The calcium-binding protein complex S100A8/A9 has a crucial role in controlling macrophage-mediated renal repair following ischemia/reperfusion

Upon ischemia/reperfusion (I/R)-induced injury, several damage-associated molecular patterns are expressed including the calcium-binding protein S100A8/A9 complex. S100A8/A9 can be recognized by Toll-like receptor-4 and its activation is known to deleteriously contribute to renal I/R-induced injury....

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Veröffentlicht in:	Kidney international Jg. 87; H. 1; S. 85 - 94
Hauptverfasser:	Dessing, Mark C., Tammaro, Alessandra, Pulskens, Wilco P., Teske, Gwendoline J., Butter, Loes M., Claessen, Nike, van Eijk, Marco, van der Poll, Tom, Vogl, Thomas, Roth, Johannes, Florquin, Sandrine, Leemans, Jaklien C.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Elsevier Inc 01.01.2015 Elsevier Limited
Schlagworte:	acute kidney injury Animals Calcium-Binding Proteins - physiology Calgranulin A - physiology Calgranulin B - physiology immunology and pathology inflammation ischemia/reperfusion Kidney - blood supply macrophages Macrophages - physiology Male Mice Mice, Knockout renal ischemia/reperfusion Reperfusion Injury - physiopathology Wound Healing - physiology ischemia/reperfusion immunology and pathology macrophages acute kidney injury renal ischemia/reperfusion inflammation
ISSN:	0085-2538, 1523-1755, 1523-1755
Online-Zugang:	Volltext
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