Autoantibodies in Pandemrix®-induced narcolepsy: Nine candidate autoantigens fail the conformational autoantibody test

Study objectives: Narcolepsy type 1 (NT1) is a chronic sleep disorder characterized by loss of hypocretin-producing neurons. Increased NT1 incidence was observed in Sweden following mass-vaccination with Pandemrix ® . Genetic association to HLA DQB1*06:02 implies an autoimmune origin, but target aut...

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Bibliographic Details
Published in:	Autoimmunity (Chur, Switzerland) Vol. 52; no. 4; pp. 185 - 191
Main Authors:	Wallenius, Madeleine, Lind, Alexander, Akel, Omar, Karlsson, Emma, Svensson, Markus, Arvidsson, Elin, Ramelius, Anita, Törn, Carina, Palm, Lars, Lernmark, Åke, Elding Larsson, Helena
Format:	Journal Article
Language:	English
Published:	England Taylor & Francis 19.05.2019 Taylor & Francis Group
Subjects:	Adolescent Adult Aged Autoantibodies Autoantibodies - immunology Autoantigens - immunology autoimmunity Basic Medicine Child Clinical Medicine Female HLA-DQ beta-Chains - genetics Humans hypocretin/orexin Immunologi inom det medicinska området (Här ingår: Cell- och immunterapi) Immunology in the Medical Area (including Cell and Immunotherapy) Influenza Vaccines - adverse effects Klinisk medicin Male Mass Vaccination - adverse effects Medical and Health Sciences Medicin och hälsovetenskap Medicinska och farmaceutiska grundvetenskaper Middle Aged Narcolepsy - chemically induced Narcolepsy - immunology narcolepsy type 1 Pandemrix®-vaccination Radioligand Assay - methods Sweden Young Adult Sweden Pandemrix®-vaccination hypocretin/orexin Autoantibodies autoimmunity narcolepsy type 1
ISSN:	0891-6934, 1607-842X, 1607-842X
Online Access:	Get full text
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