crossref_primary_10_1590_1516_3180_2018_1364110718 crossref_primary_10_3390_geriatrics9010015 crossref_primary_10_1016_j_clnu_2025_03_001 crossref_primary_10_1002_ehf2_14035 crossref_primary_10_1136_openhrt_2019_001185 crossref_primary_10_1016_j_jjcc_2019_05_014 crossref_primary_10_1186_s13054_024_05138_0 crossref_primary_10_1016_j_jacep_2020_08_041 crossref_primary_10_1016_j_hrthm_2017_02_024 crossref_primary_10_1111_jce_15446 crossref_primary_10_1016_j_hrthm_2024_09_032 crossref_primary_10_1161_CIR_0000000000000659 crossref_primary_10_1016_j_ejim_2020_04_021 crossref_primary_10_1080_14740338_2024_2337741 crossref_primary_10_1080_14779072_2019_1550720 crossref_primary_10_1093_eurheartj_ehae373 crossref_primary_10_1161_CIRCEP_123_012143 crossref_primary_10_1161_STROKEAHA_116_013988 crossref_primary_10_3389_fcvm_2023_1243574 crossref_primary_10_1111_apha_14228 crossref_primary_10_1016_j_repce_2015_07_014 crossref_primary_10_1186_s12875_025_02905_y crossref_primary_10_1016_j_rce_2022_11_004 crossref_primary_10_1038_s44387_025_00022_w crossref_primary_10_1016_j_jacc_2018_05_066 crossref_primary_10_1016_j_amjcard_2023_07_001 crossref_primary_10_1093_ehjqcco_qcae007 crossref_primary_10_3390_jcdd9070224 crossref_primary_10_1016_j_jacc_2016_01_048 crossref_primary_10_1111_ggi_13318 crossref_primary_10_1111_jce_70009 crossref_primary_10_1161_CIRCULATIONAHA_124_071047 crossref_primary_10_1093_eurheartj_ehw134 crossref_primary_10_1080_14656566_2019_1621290 crossref_primary_10_1097_MD_0000000000007253 crossref_primary_10_1016_j_iccl_2017_12_005 crossref_primary_10_1186_s42444_024_00122_9 crossref_primary_10_1161_JAHA_124_037959 crossref_primary_10_1016_j_jacc_2018_05_076 crossref_primary_10_7759_cureus_63795 crossref_primary_10_4997_jrcpe_2017_105 crossref_primary_10_1155_2021_5516185 crossref_primary_10_1038_s41433_025_03956_2 crossref_primary_10_3390_ijms23147886 crossref_primary_10_3389_fcvm_2022_890481 crossref_primary_10_1111_pace_14643 crossref_primary_10_1097_HJH_0000000000003291 crossref_primary_10_3390_medicina57080776 crossref_primary_10_1097_MD_0000000000029038 crossref_primary_10_3390_s24144432 crossref_primary_10_1038_s41598_018_24878_y crossref_primary_10_1161_JAHA_122_026240 crossref_primary_10_3390_jcm10071514 crossref_primary_10_1161_CIRCULATIONAHA_117_028981 crossref_primary_10_1139_apnm_2024_0060 crossref_primary_10_1186_s12872_019_1249_2 crossref_primary_10_1016_j_jjcc_2024_09_001 crossref_primary_10_1093_ehjqcco_qcac086 crossref_primary_10_3389_fnins_2018_01058 crossref_primary_10_3390_diseases12020038 crossref_primary_10_1007_s13239_024_00738_x crossref_primary_10_1007_s11886_016_0735_8 crossref_primary_10_1038_s41598_021_96820_8 crossref_primary_10_1016_j_ccep_2019_11_009 crossref_primary_10_1097_HPC_0000000000000295 crossref_primary_10_1111_jce_16108 crossref_primary_10_1016_j_thromres_2017_08_004 crossref_primary_10_1016_j_tcm_2020_10_010 crossref_primary_10_1002_clc_23371 crossref_primary_10_1093_ehjcvp_pvy009 crossref_primary_10_3389_fimmu_2021_638867 crossref_primary_10_1016_j_ahj_2016_07_027 crossref_primary_10_3390_jcm14113857 crossref_primary_10_1136_postgradmedj_2019_136842 crossref_primary_10_3389_fmed_2025_1528195 crossref_primary_10_1016_j_ijcard_2018_03_050 crossref_primary_10_3389_fcvm_2023_1195123 crossref_primary_10_1136_bmjopen_2023_083153 crossref_primary_10_1159_000533361 crossref_primary_10_7759_cureus_71186 crossref_primary_10_1007_s10554_021_02244_w crossref_primary_10_1016_j_amjcard_2018_03_028 crossref_primary_10_1155_2017_9232658 crossref_primary_10_1111_jan_14164 crossref_primary_10_1111_jcmm_70618 crossref_primary_10_1371_journal_pone_0310951 crossref_primary_10_1016_j_hrthm_2017_01_032 crossref_primary_10_1016_j_repc_2024_12_008 crossref_primary_10_2147_DDDT_S293812 crossref_primary_10_1080_14017431_2025_2526044 crossref_primary_10_1161_JAHA_117_007129 crossref_primary_10_1161_CIRCEP_120_009355 crossref_primary_10_1097_FJC_0000000000001360 crossref_primary_10_1177_1756284819832237 crossref_primary_10_1016_j_jacep_2025_07_011 crossref_primary_10_1080_08998280_2017_11929615 crossref_primary_10_1080_03007995_2024_2332440 crossref_primary_10_1097_CM9_0000000000003501 crossref_primary_10_3389_fcvm_2025_1587547 crossref_primary_10_1111_apha_12895 crossref_primary_10_1080_03007995_2020_1865748 crossref_primary_10_1097_JCN_0000000000000769 crossref_primary_10_1111_jce_14181 crossref_primary_10_1016_j_ejim_2017_05_008 crossref_primary_10_1111_jce_14183 crossref_primary_10_2147_CLEP_S374468 crossref_primary_10_1186_s13020_023_00812_x crossref_primary_10_1016_j_acvd_2017_07_005 crossref_primary_10_1159_000529260 crossref_primary_10_1186_s40001_024_01952_y crossref_primary_10_1016_j_eehl_2024_05_006 crossref_primary_10_1212_WNL_0000000000003321 crossref_primary_10_1016_j_jcin_2015_07_036 crossref_primary_10_1016_j_scitotenv_2021_147106 crossref_primary_10_1093_eurheartj_ehae198 crossref_primary_10_1161_CIR_0000000000001123 crossref_primary_10_1093_cvr_cvae067 crossref_primary_10_1186_s12872_024_04349_1 crossref_primary_10_3389_fendo_2019_00584 crossref_primary_10_1186_s12951_024_02805_w crossref_primary_10_1001_jamanetworkopen_2022_55838 crossref_primary_10_1016_j_clml_2016_09_010 crossref_primary_10_1002_clc_23147 crossref_primary_10_1016_j_mayocp_2023_01_007 crossref_primary_10_1016_j_ijcard_2017_09_208 crossref_primary_10_2196_64259 crossref_primary_10_1016_j_ijcard_2023_04_007 crossref_primary_10_3390_ijms242115699 crossref_primary_10_3390_jcm10143021 crossref_primary_10_1097_CM9_0000000000002627 crossref_primary_10_1186_s12944_023_01952_7 crossref_primary_10_1016_j_mayocp_2023_04_016 crossref_primary_10_1055_s_0041_1726332 crossref_primary_10_1161_CIR_0000000000000485 crossref_primary_10_1007_s00392_023_02349_3 crossref_primary_10_1016_j_ijcard_2025_133385 crossref_primary_10_1097_JXX_0000000000000424 crossref_primary_10_1016_j_ijcard_2018_10_020 crossref_primary_10_1097_HPC_0000000000000257 crossref_primary_10_1016_j_jacc_2021_11_066 crossref_primary_10_1016_j_ijcard_2018_10_024 crossref_primary_10_1109_ACCESS_2024_3467181 crossref_primary_10_3389_fcvm_2023_1060030 crossref_primary_10_1161_JAHA_119_014287 crossref_primary_10_37586_2686_8636_2_2020_138_146 crossref_primary_10_1002_clc_70115 crossref_primary_10_1093_eurheartj_ehaa612 crossref_primary_10_1053_j_jvca_2019_01_054 crossref_primary_10_1136_bmj_m2724 crossref_primary_10_1186_s12872_022_02973_3 crossref_primary_10_17802_2306_1278_2025_14_1_132_143 crossref_primary_10_1080_22423982_2022_2030522 crossref_primary_10_1016_j_jacc_2019_10_040 crossref_primary_10_1093_ehjqcco_qcaa040 crossref_primary_10_1016_j_ijcard_2020_06_018 crossref_primary_10_1161_CIRCULATIONAHA_116_025312 crossref_primary_10_1038_s41598_025_10004_2 crossref_primary_10_1097_MD_0000000000027749 crossref_primary_10_1016_j_ahj_2016_05_004 crossref_primary_10_1109_JSEN_2025_3572716 crossref_primary_10_1007_s00392_019_01437_7 crossref_primary_10_3390_biology11040530 crossref_primary_10_1161_JAHA_123_032378 crossref_primary_10_1007_s10654_019_00594_3 crossref_primary_10_1016_j_jacasi_2025_04_008 crossref_primary_10_1093_eurjpc_zwab005 crossref_primary_10_1007_s12975_020_00822_z crossref_primary_10_1177_1721727X221094426 crossref_primary_10_1016_j_hrthm_2020_04_033 crossref_primary_10_1093_ehjqcco_qcac013 crossref_primary_10_1002_clc_70186 crossref_primary_10_1177_23969873231222393 crossref_primary_10_2459_JCM_0000000000001552 crossref_primary_10_1016_j_jjcc_2022_08_012 crossref_primary_10_1093_eurheartj_ehaf005 crossref_primary_10_3389_fcvm_2024_1359922 crossref_primary_10_1007_s40264_018_0695_6 crossref_primary_10_1016_j_cjca_2017_11_022 crossref_primary_10_1016_j_jacasi_2025_04_003 crossref_primary_10_2147_DMSO_S274047 crossref_primary_10_1177_1747493021995592 crossref_primary_10_1001_jama_2024_22451 crossref_primary_10_1001_jamanetworkopen_2022_29333 crossref_primary_10_1111_jce_16393 crossref_primary_10_1136_heartjnl_2024_324274 crossref_primary_10_1186_s12879_019_4150_9 crossref_primary_10_1016_j_hrthm_2024_09_014 crossref_primary_10_1038_s41598_021_84307_5 crossref_primary_10_1371_journal_pone_0281818 crossref_primary_10_1186_s12944_021_01551_4 crossref_primary_10_1016_j_hrthm_2025_02_013 crossref_primary_10_15829_1560_4071_2022_5026 crossref_primary_10_1093_eurheartj_ehaa822 crossref_primary_10_3389_fphys_2018_00835 crossref_primary_10_1016_j_ccep_2020_10_010 crossref_primary_10_1016_j_ccep_2023_09_001 crossref_primary_10_1016_j_jjcc_2022_08_006 crossref_primary_10_1093_ehjqcco_qcaa092 crossref_primary_10_1016_j_jns_2017_05_022 crossref_primary_10_1111_imj_15253 crossref_primary_10_1016_j_jacc_2023_08_017 crossref_primary_10_1161_CIRCGEN_120_003111 crossref_primary_10_1016_j_hlc_2023_12_016 crossref_primary_10_1016_j_ijcard_2016_01_007 crossref_primary_10_1088_1361_6579_ad37ee crossref_primary_10_1016_j_cyto_2021_155557 crossref_primary_10_1016_j_jacc_2024_01_013 crossref_primary_10_1016_j_ahj_2016_11_008 crossref_primary_10_1161_JAHA_116_003776 crossref_primary_10_1161_JAHA_122_025303 crossref_primary_10_1007_s40520_018_0932_y crossref_primary_10_1093_eurheartj_ehz234 crossref_primary_10_1111_dom_15714 crossref_primary_10_1093_eurheartj_ehae176 crossref_primary_10_1016_j_amjcard_2017_08_014 crossref_primary_10_3390_jcm10235497 crossref_primary_10_1136_bmjopen_2025_102160 crossref_primary_10_1002_joa3_12714 crossref_primary_10_2196_43123 crossref_primary_10_3389_fbioe_2023_1011121 crossref_primary_10_5334_aogh_3252 crossref_primary_10_1111_ans_15486 crossref_primary_10_1136_openhrt_2020_001298 crossref_primary_10_1016_j_clinthera_2023_03_008 crossref_primary_10_1111_pace_13500 crossref_primary_10_3390_jpm13091323 crossref_primary_10_1002_ccd_27720 crossref_primary_10_1016_j_gene_2025_149307 crossref_primary_10_1016_j_medcli_2021_11_013 crossref_primary_10_1016_j_ccep_2021_04_009 crossref_primary_10_1097_HJH_0000000000001228 crossref_primary_10_1016_j_jacasi_2022_11_004 