A combined approach of MALDI-TOF mass spectrometry and multivariate analysis as a potential tool for the detection of SARS-CoV-2 virus in nasopharyngeal swabs

•This study with MALDI-TOF comprises, as far as we know, the first report describing the performance of this technology with COVID-19 diagnosis.•This work would encourage researchers to explore the potential of MALDI-TOF MS to assess the feasibility of this technology, as a rapid and reproducible sc...

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Bibliographic Details
Published in:	Journal of virological methods Vol. 286; p. 113991
Main Authors:	Rocca, María Florencia, Zintgraff, Jonathan Cristian, Dattero, María Elena, Santos, Leonardo Silva, Ledesma, Martín, Vay, Carlos, Prieto, Mónica, Benedetti, Estefanía, Avaro, Martín, Russo, Mara, Nachtigall, Fabiane Manke, Baumeister, Elsa
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.12.2020
Subjects:	Betacoronavirus - isolation & purification Clinical Laboratory Techniques - methods Coronavirus Infections - diagnosis Coronavirus Infections - virology COVID-19 COVID-19 infection COVID-19 Testing COVID-19 Vaccines Humans Machine Learning MALDI-TOF Mass Screening - methods Mass spectrometry matrix-assisted laser desorption-ionization mass spectrometry Multivariate Analysis Nasopharynx - virology Pandemics Pneumonia, Viral - diagnosis Pneumonia, Viral - virology Real-Time Polymerase Chain Reaction SARS-CoV-2 Sensitivity and Specificity Severe acute respiratory syndrome coronavirus 2 Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods viruses COVID-19 SARS-CoV-2 MALDI-TOF Mass spectrometry Machine learning
ISSN:	0166-0934, 1879-0984, 1879-0984
Online Access:	Get full text
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