Potential of Mycobacterium tuberculosis resuscitation-promoting factors as antigens in novel tuberculosis sub-unit vaccines

Novel vaccines are needed to control tuberculosis (TB), the bacterial infectious disease that together with malaria and HIV is worldwide responsible for high levels of morbidity and mortality. TB can result from the reactivation of an initially controlled latent infection by Mycobacterium tuberculos...

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Bibliographic Details
Published in:	Microbes and infection Vol. 14; no. 1; pp. 86 - 95
Main Authors:	Romano, M., Aryan, E., Korf, H., Bruffaerts, N., Franken, C.L.M.C., Ottenhoff, T.H.M., Huygen, K.
Format:	Journal Article
Language:	English
Published:	Kidlington Elsevier Masson SAS 2012 Elsevier
Subjects:	Animals antigens Antigens, Bacterial - genetics Antigens, Bacterial - immunology Applied microbiology Bacterial Proteins - genetics Bacterial Proteins - immunology Bacteriology BCG Vaccine - immunology Biological and medical sciences cell-mediated immunity Cytokines - genetics Cytokines - immunology Epitopes - immunology Female Fundamental and applied biological sciences. Psychology Human immunodeficiency virus Humans immune response malaria Mice Mice, Inbred BALB C Mice, Inbred C57BL Microbiology Micrococcus luteus Micrococcus luteus - genetics Micrococcus luteus - immunology Miscellaneous morbidity mortality Mycobacterium bovis Mycobacterium bovis - genetics Mycobacterium bovis - immunology Mycobacterium bovis BCG Mycobacterium tuberculosis Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - immunology plasmids proteins recombinant vaccines Resuscitation-promoting factor Th1 Cells - immunology tuberculosis Tuberculosis - immunology Tuberculosis - pathology Tuberculosis - prevention & control Tuberculosis Vaccines - genetics Tuberculosis Vaccines - immunology vaccination Vaccine development Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Vaccines, DNA - genetics Vaccines, DNA - immunology Mycobacterium tuberculosis Vaccine development Resuscitation-promoting factor Antigen Mycobacteriales Mycobacteriaceae Bacteria Actinomycetes Vaccine Resuscitation
ISSN:	1286-4579, 1769-714X, 1769-714X
Online Access:	Get full text
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