crossref_primary_10_1136_bmjopen_2018_022092 crossref_primary_10_1016_j_hlc_2018_06_1043 crossref_primary_10_1016_j_jacep_2016_10_008 crossref_primary_10_1186_s12866_020_01734_6 crossref_primary_10_1016_j_amjcard_2021_08_065 crossref_primary_10_1073_pnas_2302708120 crossref_primary_10_1016_j_ccep_2024_10_001 crossref_primary_10_1161_CIRCRESAHA_125_325612 crossref_primary_10_7759_cureus_59519 crossref_primary_10_1080_03007995_2024_2365999 crossref_primary_10_3390_jcm12072650 crossref_primary_10_1016_j_hroo_2024_12_015 crossref_primary_10_1016_j_atherosclerosis_2017_12_026 crossref_primary_10_3389_fcvm_2023_1258167 crossref_primary_10_3389_fcvm_2024_1392548 crossref_primary_10_1016_j_exger_2018_09_006 crossref_primary_10_1016_j_rceng_2022_11_005 crossref_primary_10_1111_imj_13648 crossref_primary_10_1186_s12872_022_02580_2 crossref_primary_10_3389_fcvm_2024_1388024 crossref_primary_10_1016_j_numecd_2024_03_027 crossref_primary_10_18203_2320_6012_ijrms20252383 crossref_primary_10_1016_j_jaccao_2021_03_006 crossref_primary_10_1093_eurheartj_suaa166 crossref_primary_10_1161_CIRCULATIONAHA_117_031431 crossref_primary_10_1016_j_thromres_2025_109337 crossref_primary_10_1371_journal_pone_0275103 crossref_primary_10_1016_j_jemermed_2017_11_016 crossref_primary_10_3390_pharmaceutics15082107 crossref_primary_10_3389_fcvm_2024_1346414 crossref_primary_10_1097_CM9_0000000000001151 crossref_primary_10_1093_ehjopen_oeaf063 crossref_primary_10_3390_jpm12071186 crossref_primary_10_1093_aje_kwx068 crossref_primary_10_1177_0004563218788386 crossref_primary_10_1016_j_amjcard_2015_10_031 crossref_primary_10_1371_journal_pntd_0011419 crossref_primary_10_3389_fphys_2018_01847 crossref_primary_10_1097_MS9_0000000000003364 crossref_primary_10_1111_jce_13958 crossref_primary_10_1371_journal_pone_0247097 crossref_primary_10_17802_2306_1278_2025_14_1_60_73 crossref_primary_10_1136_heartjnl_2021_319853 crossref_primary_10_1177_2047487316676037 crossref_primary_10_1055_s_0043_1769612 crossref_primary_10_1161_HYPERTENSIONAHA_116_07683 crossref_primary_10_1016_j_ajpc_2025_101018 crossref_primary_10_1016_j_jns_2021_117410 crossref_primary_10_1002_sim_70093 crossref_primary_10_1161_JAHA_122_027089 crossref_primary_10_1097_MEG_0000000000002562 crossref_primary_10_1016_j_ando_2020_02_006 crossref_primary_10_1177_2047487318759853 crossref_primary_10_1093_eurheartj_ehz037 crossref_primary_10_1016_j_tcm_2023_11_005 crossref_primary_10_1016_j_measurement_2025_118777 crossref_primary_10_1371_journal_pone_0163608 crossref_primary_10_1186_s13104_022_06173_2 crossref_primary_10_1038_s41684_023_01141_0 crossref_primary_10_3390_jcm14082648 crossref_primary_10_1016_j_heliyon_2024_e25295 crossref_primary_10_15829_1728_8800_2019_3_81_87 crossref_primary_10_1038_s41440_024_01796_3 crossref_primary_10_1016_j_yjmcc_2021_04_003 crossref_primary_10_1177_2047487318769412 crossref_primary_10_1007_s00392_018_1361_9 crossref_primary_10_1002_rth2_12823 crossref_primary_10_2459_JCM_0000000000000986 crossref_primary_10_7759_cureus_34026 crossref_primary_10_1001_jamanetworkopen_2020_14874 crossref_primary_10_3390_jpm12030437 crossref_primary_10_1016_j_hrthm_2024_04_048 crossref_primary_10_1161_JAHA_124_038367 crossref_primary_10_1109_LRA_2017_2676351 crossref_primary_10_3390_jcm12206566 crossref_primary_10_1016_j_ijcard_2024_132393 crossref_primary_10_1111_anae_14118 crossref_primary_10_1161_HAE_0000000000000078 crossref_primary_10_1161_CIRCEP_116_004378 crossref_primary_10_1016_j_ijcard_2024_132397 crossref_primary_10_1371_journal_pone_0289708 crossref_primary_10_1016_j_jacc_2016_09_940 crossref_primary_10_1016_j_jacep_2017_03_007 crossref_primary_10_1007_s10840_020_00878_9 crossref_primary_10_1111_chd_12859 crossref_primary_10_1093_cvr_cvab153 crossref_primary_10_1111_ggi_70089 crossref_primary_10_1016_j_jns_2019_05_012 crossref_primary_10_1097_MD_0000000000018937 crossref_primary_10_3389_fnagi_2022_836425 crossref_primary_10_1161_CIR_0000000000001052 crossref_primary_10_1016_j_pcad_2025_07_006 crossref_primary_10_3390_jcm11092660 crossref_primary_10_3390_jcm12206559 crossref_primary_10_22159_ijap_2025_v17s2_14 crossref_primary_10_3390_jcdd11040097 crossref_primary_10_1016_j_jelectrocard_2024_01_005 crossref_primary_10_3389_fnut_2022_1086715 crossref_primary_10_1016_j_jacadv_2024_101330 crossref_primary_10_1016_j_rceng_2019_04_002 crossref_primary_10_3390_jcm13072132 crossref_primary_10_1016_j_ecl_2024_10_005 crossref_primary_10_2459_JCM_0000000000000524 crossref_primary_10_1016_j_cca_2015_05_017 crossref_primary_10_1161_CIRCRESAHA_120_316402 crossref_primary_10_1161_JAHA_118_010153 crossref_primary_10_1016_j_numecd_2024_01_012 crossref_primary_10_1016_j_amjcard_2021_08_042 crossref_primary_10_1161_JAHA_123_033840 crossref_primary_10_4070_kcj_2024_0385 crossref_primary_10_1038_srep40377 crossref_primary_10_1177_2048004020915406 crossref_primary_10_1016_j_jchf_2022_01_018 crossref_primary_10_3389_fcvm_2022_970847 crossref_primary_10_1007_s00392_020_01797_5 crossref_primary_10_1016_j_jjcc_2016_12_004 crossref_primary_10_1097_CRD_0000000000000531 crossref_primary_10_1016_j_jacep_2024_02_016 crossref_primary_10_1053_j_jvca_2019_02_034 crossref_primary_10_23736_S2724_5683_24_06492_5 crossref_primary_10_3389_fcvm_2020_615065 crossref_primary_10_1161_CIRCRESAHA_122_320258 crossref_primary_10_3390_brainsci13111541 crossref_primary_10_1111_jce_14838 crossref_primary_10_1038_s41572_022_00347_9 crossref_primary_10_3390_nu11071651 crossref_primary_10_1038_nrneph_2018_19 crossref_primary_10_1371_journal_pone_0206362 crossref_primary_10_1002_ehf2_12464 crossref_primary_10_12998_wjcc_v10_i4_1357 crossref_primary_10_1093_eurjpc_zwad283 crossref_primary_10_1080_24748706_2019_1643957 crossref_primary_10_1007_s00392_017_1171_5 crossref_primary_10_1155_ijcp_5272962 crossref_primary_10_1016_j_amjmed_2022_11_009 crossref_primary_10_1038_srep34708 crossref_primary_10_1136_bmjopen_2021_059156 crossref_primary_10_1016_j_hrthm_2015_07_031 crossref_primary_10_1007_s10439_017_1832_6 crossref_primary_10_1016_j_amjcard_2019_01_056 crossref_primary_10_1016_j_ancard_2023_101616 crossref_primary_10_1093_icvts_ivw088 crossref_primary_10_1007_s00392_022_02117_9 crossref_primary_10_1093_eurheartj_ehab250 crossref_primary_10_1161_HYPERTENSIONAHA_116_08956 crossref_primary_10_3389_fcvm_2024_1400643 crossref_primary_10_1016_j_jacep_2022_10_023 crossref_primary_10_1186_s12872_021_01951_5 crossref_primary_10_1371_journal_pone_0273571 crossref_primary_10_1371_journal_pmed_1003405 crossref_primary_10_1136_bmjopen_2023_081808 crossref_primary_10_3390_clinpract14010027 crossref_primary_10_1161_CIRCIMAGING_122_014386 crossref_primary_10_3389_fcvm_2025_1581683 crossref_primary_10_2147_CIA_S464044 crossref_primary_10_1016_j_jjcc_2017_07_008 crossref_primary_10_1111_jocs_16312 crossref_primary_10_1161_CIRCRESAHA_122_322213 crossref_primary_10_1186_s12880_025_01740_y crossref_primary_10_1007_s00380_021_01908_w crossref_primary_10_1161_JAHA_120_016810 crossref_primary_10_1016_j_bspc_2020_102264 crossref_primary_10_1186_s13062_025_00618_x crossref_primary_10_1016_j_jacc_2017_03_558 crossref_primary_10_1007_s12471_020_01447_5 crossref_primary_10_1016_j_carrev_2019_08_001 crossref_primary_10_1016_S0140_6736_19_31721_0 crossref_primary_10_1002_joa3_12338 crossref_primary_10_1016_j_repc_2023_11_005 crossref_primary_10_3389_fcvm_2023_1068562 crossref_primary_10_1016_j_numecd_2024_05_023 crossref_primary_10_1002_adfm_202302041 crossref_primary_10_1093_europace_eux178 crossref_primary_10_2196_12179 crossref_primary_10_3390_jcm12031050 crossref_primary_10_1093_eurheartj_ehac364 crossref_primary_10_1017_S1047951122002827 crossref_primary_10_4103_aca_ACA_30_20 crossref_primary_10_1016_j_ijcard_2024_132375 crossref_primary_10_3390_jcm10112277 crossref_primary_10_1093_europace_euae291 crossref_primary_10_1007_s11883_022_01041_7 crossref_primary_10_1002_ejhf_1918 crossref_primary_10_12968_hmed_2020_0584 crossref_primary_10_1007_s10840_023_01555_3 crossref_primary_10_1093_eurheartj_ehaf623 crossref_primary_10_1093_ehjcvp_pvw022 crossref_primary_10_1053_j_jvca_2022_07_013 crossref_primary_10_1002_clc_22630 crossref_primary_10_1016_j_clnu_2020_04_025 crossref_primary_10_1002_iid3_1003 crossref_primary_10_3389_fcvm_2024_1303540 crossref_primary_10_1007_s00392_023_02330_0 crossref_primary_10_1016_j_ahj_2025_07_011 crossref_primary_10_1016_j_aichem_2023_100009 crossref_primary_10_1136_openhrt_2022_002140 crossref_primary_10_1002_rth2_12668 crossref_primary_10_1016_j_hrthm_2024_07_094 crossref_primary_10_3389_fcvm_2022_1023732 crossref_primary_10_1155_2022_1527292 crossref_primary_10_1111_jce_15759 crossref_primary_10_1007_s00399_017_0484_4 crossref_primary_10_3390_jcm13020314 crossref_primary_10_1016_j_mayocp_2024_09_010 crossref_primary_10_1016_j_amjms_2025_03_004 crossref_primary_10_1097_MD_0000000000040474 crossref_primary_10_1093_eurheartj_sux007 crossref_primary_10_3390_antiox9101012 crossref_primary_10_7759_cureus_74039 crossref_primary_10_1111_aas_14360 crossref_primary_10_1016_j_tcm_2020_12_002 crossref_primary_10_3892_ijmm_2024_5457 crossref_primary_10_1016_j_jacep_2022_11_032 crossref_primary_10_1016_j_ijcard_2017_06_004 crossref_primary_10_1002_joa3_13220 crossref_primary_10_1097_MD_0000000000031778 crossref_primary_10_1016_j_heliyon_2024_e35067 crossref_primary_10_3390_jcm12031224 crossref_primary_10_1161_CIRCULATIONAHA_115_021275 crossref_primary_10_3390_jcm10163622 crossref_primary_10_1016_j_ijcard_2018_01_044 crossref_primary_10_1016_j_jtha_2022_12_016 crossref_primary_10_1186_s12933_024_02194_2 crossref_primary_10_4081_cardio_2025_72 crossref_primary_10_3390_nu14091878 crossref_primary_10_1182_bloodadvances_2021005621 crossref_primary_10_1002_joa3_12378 crossref_primary_10_1136_openhrt_2022_002169 crossref_primary_10_1161_CIRCULATIONAHA_116_023519 crossref_primary_10_1016_j_jacep_2022_11_021 crossref_primary_10_2337_dc22_1655 crossref_primary_10_1016_j_nurpra_2021_07_018 