Effects of Thyroid Function on Hemostasis, Coagulation, and Fibrinolysis: A Mendelian Randomization Study

Untreated hypothyroidism is associated with acquired von Willebrand syndrome, and hyperthyroidism is associated with increased thrombosis risk. However, the causal effects of thyroid function on hemostasis, coagulation, and fibrinolysis are unknown. In a two-sample Mendelian randomization (MR) study...

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Veröffentlicht in:	Thyroid (New York, N.Y.) Jg. 31; H. 9; S. 1305
Hauptverfasser:	Ellervik, Christina, Mora, Samia, Kuś, Aleksander, Åsvold, Bjørn, Marouli, Eirini, Deloukas, Panos, Sterenborg, Rosalie B T M, Teumer, Alexander, Burgess, Stephen, Sabater-Lleal, Maria, Huffman, Jennifer, Johnson, Andrew D, Trégouet, David-Alexandre, Smith, Nicolas L, Medici, Marco, DeVries, Paul S, Chasman, Daniel I, Kjaergaard, Alisa D
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.09.2021
Schlagworte:	Autoantibodies - blood Biomarkers - blood Blood Coagulation - genetics Blood Coagulation Factors - analysis Blood Coagulation Tests Case-Control Studies Fibrinolysis - genetics Genetic Predisposition to Disease Genome-Wide Association Study Hemostasis - genetics Humans Hyperthyroidism - blood Hyperthyroidism - diagnosis Hyperthyroidism - genetics Hypothyroidism - blood Hypothyroidism - diagnosis Hypothyroidism - genetics Mendelian Randomization Analysis Phenotype Polymorphism, Single Nucleotide Risk Assessment Risk Factors Thyrotropin - blood Thyroxine - blood von Willebrand Factor - analysis fibrinolysis hyperthyroidism thyrotropin thyroid hormone hypothyroidism thyroid peroxidase antibody hemostasis coagulation
ISSN:	1557-9077, 1557-9077
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