Catalytic Synthesis of Indolines by Hydrogen Atom Transfer to Cobalt(III)–Carbene Radicals

We report a new method for the synthesis of indolines from o‐aminobenzylidine N‐tosylhydrazones proceeding through a cobalt(III)–carbene radical intermediate. This methodology employs the use of inexpensive commercially available reagents and allows for the transformation of easily derivatized benza...

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Bibliographic Details
Published in:	Chemistry : a European journal Vol. 24; no. 20; pp. 5253 - 5258
Main Authors:	Karns, Alexander S., Goswami, Monalisa, de Bruin, Bas
Format:	Journal Article
Language:	English
Published:	WEINHEIM Wiley 06.04.2018 Wiley Subscription Services, Inc John Wiley and Sons Inc
Subjects:	Aniline Benzaldehyde carbenes Catalysis Chemical synthesis Chemistry Chemistry, Multidisciplinary Cobalt Computer applications Density functional theory Heterocyclic compounds indolines Intermediates metalloradicals Nitrogen Physical Sciences Precursors Radicals Reagents Science & Technology indolines SUBSTITUTED INDOLINES C(SP)-H BONDS radicals carbenes cobalt N-TOSYLHYDRAZONES MEDIATED INTRAMOLECULAR AMINATION ASYMMETRIC CYCLOPROPANATION metalloradicals METALLORADICAL CATALYSIS CARBENE COMPLEXES ARYL AMINATION C-H INSERTION ELECTRONIC-STRUCTURE
ISSN:	0947-6539, 1521-3765, 1521-3765
Online Access:	Get full text
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