crossref_primary_10_1097_HJH_0000000000003223 crossref_primary_10_1136_bmj_2021_058568 crossref_primary_10_1111_anec_12739 crossref_primary_10_1177_03000605211014375 crossref_primary_10_1093_ajh_hpx013 crossref_primary_10_1016_j_amolm_2023_100029 crossref_primary_10_3389_fnagi_2021_706815 crossref_primary_10_1111_jsr_12702 crossref_primary_10_1093_eurheartj_ehy815 crossref_primary_10_1161_JAHA_124_038742 crossref_primary_10_1186_s12916_021_02037_x crossref_primary_10_36660_abc_20230091 crossref_primary_10_1016_j_radonc_2018_11_008 crossref_primary_10_1097_QAD_0000000000002327 crossref_primary_10_1111_echo_14478 crossref_primary_10_3389_fcvm_2025_1540750 crossref_primary_10_1111_dom_16238 crossref_primary_10_1007_s12170_022_00709_8 crossref_primary_10_1007_s40291_024_00698_x crossref_primary_10_1016_j_ajem_2020_06_018 crossref_primary_10_1136_heartjnl_2024_323950 crossref_primary_10_1016_j_cpcardiol_2021_100996 crossref_primary_10_1093_europace_euw295 crossref_primary_10_1161_CIRCEP_121_009925 crossref_primary_10_3389_fphys_2019_00135 crossref_primary_10_1186_s12872_019_1150_z crossref_primary_10_3748_wjg_v25_i22_2788 crossref_primary_10_1097_CRD_0000000000000938 crossref_primary_10_1007_s12265_019_09918_w crossref_primary_10_1007_s11886_023_01961_z crossref_primary_10_20996_1819_6446_2025_3157 crossref_primary_10_1093_cvr_cvaa241 crossref_primary_10_1111_jce_15768 crossref_primary_10_1016_j_amjcard_2018_05_015 crossref_primary_10_1016_j_ihj_2019_07_009 crossref_primary_10_1097_MD_0000000000019897 crossref_primary_10_3390_reports6010015 crossref_primary_10_1136_bmj_2023_077209 crossref_primary_10_1016_j_arr_2020_101092 crossref_primary_10_3390_ijerph17093093 crossref_primary_10_1001_jama_2021_21811 crossref_primary_10_5334_gh_1023 crossref_primary_10_3390_diagnostics14141570 crossref_primary_10_1093_eurheartj_ehw210 crossref_primary_10_1080_14779072_2023_2254679 crossref_primary_10_1111_jce_14220 crossref_primary_10_1016_j_carrev_2019_07_022 crossref_primary_10_1016_j_jelectrocard_2023_09_011 crossref_primary_10_1007_s00380_022_02115_x crossref_primary_10_1016_j_hrthm_2018_11_016 crossref_primary_10_1177_1556984520960116 crossref_primary_10_1093_ejcts_ezw313 crossref_primary_10_1001_jamanetworkopen_2023_9973 crossref_primary_10_1093_europace_euae227 crossref_primary_10_1016_j_niox_2025_06_006 crossref_primary_10_1161_CIRCEP_119_007607 crossref_primary_10_1016_j_ijcard_2018_11_123 crossref_primary_10_3390_jpm12081306 crossref_primary_10_1016_j_ceh_2024_03_001 crossref_primary_10_1161_STROKEAHA_121_038285 crossref_primary_10_1177_20420986241312497 crossref_primary_10_1161_CIR_0000000000000558 crossref_primary_10_1161_CIRCEP_116_004738 crossref_primary_10_1007_s11906_019_0928_9 crossref_primary_10_1136_bmjopen_2017_017909 crossref_primary_10_3389_fcvm_2022_837958 crossref_primary_10_1182_bloodadvances_2017009720 crossref_primary_10_1016_j_jaccao_2023_03_007 crossref_primary_10_3390_jpm12010122 crossref_primary_10_1111_pace_14331 crossref_primary_10_1161_CIRCRESAHA_117_309732 crossref_primary_10_1111_eci_70082 crossref_primary_10_1002_joa3_13055 crossref_primary_10_1007_s11606_024_08848_x crossref_primary_10_3390_medicina54040058 crossref_primary_10_1002_joa3_13056 crossref_primary_10_1016_j_cjca_2022_01_023 crossref_primary_10_1016_j_jacc_2020_02_025 crossref_primary_10_1111_jce_16661 crossref_primary_10_1136_heartjnl_2017_312488 crossref_primary_10_3389_fcvm_2023_1141698 crossref_primary_10_1007_s11886_023_01910_w crossref_primary_10_1016_j_ccl_2019_01_004 crossref_primary_10_1038_s41598_022_21786_0 crossref_primary_10_1016_j_ccl_2019_01_001 crossref_primary_10_3389_fcvm_2023_1301412 crossref_primary_10_1002_clc_23452 crossref_primary_10_1016_j_hrtlng_2025_09_011 crossref_primary_10_1111_eci_70059 crossref_primary_10_7759_cureus_77404 crossref_primary_10_1016_j_hrthm_2025_03_2001 crossref_primary_10_1186_s12872_024_04202_5 crossref_primary_10_1016_j_cjca_2024_12_007 crossref_primary_10_1136_openhrt_2021_001823 crossref_primary_10_1016_S0140_6736_15_00333_5 crossref_primary_10_1016_j_biopha_2022_113002 crossref_primary_10_1016_j_jacc_2017_02_020 crossref_primary_10_1093_ejendo_lvaf183 crossref_primary_10_1093_ehjqcco_qcab096 crossref_primary_10_1371_journal_pone_0211228 crossref_primary_10_1007_s00380_020_01702_0 crossref_primary_10_3389_fcvm_2022_879139 crossref_primary_10_1111_pace_14591 crossref_primary_10_1016_j_ijcard_2017_02_039 crossref_primary_10_1038_s41598_019_49452_y crossref_primary_10_3390_s20216318 crossref_primary_10_3390_jcdd9030088 crossref_primary_10_3390_jcm10173846 crossref_primary_10_1001_jamanetworkopen_2021_21443 crossref_primary_10_1289_EHP392 crossref_primary_10_3389_fcvm_2025_1596574 crossref_primary_10_1155_2022_2090309 crossref_primary_10_1136_heartjnl_2020_317735 crossref_primary_10_3389_fcvm_2023_1068269 crossref_primary_10_1007_s10840_024_01854_3 crossref_primary_10_1016_j_phymed_2015_10_011 crossref_primary_10_1111_jce_15595 crossref_primary_10_1161_CIRCEP_118_006273 crossref_primary_10_1097_MD_0000000000021681 crossref_primary_10_1186_s12889_022_12628_9 crossref_primary_10_1136_heartjnl_2018_313630 crossref_primary_10_1007_s12020_017_1385_3 crossref_primary_10_1177_1755738018824361 crossref_primary_10_1111_anec_70044 crossref_primary_10_1161_CIRCRESAHA_121_319893 crossref_primary_10_1186_s12967_024_05028_7 crossref_primary_10_1002_clc_23231 crossref_primary_10_1016_j_medcle_2023_10_013 crossref_primary_10_1016_j_ijcard_2016_07_220 crossref_primary_10_1016_j_ijcard_2016_09_071 crossref_primary_10_1016_j_jns_2019_02_027 crossref_primary_10_1016_j_amjcard_2019_05_029 crossref_primary_10_3390_jcm13216592 crossref_primary_10_1038_s41598_024_76426_6 crossref_primary_10_3390_genes13010011 crossref_primary_10_1016_j_medcli_2023_10_008 crossref_primary_10_1016_j_chpulm_2024_100132 crossref_primary_10_1093_eurjcn_zvae164 crossref_primary_10_1007_s10840_025_01993_1 crossref_primary_10_1159_000457809 crossref_primary_10_1161_CIR_0000000000000757 crossref_primary_10_1111_jce_16674 crossref_primary_10_1093_eurheartj_ehx598 crossref_primary_10_1136_bmjgh_2021_006809 crossref_primary_10_5604_01_3001_0014_2844 crossref_primary_10_1097_MRR_0000000000000232 crossref_primary_10_1249_MSS_0000000000003424 crossref_primary_10_3390_s23094372 crossref_primary_10_15829_1728_8800_2019_4_109_114 crossref_primary_10_1186_s12875_018_0796_4 crossref_primary_10_3389_fcvm_2024_1385223 crossref_primary_10_1136_heartjnl_2020_316624 crossref_primary_10_1186_s12877_024_05059_1 crossref_primary_10_1093_eurheartj_ehw233 crossref_primary_10_1093_eurheartj_ehy411 crossref_primary_10_61186_hsm_4_2_92 crossref_primary_10_1161_HYPERTENSIONAHA_120_16659 crossref_primary_10_1093_eurheartj_ehad375 crossref_primary_10_1161_HYPERTENSIONAHA_121_17399 crossref_primary_10_3389_fcvm_2022_866260 crossref_primary_10_1161_CIRCEP_119_007428 crossref_primary_10_1177_09544119211029745 crossref_primary_10_1177_00033197221079331 crossref_primary_10_26599_1671_5411_2025_07_007 crossref_primary_10_1080_14779072_2016_1179581 crossref_primary_10_1016_j_ijcard_2022_05_048 crossref_primary_10_1016_j_rec_2023_05_004 crossref_primary_10_3390_jcm10112238 crossref_primary_10_1093_ageing_afaa268 crossref_primary_10_1136_openhrt_2021_001624 crossref_primary_10_2147_IPRP_S397844 crossref_primary_10_1186_s12944_020_01392_7 crossref_primary_10_1186_s43044_024_00518_x crossref_primary_10_1016_j_hrthm_2023_07_061 crossref_primary_10_3389_fendo_2025_1429465 crossref_primary_10_1016_j_hrthm_2024_10_046 crossref_primary_10_1161_CIR_0000000000000973 crossref_primary_10_1136_heartjnl_2019_316315 crossref_primary_10_1016_j_ijcard_2017_02_073 crossref_primary_10_1016_j_rcl_2023_12_016 crossref_primary_10_1038_s41598_022_04897_6 crossref_primary_10_3390_nu16142277 crossref_primary_10_1080_03007995_2020_1865892 crossref_primary_10_1093_eurjcn_zvad093 crossref_primary_10_1097_MS9_0000000000002858 crossref_primary_10_1007_s40140_015_0138_1 crossref_primary_10_18087_cardio_2020_1_n828 crossref_primary_10_1289_EHP4883 crossref_primary_10_1093_eurheartj_ehx389 crossref_primary_10_1161_JAHA_123_032215 crossref_primary_10_1186_s12872_021_02278_x crossref_primary_10_1136_heartjnl_2016_310843 crossref_primary_10_26599_TST_2022_9010008 crossref_primary_10_3390_jcm13082277 crossref_primary_10_1161_JAHA_120_018557 crossref_primary_10_1371_journal_pone_0231254 crossref_primary_10_1161_JAHA_123_030030 crossref_primary_10_1016_j_amjcard_2025_02_030 crossref_primary_10_1007_s13577_024_01145_z crossref_primary_10_1002_acn3_50936 crossref_primary_10_1016_j_ihj_2021_06_018 crossref_primary_10_1016_j_jtcvs_2018_03_017 crossref_primary_10_1097_GH9_0000000000000318 crossref_primary_10_2337_dc22_1188 crossref_primary_10_1016_j_ihj_2016_06_006 crossref_primary_10_3390_medicina58020187 crossref_primary_10_1080_07853890_2021_1930137 crossref_primary_10_18501_arrhythmia_2017_030 crossref_primary_10_1016_j_thromres_2019_11_010 crossref_primary_10_1016_j_amjmed_2020_02_012 crossref_primary_10_2147_JPR_S517820 crossref_primary_10_3389_fcvm_2024_1425159 crossref_primary_10_3390_jcdd10020076 crossref_primary_10_1161_JAHA_118_009543 crossref_primary_10_1038_s41598_023_47025_8 crossref_primary_10_3389_fpubh_2023_1137230 crossref_primary_10_1186_s12913_021_06882_7 crossref_primary_10_7759_cureus_85634 crossref_primary_10_1016_j_amjcard_2017_01_032 crossref_primary_10_1093_eurheartj_ehz782 crossref_primary_10_1016_j_bspc_2024_107480 crossref_primary_10_1002_cam4_4105 crossref_primary_10_1002_mrm_28001 crossref_primary_10_1161_CIRCULATIONAHA_115_018614 crossref_primary_10_3390_cells13040311 crossref_primary_10_1007_s00335_022_09964_x crossref_primary_10_1016_j_jacep_2022_02_014 crossref_primary_10_1161_CIRCOUTCOMES_117_003669 crossref_primary_10_1007_s11427_024_2674_2 crossref_primary_10_1161_JAHA_118_010756 crossref_primary_10_1371_journal_pone_0283942 crossref_primary_10_1016_j_ejmg_2022_104459 crossref_primary_10_1016_j_envint_2016_04_039 