An Updated Review of Macro, Micro, and Nanostructured Hydrogels for Biomedical and Pharmaceutical Applications

Hydrogels are materials with wide applications in several fields, including the biomedical and pharmaceutical industries. Their properties such as the capacity of absorbing great amounts of aqueous solutions without losing shape and mechanical properties, as well as loading drugs of different nature...

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Veröffentlicht in:Pharmaceutics Jg. 12; H. 10; S. 970
Hauptverfasser: Lima, Caroline S. A. de, Balogh, Tatiana S., Varca, Justine P. R. O., Varca, Gustavo H. C., Lugão, Ademar B., A. Camacho-Cruz, Luis, Bucio, Emilio, Kadlubowski, Slawomir S.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Switzerland MDPI AG 15.10.2020
MDPI
Schlagworte:
biomedical applications
Drug delivery systems
Hydrogels
Hydrogen bonds
macrogel
microgel
nanogel
pharmaceutical applications
Pharmaceuticals
Polymerization
Polymers
Review
Solvents
synthesis
synthesis
microgel
pharmaceutical applications
macrogel
biomedical applications
nanogel
ISSN:1999-4923, 1999-4923
Online-Zugang:Volltext
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Zusammenfassung:Hydrogels are materials with wide applications in several fields, including the biomedical and pharmaceutical industries. Their properties such as the capacity of absorbing great amounts of aqueous solutions without losing shape and mechanical properties, as well as loading drugs of different nature, including hydrophobic ones and biomolecules, give an idea of their versatility and promising demand. As they have been explored in a great number of studies for years, many routes of synthesis have been developed, especially for chemical/permanent hydrogels. In the same way, stimuli-responsive hydrogels, also known as intelligent materials, have been explored too, enhancing the regulation of properties such as targeting and drug release. By controlling the particle size, hydrogel on the micro- and nanoscale have been studied likewise and have increased, even more, the possibilities for applications of the so-called XXI century materials. In this paper, we aimed to produce an overview of the recent studies concerning methods of synthesis, biomedical, and pharmaceutical applications of macro-, micro, and nanogels.
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ISSN:1999-4923
1999-4923
DOI:10.3390/pharmaceutics12100970