Shared genetic effects between hepatic steatosis and fibrosis: A prospective twin study

Nonalcoholic fatty liver disease is associated with metabolic risk factors including hypertension and dyslipidemia and may progress to liver fibrosis. Studies have shown that hepatic steatosis and fibrosis are heritable, but whether they have a significant shared gene effect is unknown. This study e...

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Vydáno v:	Hepatology (Baltimore, Md.) Ročník 64; číslo 5; s. 1547 - 1558
Hlavní autoři:	Cui, Jeffrey, Chen, Chi‐Hua, Lo, Min‐Tzu, Schork, Nicholas, Bettencourt, Ricki, Gonzalez, Monica P., Bhatt, Archana, Hooker, Jonathan, Shaffer, Katherine, Nelson, Karen E., Long, Michelle T., Brenner, David A., Sirlin, Claude B., Loomba, Rohit, for the Genetics of NAFLD in Twins Consortium
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Wolters Kluwer Health, Inc 01.11.2016
Témata:	Blood pressure Body mass Body mass index Cross-Sectional Studies Diseases in Twins - genetics Diseases in Twins - metabolism Dyslipidemia Environmental effects Fatty liver Fatty Liver - genetics Fatty Liver - metabolism Female Fibrosis Hemoglobin Hepatology Humans Insulin Insulin resistance Liver Cirrhosis - genetics Liver Cirrhosis - metabolism Liver diseases Magnetic resonance imaging Male Metabolism Middle Aged NMR Nuclear magnetic resonance Pathogenesis Prospective Studies Risk Factors Steatosis Triglycerides Twin studies Twins
ISSN:	0270-9139, 1527-3350, 1527-3350
On-line přístup:	Získat plný text
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