crossref_primary_10_1016_j_hrthm_2015_12_032 crossref_primary_10_1111_pace_14742 crossref_primary_10_1111_pace_14984 crossref_primary_10_1093_eurjcn_zvae141 crossref_primary_10_1038_srep31477 crossref_primary_10_1093_eurheartj_ehw045 crossref_primary_10_1016_j_jss_2019_01_017 crossref_primary_10_5507_pol_2020_008 crossref_primary_10_1080_14779072_2023_2172402 crossref_primary_10_1136_bmj_q826 crossref_primary_10_1161_JAHA_120_019412 crossref_primary_10_3389_fcvm_2023_1213672 crossref_primary_10_1097_MD_0000000000015892 crossref_primary_10_1007_s00392_022_02000_7 crossref_primary_10_1002_clc_24135 crossref_primary_10_1161_JAHA_124_040352 crossref_primary_10_1016_j_ccep_2018_02_015 crossref_primary_10_1016_j_amjmed_2017_07_003 crossref_primary_10_1038_s41598_023_47770_w crossref_primary_10_1161_CIRCEP_124_013261 crossref_primary_10_12968_bjon_2017_26_22_1245 crossref_primary_10_1002_jmri_70103 crossref_primary_10_1161_HYPERTENSIONAHA_119_13708 crossref_primary_10_1186_s12872_022_02865_6 crossref_primary_10_1111_ijcp_12804 crossref_primary_10_1186_s13063_024_08527_6 crossref_primary_10_1161_CIR_0000000000000350 crossref_primary_10_1002_ejhf_2443 crossref_primary_10_1007_s40258_016_0295_5 crossref_primary_10_1186_s12872_024_04094_5 crossref_primary_10_3390_jcdd10080336 crossref_primary_10_1016_j_banm_2020_07_049 crossref_primary_10_1002_clc_70064 crossref_primary_10_3389_fneur_2023_1302020 crossref_primary_10_1016_j_yjmcc_2023_01_006 crossref_primary_10_3389_fcell_2023_1190273 crossref_primary_10_1007_s00059_019_04842_w crossref_primary_10_1016_j_cjca_2022_04_009 crossref_primary_10_1097_MCA_0000000000000785 crossref_primary_10_1161_CIR_0000000000001209 crossref_primary_10_1161_JAHA_116_003408 crossref_primary_10_1016_j_acvd_2019_02_003 crossref_primary_10_1177_1074248418769638 crossref_primary_10_3390_medicina61040649 crossref_primary_10_23736_S0022_4707_22_13913_7 crossref_primary_10_1371_journal_pone_0175405 crossref_primary_10_1111_ggi_13451 crossref_primary_10_1016_j_ijcard_2017_04_081 crossref_primary_10_1161_CIRCOUTCOMES_119_005918 crossref_primary_10_1002_clc_70058 crossref_primary_10_1038_s41598_023_38071_3 crossref_primary_10_1016_j_jemermed_2022_07_016 crossref_primary_10_1186_s13578_023_01169_2 crossref_primary_10_1007_s10840_018_0356_9 crossref_primary_10_1136_bmjopen_2017_019933 crossref_primary_10_1016_j_ijcard_2019_12_023 crossref_primary_10_3390_biom13121690 crossref_primary_10_1002_ajh_24366 crossref_primary_10_1016_j_wneu_2024_123652 crossref_primary_10_1111_jgs_17886 crossref_primary_10_1016_j_atherosclerosis_2017_10_007 crossref_primary_10_1093_ehjqcco_qcad001 crossref_primary_10_2147_RMHP_S360285 crossref_primary_10_2147_JIR_S488288 crossref_primary_10_3390_jcdd10020082 crossref_primary_10_3390_life11090928 crossref_primary_10_1016_j_ejim_2020_09_005 crossref_primary_10_1177_2047487319841940 crossref_primary_10_1186_s12872_024_04019_2 crossref_primary_10_1016_j_cjca_2022_10_013 crossref_primary_10_1080_17476348_2023_2279236 crossref_primary_10_1016_j_hrthm_2017_07_001 crossref_primary_10_1371_journal_pone_0276369 crossref_primary_10_1016_j_amjcard_2020_10_023 crossref_primary_10_1093_eurjpc_zwac234 crossref_primary_10_1186_s12872_021_02043_0 crossref_primary_10_1016_S0140_6736_17_31072_3 crossref_primary_10_1177_0271678X18793324 crossref_primary_10_1111_anec_13013 crossref_primary_10_1038_s41371_019_0279_7 crossref_primary_10_15829_1728_8800_2021_2847 crossref_primary_10_1016_j_cjca_2024_07_007 crossref_primary_10_1177_1747493019891516 crossref_primary_10_1016_j_aan_2023_06_007 crossref_primary_10_1097_HPC_0000000000000109 crossref_primary_10_1161_JAHA_122_025653 crossref_primary_10_1016_j_hrthm_2025_07_053 crossref_primary_10_1038_nrcardio_2015_194 crossref_primary_10_1161_STROKEAHA_120_030601 crossref_primary_10_1161_JAHA_118_011346 crossref_primary_10_1016_j_amjcard_2020_05_009 crossref_primary_10_1007_s11886_022_01769_3 crossref_primary_10_1016_j_numecd_2021_12_001 crossref_primary_10_1016_j_rce_2017_04_002 crossref_primary_10_1016_j_jdiacomp_2018_02_004 crossref_primary_10_1016_S0140_6736_14_61991_7 crossref_primary_10_1016_j_cpha_2024_11_005 crossref_primary_10_1093_eurjpc_zwaa082 crossref_primary_10_1186_s12916_024_03400_4 crossref_primary_10_1038_nrcardio_2015_191 crossref_primary_10_1016_j_hrthm_2017_05_027 crossref_primary_10_1161_JAHA_121_023583 crossref_primary_10_1186_s12940_021_00813_z crossref_primary_10_1007_s00059_021_05090_7 crossref_primary_10_1002_joa3_12863 crossref_primary_10_1007_s11886_023_01862_1 crossref_primary_10_1186_s40001_025_03092_3 crossref_primary_10_1007_s10840_022_01341_7 crossref_primary_10_1016_j_jchf_2017_05_002 crossref_primary_10_1186_s12877_023_04330_1 crossref_primary_10_1007_s00380_021_01880_5 crossref_primary_10_1093_cvr_cvab073 crossref_primary_10_3390_jpm12030505 crossref_primary_10_1007_s10557_023_07491_8 crossref_primary_10_1177_17474930241261877 crossref_primary_10_1038_s41598_023_41942_4 crossref_primary_10_1096_fj_202300272R crossref_primary_10_1136_heartjnl_2023_323527 crossref_primary_10_15829_1560_4071_2019_7_12_18 crossref_primary_10_1177_23337214241304887 crossref_primary_10_3389_fphar_2021_680618 crossref_primary_10_1016_S1474_4422_17_30172_2 crossref_primary_10_1016_j_amjcard_2023_04_038 crossref_primary_10_1097_MD_0000000000039583 crossref_primary_10_1111_ane_13217 crossref_primary_10_3389_fcvm_2025_1587015 crossref_primary_10_1177_1074248419868996 crossref_primary_10_1093_eurheartj_ehad738 crossref_primary_10_1016_j_amjcard_2017_06_055 crossref_primary_10_1016_j_heliyon_2023_e21740 crossref_primary_10_1016_j_hlc_2022_04_049 crossref_primary_10_3390_jcm12196256 crossref_primary_10_3390_ijerph18052237 crossref_primary_10_3390_jcm11071823 crossref_primary_10_1097_MJT_0000000000001464 crossref_primary_10_1111_pace_12969 crossref_primary_10_3390_jcm7100370 crossref_primary_10_1093_fampra_cmab057 crossref_primary_10_1007_s10840_018_0441_0 crossref_primary_10_1053_j_jvca_2024_06_012 crossref_primary_10_1093_eurheartj_ehaa1078 crossref_primary_10_1016_j_ijcard_2018_08_038 crossref_primary_10_1093_eurheartj_ehz151 crossref_primary_10_1371_journal_pone_0205104 crossref_primary_10_1161_STROKEAHA_117_013369 crossref_primary_10_3390_jcm13237310 crossref_primary_10_1161_CIRCULATIONAHA_116_023650 crossref_primary_10_3389_fonc_2024_1301327 crossref_primary_10_1093_cvr_cvab095 crossref_primary_10_1016_j_jtha_2023_10_028 crossref_primary_10_1097_MD_0000000000026020 crossref_primary_10_15829_1728_8800_2022_3159 crossref_primary_10_3390_jcm9020414 crossref_primary_10_1161_CIR_0000000000001193 crossref_primary_10_1016_j_ccep_2020_11_013 crossref_primary_10_1186_s12872_021_02322_w crossref_primary_10_1093_eurjpc_zwac270 crossref_primary_10_1177_2050312118759444 crossref_primary_10_1113_JP273123 crossref_primary_10_1253_circj_CJ_23_0890 crossref_primary_10_1016_j_pharmthera_2023_108388 crossref_primary_10_1111_1753_0407_12580 crossref_primary_10_3390_jpm14060571 crossref_primary_10_1007_s40615_024_01917_1 crossref_primary_10_1016_j_jacep_2023_01_029 crossref_primary_10_1038_s41598_019_41977_6 crossref_primary_10_3389_fneur_2022_900582 crossref_primary_10_3390_jcm10040729 crossref_primary_10_1111_joim_13025 crossref_primary_10_7759_cureus_55241 crossref_primary_10_1161_JAHA_123_033740 crossref_primary_10_1016_j_ccep_2020_11_003 crossref_primary_10_7759_cureus_27849 crossref_primary_10_1016_j_ccep_2020_11_006 crossref_primary_10_1161_JAHA_124_040325 crossref_primary_10_1111_pace_12907 crossref_primary_10_3389_fgene_2025_1450259 crossref_primary_10_1093_eurjcn_zvaa014 crossref_primary_10_15420_aer_2018_75_2 crossref_primary_10_1136_heartjnl_2023_323737 crossref_primary_10_1016_j_hrthm_2020_05_004 crossref_primary_10_1093_ejcts_ezaf244 crossref_primary_10_1136_bmjopen_2020_042518 crossref_primary_10_15829_1560_4071_2021_4594 crossref_primary_10_1097_MD_0000000000003102 crossref_primary_10_1177_09544119251330742 crossref_primary_10_1016_j_amjcard_2017_06_007 crossref_primary_10_1097_HJH_0000000000002623 crossref_primary_10_1016_j_tcm_2025_08_004 crossref_primary_10_1093_ije_dyv337 crossref_primary_10_1007_s12603_020_1507_0 crossref_primary_10_1186_s42444_024_00119_4 crossref_primary_10_1016_j_jacep_2022_08_018 crossref_primary_10_1186_s40001_022_00738_4 crossref_primary_10_1016_j_hlc_2017_07_005 crossref_primary_10_2478_prolas_2020_0001 crossref_primary_10_1016_j_jhep_2022_07_030 crossref_primary_10_1016_j_ahj_2016_02_011 crossref_primary_10_1016_j_bpj_2024_02_004 crossref_primary_10_1186_s12872_025_04720_w crossref_primary_10_1007_s00392_018_1393_1 crossref_primary_10_1159_000498895 crossref_primary_10_1016_j_rccar_2017_11_022 crossref_primary_10_7759_cureus_12341 crossref_primary_10_1111_ene_15126 crossref_primary_10_3390_app15094633 crossref_primary_10_1111_jce_14952 crossref_primary_10_1021_acssensors_4c03477 crossref_primary_10_1016_j_ijcard_2018_10_070 crossref_primary_10_1186_s13019_025_03378_x crossref_primary_10_1186_s42444_022_00061_3 crossref_primary_10_1007_s00392_020_01763_1 crossref_primary_10_1038_s41569_019_0179_0 crossref_primary_10_1002_tre_898 crossref_primary_10_1016_j_ihj_2022_04_006 crossref_primary_10_1161_CIRCEP_118_007281 crossref_primary_10_1007_s10654_022_00914_0 crossref_primary_10_1007_s12181_024_00694_9 crossref_primary_10_1016_j_diabet_2023_101475 crossref_primary_10_1016_j_jtha_2024_08_009 crossref_primary_10_1093_eurjpc_zwaf371 crossref_primary_10_1007_s11239_023_02838_2 crossref_primary_10_1161_JAHA_119_012554 crossref_primary_10_1016_j_ijcard_2025_133846 crossref_primary_10_1093_eurjpc_zwae045 crossref_primary_10_3390_bioengineering12020149 crossref_primary_10_1016_j_hrthm_2025_08_014 crossref_primary_10_1016_j_ajem_2021_08_082 crossref_primary_10_1016_j_ijcard_2016_05_013 crossref_primary_10_1161_CIRCRESAHA_120_316340 crossref_primary_10_1038_s41598_025_91737_y crossref_primary_10_1161_JAHA_117_006541 crossref_primary_10_1007_s40266_016_0363_4 