Multivariate Modulation of the Zr MOF UiO‐66 for Defect‐Controlled Combination Anticancer Drug Delivery

Metal–organic frameworks (MOFs) are emerging as leading candidates for nanoscale drug delivery, as a consequence of their high drug capacities, ease of functionality, and the ability to carefully engineer key physical properties. Despite many anticancer treatment regimens consisting of a cocktail of...

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Bibliographic Details
Published in:	Angewandte Chemie International Edition Vol. 59; no. 13; pp. 5211 - 5217
Main Authors:	Abánades Lázaro, Isabel, Wells, Connor J. R., Forgan, Ross S.
Format:	Journal Article
Language:	English
Published:	Germany Wiley Subscription Services, Inc 23.03.2020 John Wiley and Sons Inc
Edition:	International ed. in English
Subjects:	Alendronate - chemistry Alendronate - pharmacology anticancer Anticancer properties Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Apoptosis - drug effects Biocompatibility Breast cancer Cancer Catalysis Coumaric Acids - chemistry Coumaric Acids - pharmacology Cytotoxicity Defects Dichloroacetic Acid - chemistry Dichloroacetic Acid - pharmacology Drug Compounding Drug delivery Drug delivery systems Drug Therapy, Combination Drugs Humans Ibuprofen - chemistry Ibuprofen - pharmacology MCF-7 Cells Metal clusters Metal-organic frameworks Metal-Organic Frameworks - chemistry microporous materials Modulation Multivariate analysis Nanocapsules - chemistry Nanoparticles Physical properties Porosity Toxicity Zirconium Zirconium - chemistry drug delivery microporous materials anticancer cytotoxicity metal-organic frameworks
ISSN:	1433-7851, 1521-3773, 1521-3773
Online Access:	Get full text
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