Coagulation and inflammation in scrub typhus and murine typhus—a prospective comparative study from Laos

Scrub typhus (caused by Orientia tsutsugamushi) and murine typhus (caused by Rickettsia typhi) cause up to 28% of febrile episodes in Thailand and Laos. The current understanding of coagulation and inflammation in the pathogenesis of these clinically very similar vasculotropic diseases is limited. T...

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Bibliographic Details
Published in:	Clinical microbiology and infection Vol. 18; no. 12; pp. 1221 - 1228
Main Authors:	Paris, D.H., Chansamouth, V., Nawtaisong, P., Löwenberg, E.C., Phetsouvanh, R., Blacksell, S.D., Lee, S.J., Dondorp, A.M., Newton, P.N., van der Poll, T., Levi, M., Day, N. P.J.
Format:	Journal Article
Language:	English
Published:	Oxford, UK Elsevier Ltd 01.12.2012 Blackwell Publishing Ltd Wiley-Blackwell Elsevier Limited
Subjects:	Adolescent Adult Aged Aged, 80 and over Bacterial diseases Biological and medical sciences Biomarkers - analysis Blood Coagulation Child Child, Preschool Coagulation Comparative studies Female Human bacterial diseases Humans Infectious Diseases inflammation Inflammation - pathology Laos Male Medical sciences Middle Aged murine typhus Orientia tsutsugamushi Orientia tsutsugamushi - pathogenicity pathophysiology Prospective Studies Rickettsia typhi Rickettsia typhi - pathogenicity Rickettsial diseases Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis scrub typhus Scrub Typhus - pathology Tropical bacterial diseases Typhus, Endemic Flea-Borne - pathology vasculitis Young Adult Asia Laos murine typhus inflammation vasculitis Coagulation pathophysiology Laos scrub typhus Scrub typhus Murine typhus Rickettsialosis Pathophysiology Cardiovascular disease Inflammation Infection Vascular disease Vasculitis Rickettsial infection Bacteriosis Comparative study
ISSN:	1198-743X, 1469-0691, 1469-0691
Online Access:	Get full text
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