crossref_primary_10_1016_j_carrev_2018_07_019 crossref_primary_10_1002_clc_22501 crossref_primary_10_1136_bmjopen_2023_080836 crossref_primary_10_1001_jamacardio_2025_2374 crossref_primary_10_1161_CIRCULATIONAHA_116_024921 crossref_primary_10_1186_s12885_019_6314_9 crossref_primary_10_1016_j_echo_2019_08_001 crossref_primary_10_1161_CIR_0000000000000950 crossref_primary_10_3390_ijms23179565 crossref_primary_10_1111_jce_14737 crossref_primary_10_1093_europace_euae195 crossref_primary_10_24060_2076_3093_2018_8_4_303_309 crossref_primary_10_1093_eurjpc_zwae035 crossref_primary_10_1080_13696998_2025_2543214 crossref_primary_10_15829_1560_4071_2023_5544 crossref_primary_10_1007_s12603_020_1418_0 crossref_primary_10_1038_nrcardio_2016_45 crossref_primary_10_1136_bmjopen_2018_021704 crossref_primary_10_1109_JTEHM_2021_3134160 crossref_primary_10_1186_s12872_022_03033_6 crossref_primary_10_1016_j_jacbts_2024_10_012 crossref_primary_10_1007_s00392_023_02157_9 crossref_primary_10_1016_j_amjcard_2021_02_014 crossref_primary_10_3389_fcvm_2025_1552417 crossref_primary_10_1007_s11936_019_0793_5 crossref_primary_10_1093_ehjcvp_pvx002 crossref_primary_10_1016_j_ijcard_2018_09_047 crossref_primary_10_3389_fcvm_2019_00115 crossref_primary_10_1016_j_jacc_2018_11_051 crossref_primary_10_1093_eurheartj_ehad571 crossref_primary_10_1007_s00380_021_01984_y crossref_primary_10_1161_CIRCULATIONAHA_120_047633 crossref_primary_10_1093_pubmed_fdz140 crossref_primary_10_3389_fcvm_2025_1549002 crossref_primary_10_1016_j_hrthm_2019_07_006 crossref_primary_10_1016_j_ijcard_2019_01_047 crossref_primary_10_1038_s41598_018_25111_6 crossref_primary_10_1016_j_archger_2016_12_001 crossref_primary_10_4254_wjh_v10_i10_761 crossref_primary_10_1161_JAHA_119_012546 crossref_primary_10_1016_j_chest_2018_12_021 crossref_primary_10_1161_CIRCEP_123_012534 crossref_primary_10_1186_s12872_022_02485_0 crossref_primary_10_1002_cam4_7067 crossref_primary_10_1371_journal_pone_0266939 crossref_primary_10_1097_FJC_0000000000000624 crossref_primary_10_3390_jcm8111897 crossref_primary_10_3390_nu14173652 crossref_primary_10_3390_ijms25063206 crossref_primary_10_1111_eci_13477 crossref_primary_10_1007_s00059_021_05050_1 crossref_primary_10_1016_j_jacep_2024_08_019 crossref_primary_10_1111_jce_16728 crossref_primary_10_1161_CIRCULATIONAHA_121_057533 crossref_primary_10_2147_CIA_S258634 crossref_primary_10_1016_j_cjca_2021_12_017 crossref_primary_10_1161_JAHA_124_037552 crossref_primary_10_1007_s11239_022_02763_w crossref_primary_10_1016_j_jbiomech_2024_112354 crossref_primary_10_1161_JAHA_124_036468 crossref_primary_10_3389_fphys_2021_673047 crossref_primary_10_1016_j_hrthm_2016_09_003 crossref_primary_10_1016_j_ahj_2018_03_003 crossref_primary_10_15420_aer_2018_18_2 crossref_primary_10_1007_s00059_017_4649_z crossref_primary_10_3389_fcvm_2021_769198 crossref_primary_10_1161_STROKEAHA_116_015071 crossref_primary_10_3390_jpm12040519 crossref_primary_10_1371_journal_pone_0301991 crossref_primary_10_1155_2017_2163610 crossref_primary_10_1016_j_rec_2024_04_008 crossref_primary_10_1111_jce_14775 crossref_primary_10_1161_JAHA_123_030409 crossref_primary_10_14797_mdcvj_1516 crossref_primary_10_1016_j_cmpb_2016_04_009 crossref_primary_10_3389_fcvm_2020_00003 crossref_primary_10_1007_s11239_016_1376_x crossref_primary_10_1016_j_ijcard_2020_05_078 crossref_primary_10_2147_TCRM_S395578 crossref_primary_10_1016_j_medcle_2022_09_001 crossref_primary_10_1002_clc_22771 crossref_primary_10_3390_jcdd10030104 crossref_primary_10_3390_ijms232012612 crossref_primary_10_1080_0886022X_2024_2401623 crossref_primary_10_1016_j_ijcard_2024_132682 crossref_primary_10_1093_cvr_cvz217 crossref_primary_10_1016_j_hrthm_2025_07_005 crossref_primary_10_4103_ATMR_ATMR_171_24 crossref_primary_10_1371_journal_pone_0291299 crossref_primary_10_1007_s10554_017_1179_y crossref_primary_10_1088_1757_899X_450_4_042004 crossref_primary_10_1634_theoncologist_2018_0476 crossref_primary_10_3390_jcm10163715 crossref_primary_10_1016_j_jelectrocard_2022_07_071 crossref_primary_10_1001_jamanetworkopen_2022_29808 crossref_primary_10_1155_2017_8075697 crossref_primary_10_3389_fcvm_2024_1434963 crossref_primary_10_1136_bmjgh_2023_013311 crossref_primary_10_1016_j_maturitas_2023_107784 crossref_primary_10_1016_j_ahj_2018_04_017 crossref_primary_10_1016_j_ijcard_2025_133862 crossref_primary_10_1161_JAHA_116_005155 crossref_primary_10_1016_j_heliyon_2024_e24052 crossref_primary_10_1093_ehjdh_ztaf054 crossref_primary_10_1007_s12350_018_01480_3 crossref_primary_10_1016_j_jchf_2017_04_004 crossref_primary_10_1111_1753_0407_12392 crossref_primary_10_1371_journal_pone_0169400 crossref_primary_10_1038_s41569_023_00857_3 crossref_primary_10_1016_j_wneu_2019_11_127 crossref_primary_10_1016_j_ahj_2022_01_013 crossref_primary_10_1111_jce_16739 crossref_primary_10_1007_s10840_022_01383_x crossref_primary_10_1093_eurheartj_ehae611 crossref_primary_10_3390_nu14173615 crossref_primary_10_1001_jamanetworkopen_2020_22190 crossref_primary_10_1080_1744666X_2023_2196013 crossref_primary_10_1016_j_ijcard_2022_06_019 crossref_primary_10_1016_j_oret_2020_06_019 crossref_primary_10_1016_j_jstrokecerebrovasdis_2023_107400 crossref_primary_10_1016_j_jacc_2018_11_018 crossref_primary_10_1007_s11096_023_01672_z crossref_primary_10_1016_j_numecd_2020_06_026 crossref_primary_10_1097_HJH_0000000000002250 crossref_primary_10_1186_s12911_025_02880_5 crossref_primary_10_1016_j_ipej_2023_04_001 |
| Cites_doi | 10.1093/aje/155.9.819 10.1001/jama.285.18.2370 10.1001/jama.1994.03510350050036 10.1016/S0140-6736(06)69208-8 10.1001/jama.2011.1474 10.1056/NEJMoa020265 10.1161/CIRCOUTCOMES.110.958165 10.1161/CIRCOUTCOMES.111.962688 10.1161/CIRCULATIONAHA.105.595140 10.1161/CIRCULATIONAHA.113.005119 10.1056/NEJMoa1105575 10.1161/01.CIR.98.10.946 10.1001/jama.2011.659 10.1056/NEJMsa053935 10.1056/NEJM199904223401601 10.1016/j.jacc.2006.11.045 10.2105/AJPH.41.3.279 10.1016/j.ijcard.2004.08.024 10.1093/eurheartj/ehm308 10.1093/eurheartj/ehs469 10.1001/jama.2014.7692 10.1016/j.amjcard.2013.05.063 10.1001/jama.286.12.1494 10.1093/europace/eur132 10.1001/jama.2010.650 10.1016/0091-7435(75)90037-7 10.1093/eurheartj/eht280 10.1001/jama.296.10.1242 |
| ContentType | Journal Article |
| Copyright | 2015 Elsevier Ltd Elsevier Ltd Copyright © 2015 Elsevier Ltd. All rights reserved. Copyright Elsevier Limited Jul 11, 2015 |
| Copyright_xml | – notice: 2015 Elsevier Ltd – notice: Elsevier Ltd – notice: Copyright © 2015 Elsevier Ltd. All rights reserved. – notice: Copyright Elsevier Limited Jul 11, 2015 |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7QL 7QP 7RV 7TK 7U7 7U9 7X7 7XB 88A 88C 88E 88G 88I 8AF 8AO 8C1 8C2 8FE 8FH 8FI 8FJ 8FK 8G5 ABUWG AEUYN AFKRA AN0 ASE AZQEC BBNVY BEC BENPR BHPHI C1K CCPQU DWQXO FPQ FYUFA GHDGH GNUQQ GUQSH H94 HCIFZ K6X K9- K9. KB0 KB~ LK8 M0R M0S M0T M1P M2M M2O M2P M7N M7P MBDVC NAPCQ PHGZM PHGZT PJZUB PKEHL PPXIY PQEST PQGLB PQQKQ PQUKI PRINS PSYQQ Q9U S0X 7X8 |
| DOI | 10.1016/S0140-6736(14)61774-8 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Bacteriology Abstracts (Microbiology B) Calcium & Calcified Tissue Abstracts Nursing & Allied Health Database Neurosciences Abstracts Toxicology Abstracts Virology and AIDS Abstracts Health & Medical Collection ProQuest Central (purchase pre-March 2016) Biology Database (Alumni Edition) Healthcare Administration Database (Alumni) Medical Database (Alumni Edition) Psychology Database (Alumni) Science Database (Alumni Edition) STEM Database ProQuest Pharma Collection Public Health Database Lancet Titles ProQuest SciTech Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Research Library ProQuest Central (Alumni) One Sustainability ProQuest Central UK/Ireland British Nursing Database British Nursing Index ProQuest Central Essentials - QC Biological Science Collection eLibrary ProQuest Central Natural Science Collection Environmental Sciences and Pollution Management ProQuest One Community College ProQuest Central Korea British Nursing Index (BNI) (1985 to Present) Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student ProQuest Research Library AIDS and Cancer Research Abstracts SciTech Premium Collection British Nursing Index Consumer Health Database ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Database (Alumni Edition) ProQuest Newsstand Professional Biological Sciences Consumer Health Database ProQuest Health & Medical Collection Healthcare Administration Database Medical Database Psychology Database Research Library Science Database Algology Mycology and Protozoology Abstracts (Microbiology C) Biological Science Database Research Library (Corporate) Nursing & Allied Health Premium ProQuest Central Premium ProQuest One Academic (New) ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) One Applied & Life Sciences ProQuest One Academic (retired) ProQuest One Academic UKI Edition ProQuest Central China ProQuest One Psychology ProQuest Central Basic SIRS Editorial MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest One Psychology Research Library Prep ProQuest Central Student ProQuest Central Essentials Lancet Titles elibrary ProQuest AP Science SciTech Premium Collection ProQuest Central China Environmental Sciences and Pollution Management ProQuest One Applied & Life Sciences ProQuest One Sustainability Health Research Premium Collection Natural Science Collection Health & Medical Research Collection Biological Science Collection ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest Newsstand Professional Virology and AIDS Abstracts ProQuest Science Journals (Alumni Edition) ProQuest Biological Science Collection ProQuest Family Health ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) Biological Science Database Neurosciences Abstracts ProQuest Hospital Collection (Alumni) Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest One Academic UKI Edition ProQuest Health Management (Alumni Edition) ProQuest Nursing & Allied Health Source (Alumni) ProQuest One Academic Calcium & Calcified Tissue Abstracts ProQuest One Academic (New) ProQuest One Academic Middle East (New) SIRS Editorial ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing Research Library (Alumni Edition) ProQuest Natural Science Collection ProQuest Pharma Collection ProQuest Family Health (Alumni Edition) ProQuest Biology Journals (Alumni Edition) ProQuest Central ProQuest Health & Medical Research Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Bacteriology Abstracts (Microbiology B) Algology Mycology and Protozoology Abstracts (Microbiology C) AIDS and Cancer Research Abstracts ProQuest Research Library ProQuest Public Health ProQuest Central Basic Toxicology Abstracts ProQuest Science Journals British Nursing Index with Full Text ProQuest Health Management British Nursing Index ProQuest Nursing & Allied Health Source ProQuest Psychology Journals (Alumni) ProQuest SciTech Collection ProQuest Medical Library ProQuest Psychology Journals ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE ProQuest One Psychology MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1474-547X |
