Molecular epidemiology and pathogenicity of Wesselsbron virus circulating in Africa

•Twenty-five Wesselsbron virus isolates from Africa were successfully characterized.•First identification of recombination events on the genome of Wesselsbron virus.•The clade 1 Wesselsbron virus was more pathogenic and neurotropic in suckling mice.•The intramuscular route was the best transmission...

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Veröffentlicht in:	Virus research Jg. 350; S. 199499
Hauptverfasser:	Faye, Martin, Di Paola, Nicholas, Dia, Moussa, Sall, Amadou Alpha, Faye, Ousmane
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands Elsevier B.V 01.12.2024 Elsevier
Schlagworte:	Aedes Aedes - virology Africa Africa - epidemiology Animals evolution genome Genome, Viral Humans livestock Mice Molecular Epidemiology Mosquito Vectors - virology Pathogenicity Phylogeny Recombination, Genetic Rhabdoviridae Infections - epidemiology Rhabdoviridae Infections - veterinary Rhabdoviridae Infections - virology species teratogenicity Tropism West Africa vaccines Viral Tropism Virulence viruses Wesselsbron virus Whole Genome Sequencing zoonoses Africa Wesselsbron virus Pathogenicity Molecular epidemiology Tropism West Africa
ISSN:	0168-1702, 1872-7492, 1872-7492
Online-Zugang:	Volltext
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