oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes

SCOPE: Curcumin revealed various health‐beneficial properties in numerous studies. However its bioavailability is low due to its limited intestinal uptake and rapid metabolism. The aim of our project was to develop novel curcumin formulations with improved oral bioavailability and to study their saf...

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Veröffentlicht in:	Molecular nutrition & food research Jg. 58; H. 3; S. 516 - 527
Hauptverfasser:	Schiborr, Christina, Kocher, Alexa, Behnam, Dariush, Jandasek, Josef, Toelstede, Simone, Frank, Jan
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Weinheim Blackwell Publishing Ltd 01.03.2014 Wiley
Schlagworte:	absorption Administration, Oral Bioavailability Biological and medical sciences Biological Availability blood Cross-Over Studies Curcuma longa Curcumin Curcumin - adverse effects Curcumin - analogs & derivatives Curcumin - analysis Curcumin - metabolism Curcumin - pharmacokinetics Diarylheptanoids Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology gender differences Healthy humans Humans Male men Micelles Powders Safety Sex differences Sex Factors urine Vertebrates: anatomy and physiology, studies on body, several organs or systems women Young Adult Human Monocotyledones Curcuma longal Nutrition Tyrosine kinase inhibitor Toxicity Sex Oral administration Micelle Sex differences Healthy humans Bioavailability Powder Liquid Angiospermae Spermatophyta Curcumin Curcuma Safety Pharmacokinetics Zingiberaceae Curcuma longa
ISSN:	1613-4125, 1613-4133, 1613-4133
Online-Zugang:	Volltext
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