Blood metabolites reflect the effect of gut microbiota on differentiated thyroid cancer: a Mendelian randomization analysis

Background Studies have linked gut microbiome and differentiated thyroid cancer (DTC). However, their causal relationships and potential mediating factors have not been well defined. Our study investigated the causal relationships between the gut microbiome, papillary thyroid cancer (PTC) and follic...

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Bibliographic Details
Published in:	BMC cancer Vol. 25; no. 1; pp. 368 - 10
Main Authors:	Zhang, Hanfei, Li, Yuhao, Li, Lin
Format:	Journal Article
Language:	English
Published:	London BioMed Central 28.02.2025 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Adenocarcinoma, Follicular - blood Adenocarcinoma, Follicular - genetics Adenocarcinoma, Follicular - microbiology Adenocarcinoma, Follicular - pathology Bayes Theorem Bayesian analysis Biomedical and Life Sciences Biomedicine Blood Blood metabolites Cancer Research Causes of Development and progression Follicular thyroid cancer Gastrointestinal Microbiome Gastrointestinal system Genome-wide association studies Genome-Wide Association Study Genomes Gut Microbiota Health aspects Health Promotion and Disease Prevention Humans Intestinal microflora Medicine/Public Health Mendelian randomization Mendelian Randomization Analysis Metabolic Networks and Pathways Metabolic pathways Metabolism Metabolites Microbiomes Microbiota Microbiota (Symbiotic organisms) Oncology Papillary thyroid cancer Physiological aspects Sensitivity analysis Sphingomyelin Statistical analysis Statistics Surgical Oncology Thyroid cancer Thyroid Cancer, Papillary - blood Thyroid Cancer, Papillary - genetics Thyroid Cancer, Papillary - microbiology Thyroid Cancer, Papillary - pathology Thyroid Neoplasms - blood Thyroid Neoplasms - genetics Thyroid Neoplasms - microbiology Thyroid Neoplasms - pathology China Mendelian randomization Papillary thyroid cancer Follicular thyroid cancer Gut Microbiota Blood metabolites
ISSN:	1471-2407, 1471-2407
Online Access:	Get full text
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