Regression of liver fibrosis and hepatocellular carcinoma development after HCV eradication with oral antiviral agents

We prospectively investigated the changes of liver stiffness (LS) and the occurrence of hepatocellular carcinoma (HCC) after hepatitis C virus (HCV) eradication using direct antiviral agents (DAA) over three years. LS measurement using transient elastography and serum fibrosis surrogate markers befo...

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Bibliographic Details
Published in:	Scientific Reports Vol. 12; no. 1; pp. 193 - 9
Main Authors:	Yoo, Hae Won, Park, Jun Yong, Kim, Sang Gyune, Jung, Young Kul, Lee, Sae Hwan, Kim, Moon Young, Jun, Dae Won, Jang, Jae Young, Lee, Jin Woo, Kwon, Oh Sang
Format:	Journal Article
Language:	English
Published:	London Springer Science and Business Media LLC 07.01.2022 Nature Publishing Group UK Nature Publishing Group Nature Portfolio
Subjects:	692/4020/4021 692/699/1503/1607/1605 Administration Administration, Oral Aged Antiviral Agents Antiviral Agents - administration & dosage Antiviral Agents - adverse effects Antiviral drugs Carbamates Carbamates - administration & dosage Carcinoma Carcinoma, Hepatocellular Carcinoma, Hepatocellular - diagnosis Carcinoma, Hepatocellular - epidemiology Carcinoma, Hepatocellular - prevention & control Carcinoma, Hepatocellular - virology Chronic / diagnosis Chronic / drug therapy Chronic / epidemiology Chronic / virology Clinical trials Combination Drug Therapy Drug Therapy, Combination Elasticity Imaging Techniques Eradication Female Fibrosis Hepatitis C Hepatitis C, Chronic Hepatitis C, Chronic - diagnosis Hepatitis C, Chronic - drug therapy Hepatitis C, Chronic - epidemiology Hepatitis C, Chronic - virology Hepatocellular / diagnosis Hepatocellular / epidemiology Hepatocellular / prevention & control Hepatocellular / virology Hepatocellular carcinoma Humanities and Social Sciences Humans Imidazoles Imidazoles - administration & dosage Incidence Interferon Interferons Interferons - administration & dosage Isoquinolines Isoquinolines - administration & dosage Liver Liver cancer Liver Cirrhosis Liver Cirrhosis - diagnostic imaging Liver Cirrhosis - drug therapy Liver Cirrhosis - epidemiology Liver Cirrhosis - virology Liver Neoplasms Liver Neoplasms - diagnosis Liver Neoplasms - epidemiology Liver Neoplasms - prevention & control Liver Neoplasms - virology Male Medicine Middle Aged multidisciplinary Oral Patients Prospective Studies Pyrrolidines Pyrrolidines - administration & dosage Q R Retrospective Studies Ribavirin Ribavirin - administration & dosage Science Science (multidisciplinary) Seoul Sulfonamides Sulfonamides - administration & dosage Sustained Virologic Response Time Factors Treatment Outcome Valine Valine - administration & dosage Valine - analogs & derivatives Seoul
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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