The clinical role of the TME in solid cancer

The highly complex and heterogenous ecosystem of a tumour not only contains malignant cells, but also interacting cells from the host such as endothelial cells, stromal fibroblasts, and a variety of immune cells that control tumour growth and invasion. It is well established that anti-tumour immunit...

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Bibliographic Details
Published in:	British journal of cancer Vol. 120; no. 1; pp. 45 - 53
Main Authors:	Giraldo, Nicolas A., Sanchez-Salas, Rafael, Peske, J. David, Vano, Yann, Becht, Etienne, Petitprez, Florent, Validire, Pierre, Ingels, Alexandre, Cathelineau, Xavier, Fridman, Wolf Herman, Sautès-Fridman, Catherine
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.01.2019 Nature Publishing Group Cancer Research UK
Subjects:	631/67/580/1884 692/4028/67/1059/2325 692/4028/67/327 692/53/2422 Biomedical and Life Sciences Biomedicine Cancer Cancer Research Cancer-Associated Fibroblasts - immunology Cancer-Associated Fibroblasts - pathology Cell Proliferation - genetics Colorectal cancer Colorectal carcinoma Cytotoxicity Drug Resistance Endothelial cells Endothelial Cells - immunology Endothelial Cells - pathology Epidemiology Fibroblasts Humans Immunotherapy Kidney cancer Life Sciences Lymphocytes T Melanoma Metastases Molecular Medicine Neoplasm Invasiveness - genetics Neoplasm Invasiveness - pathology Neoplasms - immunology Neoplasms - pathology Oncology Phenotypes Renal cell carcinoma Review Review Article Solid tumors T-Lymphocytes, Cytotoxic - immunology T-Lymphocytes, Cytotoxic - pathology Tumor Microenvironment - immunology Tumors
ISSN:	0007-0920, 1532-1827, 1532-1827
Online Access:	Get full text
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