Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

Atherosclerotic lesions are known for their cellular heterogeneity, yet the molecular complexity within the cells of human plaques has not been fully assessed. Using single-cell transcriptomics and chromatin accessibility, we gained a better understanding of the pathophysiology underlying human athe...

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Bibliographic Details

Published in:	Circulation research Vol. 127; no. 11; p. 1437
Main Authors:	Depuydt, Marie A C, Prange, Koen H M, Slenders, Lotte, Örd, Tiit, Elbersen, Danny, Boltjes, Arjan, de Jager, Saskia C A, Asselbergs, Folkert W, de Borst, Gert J, Aavik, Einari, Lönnberg, Tapio, Lutgens, Esther, Glass, Christopher K, den Ruijter, Hester M, Kaikkonen, Minna U, Bot, Ilze, Slütter, Bram, van der Laan, Sander W, Yla-Herttuala, Seppo, Mokry, Michal, Kuiper, Johan, de Winther, Menno P J, Pasterkamp, Gerard
Format:	Journal Article
Language:	English
Published:	United States 06.11.2020
Subjects:	atherosclerosis cardiovascular disease genome-wide association study single-cell analysis
ISSN:	1524-4571, 1524-4571
Online Access:	Get more information
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