| EndPage | 162 |
| ExternalDocumentID | 3739535071 25960110 10_1016_S0140_6736_14_61774_8 S0140673614617748 1_s2_0_S0140673614617748 |
| Genre | Research Support, Non-U.S. Gov't Journal Article Research Support, N.I.H., Extramural |
| GeographicLocations | United States |
| GeographicLocations_xml | – name: United States |
| GrantInformation | NIH, NHLBI, NINDS, Deutsche Forschungsgemeinschaft. |
| GrantInformation_xml | – fundername: NHLBI NIH HHS grantid: HL080025 – fundername: NHLBI NIH HHS grantid: 1U01HL105268-01 – fundername: NHLBI NIH HHS grantid: R01HL104156 – fundername: NINDS NIH HHS grantid: 6R01-NS-17950 – fundername: NINDS NIH HHS grantid: R01 NS017950 – fundername: NHLBI NIH HHS grantid: K23 HL114724 – fundername: NHLBI NIH HHS grantid: R01 HL080124 – fundername: NCRR NIH HHS grantid: KL2 RR031981 – fundername: NHLBI NIH HHS grantid: 1RC1HL101056 – fundername: NHLBI NIH HHS grantid: N01-HC-25195 |
| GroupedDBID | --- --K --M .1- .55 .CO .FO 0R~ 123 1B1 1P~ 1RT 1~5 29L 4.4 457 4G. 53G 5VS 7-5 71M 7RV 7X7 88E 88I 8AF 8AO 8C1 8C2 8FE 8FH 8FI 8FJ 8G5 9JM AABNK AAEDT AAEDW AAFWJ AAIKJ AAKOC AALRI AAMRU AAQFI AAQQT AATTM AAXKI AAXUO AAYWO ABBQC ABCQX ABFNM ABIVO ABJNI ABLJU ABMAC ABMZM ABOCM ABUFD ABUWG ACGFS ACGOD ACIEU ACIUM ACLOT ACPRK ACRLP ACVFH ADBBV ADCNI AEIPS AEKER AENEX AEUPX AEUYN AEVXI AFKRA AFPUW AFRAH AFRHN AFTJW AFXIZ AGAPS AGHFR AHHHB AHMBA AIIUN AITUG AJRQY AJUYK AKBMS AKRWK AKYEP ALMA_UNASSIGNED_HOLDINGS AMRAJ AN0 ANZVX APXCP AQUVI AXJTR AZQEC BBNVY BCU BEC BENPR BHPHI BKEYQ BKNYI BKOJK BKOMP BNPGV BNQBC BPHCQ BVXVI CCPQU CS3 DU5 DWQXO EAU EBS EFJIC EFKBS EJD EO8 EO9 EP2 EP3 EWM EX3 F5P FD8 FDB FIRID FNPLU FYGXN FYUFA G-2 G-Q GBLVA GNUQQ GUQSH HCIFZ HMCUK IHE J1W K-O K9- KOM L7B LK8 LZ2 M0R M0T M1P M2M M2O M2P M7P MJL MO0 N9A NAPCQ O-L O9- OD. OO~ OZT P-8 P-9 P2P PC. PHGZM PHGZT PJZUB PPXIY PQGLB PQQKQ PRG PROAC PSQYO PSYQQ R2- ROL RPZ S0X SAD SDG SEL SES SJFOW SJN SPCBC SSH SSZ T5K TLN TWZ UAP UBE UKHRP UQL UV1 WOW X7M XAX XDU YYM Z5R ZMT ~HD .GJ 04C 3EH 3O- 3V. 41~ 88A 8WZ A6W AACTN AAEJM AAKAS AAQXK AAYOK ABDBF ABTAH ABWVN ACRPL ACRZS ACUHS ADMUD ADNMO ADZCM AFCTW AFFNX AFKWA AHQJS AJJEV AJOXV AKVCP ALIPV AMFUW ARTTT ASPBG AVWKF AZFZN D0S EAP EAS EAZ EBC EBD EBU EGS EHN EIHBH EMB EMK EMOBN ENC EPL EPS EPT ESX EVS FEDTE FGOYB HVGLF HZ~ J5H M0L M41 MVM OVD PKN Q~Q RIG SDF SV3 TEORI TH9 UHU WOQ WUQ XPP YYQ ZGI ZXP ZY4 ~G0 ABLVK ABYKQ AHPSJ AJBFU XFK ZA5 9DU AAYXX ADXHL AFFHD AGQPQ AIGII CITATION AGCQF AGRNS CGR CUY CVF ECM EIF NPM 7QL 7QP 7TK 7U7 7U9 7XB 8FK ASE C1K FPQ H94 K6X K9. KB~ M7N MBDVC PKEHL PQEST PQUKI PRINS Q9U 7X8 PUEGO |
| ID | FETCH-LOGICAL-c572t-2a524ca33c215c359ba28541fdf9d3f8a3b43d57295df80970493ca9fa9beca3 |
| IEDL.DBID | M7P |
| ISICitedReferencesCount | 1301 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000357742200032&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 0140-6736 1474-547X |
| IngestDate | Thu Oct 02 10:13:12 EDT 2025 Tue Oct 28 08:15:18 EDT 2025 Mon Jul 21 05:57:27 EDT 2025 Sat Nov 29 05:12:29 EST 2025 Tue Nov 18 21:23:02 EST 2025 Fri Feb 23 02:24:38 EST 2024 Sun Feb 23 10:19:31 EST 2025 Tue Oct 14 19:40:39 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 9989 |
| Language | English |
| License | Copyright © 2015 Elsevier Ltd. All rights reserved. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c572t-2a524ca33c215c359ba28541fdf9d3f8a3b43d57295df80970493ca9fa9beca3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| PMID | 25960110 |
| PQID | 1695230519 |
| PQPubID | 40246 |
| PageCount | 9 |
| ParticipantIDs | proquest_miscellaneous_1698027555 proquest_journals_1695230519 pubmed_primary_25960110 crossref_primary_10_1016_S0140_6736_14_61774_8 crossref_citationtrail_10_1016_S0140_6736_14_61774_8 elsevier_sciencedirect_doi_10_1016_S0140_6736_14_61774_8 elsevier_clinicalkeyesjournals_1_s2_0_S0140673614617748 elsevier_clinicalkey_doi_10_1016_S0140_6736_14_61774_8 |
| PublicationCentury | 2000 |
| PublicationDate | 2015-07-11 |
| PublicationDateYYYYMMDD | 2015-07-11 |
| PublicationDate_xml | – month: 07 year: 2015 text: 2015-07-11 day: 11 |
| PublicationDecade | 2010 |
| PublicationPlace | England |
| PublicationPlace_xml | – name: England – name: London |
| PublicationTitle | The Lancet (British edition) |
| PublicationTitleAlternate | Lancet |
| PublicationYear | 2015 |
| Publisher | Elsevier Ltd Elsevier Limited |
| Publisher_xml | – name: Elsevier Ltd – name: Elsevier Limited |
| References | Rowan, Bailey, Bublitz, Anderson (bib18) 2007; 49 Dawber, Meadors, Moore (bib12) 1951; 41 Koton, Schneider, Rosamond (bib19) 2014; 312 Miyasaka, Barnes, Gersh (bib1) 2006; 114 Nkomo, Gardin, Skelton, Gottdiener, Scott, Enriquez-Sarano (bib22) 2006; 368 Conen, Chae, Glynn (bib26) 2011; 305 Friberg, Hammar, Pettersson, Rosenqvist (bib17) 2007; 28 Piccini, Hammill, Sinner (bib10) 2012; 5 Feinleib, Kannel, Garrison, McNamara, Castelli (bib13) 1975; 4 Chen, Normand, Wang, Krumholz (bib30) 2011; 306 Okin, Wachtell, Devereux (bib27) 2006; 296 Colilla, Crow, Petkun, Singer, Simon, Liu (bib11) 2013; 112 Wattigney, Mensah, Croft (bib5) 2002; 155 Benjamin, Wolf, D'Agostino, Silbershatz, Kannel, Levy (bib20) 1998; 98 Abbott RD, McGee DL. The Framingham Study: an epidemiological investigation of cardiovascular disease. Section 37: the probability of developing certain cardiovascular diseases in eight years at specified values of some characteristics. Bethesda, MD: 1987. Krijthe, Kunst, Benjamin (bib2) 2013; 34 Kim, Johnston, Chu, Dalal, Schulman (bib6) 2011; 4 Cameron, Trivedi (bib15) 1998 Mosterd, D'Agostino, Silbershatz (bib24) 1999; 340 Egan, Zhao, Axon (bib25) 2010; 303 Stefansdottir, Aspelund, Gudnason, Arnar (bib8) 2011; 13 Benjamin, Levy, Vaziri, D'Agostino, Belanger, Wolf (bib21) 1994; 271 Chugh, Havmoeller, Narayanan (bib3) 2014; 129 Andersson, Magnuson, Bryngelsson (bib4) 2013; 34 Healey, Connolly, Gold (bib28) 2012; 366 Ford, Ajani, Croft (bib29) 2007; 356 Levy, Kenchaiah, Larson (bib23) 2002; 347 Ghali, Quan, Brant (bib16) 2001; 286 Frost, Vestergaard, Mosekilde, Mortensen (bib9) 2005; 103 Go, Hylek, Phillips (bib7) 2001; 285 Andersson (10.1016/S0140-6736(14)61774-8_bib4) 2013; 34 Rowan (10.1016/S0140-6736(14)61774-8_bib18) 2007; 49 Levy (10.1016/S0140-6736(14)61774-8_bib23) 2002; 347 Frost (10.1016/S0140-6736(14)61774-8_bib9) 2005; 103 Miyasaka (10.1016/S0140-6736(14)61774-8_bib1) 2006; 114 Conen (10.1016/S0140-6736(14)61774-8_bib26) 2011; 305 Krijthe (10.1016/S0140-6736(14)61774-8_bib2) 2013; 34 Benjamin (10.1016/S0140-6736(14)61774-8_bib20) 1998; 98 Okin (10.1016/S0140-6736(14)61774-8_bib27) 2006; 296 Cameron (10.1016/S0140-6736(14)61774-8_bib15) 1998 Kim (10.1016/S0140-6736(14)61774-8_bib6) 2011; 4 Koton (10.1016/S0140-6736(14)61774-8_bib19) 2014; 312 Feinleib (10.1016/S0140-6736(14)61774-8_bib13) 1975; 4 Nkomo (10.1016/S0140-6736(14)61774-8_bib22) 2006; 368 Dawber (10.1016/S0140-6736(14)61774-8_bib12) 1951; 41 10.1016/S0140-6736(14)61774-8_bib14 Friberg (10.1016/S0140-6736(14)61774-8_bib17) 2007; 28 Egan (10.1016/S0140-6736(14)61774-8_bib25) 2010; 303 Wattigney (10.1016/S0140-6736(14)61774-8_bib5) 2002; 155 Mosterd (10.1016/S0140-6736(14)61774-8_bib24) 1999; 340 Colilla (10.1016/S0140-6736(14)61774-8_bib11) 2013; 112 Chugh (10.1016/S0140-6736(14)61774-8_bib3) 2014; 129 Go (10.1016/S0140-6736(14)61774-8_bib7) 2001; 285 Piccini (10.1016/S0140-6736(14)61774-8_bib10) 2012; 5 Stefansdottir (10.1016/S0140-6736(14)61774-8_bib8) 2011; 13 Ghali (10.1016/S0140-6736(14)61774-8_bib16) 2001; 286 Benjamin (10.1016/S0140-6736(14)61774-8_bib21) 1994; 271 Healey (10.1016/S0140-6736(14)61774-8_bib28) 2012; 366 Ford (10.1016/S0140-6736(14)61774-8_bib29) 2007; 356 Chen (10.1016/S0140-6736(14)61774-8_bib30) 2011; 306 25960109 - Lancet. 2015 Jul 11;386(9989):113-5. doi: 10.1016/S0140-6736(14)61991-7. |
| References_xml | – volume: 5 start-page: 85 year: 2012 end-page: 93 ident: bib10 article-title: Incidence and prevalence of atrial fibrillation and associated mortality among Medicare beneficiaries, 1993–2007 publication-title: Circ Cardiovasc Qual Outcomes – volume: 4 start-page: 518 year: 1975 end-page: 525 ident: bib13 article-title: The Framingham Offspring Study. Design and preliminary data publication-title: Prev Med – volume: 368 start-page: 1005 year: 2006 end-page: 1011 ident: bib22 article-title: Burden of valvular heart diseases: a population-based study publication-title: Lancet – volume: 129 start-page: 837 year: 2014 end-page: 847 ident: bib3 article-title: Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study publication-title: Circulation – volume: 155 start-page: 819 year: 2002 end-page: 826 ident: bib5 article-title: Increased atrial fibrillation mortality: United States, 1980–1998 publication-title: Am J Epidemiol – volume: 34 start-page: 2746 year: 2013 end-page: 2751 ident: bib2 article-title: Projections on the number of individuals with atrial fibrillation in the European Union, from 2000 to 2060 publication-title: Eur Heart J – volume: 103 start-page: 78 year: 2005 end-page: 84 ident: bib9 article-title: Trends in incidence and mortality in the hospital diagnosis of atrial fibrillation or flutter in Denmark, 1980–1999 publication-title: Int J Cardiol – reference: Abbott RD, McGee DL. The Framingham Study: an epidemiological investigation of cardiovascular disease. Section 37: the probability of developing certain cardiovascular diseases in eight years at specified values of some characteristics. Bethesda, MD: 1987. – volume: 112 start-page: 1142 year: 2013 end-page: 1174 ident: bib11 article-title: Estimates of current and future incidence and prevalence of atrial fibrillation in the U.S. adult population publication-title: Am J Cardiol – volume: 114 start-page: 119 year: 2006 end-page: 125 ident: bib1 article-title: Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence publication-title: Circulation – volume: 13 start-page: 1110 year: 2011 end-page: 1117 ident: bib8 article-title: Trends in the incidence and prevalence of atrial fibrillation in Iceland and future projections publication-title: Europace – year: 1998 ident: bib15 publication-title: Regression analysis of count data – volume: 285 start-page: 2370 year: 2001 end-page: 2457 ident: bib7 article-title: Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study publication-title: JAMA – volume: 41 start-page: 279 year: 1951 end-page: 281 ident: bib12 article-title: Epidemiological approaches to heart disease: the Framingham Study publication-title: Am J Public Health Nations Health – volume: 98 start-page: 946 year: 1998 end-page: 952 ident: bib20 article-title: Impact of atrial fibrillation on the risk of death: the Framingham Heart Study publication-title: Circulation – volume: 49 start-page: 1561 year: 2007 end-page: 1565 ident: bib18 article-title: Trends in anticoagulation for atrial fibrillation in the U.S.: an analysis of the national ambulatory medical care survey database publication-title: J Am Coll Cardiol – volume: 347 start-page: 1397 year: 2002 end-page: 1402 ident: bib23 article-title: Long-term trends in the incidence of and survival with heart failure publication-title: N Engl J Med – volume: 303 start-page: 2043 year: 2010 end-page: 2050 ident: bib25 article-title: US trends in prevalence, awareness, treatment, and control of hypertension, 1988–2008 publication-title: JAMA – volume: 28 start-page: 2346 year: 2007 end-page: 2353 ident: bib17 article-title: Increased mortality in paroxysmal atrial fibrillation: report from the Stockholm Cohort-Study of Atrial Fibrillation (SCAF) publication-title: Eur Heart J – volume: 286 start-page: 1494 year: 2001 end-page: 1497 ident: bib16 article-title: Comparison of 2 methods for calculating adjusted survival curves from proportional hazards models publication-title: JAMA – volume: 366 start-page: 120 year: 2012 end-page: 129 ident: bib28 article-title: Subclinical atrial fibrillation and the risk of stroke publication-title: N Engl J Med – volume: 34 start-page: 1061 year: 2013 end-page: 1067 ident: bib4 article-title: All-cause mortality in 272 186 patients hospitalized with incident atrial fibrillation 1995–2008: a Swedish nationwide long-term case-control study publication-title: Eur Heart J – volume: 4 start-page: 313 year: 2011 end-page: 320 ident: bib6 article-title: Estimation of total incremental health care costs in patients with atrial fibrillation in the United States publication-title: Circ Cardiovasc Qual Outcomes – volume: 312 start-page: 259 year: 2014 end-page: 268 ident: bib19 article-title: Stroke incidence and mortality trends in US communities, 1987 to 2011 publication-title: JAMA – volume: 296 start-page: 1242 year: 2006 end-page: 1248 ident: bib27 article-title: Regression of electrocardiographic left ventricular hypertrophy and decreased incidence of new-onset atrial fibrillation in patients with hypertension publication-title: JAMA – volume: 306 start-page: 1669 year: 2011 end-page: 1678 ident: bib30 article-title: National and regional trends in heart failure hospitalization and mortality rates for Medicare beneficiaries, 1998–2008 publication-title: JAMA – volume: 271 start-page: 840 year: 1994 end-page: 844 ident: bib21 article-title: Independent risk factors for atrial fibrillation in a population-based cohort. The Framingham Heart Study publication-title: JAMA – volume: 340 start-page: 1221 year: 1999 end-page: 1227 ident: bib24 article-title: Trends in the prevalence of hypertension, antihypertensive therapy, and left ventricular hypertrophy from 1950 to 1989 publication-title: N Engl J Med – volume: 356 start-page: 2388 year: 2007 end-page: 2398 ident: bib29 article-title: Explaining the decrease in U.S. deaths from coronary disease, 1980–2000 publication-title: N Engl J Med – volume: 305 start-page: 2080 year: 2011 end-page: 2087 ident: bib26 article-title: Risk of death and cardiovascular events in initially healthy women with new-onset atrial fibrillation publication-title: JAMA – volume: 155 start-page: 819 year: 2002 ident: 10.1016/S0140-6736(14)61774-8_bib5 article-title: Increased atrial fibrillation mortality: United States, 1980–1998 publication-title: Am J Epidemiol doi: 10.1093/aje/155.9.819 – volume: 285 start-page: 2370 year: 2001 ident: 10.1016/S0140-6736(14)61774-8_bib7 article-title: Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study publication-title: JAMA doi: 10.1001/jama.285.18.2370 – volume: 271 start-page: 840 year: 1994 ident: 10.1016/S0140-6736(14)61774-8_bib21 article-title: Independent risk factors for atrial fibrillation in a population-based cohort. The Framingham Heart Study publication-title: JAMA doi: 10.1001/jama.1994.03510350050036 – year: 1998 ident: 10.1016/S0140-6736(14)61774-8_bib15 – volume: 368 start-page: 1005 year: 2006 ident: 10.1016/S0140-6736(14)61774-8_bib22 article-title: Burden of valvular heart diseases: a population-based study publication-title: Lancet doi: 10.1016/S0140-6736(06)69208-8 – volume: 306 start-page: 1669 year: 2011 ident: 10.1016/S0140-6736(14)61774-8_bib30 article-title: National and regional trends in heart failure hospitalization and mortality rates for Medicare beneficiaries, 1998–2008 publication-title: JAMA doi: 10.1001/jama.2011.1474 – volume: 347 start-page: 1397 year: 2002 ident: 10.1016/S0140-6736(14)61774-8_bib23 article-title: Long-term trends in the incidence of and survival with heart failure publication-title: N Engl J Med doi: 10.1056/NEJMoa020265 – volume: 4 start-page: 313 year: 2011 ident: 10.1016/S0140-6736(14)61774-8_bib6 article-title: Estimation of total incremental health care costs in patients with atrial fibrillation in the United States publication-title: Circ Cardiovasc Qual Outcomes doi: 10.1161/CIRCOUTCOMES.110.958165 – volume: 5 start-page: 85 year: 2012 ident: 10.1016/S0140-6736(14)61774-8_bib10 article-title: Incidence and prevalence of atrial fibrillation and associated mortality among Medicare beneficiaries, 1993–2007 publication-title: Circ Cardiovasc Qual Outcomes doi: 10.1161/CIRCOUTCOMES.111.962688 – volume: 114 start-page: 119 year: 2006 ident: 10.1016/S0140-6736(14)61774-8_bib1 article-title: Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.105.595140 – ident: 10.1016/S0140-6736(14)61774-8_bib14 – volume: 129 start-page: 837 year: 2014 ident: 10.1016/S0140-6736(14)61774-8_bib3 article-title: Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.113.005119 – volume: 366 start-page: 120 year: 2012 ident: 10.1016/S0140-6736(14)61774-8_bib28 article-title: Subclinical atrial fibrillation and the risk of stroke publication-title: N Engl J Med doi: 10.1056/NEJMoa1105575 – volume: 98 start-page: 946 year: 1998 ident: 10.1016/S0140-6736(14)61774-8_bib20 article-title: Impact of atrial fibrillation on the risk of death: the Framingham Heart Study publication-title: Circulation doi: 10.1161/01.CIR.98.10.946 – volume: 305 start-page: 2080 year: 2011 ident: 10.1016/S0140-6736(14)61774-8_bib26 article-title: Risk of death and cardiovascular events in initially healthy women with new-onset atrial fibrillation publication-title: JAMA doi: 10.1001/jama.2011.659 – volume: 356 start-page: 2388 year: 2007 ident: 10.1016/S0140-6736(14)61774-8_bib29 article-title: Explaining the decrease in U.S. deaths from coronary disease, 1980–2000 publication-title: N Engl J Med doi: 10.1056/NEJMsa053935 – volume: 340 start-page: 1221 year: 1999 ident: 10.1016/S0140-6736(14)61774-8_bib24 article-title: Trends in the prevalence of hypertension, antihypertensive therapy, and left ventricular hypertrophy from 1950 to 1989 publication-title: N Engl J Med doi: 10.1056/NEJM199904223401601 – volume: 49 start-page: 1561 year: 2007 ident: 10.1016/S0140-6736(14)61774-8_bib18 article-title: Trends in anticoagulation for atrial fibrillation in the U.S.: an analysis of the national ambulatory medical care survey database publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2006.11.045 – volume: 41 start-page: 279 year: 1951 ident: 10.1016/S0140-6736(14)61774-8_bib12 article-title: Epidemiological approaches to heart disease: the Framingham Study publication-title: Am J Public Health Nations Health doi: 10.2105/AJPH.41.3.279 – volume: 103 start-page: 78 year: 2005 ident: 10.1016/S0140-6736(14)61774-8_bib9 article-title: Trends in incidence and mortality in the hospital diagnosis of atrial fibrillation or flutter in Denmark, 1980–1999 publication-title: Int J Cardiol doi: 10.1016/j.ijcard.2004.08.024 – volume: 28 start-page: 2346 year: 2007 ident: 10.1016/S0140-6736(14)61774-8_bib17 article-title: Increased mortality in paroxysmal atrial fibrillation: report from the Stockholm Cohort-Study of Atrial Fibrillation (SCAF) publication-title: Eur Heart J doi: 10.1093/eurheartj/ehm308 – volume: 34 start-page: 1061 year: 2013 ident: 10.1016/S0140-6736(14)61774-8_bib4 article-title: All-cause mortality in 272 186 patients hospitalized with incident atrial fibrillation 1995–2008: a Swedish nationwide long-term case-control study publication-title: Eur Heart J doi: 10.1093/eurheartj/ehs469 – volume: 312 start-page: 259 year: 2014 ident: 10.1016/S0140-6736(14)61774-8_bib19 article-title: Stroke incidence and mortality trends in US communities, 1987 to 2011 publication-title: JAMA doi: 10.1001/jama.2014.7692 – volume: 112 start-page: 1142 year: 2013 ident: 10.1016/S0140-6736(14)61774-8_bib11 article-title: Estimates of current and future incidence and prevalence of atrial fibrillation in the U.S. adult population publication-title: Am J Cardiol doi: 10.1016/j.amjcard.2013.05.063 – volume: 286 start-page: 1494 year: 2001 ident: 10.1016/S0140-6736(14)61774-8_bib16 article-title: Comparison of 2 methods for calculating adjusted survival curves from proportional hazards models publication-title: JAMA doi: 10.1001/jama.286.12.1494 – volume: 13 start-page: 1110 year: 2011 ident: 10.1016/S0140-6736(14)61774-8_bib8 article-title: Trends in the incidence and prevalence of atrial fibrillation in Iceland and future projections publication-title: Europace doi: 10.1093/europace/eur132 – volume: 303 start-page: 2043 year: 2010 ident: 10.1016/S0140-6736(14)61774-8_bib25 article-title: US trends in prevalence, awareness, treatment, and control of hypertension, 1988–2008 publication-title: JAMA doi: 10.1001/jama.2010.650 – volume: 4 start-page: 518 year: 1975 ident: 10.1016/S0140-6736(14)61774-8_bib13 article-title: The Framingham Offspring Study. Design and preliminary data publication-title: Prev Med doi: 10.1016/0091-7435(75)90037-7 – volume: 34 start-page: 2746 year: 2013 ident: 10.1016/S0140-6736(14)61774-8_bib2 article-title: Projections on the number of individuals with atrial fibrillation in the European Union, from 2000 to 2060 publication-title: Eur Heart J doi: 10.1093/eurheartj/eht280 – volume: 296 start-page: 1242 year: 2006 ident: 10.1016/S0140-6736(14)61774-8_bib27 article-title: Regression of electrocardiographic left ventricular hypertrophy and decreased incidence of new-onset atrial fibrillation in patients with hypertension publication-title: JAMA doi: 10.1001/jama.296.10.1242 – reference: 25960109 - Lancet. 2015 Jul 11;386(9989):113-5. doi: 10.1016/S0140-6736(14)61991-7. |
| SSID | ssj0004605 |
| Score | 2.6729598 |
| Snippet | Comprehensive long-term data on atrial fibrillation trends in men and women are scant. We aimed to provide such data through analysis of the Framingham cohort... Summary Background Comprehensive long-term data on atrial fibrillation trends in men and women are scant. We aimed to provide such data through analysis of the... |
| SourceID | proquest pubmed crossref elsevier |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 154 |
| SubjectTerms | Age Distribution Aged Aged, 80 and over Atrial Fibrillation - epidemiology Atrial Fibrillation - etiology Cardiac arrhythmia Cardiology Cohort Studies Electrocardiography Female Humans Incidence Internal Medicine Male Middle Aged Mortality Mortality - trends Prevalence Risk Factors Sex Distribution Stroke - epidemiology Stroke - etiology Trends United States - epidemiology |
| Title | 50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study |
| URI | https://www.clinicalkey.com/#!/content/1-s2.0-S0140673614617748 https://www.clinicalkey.es/playcontent/1-s2.0-S0140673614617748 https://dx.doi.org/10.1016/S0140-6736(14)61774-8 https://www.ncbi.nlm.nih.gov/pubmed/25960110 https://www.proquest.com/docview/1695230519 https://www.proquest.com/docview/1698027555 |
| Volume | 386 |
| WOSCitedRecordID | wos000357742200032&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVPQU databaseName: Biological Science Database customDbUrl: eissn: 1474-547X dateEnd: 20250907 omitProxy: false ssIdentifier: ssj0004605 issn: 0140-6736 databaseCode: M7P dateStart: 19920104 isFulltext: true titleUrlDefault: http://search.proquest.com/biologicalscijournals providerName: ProQuest – providerCode: PRVPQU databaseName: Consumer Health Database customDbUrl: eissn: 1474-547X dateEnd: 20250907 omitProxy: false ssIdentifier: ssj0004605 issn: 0140-6736 databaseCode: M0R dateStart: 19920104 isFulltext: true titleUrlDefault: https://search.proquest.com/familyhealth providerName: ProQuest – providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 1474-547X dateEnd: 20250907 omitProxy: false ssIdentifier: ssj0004605 issn: 0140-6736 databaseCode: 7X7 dateStart: 19920104 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: Healthcare Administration Database customDbUrl: eissn: 1474-547X dateEnd: 20250907 omitProxy: false ssIdentifier: ssj0004605 issn: 0140-6736 databaseCode: M0T dateStart: 19920104 isFulltext: true titleUrlDefault: https://search.proquest.com/healthmanagement providerName: ProQuest – providerCode: PRVPQU databaseName: Nursing & Allied Health Database customDbUrl: eissn: 1474-547X dateEnd: 20250907 omitProxy: false ssIdentifier: ssj0004605 issn: 0140-6736 databaseCode: 7RV dateStart: 19920104 isFulltext: true titleUrlDefault: https://search.proquest.com/nahs providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: eissn: 1474-547X dateEnd: 20250907 omitProxy: false ssIdentifier: ssj0004605 issn: 0140-6736 databaseCode: BENPR dateStart: 19920104 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: Psychology Database customDbUrl: eissn: 1474-547X dateEnd: 20250907 omitProxy: false ssIdentifier: ssj0004605 issn: 0140-6736 databaseCode: M2M dateStart: 19920104 isFulltext: true titleUrlDefault: https://www.proquest.com/psychology providerName: ProQuest – providerCode: PRVPQU databaseName: Public Health Database customDbUrl: eissn: 1474-547X dateEnd: 20250907 omitProxy: false ssIdentifier: ssj0004605 issn: 0140-6736 databaseCode: 8C1 dateStart: 19920104 isFulltext: true titleUrlDefault: https://search.proquest.com/publichealth providerName: ProQuest – providerCode: PRVPQU databaseName: Research Library customDbUrl: eissn: 1474-547X dateEnd: 20250907 omitProxy: false ssIdentifier: ssj0004605 issn: 0140-6736 databaseCode: M2O dateStart: 19920104 isFulltext: true titleUrlDefault: https://search.proquest.com/pqrl providerName: ProQuest – providerCode: PRVPQU databaseName: Science Database customDbUrl: eissn: 1474-547X dateEnd: 20250907 omitProxy: false ssIdentifier: ssj0004605 issn: 0140-6736 databaseCode: M2P dateStart: 19920104 isFulltext: true titleUrlDefault: https://search.proquest.com/sciencejournals providerName: ProQuest |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3db9MwELfYhhAvfH8URmUkHkBatjiOG5sXBNOmPdBSjWrqm-XEjpi0pqXJkPYP8Hdz5zjZS8eQeDk1Tc6u4uvdz-f7IORdakqlrBQRdww2KCrloAeLOAKwkHMwcDbx0YRnX7PJRM7nahocbnUIq-x0olfUdlmgj_yAjRQ6MGGMT6ufEXaNwtPV0EJji-xglQTuQ_emm_IifYj7dQbPwff-y_cs_QBmPEsjeZNtugl7eht0_PB_f_0j8iCgT_q5FZfH5I6rnpB743C-_pT8FjG9AtmnjQ-VpecVNb6vBy0xNeCiDZyjqzUWCUedsEfRV2_bjximTkMDnz1qKksXHtwD0MeRAGpSwMkLMJY_zIKewDwNxTjGq4_UUOzUC9e-3O0zMjs-mh2eRKFTQ1SILGmixIgkLQznBaxCwYXKDWZmstKWyvJSGp6n3MKjSthSxiqDfQkvjCqNAhky_DnZrpaVe0ko9kJmljGbuhyQnsxTJ_KRAxDrrGVKDUjaLZEuQhVzbKZxoTeEq7FU-5XVckD2e7ZVW8bjNoZRt_66y1EFrarB0NzGmG1idHXQDbVmuk503HIjM3ZWB1bglD1ngD8trPmXSXc7sdPX8_QyNyBv-9ugPfBIyFRueemfkXhwLcSAvGhFu38_sDEeITp89ffBX5P7ACIF-rsZ2yXbzfrSvSF3i1_Neb0ekq3s9AzpPPNUApWHbEh2vhxNpqdwNY5bOkOajD395ul06P_OfwCjcEAB |
| linkProvider | ProQuest |
| linkToHtml | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V3db9MwED-NgYAXvj8KA4wEEkgLi-O4iZEQQsDUaW2FRDXtzXJiR0xa09JmoP4D_Df8j9w5H3vpGC974K1pc3bqnO9-Z__OB_AiNoVSNpWBcBwDFBULtIN5GCBYyAQ6OBt5NuHBMBmP08ND9WUDfre5MESrbG2iN9R2ltMa-Q7vK1rAxDbez78HVDWKdlfbEhq1Wuy71U8M2Zbv9j7h-30ZRbufJx8HQVNVIMhlElVBZGQU50aIHL1dLqTKDGUR8sIWyooiNSKLhcVblbRFGqoEMbTIjSqMwv9rBDZ7CS7TsXrEIByFk3VpmJ5Rf5owtPO1-_IVj18jakjiID3LFZ4Fdb3L2735nw3WLbjRYGv2oZ4Mt2HDlXfg6qhhD9yFXzJkK3wqVnkiMDsqmfFVS1hBiQ_HNS2QzRd0BDpZvG1GOxG2_kgkfNaUJ9pmprRs6kMXDGOoJQTSDKOAKUKBb2bKBthPxYiluXrLDKM6xHjtD_O9B5OLGIT7sFnOSvcQGFV65pZzG7sMcWyaxU5mfYcQ3VnLlepB3GqEzpsz2qlUyLFeQ8bjsfaKpNMevOnE5vUhJecJ9Ft1020GLvoMjW70PMFknaBbNpZvqbleRjqspUmY6sajKEqmnWQD7mrQ9i-dbrVark_76VS8B8-7n9E20oaXKd3sxN-T0ra8lD14UM-kbnww7O8T9n3098afwbXBZDTUw73x_mO4jnBZ0so-51uwWS1O3BO4kv-ojpaLp94WMNAXPJ3-ACrOkrI |
| linkToPdf | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1fb9MwELfGQNNe-D8oDDASSCAttI7txkZCCG1UmzaqSUxob5YTO9qkNS1NBuoX4Dvx7bhz_uylY7zsgbemzdmNc777nf07HyGvhM21dkpG3DMIULTgYAezQQRgIeXg4Fwc2ITfDpLxWB0f68MV8rvNhUFaZWsTg6F20wzXyPtsqHEBE9ro5w0t4nBn9HH2PcIKUrjT2pbTqFVk3y9-QvhWftjbgXf9Oo5Hn4-2d6OmwkCUySSuotjKWGSW8ww8X8alTi1mFLLc5drxXFmeCu7gVi1drgY6ATzNM6tzq-HZLYdmb5CbCTwUssnUNluWkhnY9RfJQ_2v3ZdvmHgLCCIRkbrMLV4Ge4P7G935jwfuLrndYG76qZ4k98iKL-6TtS8Nq-AB-SUHdAH_ilaBIExPC2pDNROaY0LEWU0XpLM5Ho2OlnCL4g6Fqz8iOZ82ZYu2qC0cnYSQBsIbbAkANoXoYAIQ4cRO6C70U1Fkby7eU0uxPjFch0N-H5Kj6xiEDbJaTAv_mFCsAM0cY074FPCtSoWX6dADdPfOMa17RLTaYbLm7HYsIXJmlpD0mDBBqYzqkXed2Kw-vOQqgWGreqbNzAVfYsC9XiWYLBP0ZWMRS8NMGZtBLY3CWE8eREFSdZIN6KvB3L90utlqvLnop1P3HnnZ_Qw2EzfCbOGn5-Eehdv1UvbIo3pWdeMTS4jpARM_-XvjL8gazCJzsDfef0rWAUVLXPBnbJOsVvNz_4zcyn5Up-X8eTALlJhrnk1_ANitmzA |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=50+year+trends+in+atrial+fibrillation+prevalence%2C+incidence%2C+risk+factors%2C+and+mortality+in+the+Framingham+Heart+Study%3A+a+cohort+study&rft.jtitle=The+Lancet+%28British+edition%29&rft.au=Schnabel%2C+Renate+B%2C+Dr&rft.au=Yin%2C+Xiaoyan%2C+PhD&rft.au=Gona%2C+Philimon%2C+Phd&rft.au=Larson%2C+Martin+G%2C+ScD&rft.date=2015-07-11&rft.issn=0140-6736&rft.volume=386&rft.issue=9989&rft.spage=154&rft.epage=162&rft_id=info:doi/10.1016%2FS0140-6736%2814%2961774-8&rft.externalDBID=ECK1-s2.0-S0140673614617748&rft.externalDocID=1_s2_0_S0140673614617748 |
| thumbnail_m | http://cvtisr.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F01406736%2FS0140673615X61502%2Fcov150h.gif |